Full Text Journal Articles by
Author Mark E Mikkelsen

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Patient and Family Engagement in Critical Illness: Erratum.

Cheryl Misak, Margaret Herridge, E Wesley Ely, Alison Clay, Mark E Mikkelsen,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1195]

Cited: 0 times

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Transitions of Care After Critical Illness-Challenges to Recovery and Adaptive Problem Solving.

Kimberley J Haines, Elizabeth Hibbert, Nina Leggett, Leanne M Boehm, Tarli Hall, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Pamela Mactavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Theodore J Iwashyna, Mark E Mikkelsen, Joanne McPeake, Carla M Sevin, ,

<h4>Objectives</h4>Investigate the challenges experienced by survivors of critical illness and their caregivers across the transitions of care from intensive care to community, and the potential problem-solving strategies used to navigate these challenges.<h4>Design</h4>Qualitative design-data generation via interviews and data analysis via the framework analysis method.<h4>Setting</h4>Patients and caregivers from three continents, identified ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1923-1931]

Cited: 0 times

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Functional outcomes following critical illness: epidemiology, current management strategies and the future priorities.

Joanne McPeake, Carla M Sevin, Mark E Mikkelsen,

<h4>Purpose of review</h4>Intensive care unit (ICU) survivorship has gained significant attention over the course of the COVID-19 pandemic. In this review, we summarize the contemporary literature in relation to the epidemiology and management of post-ICU problems.<h4>Recent findings</h4>Survivors of critical illness can have complex physical, social, emotional and cognitive needs in ... Read more >>

Curr Opin Crit Care (Current opinion in critical care)
[2021, 27(5):506-512]

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Critical Care Clinician Wellness during the COVID-19 Pandemic: A Longitudinal Analysis.

Meeta Prasad Kerlin, Jasmine A Silvestri, Tamar Klaiman, Jacob T Gutsche, Juliane Jablonski, Mark E Mikkelsen,

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2021, :]

Cited: 0 times

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Consensus methodology for the development of postacute sequelae of SARS-CoV-2 guidance statements.

Jason H Maley, Sarah Sampsel, Benjamin A Abramoff, Eric Herman, Kavitha V Neerukonda, Mark E Mikkelsen,

PM R (PM & R : the journal of injury, function, and rehabilitation)
[2021, 13(9):1021-1026]

Cited: 2 times

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Patient and Family Engagement in Critical Illness.

Cheryl Misak, Margaret Herridge, E Wesley Ely, Alison Clay, Mark E Mikkelsen,

Crit Care Med (Critical care medicine)
[2021, 49(9):1389-1401]

Cited: 0 times

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Implementing nudges to promote utilization of low tidal volume ventilation (INPUT): a stepped-wedge, hybrid type III trial of strategies to improve evidence-based mechanical ventilation management.

Meeta Prasad Kerlin, Dylan Small, Barry D Fuchs, Mark E Mikkelsen, Wei Wang, Teresa Tran, Stefania Scott, Aerielle Belk, Jasmine A Silvestri, Tamar Klaiman, Scott D Halpern, Rinad S Beidas,

<h4>Background</h4>Behavioral economic insights have yielded strategies to overcome implementation barriers. For example, default strategies and accountable justification strategies have improved adherence to best practices in clinical settings. Embedding such strategies in the electronic health record (EHR) holds promise for simple and scalable approaches to facilitating implementation. A proven-effective but under-utilized ... Read more >>

Implement Sci (Implementation science : IS)
[2021, 16(1):78]

Cited: 0 times

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Adherence to Lung Protective Ventilation in Patients With Coronavirus Disease 2019.

Elizabeth Levy, Stefania Scott, Teresa Tran, Wei Wang, Mark E Mikkelsen, Barry D Fuchs, Meeta Prasad Kerlin,

Prior studies have demonstrated suboptimal adherence to lung protective ventilation among patients with acute respiratory distress syndrome. A common barrier to providing this evidence-based practice is diagnostic uncertainty. We sought to test the hypothesis that patients with acute respiratory distress syndrome due to coronavirus disease 2019, in whom acute respiratory ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(8):e0512]

Cited: 0 times

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The relationship between vitamin C or thiamine levels and outcomes for severe sepsis patients admitted to the ICU.

Nandan Prasad, Anne V Grossestreuer, Nuala J Meyer, Sarah M Perman, Mark E Mikkelsen, Judd Hollander, David F Gaieski,

Preliminary data have produced conflicting results regarding whether initial vitamin C levels in patients with severe sepsis correlate with mortality outcomes. We hypothesized that low plasma ascorbic acid or thiamine levels in severe sepsis patients admitted from the Emergency Department (ED) to the Intensive Care Unit (ICU) would be associated ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):15114]

Cited: 0 times

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Optimizing Critical Illness Recovery: Perspectives and Solutions From the Caregivers of ICU Survivors.

Carla M Sevin, Leanne M Boehm, Elizabeth Hibbert, Anthony J Bastin, James C Jackson, Joel Meyer, Tara Quasim, Rita N Bakhru, Ashley Montgomery-Yates, Andrew Slack, Mary Still, Giora Netzer, Mark E Mikkelsen, Theodore J Iwashyna, Kimberley J Haines, Joanne McPeake,

<h4>Objectives</h4>To understand the unmet needs of caregivers of ICU survivors, how they accessed support post ICU, and the key components of beneficial ICU recovery support systems as identified from a caregiver perspective.<h4>Design</h4>International, qualitative study.<h4>Subjects</h4>We conducted 20 semistructured interviews with a diverse group of caregivers in the United States, the United ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(5):e0420]

Cited: 1 time

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Functional Outcomes, Goals, and Goal Attainment Amongst Chronically Critically Ill Long-Term Acute Care Hospital Patients.

Randy Dubin, Joshua M Veith, Michael A Grippi, Joanne McPeake, Michael O Harhay, Mark E Mikkelsen,

<h4>Rationale</h4>Chronically critically ill patients admitted to a long-term acute care hospital (LTACH) setting are a vulnerable population of intensive care unit survivors. Little is known of the goals and functional outcomes achieved by patients after rehabilitation in the LTACH setting.<h4>Objectives</h4>We sought to examine patient goals and functional outcomes, including swallowing ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2021, :]

Cited: 0 times

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The Intersection of Health and Critical Illness: Preservation and Restoration.

Jason H Maley, Mark E Mikkelsen,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, 203(12):1451-1453]

Cited: 0 times

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Benefits of Peer Support for Intensive Care Unit Survivors: Sharing Experiences, Care Debriefing, and Altruism.

Joanne McPeake, Theodore J Iwashyna, Leanne M Boehm, Elizabeth Hibbert, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Joel Meyer, Ashley Montgomery-Yates, Mark E Mikkelsen, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Tara Quasim, Carla M Sevin, Kimberley J Haines,

<h4>Background</h4>After critical illness, patients are often left with impairments in physical, social, emotional, and cognitive functioning. Peer support interventions have been implemented internationally to ameliorate these issues.<h4>Objective</h4>To explore what patients believed to be the key mechanisms of effectiveness of peer support programs implemented during critical care recovery.<h4>Methods</h4>In a secondary analysis ... Read more >>

Am J Crit Care (American journal of critical care : an official publication, American Association of Critical-Care Nurses)
[2021, 30(2):145-149]

Cited: 2 times

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Establishing a Peer Support Program for Survivors of COVID-19: A Report From the Critical and Acute Illness Recovery Organization.

Aluko A Hope, Andrea Annie Johnson, Joanne McPeake, Hali Felt, Carla M Sevin, Mark E Mikkelsen, Theodore J Iwashyna, Caroline Lassen-Greene, Kimberley J Haines, Sachin Agarwal, Rita N Bakhru, Leanne M Boehm, Brad W Butcher, Kelly Drumright, Tammy L Eaton, Elizabeth Hibbert, Karen Sara Hoehn, David Hornstein, Heather Imperato-Shedden, James C Jackson, Janet A Kloos, Anna Lewis, Joel Meyer, Ashley Montgomery-Yates, Veronica Rojas, Christa Schorr, Dorothy Wade, Cydni Williams,

Am J Crit Care (American journal of critical care : an official publication, American Association of Critical-Care Nurses)
[2021, :e1-e5]

Cited: 0 times

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Characteristics, Outcomes, and Trends of Patients With COVID-19-Related Critical Illness at a Learning Health System in the United States.

George L Anesi, Juliane Jablonski, Michael O Harhay, Joshua H Atkins, Jasmeet Bajaj, Cameron Baston, Patrick J Brennan, Christina L Candeloro, Lauren M Catalano, Maurizio F Cereda, John M Chandler, Jason D Christie, Tara Collins, Katherine R Courtright, Barry D Fuchs, Emily Gordon, John C Greenwood, Steven Gudowski, Asaf Hanish, C William Hanson, Monica Heuer, Paul Kinniry, Zev Noah Kornfield, Gregory B Kruse, Meghan Lane-Fall, Niels D Martin, Mark E Mikkelsen, Dan Negoianu, Jose L Pascual, Maulik B Patel, Steven C Pugliese, Zaffer A Qasim, John P Reilly, John Salmon, William D Schweickert, Michael J Scott, Michael G S Shashaty, Corinna P Sicoutris, John K Wang, Wei Wang, Arshad A Wani, Brian J Anderson, Jacob T Gutsche,

<h4>Background</h4>The coronavirus disease 2019 (COVID-19) pandemic continues to surge in the United States and globally.<h4>Objective</h4>To describe the epidemiology of COVID-19-related critical illness, including trends in outcomes and care delivery.<h4>Design</h4>Single-health system, multihospital retrospective cohort study.<h4>Setting</h4>5 hospitals within the University of Pennsylvania Health System.<h4>Patients</h4>Adults with COVID-19-related critical illness who were admitted to ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2021, 174(5):613-621]

Cited: 15 times

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The A2F Bundle: Quantity and Quality Matter.

Mark E Mikkelsen, John W Devlin,

Crit Care Med (Critical care medicine)
[2021, 49(2):380-382]

Cited: 0 times

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Prediction Models for Physical, Cognitive, and Mental Health Impairments After Critical Illness: A Systematic Review and Critical Appraisal.

Kimberley J Haines, Elizabeth Hibbert, Joanne McPeake, Brian J Anderson, Oscar Joseph Bienvenu, Adair Andrews, Nathan E Brummel, Lauren E Ferrante, Ramona O Hopkins, Catherine L Hough, James Jackson, Mark E Mikkelsen, Nina Leggett, Ashley Montgomery-Yates, Dale M Needham, Carla M Sevin, Becky Skidmore, Mary Still, Maarten van Smeden, Gary S Collins, Michael O Harhay,

<h4>Objectives</h4>Improved ability to predict impairments after critical illness could guide clinical decision-making, inform trial enrollment, and facilitate comprehensive patient recovery. A systematic review of the literature was conducted to investigate whether physical, cognitive, and mental health impairments could be predicted in adult survivors of critical illness.<h4>Data sources</h4>A systematic search of ... Read more >>

Crit Care Med (Critical care medicine)
[2020, 48(12):1871-1880]

Cited: 5 times

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The sensitivity of qSOFA calculated at triage and during emergency department treatment to rapidly identify sepsis patients.

Sarah M Perman, Mark E Mikkelsen, Munish Goyal, Adit Ginde, Abhishek Bhardwaj, Byron Drumheller, S Cham Sante, Anish K Agarwal, David F Gaieski,

The quick sequential organ failure assessment (qSOFA) score has been proposed as a means to rapidly identify adult patients with suspected infection, in pre-hospital, Emergency Department (ED), or general hospital ward locations, who are in a high-risk category with increased likelihood of "poor outcomes:" a greater than 10% chance of dying ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):20395]

Cited: 0 times

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Benchmarking Critical Care Well-Being: Before and After the Coronavirus Disease 2019 Pandemic.

Sofia Gomez, Brian J Anderson, Hyunmin Yu, Jacob Gutsche, Juliane Jablonski, Niels Martin, Meeta Prasad Kerlin, Mark E Mikkelsen,

<h4>Objectives</h4>Examine well-being, measured as burnout and professional fulfillment, across critical care healthcare professionals, ICUs, and hospitals within a health system; examine the impact of the coronavirus disease 2019 pandemic.<h4>Design</h4>To complement a longitudinal survey administered to medical critical care physicians at the end of an ICU rotation, which began in May ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(10):e0233]

Cited: 3 times

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An International Study Exploring the Experience of Survivors of Critical Illness as Volunteers Within ICU Recovery Services.

Carly Robinson, Elizabeth Hibbert, Anthony J Bastin, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Mark E Mikkelsen, Theodore J Iwashyna, Kimberley J Haines, Carla M Sevin, Joanne McPeake, Leanne M Boehm,

Many clinicians have implemented follow-up and aftercare to support patients following ICU. Some of this care is supported and facilitated by peer volunteers. There is limited contemporary work that has explicitly explored volunteer roles within ICU recovery services or the experience of volunteers undertaking these roles. We sought to explore ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(11):e0273]

Cited: 0 times

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Early Forecasting of Posttraumatic Stress Disorder Symptoms After Critical Illness: Partly Cloudy But Clearing.

Heather M Derry, Mark E Mikkelsen,

Crit Care Med (Critical care medicine)
[2020, 48(11):1694-1696]

Cited: 0 times

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Society of Critical Care Medicine's International Consensus Conference on Prediction and Identification of Long-Term Impairments After Critical Illness.

Mark E Mikkelsen, Mary Still, Brian J Anderson, O Joseph Bienvenu, Martin B Brodsky, Nathan Brummel, Brad Butcher, Alison S Clay, Hali Felt, Lauren E Ferrante, Kimberley J Haines, Michael O Harhay, Aluko A Hope, Ramona O Hopkins, Megan Hosey, Catherine Terri L Hough, James C Jackson, Annie Johnson, Babar Khan, Nazir I Lone, Pamela MacTavish, Joanne McPeake, Ashley Montgomery-Yates, Dale M Needham, Giora Netzer, Christa Schorr, Becky Skidmore, Joanna L Stollings, Reba Umberger, Adair Andrews, Theodore J Iwashyna, Carla M Sevin,

<h4>Background</h4>After critical illness, new or worsening impairments in physical, cognitive, and/or mental health function are common among patients who have survived. Who should be screened for long-term impairments, what tools to use, and when remain unclear.<h4>Objectives</h4>Provide pragmatic recommendations to clinicians caring for adult survivors of critical illness related to screening ... Read more >>

Crit Care Med (Critical care medicine)
[2020, 48(11):1670-1679]

Cited: 16 times

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Hospital Readmission and Post-Acute Care Use After Intensive Care Unit Admissions: New ICU Quality Metrics?

Christopher F Chesley, Michael O Harhay, Dylan S Small, Asaf Hanish, Hallie C Prescott, Mark E Mikkelsen,

<h4>Objective</h4>Care coordination is a national priority. Post-acute care use and hospital readmission appear to be common after critical illness. It is unknown whether specialty critical care units have different readmission rates and what these trends have been over time.<h4>Methods</h4>In this retrospective cohort study, a cohort of 53,539 medical/surgical patients who ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2020, :885066620956633]

Cited: 0 times

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Locally Informed Simulation to Predict Hospital Capacity Needs During the COVID-19 Pandemic.

Gary E Weissman, Andrew Crane-Droesch, Corey Chivers, Mark E Mikkelsen, Scott D Halpern,

Ann Intern Med (Annals of internal medicine)
[2020, 173(8):680-681]

Cited: 6 times

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Extracorporeal Membrane Oxygenation During the Coronavirus Disease 2019 Pandemic.

Mark E Mikkelsen, William Vernick, Jacob Gutsche,

Crit Care Med (Critical care medicine)
[2020, 48(9):1389-1391]

Cited: 1 time

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