Full Text Journal Articles by
Author Maria Vazquez Roque

Advertisement

Find full text journal articles






Editorial: understanding IBS pathophysiology through "converging channels" of research-authors' reply.

Madhusudan Grover, Antonio Berumen, Stephanie Peters, Ting Wei, Margaret Breen-Lyles, William S Harmsen, Irene Busciglio, Duane Burton, Maria Vazquez Roque, Kenneth R DeVault, Michael Camilleri, Michael Wallace, Surendra Dasari, Helmut Neumann, Lesley A Houghton,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(9):1215-1216]

Cited: 0 times

View full text PDF listing >>



Intestinal chemosensitivity in irritable bowel syndrome associates with small intestinal TRPV channel expression.

Madhusudan Grover, Antonio Berumen, Stephanie Peters, Ting Wei, Margaret Breen-Lyles, William S Harmsen, Irene Busciglio, Duane Burton, Maria Vazquez Roque, Kenneth R DeVault, Michael Camilleri, Michael Wallace, Surendra Dasari, Helmut Neumann, Lesley A Houghton,

<h4>Background</h4>Irritable bowel syndrome (IBS) patients often experience meal-associated symptoms. However, the underlying mechanisms are unclear.<h4>Aim</h4>To determine small intestinal mechanisms of lipid-induced symptoms and rectal hypersensitivity in IBS METHODS: We recruited 26 IBS patients (12 IBS-C, 14 IBS-D) and 15 healthy volunteers (HV). In vivo permeability was assessed using saccharide excretion ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(9):1179-1192]

Cited: 0 times

View full text PDF listing >>



Advertisement

Gastric Emptying Scans: Poor Adherence to National Guidelines.

Journey L Wise, Maria I Vazquez-Roque, Caleb J McKinney, Michael A Zickella, Michael D Crowell, Brian E Lacy,

<h4>Background</h4>Accurately diagnosing gastroparesis relies upon gastric emptying scintigraphy (GES) being performed correctly. Jointly published protocol guidelines have long been available; however, the extent to which practitioners adhere to these guidelines is unknown.<h4>Aims</h4>This study aimed to assess national compliance with established GES protocol guidelines.<h4>Methods</h4>We developed a questionnaire addressing the key protocol ... Read more >>

Dig Dis Sci (Digestive diseases and sciences)
[2021, 66(9):2897-2906]

Cited: 2 times

View full text PDF listing >>



Management of Chronic Abdominal Distension and Bloating.

Brian E Lacy, David Cangemi, Maria Vazquez-Roque,

Abdominal bloating and distension are 2 of the most commonly reported gastrointestinal symptoms. Abdominal bloating is characterized by symptoms of trapped gas, abdominal pressure, and fullness. Abdominal distension is defined as a measurable increase in abdominal girth. These symptoms frequently co-exist, although they can occur separately. Defined by Rome IV ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, 19(2):219-231.e1]

Cited: 1 time

View full text PDF listing >>



Relationship of gastric emptying or accommodation with satiation, satiety, and postprandial symptoms in health.

Houssam Halawi, Michael Camilleri, Andres Acosta, Maria Vazquez-Roque, Ibironke Oduyebo, Duane Burton, Irene Busciglio, Alan R Zinsmeister,

The contributions of gastric emptying (GE) and gastric accommodation (GA) to satiation, satiety, and postprandial symptoms remain unclear. We aimed to evaluate the relationships between GA or GE with satiation, satiety, and postprandial symptoms in healthy overweight or obese volunteers (total <i>n</i> = 285, 73% women, mean BMI 33.5 kg/m<sup>2</sup>): ... Read more >>

Am J Physiol Gastrointest Liver Physiol (American journal of physiology. Gastrointestinal and liver physiology)
[2017, 313(5):G442-G447]

Cited: 14 times

View full text PDF listing >>



Collagenous Gastritis and Helicobacter pylori Infection: A Mere Coincidence?

Daniela G Vinsard, Lady Katherine Mejia Perez, Aziza Nassar, Maria I Vazquez Roque,

A 21-year-old woman presented to our clinic after 7 years of abdominal pain, diarrhea, and iron-deficiency anemia. Initial upper endoscopy revealed severe inflammation and nodularity of the gastric body and active Helicobacter pylori infection. After eradication therapy, esophagogastroduodenoscopy showed gastric atrophy with nodularity resolution. Histopathology revealed scattered plasma cells, eosinophils, ... Read more >>

ACG Case Rep J (ACG case reports journal)
[2017, 4:e69]

Cited: 1 time

View full text PDF listing >>



Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression.

Richard L Wu, Maria I Vazquez-Roque, Paula Carlson, Duane Burton, Madhusudan Grover, Michael Camilleri, Jerrold R Turner,

The mechanisms underlying diarrhea-predominant irritable bowel syndrome (IBS-D) are poorly understood, but increased intestinal permeability is thought to contribute to symptoms. A recent clinical trial of gluten-free diet (GFD) demonstrated symptomatic improvement, relative to gluten-containing diet (GCD), which was associated with reduced intestinal permeability in non-celiac disease IBS-D patients. The ... Read more >>

Lab Invest (Laboratory investigation; a journal of technical methods and pathology)
[2017, 97(1):14-23]

Cited: 21 times

View full text PDF listing >>



Analysis of Biopsies From Duodenal Bulbs of All Endoscopy Patients Increases Detection of Abnormalities but has a Minimal Effect on Diagnosis of Celiac Disease.

Samantha A Stoven, Rok Seon Choung, Alberto Rubio-Tapia, Imad Absah, Dora M Lam-Himlin, Lucinda A Harris, Saowanee Ngamruengphong, Maria I Vazquez Roque, Tsung-Teh Wu, Joseph A Murray,

<h4>Background & aims</h4>In patients with positive results from serologic tests for celiac disease, analysis of tissues samples from the duodenal bulb, in addition to those from other parts of the small bowel, might increase the diagnostic yield. However, biopsies are not routinely collected from the duodenal bulb because of concerns ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2016, 14(11):1582-1588]

Cited: 9 times

View full text PDF listing >>



Effect of alginate on satiation, appetite, gastric function, and selected gut satiety hormones in overweight and obesity.

Suwebatu T Odunsi, María I Vázquez-Roque, Michael Camilleri, Athanasios Papathanasopoulos, Matthew M Clark, Lynne Wodrich, Mary Lempke, Sanna McKinzie, Michael Ryks, Duane Burton, Alan R Zinsmeister,

Lack of control of food intake, excess size, and frequency of meals are critical to the development of obesity. The stomach signals satiation postprandially and may play an important role in control of calorie intake. Sodium alginate (based on brown seaweed Laminaria digitata) is currently marketed as a weight loss ... Read more >>

Obesity (Silver Spring) (Obesity (Silver Spring, Md.))
[2010, 18(8):1579-1584]

Cited: 31 times

View full text PDF listing >>



Nonceliac Gluten Sensitivity.

Maria Vazquez-Roque, Amy S Oxentenko,

Nonceliac gluten sensitivity (NCGS) is the clinical term used to describe gastrointestinal (GI) and/or extraintestinal symptoms associated with gluten ingestion. The prevalence of NCGS is unknown. The condition has clinical features that overlap with those of celiac disease (CD) and wheat allergy (WA). The pathophysiologic process in NCGS is thought ... Read more >>

Mayo Clin Proc (Mayo Clinic proceedings)
[2015, 90(9):1272-1277]

Cited: 8 times

View full text PDF listing >>



Relamorelin Relieves Constipation and Accelerates Colonic Transit in a Phase 2, Placebo-Controlled, Randomized Trial.

Andres Acosta, Michael Camilleri, Gururaj Kolar, Johanna Iturrino, Lawrence A Szarka, Amy Boldingh, Duane Burton, Michael Ryks, Deborah Rhoten, Alan R Zinsmeister, Sharon C Spence, Keith Gottesdiener, Ernest P Bouras, Maria I Vazquez-Roque,

<h4>Background & aims</h4>Ghrelin receptors are located in the colon. Relamorelin is a pentapeptide selective agonist of ghrelin receptor 1a with gastric effects, but its effects in the colon are not known. We aimed to evaluate the effects of relamorelin on bowel movements (BMs) and gastrointestinal and colonic transit (CT) in ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2015, 13(13):2312-9.e1]

Cited: 22 times

View full text PDF listing >>



Epidemiology and management of chronic constipation in elderly patients.

Maria Vazquez Roque, Ernest P Bouras,

Constipation is a common functional gastrointestinal disorder, with prevalence in the general population of approximately 20%. In the elderly population the incidence of constipation is higher compared to the younger population, with elderly females suffering more often from severe constipation. Treatment options for chronic constipation (CC) include stool softeners, fiber ... Read more >>

Clin Interv Aging (Clinical interventions in aging)
[2015, 10:919-930]

Cited: 43 times

View full text PDF listing >>



Association of UCP-3 rs1626521 with obesity and stomach functions in humans.

Andres Acosta, Michael Camilleri, Andrea Shin, Maria I Vazquez-Roque, Johanna Iturrino, Ian R Lanza, K Sreekumaran Nair, Duane Burton, Jessica O'Neill, Deborah Eckert, Paula Carlson, Adrian Vella, Alan R Zinsmeister,

<h4>Objective</h4>To examine the association of gene variants of uncoupling proteins (UCP)-2 and -3 with obesity and gastrointestinal (GI) traits.<h4>Methods</h4>In 255 overweight or obese adults, the associations of gene variants in UCP-2 (-3474, rs659366) and UCP-3 (rs1626521, rs2075577, rs15763) with body weight (BW) and GI traits were studied. Gene variants were ... Read more >>

Obesity (Silver Spring) (Obesity (Silver Spring, Md.))
[2015, 23(4):898-906]

Cited: 5 times

View full text PDF listing >>



Quantitative gastrointestinal and psychological traits associated with obesity and response to weight-loss therapy.

Andres Acosta, Michael Camilleri, Andrea Shin, Maria I Vazquez-Roque, Johanna Iturrino, Duane Burton, Jessica O'Neill, Deborah Eckert, Alan R Zinsmeister,

<h4>Background & aims</h4>Weight loss after pharmacotherapy varies greatly. We aimed to examine associations of quantitative gastrointestinal and psychological traits with obesity, and to validate the ability of these traits to predict responses of obese individuals to pharmacotherapy.<h4>Methods</h4>In a prospective study, we measured gastric emptying of solids and liquids, fasting and ... Read more >>

Gastroenterology (Gastroenterology)
[2015, 148(3):537-546.e4]

Cited: 64 times

View full text PDF listing >>



Imaging the leaky gut.

Michael B Wallace, Maria Vazquez-Roque, Christian Bojarski, Jörg-Dieter Schulzke,

Gastroenterology (Gastroenterology)
[2014, 147(5):952-954]

Cited: 2 times

View full text PDF listing >>



Novel Association of Rectal Evacuation Disorder and Rumination Syndrome: Diagnosis, Co-morbidities and Treatment.

Priya Vijayvargiya, Johanna Iturrino, Michael Camilleri, Andrea Shin, Maria Vazquez-Roque, David A Katzka, Jill R Snuggerud, Richard J Seime,

<h4>Background</h4>Patients with disorders of gastrointestinal function may undergo unnecessary treatment if misdiagnosed as motility disorders.<h4>Objective</h4>To report on clinical features, medical, surgical and psychiatric co-morbidities, and prior treatments of a patient cohort diagnosed concurrently with non-psychogenic rumination syndrome and pelvic floor dysfunction (also termed rectal evacuation disorder).<h4>Methods</h4>From a consecutive series (1994-2013) ... Read more >>

United European Gastroenterol J (United European gastroenterology journal)
[2014, 2(1):38-46]

Cited: 5 times

View full text PDF listing >>



Gastroparesis: from concepts to management.

Ernest P Bouras, Maria I Vazquez Roque, Jaime Aranda-Michel,

While the symptoms of gastroparesis are common, an accurate diagnosis is based on a combination of those symptoms with a documented delay in gastric emptying. Typical symptoms include nausea, vomiting, early satiety, postprandial fullness, bloating, and abdominal discomfort. Patients with gastroparesis face many diagnostic and therapeutic challenges. The most common ... Read more >>

Nutr Clin Pract (Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition)
[2013, 28(4):437-447]

Cited: 4 times

View full text PDF listing >>



Reply: To PMID 23357715.

Maria Vazquez-Roque, Michael Camilleri, Alan R Zinsmeister,

Gastroenterology (Gastroenterology)
[2013, 145(3):694]

Cited: 0 times

View full text PDF listing >>



Linaclotide, novel therapy for the treatment of chronic idiopathic constipation and constipation-predominant irritable bowel syndrome.

Maria I Vazquez-Roque, Ernest P Bouras,

Chronic constipation (CC) and irritable bowel syndrome with constipation (IBS-C) are common gastrointestinal (GI) disorders. Current treatment options, either prescription or nonprescription medications, have limited efficacy in a subset of patients. There is significant demand for more efficacious medications for the treatment of CC and IBS-C. Linaclotide, a secretagogue, has ... Read more >>

Adv Ther (Advances in therapy)
[2013, 30(3):203-211]

Cited: 6 times

View full text PDF listing >>



A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function.

Maria I Vazquez-Roque, Michael Camilleri, Thomas Smyrk, Joseph A Murray, Eric Marietta, Jessica O'Neill, Paula Carlson, Jesse Lamsam, Denise Janzow, Deborah Eckert, Duane Burton, Alan R Zinsmeister,

<h4>Background & aims</h4>Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) could benefit from a gluten-free diet (GFD).<h4>Methods</h4>We performed a randomized controlled 4-week trial of a gluten-containing diet (GCD) or GFD in 45 patients with IBS-D; genotype analysis was performed for HLA-DQ2 and HLA-DQ8. Twenty-two patients were placed on the GCD (11 ... Read more >>

Gastroenterology (Gastroenterology)
[2013, 144(5):903-911.e3]

Cited: 196 times

View full text PDF listing >>



Effect of a glucagon-like peptide 1 analog, ROSE-010, on GI motor functions in female patients with constipation-predominant irritable bowel syndrome.

Michael Camilleri, Maria Vazquez-Roque, Johanna Iturrino, Amy Boldingh, Duane Burton, Sanna McKinzie, Banny S Wong, Archana S Rao, Enda Kenny, Maria Månsson, Alan R Zinsmeister,

The glucagon-like peptide 1 (GLP-1) analog ROSE-010 reduced pain during acute exacerbations of irritable bowel syndrome (IBS). Our objective was to assess effects of ROSE-010 on several gastrointestinal (GI) motor and bowel functions in constipation-predominant IBS (IBS-C). In a single-center, randomized, parallel-group, double-blind, placebo-controlled, dose-response study, we evaluated safety, pharmacodynamics, ... Read more >>

Am J Physiol Gastrointest Liver Physiol (American journal of physiology. Gastrointestinal and liver physiology)
[2012, 303(1):G120-8]

Cited: 23 times

View full text PDF listing >>



Regional colon transit in patients with dys-synergic defaecation or slow transit in patients with constipation.

Sara Nullens, Tyler Nelsen, Michael Camilleri, Duane Burton, Deborah Eckert, Johanna Iturrino, Maria Vazquez-Roque, Alan R Zinsmeister,

<h4>Objective</h4>To differentiate dys-synergic defaecation (DD) from normal function and slow transit constipation (STC).<h4>Methods</h4>The medical records of 1411 patients evaluated by a single gastroenterologist over a 16-year period at a tertiary medical centre were reviewed. DD was characterised by anorectal manometry and balloon expulsion test. There were 390 patients with DD, ... Read more >>

Gut (Gut)
[2012, 61(8):1132-1139]

Cited: 44 times

View full text PDF listing >>



Association of TCF7L2 allelic variations with gastric function, satiation, and GLP-1 levels.

Maria I Vazquez-Roque, Michael Camilleri, Adrian Vella, Paula Carlson, Jeanette Laugen, Alan R Zinsmeister,

<h4>Objective</h4>Genetic variation in transcription factor 7-like 2 (TCF7L2), a regulator of proglucagon processing, is reproducibly associated with type 2 diabetes. GLP-1 alters gastric function and increases satiation.<h4>Hypothesis</h4>Genetic variation in TCF7L2 is associated with satiation, gastric motor function, and GLP-1 concentrations.<h4>Methods</h4>In 62 adults, a single nucleotide polymorphism (SNP) of TCF7L2 (rs7903146) ... Read more >>

Clin Transl Sci (Clinical and translational science)
[2011, 4(3):183-187]

Cited: 10 times

View full text PDF listing >>



Association of bile acid receptor TGR5 variation and transit in health and lower functional gastrointestinal disorders.

M Camilleri, M I Vazquez-Roque, P Carlson, D Burton, B S Wong, A R Zinsmeister,

<h4>Background</h4>The membrane bound bile acid (BA) receptor, TGR5, is located on myenteric, cholinergic and nitrergic neurons in colon and proximal small intestine. Our aim was to assess the association of genetic variation in TGR5 and small bowel transit (SBT) and colonic transit.<h4>Methods</h4>In 230 healthy controls and 414 patients with lower ... Read more >>

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2011, 23(11):995-9, e458]

Cited: 32 times

View full text PDF listing >>



Association of genetic variation in cannabinoid mechanisms and gastric motor functions and satiation in overweight and obesity.

M I Vazquez-Roque, M Camilleri, A Vella, P Carlson, J Laugen, A R Zinsmeister,

<h4>Background</h4>The endocannabinoid system is associated with food intake. We hypothesized that genes regulating cannabinoids are associated with obesity. Genetic variations in fatty acid amide hydroxylase (FAAH) and cannabinoid receptor 1 (CNR1) are associated with satiation and gastric motor function.<h4>Methods</h4>In 62 overweight or obese adults of European ancestry, single nucleotide polymorphisms ... Read more >>

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2011, 23(7):637-e257]

Cited: 6 times

View full text PDF listing >>



Advertisement


Disclaimer

1.2827 s