Full Text Journal Articles by
Author Maroun J Mhanna

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The Risk of Mortality Differs Between Critically Ill Children Who Were Born at Near Term, Term, or Late Term Gestation.

Maroun J Mhanna, Aparna Roy,

Crit Care Med (Critical care medicine)
[2020, 48(8):1246-1247]

Cited: 0 times

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Low hemoglobin levels are independently associated with neonatal acute kidney injury: a report from the AWAKEN Study Group.

Arwa Nada, David Askenazi, Louis J Boohaker, Linzi Li, John D Mahan, Jennifer Charlton, Russell L Griffin, ,

<h4>Background</h4>Studies in adults showed a relationship between low hemoglobin (Hb) and acute kidney injury (AKI). We performed this study to evaluate this association in newborns.<h4>Methods</h4>We evaluated 1891 newborns from the Assessment of Worldwide AKI Epidemiology in Neonates (AWAKEN) database. We evaluated the associations for the entire cohort and 3 gestational ... Read more >>

Pediatr Res (Pediatric research)
[2020, :]

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Acute Kidney Injury is Associated with Poor Lung Outcomes in Infants Born ≥32 Weeks of Gestational Age.

Michelle C Starr, Louis Boohaker, Laurie C Eldredge, Shina Menon, Russell Griffin, Dennis Mayock, David Askenazi, Sangeeta Hingorani, ,

<h4>Objective</h4>This study aimed to evaluate the association between acute kidney injury (AKI) and lung outcomes in infants born ≥32 weeks of gestational age (GA).<h4>Study design</h4>Secondary analysis of infants ≥32 weeks of GA in the assessment of worldwide acute kidney injury epidemiology in neonates (AWAKEN) retrospective cohort (<i>n</i> = 1,348). We used logistic ... Read more >>

Am J Perinatol (American journal of perinatology)
[2020, 37(2):231-240]

Cited: 1 time

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Acute Kidney Injury and Bronchopulmonary Dysplasia in Premature Neonates Born Less than 32 Weeks' Gestation.

Michelle C Starr, Louis Boohaker, Laurie C Eldredge, Shina Menon, Russell Griffin, Dennis E Mayock, Linzi Li, David Askenazi, Sangeeta Hingorani, ,

OBJECTIVE:This study aimed to evaluate the association between acute kidney injury (AKI) and bronchopulmonary dysplasia (BPD) in infants born <32 weeks of gestational age (GA). STUDY DESIGN:Present study is a secondary analysis of premature infants born at <32 weeks of GA in the Assessment of Worldwide Acute Kidney Injury Epidemiology ... Read more >>

Am J Perinatol (American journal of perinatology)
[2020, 37(3):341-348]

Cited: 4 times

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The impact of fluid balance on outcomes in premature neonates: a report from the AWAKEN study group.

David T Selewski, Katja M Gist, Amy T Nathan, Stuart L Goldstein, Louis J Boohaker, Ayse Akcan-Arikan, Elizabeth M Bonachea, Mina Hanna, Catherine Joseph, John D Mahan, Cherry Mammen, Arwa Nada, Kimberly Reidy, Amy Staples, Pia Wintermark, Russell Griffin, David J Askenazi, Ronnie Guillet, ,

<h4>Background</h4>We evaluated the epidemiology of fluid balance (FB) over the first postnatal week and its impact on outcomes in a multi-center cohort of premature neonates from the AWAKEN study.<h4>Methods</h4>Retrospective analysis of infants <36 weeks' gestational age from the AWAKEN study (N = 1007). FB was defined by percentage of change from birth ... Read more >>

Pediatr Res (Pediatric research)
[2020, 87(3):550-557]

Cited: 2 times

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Correlation between Invasive and Noninvasive Blood Pressure Measurements in Extremely Low Gestational Age Newborns.

Krishna Kishore Umapathi, Maroun J Mhanna,

OBJECTIVE:This work aimed to study the correlation between invasive blood pressure (IBP) and non-IBP (NIBP) in extremely low gestational age newborns (ELGANs) during their first 72 hours of life. STUDY DESIGN:In a retrospective cohort study, IBP and simultaneous NIBP measurements during the first 72 hours of life were recorded in ... Read more >>

Am J Perinatol (American journal of perinatology)
[2020, 37(5):548-552]

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Correction to: Acute kidney injury in neonatal encephalopathy: an evaluation of the AWAKEN database.

Megan J Kirkley, Louis Boohaker, Russell Griffin, Danielle E Soranno, Jason Gien, David Askenazi, Katja M Gist, ,

The original version of this article unfortunately contained a mistake. The collaborators of the Neonatal Kidney Collaborative (NKC) were not named individually. The list of all collaborators is given below. ... Read more >>

Pediatr Nephrol (Pediatric nephrology (Berlin, Germany))
[2019, 34(2):363]

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Incidence and Risk Factors of Early Onset Neonatal AKI.

Jennifer R Charlton, Louis Boohaker, David Askenazi, Patrick D Brophy, Carl D'Angio, Mamta Fuloria, Jason Gien, Russell Griffin, Sangeeta Hingorani, Susan Ingraham, Ayesa Mian, Robin K Ohls, Shantanu Rastogi, Christopher J Rhee, Mary Revenis, Subrata Sarkar, Alexandra Smith, Michelle Starr, Alison L Kent, ,

<h4>Background and objectives</h4>Neonatal AKI is associated with poor short- and long-term outcomes. The objective of this study was to describe the risk factors and outcomes of neonatal AKI in the first postnatal week.<h4>Design, setting, participants, & measurements</h4>The international retrospective observational cohort study, Assessment of Worldwide AKI Epidemiology in Neonates (AWAKEN), ... Read more >>

Clin J Am Soc Nephrol (Clinical journal of the American Society of Nephrology : CJASN)
[2019, 14(2):184-195]

Cited: 2 times

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Late onset neonatal acute kidney injury: results from the AWAKEN Study.

Jennifer R Charlton, Louis Boohaker, David Askenazi, Patrick D Brophy, Mamta Fuloria, Jason Gien, Russell Griffin, Sangeeta Hingorani, Susan Ingraham, Ayesa Mian, Robin K Ohls, Shantanu Rastogi, Christopher J Rhee, Mary Revenis, Subrata Sarkar, Michelle Starr, Alison L Kent, ,

BACKGROUND:Most studies of neonatal acute kidney injury (AKI) have focused on the first week following birth. Here, we determined the outcomes and risk factors for late AKI (>7d). METHODS:The international AWAKEN study examined AKI in neonates admitted to an intensive care unit. Late AKI was defined as occurring >7 days ... Read more >>

Pediatr Res (Pediatric research)
[2019, 85(3):339-348]

Cited: 3 times

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Serum neurotrophins at birth correlate with respiratory and neurodevelopmental outcomes of premature infants.

Samantha L Simpson, Stephanie Grayson, Jennifer H Peterson, John J Moore, Maroun J Mhanna, Miriam K Perez, Fariba Rezaee, Giovanni Piedimonte,

OBJECTIVE:Preterm birth is a significant cause of infant morbidity and mortality, which are primarily the result of respiratory and neurodevelopmental complications. However, no objective biomarker is currently available to predict at birth the risk and severity of such complications. Thus, we sought to determine whether serum neurotrophins concentrations measured at ... Read more >>

Pediatr Pulmonol (Pediatric pulmonology)
[2019, 54(3):303-312]

Cited: 0 times

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Airway pressure release ventilation versus conventional ventilation for the management of pediatric acute respiratory distress syndrome: do we have an answer?

Krishna Kishore Umapathi, Maroun J Mhanna,

J Thorac Dis (Journal of thoracic disease)
[2018, 10(Suppl 33):S4085-S4087]

Cited: 0 times

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The impact of fluid balance on outcomes in critically ill near-term/term neonates: a report from the AWAKEN study group.

David T Selewski, Ayse Akcan-Arikan, Elizabeth M Bonachea, Katja M Gist, Stuart L Goldstein, Mina Hanna, Catherine Joseph, John D Mahan, Arwa Nada, Amy T Nathan, Kimberly Reidy, Amy Staples, Pia Wintermark, Louis J Boohaker, Russell Griffin, David J Askenazi, Ronnie Guillet, ,

<h4>Background</h4>In sick neonates admitted to the NICU, improper fluid balance can lead to fluid overload. We report the impact of fluid balance in the first postnatal week on outcomes in critically ill near-term/term neonates.<h4>Methods</h4>This analysis includes infants ≥36 weeks gestational age from the Assessment of Worldwide Acute Kidney injury Epidemiology ... Read more >>

Pediatr Res (Pediatric research)
[2019, 85(1):79-85]

Cited: 1 time

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Usefulness of Assessment of Stool Form by the Modified Bristol Stool Form Scale in Primary Care Pediatrics.

Reema Gulati, Arpitha Komuravelly, Stephen Leb, Maroun J Mhanna, Abdullah Ghori, Janeen Leon, Robert Needlman,

<h4>Purpose</h4>Rome criteria are considered the gold standard for diagnosing functional constipation. The modified Bristol stool form scale (m-BSFS) was validated to measure stool form in children. However, neither the potential use of the m-BSFS as a tool to facilitate the diagnosis of potential constipation, nor the agreement between m-BSFS and ... Read more >>

Pediatr Gastroenterol Hepatol Nutr (Pediatric gastroenterology, hepatology & nutrition)
[2018, 21(2):93-100]

Cited: 0 times

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Incidence of neonatal hypertension from a large multicenter study [Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates-AWAKEN].

Emily J Kraut, Louis J Boohaker, David J Askenazi, Jeffery Fletcher, Alison L Kent, ,

BACKGROUND:Hypertension occurs in up to 3% of neonates admitted to the Neonatal Intensive Care Unit (NICU), and is a potentially under-recognized condition. The aim of this study was to examine the incidence of documented and undiagnosed hypertension from the 24-center Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates (AWAKEN) ... Read more >>

Pediatr Res (Pediatric research)
[2018, 84(2):279-289]

Cited: 2 times

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Fluid Overload and Renal Angina Index at Admission Are Associated With Worse Outcomes in Critically Ill Children.

Sidharth K Sethi, Veena Raghunathan, Shilpi Shah, Maninder Dhaliwal, Pranaw Jha, Maneesh Kumar, Sravanthi Paluri, Shyam Bansal, Maroun J Mhanna, Rupesh Raina,

Objectives: We investigated the association of fluid overload and oxygenation in critically sick children, and their correlation with various outcomes (duration of ventilation, ICU stay, and mortality). We also assessed whether renal angina index (RAI) at admission can predict mortality or acute kidney injury (AKI) on day 3 after admission. ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2018, 6:118]

Cited: 2 times

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Assessment of neonatal adrenal size using high resolution 2D ultrasound and its correlation with birth demographics and clinical outcomes.

Tijen Karsli, Diana Strickland, Jeffrey Livingston, Qiang Wu, Maroun J Mhanna, Prem S Shekhawat,

<h4>Objective</h4>Assessment of adrenal function in a sick neonate remains a challenge in spite of major advances in neonatal care. We used 2D ultrasound of adrenal glands to assess maturity of adrenal glands in extremely preterm infants and sick term and near term infants.<h4>Study design</h4>We collected demographics details of 99 mother-infants ... Read more >>

J Matern Fetal Neonatal Med (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2019, 32(3):377-383]

Cited: 1 time

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Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study.

Jennifer G Jetton, Louis J Boohaker, Sidharth K Sethi, Sanjay Wazir, Smriti Rohatgi, Danielle E Soranno, Aftab S Chishti, Robert Woroniecki, Cherry Mammen, Jonathan R Swanson, Shanty Sridhar, Craig S Wong, Juan C Kupferman, Russell L Griffin, David J Askenazi, ,

Background:Single-center studies suggest that neonatal acute kidney injury (AKI) is associated with poor outcomes. However, inferences regarding the association between AKI, mortality, and hospital length of stay are limited due to the small sample size of those studies. In order to determine whether neonatal AKI is independently associated with increased ... Read more >>

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2017, 1(3):184-194]

Cited: 33 times

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Respiratory Muscle Weakness and Extubation Failure in Critically Ill Children.

Maroun J Mhanna, Aparna Roy,

Crit Care Med (Critical care medicine)
[2017, 45(8):1423-1424]

Cited: 1 time

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Respiratory severity score and extubation readiness in very low birth weight infants.

Maroun J Mhanna, Narayan P Iyer, Scott Piraino, Mohit Jain,

The respiratory severity score (RSS) is a byproduct of mean airway pressure (MAP) and fraction of inspired oxygen (FiO2). We sought to determine whether RSS could be used as a screening tool to predict extubation readiness in very low birth weight (VLBW) infants.In a retrospective cohort study, medical records of ... Read more >>

Pediatr Neonatol (Pediatrics and neonatology)
[2017, 58(6):523-528]

Cited: 3 times

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Comparison of different definitions of acute kidney injury in extremely low birth weight infants.

Vikas Chowdhary, Ramya Vajpeyajula, Mohit Jain, Syeda Maqsood, Rupesh Raina, Deepak Kumar, Maroun J Mhanna,

<h4>Background</h4>The definition of acute kidney injury (AKI) has evolved over the years, and three definitions have been adapted including pediatric risk injury failure, loss of kidney function (pRIFLE), Acute Kidney Injury Network (AKIN), and Neonatal Modified Kidney Disease Improving Global Outcomes (KDIGO). We sought to report the prevalence and outcome ... Read more >>

Clin Exp Nephrol (Clinical and experimental nephrology)
[2018, 22(1):117-125]

Cited: 3 times

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Outcome of extremely low birth weight infants with a history of neonatal acute kidney injury.

Syeda Maqsood, Nicholas Fung, Vikas Chowdhary, Rupesh Raina, Maroun J Mhanna,

<h4>Objective</h4>To study the outcome of extremely low birth weight (ELBW) infants with a history of acute kidney injury (AKI).<h4>Method</h4>In a retrospective, case control study, medical records of all ELBW infants admitted to the neonatal intensive care unit (NICU) between Jan 2002 and Dec 2011 were reviewed. Medical records were reviewed ... Read more >>

Pediatr Nephrol (Pediatric nephrology (Berlin, Germany))
[2017, 32(6):1035-1043]

Cited: 6 times

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Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates: Design of a Retrospective Cohort Study.

Jennifer G Jetton, Ronnie Guillet, David J Askenazi, Lynn Dill, Judd Jacobs, Alison L Kent, David T Selewski, Carolyn L Abitbol, Fredrick J Kaskel, Maroun J Mhanna, Namasivayam Ambalavanan, Jennifer R Charlton, ,

<h4>Introduction</h4>Acute kidney injury (AKI) affects ~30% of hospitalized neonates. Critical to advancing our understanding of neonatal AKI is collaborative research among neonatologists and nephrologists. The Neonatal Kidney Collaborative (NKC) is an international, multidisciplinary group dedicated to investigating neonatal AKI. The AWAKEN study (Assessment of Worldwide Acute Kidney injury Epidemiology in ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2016, 4:68]

Cited: 26 times

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Effect of sitting vs standing posture on spirometry in children.

Kumar Swamy, Catherine Isroff, Maroun J Mhanna, Akhilesh K Chouksey,

Ann Allergy Asthma Immunol (Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology)
[2016, 117(1):94-96]

Cited: 1 time

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Pediatric pulmonology year in review 2015: Part 3.

David J Birnkrant, Ozge Yilmaz, Thomas Nicolai, Jane B Black, Maroun J Mhanna, Terry L Noah,

Our journal covers a broad range of research and scholarly topics related to children's respiratory disorders. For updated perspectives on the rapidly expanding knowledge in our field, we will summarize the past year's publications in our major topic areas, as well as selected publications in these areas from the core ... Read more >>

Pediatr Pulmonol (Pediatric pulmonology)
[2016, 51(7):747-753]

Cited: 1 time

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Ventilator-Associated Events in Neonates and Children: A Single Definition for a Heterogeneous Population.

Maroun J Mhanna,

Crit Care Med (Critical care medicine)
[2016, 44(1):233-234]

Cited: 0 times

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