Full Text Journal Articles by
Author Mark R Helmers

Advertisement

Find full text journal articles








Organ allocation and procurement in cardiac transplantation.

Peter J Altshuler, Mark R Helmers, Pavan Atluri,

<h4>Purpose of review</h4>There is a critical shortage of organs in cardiac transplantation. Recent advancements in both organ allocation and donor utilization have intended to address this shortage and optimally allocate allografts. This review evaluates several important aspects of recipient and donor management. For recipients, the focus is placed on the ... Read more >>

Curr Opin Organ Transplant (Current opinion in organ transplantation)
[2021, 26(3):282-289]

Cited: 0 times

View full text PDF listing >>



Wisdom from Past Presidents of the Society of Thoracic Surgeons.

Jason J Han, Jarvis C Mays, Amit Iyengar, Jessica G Y Luc, William L Patrick, Mark R Helmers, Benjamin Smood, John J Kelly, Matthew L Williams, Wilson Y Szeto, Marisa Cevasco,

The Society of Thoracic Surgeons (STS) is a highly impactful professional organization in cardiothoracic surgery and an important network of mentors for trainees. Annually, STS presidents deliver an address encapsulating their professional experiences, lessons learned, and future vision for the field. We sought to summarize these lessons into salient points ... Read more >>

Ann Thorac Surg (The Annals of thoracic surgery)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Therapeutic Efficacy of Cryopreserved, Allogeneic Extracellular Vesicles for Treatment of Acute Myocardial Infarction.

Jennifer J Chung, Samuel T Kim, Samir Zaman, Mark R Helmers, Maria F Arisi, Elizabeth C Li, Zoe Tran, Carol W Chen, Peter Altshuler, Minna Chen, Jason A Burdick, Pavan Atluri,

Extracellular vesicles (EV) that are derived from endothelial progenitor cells (EPC) have been determined to be a novel therapy for acute myocardial infarction, with a promise for immediate "off-the-shelf" delivery. Early experience suggests delivery of EVs from allogeneic sources is safe. Yet, clinical translation of this therapy requires assurances of ... Read more >>

Int Heart J (International heart journal)
[2021, 62(2):381-389]

Cited: 0 times

View full text PDF listing >>



Characteristics and Attitudes of Aspiring Cardiothoracic Surgeons: A Survey Study.

Jason J Han, Jarvis C Mays, Amrita Sukhavasi, William L Patrick, Mark R Helmers, Amit Iyengar, Benjamin Smood, John J Kelly, Matthew L Williams, Wilson Y Szeto, Marisa Cevasco,

<h4>Background</h4>Although recruiting highly qualified, diverse applicants into cardiothoracic surgery (CTS) remains a national priority, their characteristics remain unknown. This study aims to better describe the current and future applicants in CTS.<h4>Methods</h4>Aspiring CT surgeons - students interested in matriculating in a North American training program - were voluntarily enrolled in the ... Read more >>

Ann Thorac Surg (The Annals of thoracic surgery)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Permanent pacemaker implantation following mitral valve surgery: a retrospective cohort study of risk factors and long-term outcomes.

Mark R Helmers, Max Shin, Amit Iyengar, Gabriel R Arguelles, Jarvis Mays, Jason J Han, William Patrick, Peter Altshuler, W Clark Hargrove, Pavan Atluri,

<h4>Objectives</h4>Conduction disturbances requiring permanent pacemaker (PPM) implantation remain a complication following valvular surgery. PPMs confer the risk of infection, tricuspid valve regurgitation and pacing-induced cardiomyopathy. Literature examining PPM placement in mitral valve surgery (MVS) is limited.<h4>Methods</h4>Our institutional mitral valve (MV) database was retrospectively reviewed for adult patients undergoing surgery from ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Relationship of Cardiopulmonary Bypass Times and Outcomes in Minimally Invasive Mitral Valve Surgery.

Mark R Helmers, Samuel T Kim, Pavan Atluri,

Ann Thorac Surg (The Annals of thoracic surgery)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Commentary: Surgery of hypertrophic cardiomyopathy: Focus really does matter.

Jason J Han, Mark R Helmers, Pavan Atluri,

J Thorac Cardiovasc Surg (The Journal of thoracic and cardiovascular surgery)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Mitral Valve Surgery in Pulmonary Hypertension Patients: Is Minimally Invasive Surgery Safe?

Mark R Helmers, Samuel T Kim, Peter Altshuler, Jason J Han, Amit Iyengar, John Kelly, Benjamin Smood, W Clark Hargrove, Pavan Atluri,

<h4>Background</h4>Compared with conventional full sternotomy (FS) approaches, minimally invasive mitral valve surgery (MIMVS) offers improved cosmesis, decreased pain and bleeding, and faster recovery without compromising repair or survival rates. However, little is known about outcomes in patients with pulmonary hypertension (PH), an independent risk factor for morbidity and mortality.<h4>Methods</h4>Retrospective review ... Read more >>

Ann Thorac Surg (The Annals of thoracic surgery)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Association Among Surgeon Experience, Patient Risk, and Outcomes in Coronary Artery Bypass Grafting.

Jason J Han, Markian M Bojko, Matthew M Duda, Amit Iyengar, John J Kelly, William L Patrick, Mark R Helmers, Pavan Atluri,

<h4>Background</h4>There is an association between surgeon experience and outcomes after cardiac surgery. However, this association is not well studied in the context of patient risk. The purpose of this single-center, retrospective, observational study was to describe how surgeon experience relates to patient risk in isolated coronary artery bypass grafting (CABG) ... Read more >>

Ann Thorac Surg (The Annals of thoracic surgery)
[2021, 111(1):86-93]

Cited: 0 times

View full text PDF listing >>



Commentary: Calpains: Another piece of the cardiac fibrosis puzzle.

Mark R Helmers, Pavan Atluri,

J Thorac Cardiovasc Surg (The Journal of thoracic and cardiovascular surgery)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Targetable cellular signaling events mediate vascular pathology in vascular Ehlers-Danlos syndrome.

Caitlin J Bowen, Juan Francisco Calderón Giadrosic, Zachary Burger, Graham Rykiel, Elaine C Davis, Mark R Helmers, Kelly Benke, Elena Gallo MacFarlane, Harry C Dietz,

Vascular Ehlers-Danlos syndrome (vEDS) is an autosomal-dominant connective tissue disorder caused by heterozygous mutations in the COL3A1 gene, which encodes the pro-α 1 chain of collagen III. Loss of structural integrity of the extracellular matrix is believed to drive the signs and symptoms of this condition, including spontaneous arterial dissection ... Read more >>

J Clin Invest (The Journal of clinical investigation)
[2020, 130(2):686-698]

Cited: 6 times

View full text PDF listing >>



Commentary: One and done: The case for single-dose del Nido cardioplegia.

Mark R Helmers, Pavan Atluri,

J Thorac Cardiovasc Surg (The Journal of thoracic and cardiovascular surgery)
[2020, 160(5):1203-1204]

Cited: 0 times

View full text PDF listing >>



Redo mitral valve surgery following prior mitral valve repair.

Arman Kilic, Mark R Helmers, Jason J Han, Rahul Kanade, Michael A Acker, Walter Clark Hargrove, Pavan Atluri,

BACKGROUND:The optimal treatment strategy following a failed mitral valve repair remains unclear. This study evaluated early and long-term outcomes of redo mitral valve repair (MVr) and replacement (MVR) after prior mitral valve repair. METHODS:Patients undergoing redo mitral valve surgery after prior mitral valve repair at a single institution between 2002 ... Read more >>

J Card Surg (Journal of cardiac surgery)
[2018, 33(12):772-777]

Cited: 1 time

View full text PDF listing >>



Capping off ventricular assist.

Mark R Helmers, Pavan Atluri,

J Thorac Cardiovasc Surg (The Journal of thoracic and cardiovascular surgery)
[2019, 157(2):e39-e40]

Cited: 0 times

View full text PDF listing >>



Response to: Total arch replacement for repair of porcelain aorta.

Mark R Helmers, Pavan Atluri,

J Thorac Cardiovasc Surg (The Journal of thoracic and cardiovascular surgery)
[2018, 155(2):530]

Cited: 0 times

View full text PDF listing >>



Robotic versus laparoscopic radical nephrectomy: comparative analysis and cost considerations.

Mark R Helmers, Mark W Ball, Michael A Gorin, Phillip M Pierorazio, Mohamad E Allaf,

<h4>Introduction</h4>Robotic-assisted laparoscopic radical nephrectomy (RRN) is an increasing utilized alternative to laparoscopic radical nephrectomy (LRN); however, there is a little data on comparative effectiveness and cost of these procedures. We analyzed perioperative outcomes and hospital charge difference among patients undergoing laparoscopic radical nephrectomy (LRN) and robotic radical nephrectomy (RRN).<h4>Materials and ... Read more >>

Can J Urol (The Canadian journal of urology)
[2016, 23(5):8435-8440]

Cited: 6 times

View full text PDF listing >>



Mapping the BH3 Binding Interface of Bcl-xL, Bcl-2, and Mcl-1 Using Split-Luciferase Reassembly.

Sean T Campbell, Kevin J Carlson, Carl J Buchholz, Mark R Helmers, Indraneel Ghosh,

The recognition of helical BH3 domains by Bcl-2 homology (BH) receptors plays a central role in apoptosis. The residues that determine specificity or promiscuity in this interactome are difficult to predict from structural and computational data. Using a cell free split-luciferase system, we have generated a 276 pairwise interaction map ... Read more >>

Biochemistry (Biochemistry)
[2015, 54(16):2632-2643]

Cited: 1 time

View full text PDF listing >>



Profiling small molecule inhibitors against helix-receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2.

Jason R Porter, Mark R Helmers, Ping Wang, Jennifer L Furman, Stephen T Joy, Paramjit S Arora, Indraneel Ghosh,

We validate a practical methodology for the rapid profiling of small molecule inhibitors of protein-protein interactions. We find that a well known BH3 family inhibitor can potently inhibit the p53/hDM2 interaction. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2010, 46(42):8020-8022]

Cited: 3 times

View full text PDF listing >>





Advertisement

Disclaimer
0.9727 s