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Tympanojugular Paragangliomas: Surgical Management and Clinicopathological Features

Sampath Chandra Prasad, Carlo Terenzio Paties, Francesca Schiavi, Diana Liberata Esposito, Lavinia Vittoria Lotti, Renato Mariani-Costantini, Mario Sanna,

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Audiological Evaluation of Vestibular Schwannoma Patients with Normal Hearing.

Nervana Salem, Ahmed Galal, Valentina Mastronardi, Mohamed Talaat, Ossama Sobhy, Mario Sanna,

OBJECTIVE:To evaluate the audiological aspects of vestibular schwannoma (VS) patients with normal hearing. STUDY DESIGN:Retrospective study. SETTING:Quaternary referral center for skull base pathologies. PATIENTS:The records on 4,000 patients who had been diagnosed with VS between 1986 and December 2017 were retrospectively reviewed. The patients included in the study were the ... Read more >>

Audiol. Neurootol. (Audiology & neuro-otology)
[2019, 24(3):117-126]

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Carotid Body and Vagal Paragangliomas: Epidemiology, Genetics, Clinicopathological Features, Imaging, and Surgical Management

Sampath Chandra Prasad, Carlo Terenzio Paties, Mattia Russel Pantalone, Renato Mariani-Costantini, Mario Sanna,

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Is Middle Fossa Approach Still Indicated for Cochlear Implantation or Should Be Replaced With Subtotal Petrosectomy?

Gianluca Piras, Mario Sanna,

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2019, 40(5):694-695]

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Are Ouctomes of Radiosurgery for Tympanojugular Paraganglioma Overestimated?

Gianluca Piras, Renato Mariani-Costantini, Mario Sanna,

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2019, 40(5):688-689]

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Proper tumor classification and growth rate are key elements when considering indications and results of radiotherapy for head and neck paragangliomas.

Riccardo Albertini, Renato Mariani-Costantini, Mario Sanna,

Head Neck (Head & neck)
[2019, 41(8):2835-2836]

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Are Ouctomes of Radiosurgery For Tympanojugular Paraganglioma Overestimated?

Gianluca Piras, Renato Mariani-Costantini, Mario Sanna,

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2019, :]

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Is Middle Fossa Approach Still Indicated for Cochlear Implantation or Should Be Replaced with Subtotal Petrosectomy?

Gianluca Piras, Mario Sanna,

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2019, :]

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Update in the classification and the role of intra-arterial stenting in the management of carotid body paragangliomas.

Sampath Chandra Prasad, Melissa Laus, Saeed Al-Ghamdi, Ashish Vashishth, Paolo Piazza, Mario Sanna,

BACKGROUND:To review the Shamblin classification of carotid body paragangliomas (CBPs) and the role of intra-arterial stenting in their surgical management. METHODS:Retrospective case series of 20 patients with 28 CBPs that were surgically resected at our center. Intra-arterial stenting was performed in Shamblin II and II classes. RESULTS:The mean follow-up was ... Read more >>

Head Neck (Head & neck)
[2019, 41(5):1379-1386]

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Facial Nerve Outcomes Following Total Excision of Vestibular Schwannoma by the Enlarged Translabyrinthine Approach.

Manjunath Dandinarasaiah, Sampath Chandra Prasad, Enrico Piccirillo, Ashish Vashishth, Mastronardi Valentina, Golda Grinblat, Corneliu Mircea Codreanu, Mario Sanna,

OBJECTIVE:To study the early and late facial nerve (FN) outcomes in different tumor classes in addition to determining the predictive factors for the same. STUDY DESIGN:A retrospective clinical study. SETTING:A quaternary referral otology and skull base center. PATIENTS AND METHODS:A retrospective study of 1983 cases of vestibular schwannomas (VSs) with ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2019, 40(2):226-235]

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Cholesteatoma of the External Auditory Canal: Review of Staging and Surgical Strategy.

Udayabhanu Hn, Sampath C Prasad, Alessandra Russo, Golda Grinblat, Mario Sanna,

INTRODUCTION:External auditory canal cholesteatomas (EACC) is insidious in nature and rare entity. There are only few case series on EACCs and surgical strategy is not standardized. OBJECTIVES:1) To elucidate etiology of EACC and cardinal features. 2) To suggest a practical staging of EACC. 3) To enumerate surgical management according to ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2018, 39(10):e1026-e1033]

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Decision Making in the Wait-and-Scan Approach for Vestibular Schwannomas: Is There a Price to Pay in Terms of Hearing, Facial Nerve, and Overall Outcomes?

Sampath Chandra Prasad, Uma Patnaik, Golda Grinblat, Annalisa Giannuzzi, Enrico Piccirillo, Abdelkader Taibah, Mario Sanna,

BACKGROUND:The wait-and-scan modality has emerged as an important strategy in the management of vestibular schwannoma (VS) as it has been demonstrated that many tumors grow slowly or do not show any growth over long periods. OBJECTIVE:To analyze long-term outcomes of wait-and-scan in the treatment of patients with VS, discuss the ... Read more >>

Neurosurgery (Neurosurgery)
[2018, 83(5):858-870]

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Surgical Management of Intrinsic Tumors of the Facial Nerve.

Sampath Chandra Prasad, Melissa Laus, Manjunath Dandinarasaiah, Enrico Piccirillo, Alessandra Russo, Abdelkader Taibah, Mario Sanna,

BACKGROUND:Intrinsic tumors of the facial nerve are a rare entity. Dealing with this subset of tumors is challenging both in terms of decision making and surgical intervention. OBJECTIVE:To review the outcomes of surgical management of facial nerve tumors and cable nerve graft interpositioning. METHODS:A retrospective analysis was performed at a ... Read more >>

Neurosurgery (Neurosurgery)
[2018, 83(4):740-752]

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Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells.

Rosalba Florio, Laura De Lellis, Serena Veschi, Fabio Verginelli, Viviana di Giacomo, Marialucia Gallorini, Silvia Perconti, Mario Sanna, Renato Mariani-Costantini, Angelica Natale, Arduino Arduini, Rosa Amoroso, Amelia Cataldi, Alessandro Cama,

Paragangliomas (PGLs) are infiltrating autonomic nervous system tumors that cause important morbidity. At present, surgery is the only effective therapeutic option for this rare tumor. Thus, new agents for PGL treatment should be identified. Using unique PGL cell models established in our laboratory, we evaluated the effect of dichloroacetate (DCA) ... Read more >>

Sci Rep (Scientific reports)
[2018, 8(1):13610]

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Atraumatic Scala Tympani Cochleostomy; Resolution of the Dilemma.

Ahmad Badr, Yousef Shabana, Khaled Mokbel, Ayman Elsharabasy, Mohamed Ghonim, Mario Sanna,

OBJECTIVES:While an accurate placement in cochleostomy is critical to ensure appropriate insertion of the cochlear implant (CI) electrode into the scala tympani (ST), the choice of preferred cochleostomy sites widely varied among experienced surgeons. We present a novel technique for precise yet readily applicable localization of the optimum site for ... Read more >>

J Int Adv Otol (The journal of international advanced otology)
[2018, 14(2):190-196]

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Transcanal Transpromontorial Approach to Vestibular Schwannoma: Are We There Yet?

Sampath Chandra Prasad, Mario Sanna,

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2018, 39(5):661-662]

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Correction to: Paragangliomas arise through an autonomous vasculo-angio-neurogenic program inhibited by imatinib.

Fabio Verginelli, Silvia Perconti, Simone Vespa, Francesca Schiavi, Sampath Chandra Prasad, Paola Lanuti, Alessandro Cama, Lorenzo Tramontana, Diana Liberata Esposito, Simone Guarnieri, Artenca Sheu, Mattia Russel Pantalone, Rosalba Florio, Annalisa Morgano, Cosmo Rossi, Giuseppina Bologna, Marco Marchisio, Andrea D'Argenio, Elisa Taschin, Rosa Visone, Giuseppe Opocher, Angelo Veronese, Carlo T Paties, Vinagolu K Rajasekhar, Cecilia Söderberg-Nauclér, Mario Sanna, Lavinia Vittoria Lotti, Renato Mariani-Costantini,

The given and family names of two co-authors were incorrect in the published article. The correct spelling should read as: Sampath Chandra Prasad and Vinagolu K Rajasekhar. ... Read more >>

Acta Neuropathol. (Acta neuropathologica)
[2018, 135(5):799]

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Temporal Bone Meningo-Encephalic-Herniation: Etiological Categorization and Surgical Strategy.

Golda Grinblat, Manjunath Dandinarasaiah, Sampath Chandra Prasad, Gianluca Piras, Enrico Piccirillo, Andrea Fulcheri, Mario Sanna,

OBJECTIVE:To study the clinical presentation, intraoperative findings and surgical management in meningo-encephalic-herniation (MEH) based on the etiology. STUDY DESIGN:A retrospective clinical study and is a follow-up on the previously published report in 2009. SETTING:A quaternary referral otology and skull base center PATIENTS AND METHODS:: The inclusion criteria were intraoperatively verified ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2018, 39(3):320-332]

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Incomplete and false tract insertions in cochlear implantation: retrospective review of surgical and auditory outcomes.

Ashish Vashishth, Andrea Fulcheri, Maurizio Guida, Antonio Caruso, Mario Sanna,

To evaluate incidence, demographics, surgical, and radiological correlates of incomplete and false tract electrode array insertions during cochlear implantation (CI). To evaluate outcomes in patients with incomplete electrode insertion (IEI).Retrospective analysis.Otology and skull base center.Charts of 18 patients (19 ears) with incomplete or false tract insertions of the electrode array ... Read more >>

Eur Arch Otorhinolaryngol (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery)
[2018, 275(5):1059-1068]

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Cochlear Implantation in Chronic Otitis Media With Cholesteatoma and Open Cavities: Long-term Surgical Outcomes.

Ashish Vashishth, Andrea Fulcheri, Sampath Chandra Prasad, Manjunath Dandinarasaiah, Antonio Caruso, Mario Sanna,

To evaluate the long-term surgical outcomes of cochlear implantation (CI) in chronic otitis media (COM) with cholesteatoma and open cavities using subtotal petrosectomy (STP). To review device explantation (DE) patients and reimplantation considerations.Retrospective review.Otology and skull base center.Charts of 35 patients (36 ears) with COM with cholesteatoma, including open cavities, ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2018, 39(1):45-53]

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Cochlear Implantation in Cochlear Ossification: Retrospective Review of Etiologies, Surgical Considerations, and Auditory Outcomes.

Ashish Vashishth, Andrea Fulcheri, Sampath Chandra Prasad, Margherita Bassi, Gianluca Rossi, Antonio Caruso, Mario Sanna,

1) To review the surgical and auditory outcomes and complications of cochlear implantation in cases with cochlear ossification. 2) To evaluate association between the extent and etiology of ossification to outcomes.Retrospective study.Otology and skull base surgery center.Charts of 40 patients (42 ears) with cochlear ossification undergoing cochlear implantation were reviewed. ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2018, 39(1):17-28]

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The Importance of Using the Modified Fisch Classification and the Determination of the Natural Rate of Growth of Tumor by Wait-and-Scan Approach Before Offering Radiosurgery for Tympanojugular Paragangliomas.

Sampath Chandra Prasad, Mario Sanna,

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2017, 38(10):1550-1551]

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Petrous Apex Cholesterol Granulomas: Outcomes, Complications, and Hearing Results From Surgical and Wait-and-Scan Management.

Golda Grinblat, Ashish Vashishth, Francesco Galetti, Antonio Caruso, Mario Sanna,

1. To analyze the surgical outcomes in the management of petrous apex cholesterol granulomas (PACG) with a brief literature review.2. To evaluate the importance of wait-and-scan management option.Retrospective review.Quaternary referral center for otology and skull base surgery.Charts of 55 patients with at least 12 months of follow-up were analyzed for ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2017, 38(10):e476-e485]

Cited: 1 time

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Cochlear Implantation in Otosclerosis: Surgical and Auditory Outcomes With a Brief on Facial Nerve Stimulation.

Ashish Vashishth, Andrea Fulcheri, Gianluca Rossi, Sampath Chandra Prasad, Antonio Caruso, Mario Sanna,

1) To review the surgical and auditory outcomes in patients of cochlear implantation in otosclerosis. 2) To review complications and postimplantation facial nerve stimulation (FNS). 3) To compare the auditory outcomes between patients displaying cochlear ossification to the nonossified ones.Retrospective study.Quaternary Otology and Skull base surgery center.Charts of 36 patients ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2017, 38(9):e345-e353]

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Rapidly growing cystic vestibular schwannoma with sudden onset facial palsy, ten years after subtotal excision.

Manjunath Dandinarasaiah, Golda Grinblat, Sampath Chandra Prasad, Abdelkader Taibah, Mario Sanna,

An elderly male patient diagnosed with a right-sided cystic vestibular schwannoma (CVS) at our center underwent a translabyrinthine approach with a subtotal excision to preserve the facial nerve (FN). The tumor grew slowly for the first 9 years but in the subsequent 2 years grew rapidly, with the patient developing ... Read more >>

Laryngoscope (The Laryngoscope)
[2018, 128(7):1649-1652]

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