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Author Markus Grabbert

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Discrepancy between German S3 Guideline Recommendations and Daily Urologic Practice in the Management of Nonmuscle Invasive Bladder Cancer: Results of a Binational Survey.

Julian P Struck, Martin J P Hennig, Marie C Hupe, Nadim Moharam, Pia Paffenholz, Tim Nestler, Tanja Frank, Thomas S Worst, Markus Grabbert, Philippe-Fabian Pohlmann, Serkan Dogan, Sebastian L Hofbauer, Charis Kalogirou, Angelika Mattigk, Maximilian P Brandt, Laura-Maria Krabbe, Henning Reis, Franz F Dressler, Mario W Kramer, Johannes Salem,

<h4>Introduction</h4>Guideline recommendations are meant to help minimize morbidity and to improve the care of nonmuscle invasive bladder cancer (NMIBC) patients but studies have suggested an underuse of guideline-recommended care. The aim of this study was to evaluate the level of adherence of German and Austrian urologists to German guideline recommendations.<h4>Methods</h4>A ... Read more >>

Urol Int (Urologia internationalis)
[2021, :1-11]

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Comprehensive analysis of complications after transperineal prostate biopsy without antibiotic prophylaxis: results of a multicenter trial with 30 days' follow-up.

Tobias Kohl, August Sigle, Timur Kuru, Johannes Salem, Hanjo Rolfs, Tobias Kowalke, Rodrigo Suarez-Ibarrola, Jakob Michaelis, Nadine Binder, Cordula A Jilg, Arkadiusz Miernik, Markus T Grabbert, W Schultze-Seemann, Christian Gratzke, Daniel Porres,

<h4>Background</h4>To investigate infectious and non-infectious complications after transperineal prostate biopsy (TPB) without antibiotic prophylaxis in a multicenter cohort. Secondly, to identify whether increasing the number of cores was predictive for the occurrence of complications. Thirdly, to examine the relation between TPB and erectile dysfunction.<h4>Methods</h4>We analyzed a retrospective multicenter cohort of ... Read more >>

Prostate Cancer Prostatic Dis (Prostate cancer and prostatic diseases)
[2021, :]

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Evaluation of the Ginsburg Scheme: Where Is Significant Prostate Cancer Missed?

August Sigle, Cordula A Jilg, Timur H Kuru, Nadine Binder, Jakob Michaelis, Markus Grabbert, Wolfgang Schultze-Seemann, Arkadiusz Miernik, Christian Gratzke, Matthias Benndorf, Rodrigo Suarez-Ibarrola,

<h4>Background</h4>Systematic biopsy (SB) according to the Ginsburg scheme (GBS) is widely used to complement MRI-targeted biopsy (MR-TB) for optimizing the diagnosis of clinically significant prostate cancer (sPCa). Knowledge of the GBS's blind sectors where sPCa is missed is crucial to improve biopsy strategies.<h4>Methods</h4>We analyzed cancer detection rates in 1084 patients ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(10):]

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Pretreatment Risk Stratification for Endoscopic Kidney-sparing Surgery in Upper Tract Urothelial Carcinoma: An International Collaborative Study.

Beat Foerster, Mohammad Abufaraj, Surena F Matin, Mounsif Azizi, Mohit Gupta, Wei-Ming Li, Thomas Seisen, Timothy Clinton, Evanguelos Xylinas, M Carmen Mir, Donald Schweitzer, Andrea Mari, Shoji Kimura, Marco Bandini, Romain Mathieu, Ja H Ku, Gautier Marcq, Georgi Guruli, Markus Grabbert, Anna K Czech, Tim Muilwijk, Armin Pycha, David D'Andrea, Firas G Petros, Philippe E Spiess, Trinity Bivalacqua, Wen-Jeng Wu, Morgan Rouprêt, Laura-Maria Krabbe, Kees Hendricksen, Shin Egawa, Alberto Briganti, Marco Moschini, Vivien Graffeille, Wassim Kassouf, Riccardo Autorino, Axel Heidenreich, Piotr Chlosta, Steven Joniau, Francesco Soria, Phillip M Pierorazio, Shahrokh F Shariat,

<h4>Background</h4>Several groups have proposed features to identify low-risk patients who may benefit from endoscopic kidney-sparing surgery in upper tract urothelial carcinoma (UTUC).<h4>Objective</h4>To evaluate standard risk stratification features, develop an optimal model to identify ≥pT2/N+ stage at radical nephroureterectomy (RNU), and compare it with the existing unvalidated models.<h4>Design, setting, and participants</h4>This ... Read more >>

Eur Urol (European urology)
[2021, 80(4):507-515]

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A 27-Year-Old Primigravida with a Right Renal Cell Carcinoma Removed at 30 Weeks of Gestation by Robot-Assisted Retroperitoneoscopic Partial Nephrectomy.

Moritz Völler, Walid Mahmud, Stefan Vallo, Markus Grabbert, Patricia John, Wael Y Khoder,

BACKGROUND Large renal tumors during pregnancy are rare findings (0.07-0.1%). Current guidelines recommend surgical removal. This surgery should be carefully planned in an interdisciplinary team and involves special risks for mother and fetus. This report describes a case of a 27-year-old primigravida woman with a right renal cell carcinoma involving ... Read more >>

Am J Case Rep (The American journal of case reports)
[2021, 22:e927164]

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Novel Classification for Upper Tract Urothelial Carcinoma to Better Risk-stratify Patients Eligible for Kidney-sparing Strategies: An International Collaborative Study.

Gautier Marcq, Beat Foerster, Mohammad Abufaraj, Surena F Matin, Mounsif Azizi, Mohit Gupta, Wei-Ming Li, Thomas Seisen, Timothy Clinton, Evanguelos Xylinas, M Carmen Mir, Donald Schweitzer, Andrea Mari, Shoji Kimura, Marco Bandini, Romain Mathieu, Ja H Ku, Georgi Guruli, Markus Grabbert, Anna K Czech, Tim Muilwijk, Armin Pycha, David D'Andrea, Firas G Petros, Philippe E Spiess, Trinity Bivalacqua, Wen-Jeng Wu, Morgan Rouprêt, Laura-Maria Krabbe, Kees Hendricksen, Shin Egawa, Alberto Briganti, Marco Moschini, Vivien Graffeille, Riccardo Autorino, Patricia John, Axel Heidenreich, Piotr Chlosta, Steven Joniau, Francesco Soria, Phillip M Pierorazio, Shahrokh F Shariat, Wassim Kassouf,

<h4>Background</h4>The European Association of Urology risk stratification dichotomizes patients with upper tract urothelial carcinoma (UTUC) into two risk categories.<h4>Objective</h4>To evaluate the predictive value of a new classification to better risk stratify patients eligible for kidney-sparing surgery (KSS).<h4>Design, setting, and participants</h4>This was a retrospective study including 1214 patients from 21 centers ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Long-term Clinical Outcomes of Repeat Salvage Lymph Node Dissection for Nodal Recurrence of Prostate Cancer After Radical Prostatectomy: A Case Series.

Markus Grabbert, August Sigle, Larissa Lang, Moritz von Büren, Michael Mix, Constantinos Zamboglou, Christian Gratzke, Wolfgang Schultze-Seemann, Cordula A Jilg,

This case series highlights the role of repeat salvage lymph node dissection (sLND) for nodal-recurrent prostate cancer. We provide a descriptive analysis of ten patients who underwent sLND in a total of 23 surgeries (mean 2.3 sLNDs per patient) and their long-term follow-up (median of 158 mo after radical prostatectomy). ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Re: Intravesical Nadofaragene Firadenovec Gene Therapy for BCG-unresponsive Non-muscle-invasive Bladder Cancer: A Single-arm, Open-label, Repeat-dose Clinical Trial.

Markus Grabbert, Roland Seiler, Christian Gratzke,

Eur Urol (European urology)
[2021, 80(1):114]

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99mTc-labelled PSMA ligand for radio-guided surgery in nodal metastatic prostate cancer: proof of principle.

Michael Mix, Wolfgang Schultze-Seemann, Moritz von Büren, August Sigle, Mohamed A Omrane, Markus T Grabbert, Martin Werner, Christian Gratzke, Philipp T Meyer, Cordula A Jilg,

<h4>Purpose</h4>Intraoperative identification of prostate cancer (PCa) lymph node (LN) metastases (LNM) detected by preoperative PSMA PET/CT may be facilitated by PSMA radio-guided surgery (RGS) with use of a γ-probe. Earlier we demonstrated excellent performance of the <sup>111</sup>In-labelled PSMA ligand DKFZ-617 ([<sup>111</sup>In]In-PSMA-617) in RGS for ex situ distinction of LN vs ... Read more >>

EJNMMI Res (EJNMMI research)
[2021, 11(1):22]

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Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis.

Rouven Hoefflin, Adriana Lazarou, Maria Elena Hess, Meike Reiser, Julius Wehrle, Patrick Metzger, Anna Verena Frey, Heiko Becker, Konrad Aumann, Kai Berner, Martin Boeker, Nico Buettner, Christine Dierks, Jesus Duque-Afonso, Michel Eisenblaetter, Thalia Erbes, Ralph Fritsch, Isabell Xiang Ge, Anna-Lena Geißler, Markus Grabbert, Steffen Heeg, Dieter Henrik Heiland, Simone Hettmer, Gian Kayser, Alexander Keller, Anita Kleiber, Alexandra Kutilina, Leman Mehmed, Frank Meiss, Philipp Poxleitner, Justyna Rawluk, Juri Ruf, Henning Schäfer, Florian Scherer, Khalid Shoumariyeh, Andreas Tzschach, Christoph Peters, Tilman Brummer, Martin Werner, Justus Duyster, Silke Lassmann, Cornelius Miething, Melanie Boerries, Anna L Illert, Nikolas von Bubnoff,

Molecular precision oncology faces two major challenges: first, to identify relevant and actionable molecular variants in a rapidly changing field and second, to provide access to a broad patient population. Here, we report a four-year experience of the Molecular Tumor Board (MTB) of the Comprehensive Cancer Center Freiburg (Germany) including ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(5):]

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Safety and side effects of transperineal prostate biopsy without antibiotic prophylaxis.

August Sigle, Rodrigo Suarez-Ibarrola, Marian Pudimat, Jakob Michaelis, Cordula A Jilg, Arkadiusz Miernik, Markus T Grabbert, Wolfgang Schultze-Seemann, Christian Gratzke, Daniel Schlager,

<h4>Study aims</h4>To investigate safety and side effects of transperineal prostate biopsy without antibiotic prophylaxis. Secondary aim was to identify whether the number of cores influenced the occurrence of complications.<h4>Patients and methods</h4>A cohort of 184 patients undergoing perineal prostate biopsy without antibiotic prophylaxis from 2015 to 2017 was analyzed retrospectively. On ... Read more >>

Urol Oncol (Urologic oncology)
[2021, :]

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Five-Year Results of a Prospective Multicenter Trial: AdVance XP for Postprostatectomy-Incontinence in Patients with Favorable Prognostic Factors.

Jan-Niclas Mumm, Benedikt Klehr, Severin Rodler, Alexander Kretschmer, Theresa Vilsmaier, Thilo Westhofen, Michael Chaloupka, Gerald Bastian Schulz, Christian Gozzi, Peter Rehder, Florian May, Roland Homberg, Christian G Stief, Markus Grabbert, Ricarda M Bauer,

<h4>Objective</h4>The aim of this study was to assess the security, value, and efficacy of the second-generation AdVance male sling XP (Boston Scientific®), after implementation in 2010 with advantageous modifications in the sling structure and needle shape, in a prospective multicenter long-term follow-up study.<h4>Methods</h4>In total, 115 patients were included. Exclusion criteria ... Read more >>

Urol Int (Urologia internationalis)
[2021, 105(5-6):421-427]

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Retrospective Evaluation of the Clinical Values of Minimally Invasive Marsupialization of Symptomatic Giant Renal Cysts.

Wael Y Khoder, Markus Grabbert, August Sigle, Sophie Astheimer, Stefan Vallo, Christian Gratzke,

<b><i>Background:</i></b> To evaluate the indication and benefit of minimally invasive laparoscopic marsupialization (MIS) of symptomatic giant renal cysts. <b><i>Materials and Methods:</i></b> Sixty-four consecutive patients who underwent MIS for large renal cysts (Bosniak I; 4 × 5-16 × 12 cm) by one surgeon were included in the study. Presenting symptoms were renal pain (100%), associated with ... Read more >>

J Laparoendosc Adv Surg Tech A (Journal of laparoendoscopic & advanced surgical techniques. Part A)
[2021, 31(3):279-283]

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Patient Selection in Surgical Centers of Expertise in the Treatment of Patients with Moderate to Severe Male Urinary Stress Incontinence.

Markus Grabbert, Ricarda M Bauer, Tanja Hüsch, Alexander Kretschmer, Ruth Kirschner-Hermanns, Ralf Anding, Bernhard Brehmer, Carsten Maik Naumann, Fabian Queissert, Wael Yaseen Khoder, Christian Gratzke, Torben Hofmann, Axel Haferkamp, Wilhelm A Huebner,

<h4>Objective</h4>To analyze decision-making in patients with male urinary incontinence (SUI) in centers of expertise. The artificial urinary sphincter (AUS) remains the gold standard for male patients with moderate to severe SUI but adjustable male slings are a minimally invasive treatment option with good results, hence without a high level of ... Read more >>

Urol Int (Urologia internationalis)
[2020, 104(11-12):902-907]

Cited: 1 time

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Secondary Sling Implantation after Failure of Primary Surgical Treatment for Male Stress Urinary Incontinence: A Retrospective Study.

Markus Grabbert, Tanja Hüsch, Alexander Kretschmer, Ruth Kirschner-Hermanns, Ralf Anding, Bernhard Brehmer, Carsten Maik Naumann, Fabian Queissert, Hagen Loertzer, Wael Khoder, Christian Gratzke, Torben Hofmann, Wilhelm Huebner, Axel Haferkamp, Ricarda M Bauer,

<h4>Objective</h4>The artificial urinary sphincter (AUS) is the surgical gold standard after previously failed surgical treatment for male urinary stress incontinence. The evidence for a male sling as salvage treatment is poor, but there is a proportion of patients that refuse implantation of an AUS or have a relative contraindication. The ... Read more >>

Urol Int (Urologia internationalis)
[2020, 104(7-8):625-630]

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Retropubic vs transobturator Argus adjustable male sling: Results from a multicenter study.

Hagen Loertzer, Tanja Huesch, Ruth Kirschner-Hermanns, Ralf Anding, Armin Rose, Bernhard Brehmer, Carsten Maik Naumann, Fabian Queissert, Joanne Nyarangi-Dix, Roland Homberg, Markus Grabbert, Torben Hofmann, Tobias Pottek, Wilhelm Hübner, Axel Haferkamp, Ricarda Michaela Bauer, Alexander Kretschmer,

AIMS:To comparatively analyse outcomes after ARGUS classic and ArgusT adjustable male sling implantation in a real-world setting. METHODS:Inclusion criteria encompassed: non-neurogenic, moderate-to-severe stress urinary incontinence (≥2 pads), implantation of an ARGUS classic or ArgusT male sling between 2010 and 2012 in a high-volume center (>150 previous implantations). Functional outcomes were ... Read more >>

Neurourol Urodyn (Neurourology and urodynamics)
[2020, 39(3):987-993]

Cited: 2 times

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Comprehensive analysis of Twitter activity on #Incontinence.

Markus Grabbert, Wael Y Khoder, Christian Gratzke, Pia Paffenholz, Johannes Salem, Ricarda M Bauer,

<h4>Aim</h4>The aim of this study is comprehensive analysis of the Twitter activity on #Incontinence.<h4>Material and methods</h4>The following six functional-urology hashtags on Twitter were analyzed from 2015 to 2018 to gain a comprehensive insight into the topic: #Incontinence, #InterstitialCystitis, #OAB, #FPMRS, #BPH, and #UroBPH. For the Twitter analysis, Symplur Signals was ... Read more >>

Neurourol Urodyn (Neurourology and urodynamics)
[2020, 39(1):440-446]

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Extended follow-up of the AdVance XP male sling in the treatment of male urinary stress incontinence after 48 months: Results of a prospective and multicenter study.

Markus Grabbert, Jan-Niclas Mumm, Benedikt Klehr, Alexander Kretschmer, Peter Gebhartl, Christian Gozzi, Roland Homberg, Florian May, Peter Rehder, Christian G Stief, Ricarda M Bauer,

<h4>Objective</h4>To evaluate the efficacy and safety of the AdVance XP male sling in a midterm follow-up for the treatment of male urinary incontinence in a selected patient cohort.<h4>Materials and methods</h4>In all, 115 patients with postprostatectomy incontinence were prospectively enrolled. A previous endoscopic evaluation of a sufficient coaptive zone in the ... Read more >>

Neurourol Urodyn (Neurourology and urodynamics)
[2019, 38(7):1973-1978]

Cited: 5 times

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Efficacy of the Oestrogen Antagonist Tamoxifen on Sperm Parameters in Patients with Idiopathic Oligoathenoteratozoospermia.

Pia Paffenholz, Sinje Votteler, Sassan Nazari, Tim Nestler, Johannes Salem, Markus Grabbert, Melanie von Brandenstein, Sven H Loosen, Silke Zey, Axel Heidenreich, Jan Herden, Johan Denil,

<h4>Background</h4>The oestrogen antagonist tamoxifen has been suggested as an empiric treatment option for treating idiopathic oligoathenoteratozoospermia (iOAT).<h4>Objectives</h4>To analyse the use of tamoxifen in iOAT.<h4>Method</h4>Fifty-seven men receiving tamoxifen for iOAT were recruited from 2016 to 2017 in a retrospective, single-centre setting. Hormone and semen analysis was performed before and after 3 ... Read more >>

Urol Int (Urologia internationalis)
[2019, 103(1):108-115]

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Predictors of thrombosis in testicular cancer during platinum-based chemotherapy.

Pia Paffenholz, Katharina Grein, Isabel Heidegger, Tim Nestler, Markus Grabbert, Johannes Salem, Martin Hellmich, David Pfister, Axel Heidenreich,

<h4>Purpose</h4>To identify potential risk factors for the development of venous thromboembolic events in testicular cancer patients receiving platinum-based chemotherapy.<h4>Methods</h4>We performed a retrospective analysis including 255 patients with testicular germ cell tumors who received platinum-based chemotherapy from 2003 to 2018 as a multi-center observational cohort study. Patient and tumor characteristics of ... Read more >>

World J Urol (World journal of urology)
[2019, 37(9):1907-1916]

Cited: 2 times

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Long-term functional outcome analysis in a large cohort of patients after radical prostatectomy.

Markus Grabbert, Alexander Buchner, Christopher Butler-Ransohoff, Alexander Kretschmer, Christian G Stief, Ricarda M Bauer,

<h4>Introduction</h4>Goal of the study was an analysis of functional outcomes after radical prostatectomy (RP) in a large cohort of patients.<h4>Methods</h4>Functional outcomes were assessed with the ICIQ-SF questionnaire and daily pad-usage for the evaluation of stress urinary incontinence (SUI) as well as with the IIEF-5 score for the evaluation of erectile ... Read more >>

Neurourol Urodyn (Neurourology and urodynamics)
[2018, 37(7):2263-2270]

Cited: 3 times

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[Reconstructive surgery of ureteral stricture disease].

Axel Heidenreich, Markus Grabbert, Tobias Kohl, David Pfister,

Aktuelle Urol (Aktuelle Urologie)
[2017, 48(6):550-560]

Cited: 1 time

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[Male urinary incontinence - causes and therapeutic approaches for male stress incontinence].

Markus Tobias Grabbert, Alexander Kretschmer, Christian Stief, Ricarda Bauer,

MMW Fortschr Med (MMW Fortschritte der Medizin)
[2017, 159(19):52-56]

Cited: 1 time

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Registry of implants for the reconstruction of pelvic floor in males and females: A feasibility case series.

Dimitri Barski, Holger Gerullis, Thorsten Ecke, Jennifer Kranz, Laila Schneidewind, Nadine Leistner, Fabian Queissert, Sandra Mühlstädt, Markus Grabbert, Rana Tahbaz, Alexandre Egon Pelzer, Ralf Joukhadar, Uwe Klinge, Mihaly Boros, Werner Bader, Gert Naumann, Frank Puppe, Thomas Otto,

<h4>Introduction</h4>Most aspects of implant-assisted reconstruction of pelvic floor in males and females are under debate and the research is not standardized. Registries are supposed to shed light to the indications, surgical techniques and material properties and to establish a standardized evaluation.<h4>Methods</h4>A working group was formed to create an online platform ... Read more >>

Int J Surg (International journal of surgery (London, England))
[2017, 42:27-33]

Cited: 1 time

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Follow-up of high-risk bladder cancer-Is it safe to perform fluorescence endoscopy multiple times in the same patient?

Maria Apfelbeck, Tobias Grimm, Alexander Kretschmer, Alexander Buchner, Birte-Swantje Schneevoigt, Friedrich Jokisch, Markus Grabbert, Gerald Schulz, Christian G Stief, Alexander Karl,

<h4>Purpose</h4>As the use of fluorescence endoscopy is recommended today by different guidelines during the follow-up of high-grade non-muscle-invasive bladder cancer, the aim of this study is to analyze whether the multiple use of hexylaminolevulinate (HAL) for TUR-BT can be performed safely within the same patient over a time interval.<h4>Methods</h4>Data of ... Read more >>

Urol Oncol (Urologic oncology)
[2017, 35(10):602.e19-602.e23]

Cited: 1 time

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