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Author Maria Letizia Bacchi Reggiani

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Dry Eye Disease and Tear Cytokine Levels-A Meta-Analysis.

Matilde Roda, Ivan Corazza, Maria Letizia Bacchi Reggiani, Marco Pellegrini, Leonardo Taroni, Giuseppe Giannaccare, Piera Versura,

Background-It is recognized that inflammation is an underlying cause of dry eye disease (DED), with cytokine release involved. We systematically reviewed literature with meta-analyses to quantitatively summarize the levels of tear cytokines in DED. Methods-The PubMed, Embase, Web of Science, Ovid, Cochrane, and Scopus databases were reviewed until September 2019, ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(9):]

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Coronary Protection to Prevent Coronary Obstruction During TAVR: A Multicenter International Registry.

Tullio Palmerini, Tarun Chakravarty, Francesco Saia, Antonio G Bruno, Maria-Letizia Bacchi-Reggiani, Cinzia Marrozzini, Chinar Patel, Vivek Patel, Luca Testa, Francesco Bedogni, Marco Ancona, Matteo Montorfano, Alaide Chieffo, Paolo Olivares, Antonio L Bartorelli, Angelo Buscaglia, Italo Porto, Georg Nickenig, Eberhard Grube, Jan-Malte Sinning, Marco De Carlo, Anna Sonia Petronio, Marco Barbanti, Corrado Tamburino, Alessandro Iadanza, Francesco Burzotta, Carlo Trani, Chiara Fraccaro, Giuseppe Tarantini, Tiziana C Aranzulla, Mauro De Benedictis, Paolo Pagnotta, Giulio G Stefanini, Mizuki Miura, Maurizio Taramasso, Jee-Hoon Kang, Hyo-Soo Kim, Pablo Codner, Ran Kornowski, Francesco Pelliccia, Luigi Vignali, Nevio Taglieri, Gabriele Ghetti, Alessandro Leone, Nazzareno Galiè, Raj Makkar,

OBJECTIVES:The aim of this study was to investigate the safety and efficacy of coronary protection by preventive coronary wiring and stenting across the coronary ostia in patients at high risk for coronary obstruction after transcatheter aortic valve replacement (TAVR). BACKGROUND:Coronary obstruction following TAVR is a life-threatening complication with high procedural ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2020, 13(6):739-747]

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Impact of coronary bypass or stenting on mortality and myocardial infarction in stable coronary artery disease.

Nevio Taglieri, Antonio G Bruno, Maria Letizia Bacchi Reggiani, Emanuela C D'Angelo, Gabriele Ghetti, Matteo Bruno, Tullio Palmerini, Claudio Rapezzi, Nazzareno Galiè, Francesco Saia,

BACKGROUND:To assess whether coronary bypass (CABG) or stenting reduce the risk of mortality and myocardial infarction (MI) compared with optimal medical therapy (OMT) in stable coronary artery disease (CAD). METHODS:We performed a systematic review and network meta-analysis of contemporary randomized controlled trials comparing OMT, CABG and different stent types in ... Read more >>

Int. J. Cardiol. (International journal of cardiology)
[2020, 309:63-69]

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Does the Site of Origin of the Microcarcinoma with Respect to the Thyroid Surface Matter? A Multicenter Pathologic and Clinical Study for Risk Stratification.

Giovanni Tallini, Antonio De Leo, Andrea Repaci, Dario de Biase, Maria Letizia Bacchi Reggiani, Doriana Di Nanni, Francesca Ambrosi, Cira Di Gioia, Giorgio Grani, Kerry Jane Rhoden, Erica Solaroli, Fabio Monari, Sebastiano Filetti, Cosimo Durante,

It is unclear whether the site of origin of papillary thyroid microcarcinoma (mPTC) with respect to the thyroid surface has an influence on clinicopathologic parameters. The objectives of the study were to: (i) Accurately measure the mPTC distance from the thyroid surface; (ii) analyze whether this distance correlates with relevant ... Read more >>

Cancers (Basel) (Cancers)
[2020, 12(1):]

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Predictors of survival in malignant aortic tumors.

Andrea Vacirca, Gianluca Faggioli, Rodolfo Pini, Antonio Freyrie, Giuseppe Indelicato, Cecilia Fenelli, Maria Letizia Bacchi Reggiani, Francesco Vasuri, Gianandrea Pasquinelli, Andrea Stella, Mauro Gargiulo,

OBJECTIVE:Malignant aortic tumors (MATs) are exceedingly rare, and a comprehensive review of clinical and therapeutic aspects is lacking in the literature. The aim of this study was to analyze all known cases of MATs and to identify predictors of patients' survival. METHODS:All patients diagnosed with an aortic tumor treated in ... Read more >>

J. Vasc. Surg. (Journal of vascular surgery)
[2020, 71(5):1771-1780]

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Interleukin 28 Polymorphisms and Hepatocellular Carcinoma Development after Direct Acting Antiviral Therapy for Chronic Hepatitis C.

Angelo Simili, Giuseppe Mazzella, Federico Ravaioli, Davide Festi, Maria Letizia Bacchi-Reggiani, Alberto Porro, Franco Bazzoli, Francesco Azzaroli,

BACKGROUND AND AIMS:Cirrhotic patients with hepatitis C virus (HCV) infection remain at risk of developing hepatocellular carcinoma (HCC) even after the sustained virologic response (SVR). We aimed to evaluate whether the IL28 (rs12979860) single nucleotide polymorphism (SNP) may constitute a predisposing genetic factor and to identify the SVR patients at ... Read more >>

J Gastrointestin Liver Dis (Journal of gastrointestinal and liver diseases : JGLD)
[2019, 28(4):449-456]

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Epidemiology and complications of late-onset sepsis: an Italian area-based study.

Alberto Berardi, Francesca Sforza, Lorenza Baroni, Caterina Spada, Simone Ambretti, Giacomo Biasucci, Serenella Bolognesi, Mariagrazia Capretti, Edoardo Carretto, Matilde Ciccia, Marcello Lanari, Maria Federica Pedna, Vittoria Rizzo, Claudia Venturelli, Crisoula Tzialla, Laura Lucaccioni, Maria Letizia Bacchi Reggiani,

BACKGROUND:Most studies regarding late-onset sepsis (LOS) address selected populations (i.e., neonates with low birth weight or extremely preterm neonates). Studying all age groups is more suitable to assess the burden of single pathogens and their clinical relevance. METHODS:This is a retrospective regional study involving paediatric departments and NICUs in Emilia-Romagna ... Read more >>

PLoS ONE (PloS one)
[2019, 14(11):e0225407]

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Differences in cardiac phenotype and natural history of laminopathies with and without neuromuscular onset.

Raffaello Ditaranto, Giuseppe Boriani, Mauro Biffi, Massimiliano Lorenzini, Maddalena Graziosi, Matteo Ziacchi, Ferdinando Pasquale, Giovanni Vitale, Alessandra Berardini, Rita Rinaldi, Giovanna Lattanzi, Luciano Potena, Sofia Martin Suarez, Maria Letizia Bacchi Reggiani, Claudio Rapezzi, Elena Biagini,

OBJECTIVE:To investigate differences in cardiac manifestations of patients affected by laminopathy, according to the presence or absence of neuromuscular involvement at presentation. METHODS:We prospectively analyzed 40 consecutive patients with a diagnosis of laminopathy followed at a single centre between 1998 and 2017. Additionally, reports of clinical evaluations and tests prior ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2019, 14(1):263]

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In vitro thrombogenicity of drug-eluting and bare metal stents.

Tullio Palmerini, Chiara Barozzi, Luciana Tomasi, Diego Della Riva, Mario Marengo, Gianfranco Cicoria, Antonio G Bruno, Maria-Letizia Bacchi-Reggiani, Marina Naldi, Manuela Bartolini, Stefano Fanti, Nazzareno Galiè, Gregg W Stone,

AIMS:We sought to investigate the thrombogenicity of different DES and BMS in an in vitro system of stent perfusion. MATERIAL AND METHODS:The experimental model consisted of a peristaltic pump connected to 4 parallel silicone tubes in which different stents were deployed. Blood was drawn from healthy volunteers and the amount ... Read more >>

Thromb. Res. (Thrombosis research)
[2020, 185:43-48]

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Surgical Risk Scores Applied to Transcatheter Aortic Valve Implantation: Friends or Foes? Short-Term and Long-Term Outcomes From a Single-Center Registry.

Miriam Compagnone, Carolina Moretti, Chiara Marcelli, Nevio Taglieri, Gabriele Ghetti, Anna Corsini, Matteo Bruno, Antonio Giulio Bruno, Mateusz Orzalkiewicz, Cinzia Marrozzini, Maria-Letizia Bacchi Reggiani, Tullio Palmerini, Francesco Saia,

BACKGROUND:Transcatheter aortic valve implantation (TAVI) is a valid alternative to surgical aortic valve replacement for the treatment of symptomatic aortic stenosis. The EuroScore (ES) II, logistic EuroScore (log ES), and the Society of Thoracic Surgeons (STS) score are the most applied scores for surgical risk stratification. However, their predictive value ... Read more >>

J Invasive Cardiol (The Journal of invasive cardiology)
[2019, 31(10):E282-E288]

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Real-life comparison of pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis: A 24-month assessment.

Stefania Cerri, Matteo Monari, Aldo Guerrieri, Pierluigi Donatelli, Ilaria Bassi, Martina Garuti, Fabrizio Luppi, Sara Betti, Gianpiero Bandelli, Marco Carpano, Maria Letizia Bacchi Reggiani, Roberto Tonelli, Enrico Clini, Stefano Nava,

BACKGROUND:Real-life data on the use of pirfenidone and nintedanib to treat patients with idiopathic pulmonary fibrosis (IPF) are still scarce. METHODS:We compared the efficacy of either pirfenidone (n = 78) or nintedanib (n = 28) delivered over a 24-month period in patients with IPF, followed at two regional clinic centers in Italy, with a ... Read more >>

Respir Med (Respiratory medicine)
[2019, 159:105803]

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The complex interplay among atherosclerosis, inflammation, and degeneration in ascending thoracic aortic aneurysms.

Ornella Leone, Anna Corsini, Davide Pacini, Barbara Corti, Massimiliano Lorenzini, Vera Laus, Alberto Foà, Maria Letizia Bacchi Reggiani, Luca Di Marco, Claudio Rapezzi,

OBJECTIVE:To assess the histopathological findings of a large series of ascending thoracic aortic aneurysm (TAA) surgical specimens applying the updated classification on noninflammatory degenerative and inflammatory aortic diseases proposed by the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology clinicopathological correlations. METHODS:A total of 255 patients surgically ... Read more >>

J. Thorac. Cardiovasc. Surg. (The Journal of thoracic and cardiovascular surgery)
[2019, :]

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Multicenter observational study on the reliability of the HEART score.

Nicola Parenti, Giuseppe Lippi, Maria Letizia Bacchi Reggiani, Antonio Luciani, Mario Cavazza, Antonello Pietrangelo, Alberto Vegetti, Lucio Brugioni, Laura Bonfanti, Gianfranco Cervellin,

OBJECTIVE:To rapidly and safely identify the risk of developing acute coronary syndrome in patients with chest pain who present to the emergency department, the clinical use of the History, Electrocardiogram, Age, Risk Factors, and Troponin (HEART) scoring has recently been proposed. This study aimed to assess the inter-rater reliability of ... Read more >>

Clin Exp Emerg Med (Clinical and experimental emergency medicine)
[2019, 6(3):212-217]

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Open distal anastomosis in the frozen elephant trunk technique: initial experiences and preliminary results of arch zone 2 versus arch zone 3†.

Alessandro Leone, Luca Di Marco, Giuditta Coppola, Ciro Amodio, Marianna Berardi, Carlo Mariani, Daniela Votano, Maria Letizia Bacchi Reggiani, Roberto Di Bartolomeo, Davide Pacini,

OBJECTIVES:We compared the results of 2 groups of patients who underwent aortic arch replacement with the frozen elephant trunk technique. In the first group, the distal anastomosis was performed in arch zone 2; in the second control group, the distal anastomosis was performed in arch zone 3. METHODS:Between January 2007 ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2019, 56(3):564-571]

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Factors affecting the number of lymph nodes retrieved after colo-rectal cancer surgery: A prospective single-centre study.

Valeria Tonini, Arianna Birindelli, Stefania Bianchini, Maurizio Cervellera, Maria Letizia Bacchi Reggiani, James Wheeler, Salomone Di Saverio,

BACKGROUND:The number of harvested lymph nodes (LNs) in colorectal cancer surgery relates to oncologic radicality and accuracy of staging. In addition, it affects the choice of adjuvant therapy, as well as prognosis. The American Joint Committee on Cancer defines at least 12 LNs harvested as adequate in colorectal cancer resections. ... Read more >>

Surgeon (The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland)
[2020, 18(1):31-36]

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Risk factors for group B streptococcus early-onset disease: an Italian, area-based, case-control study.

Alberto Berardi, Caterina Spada, Roberta Creti, Simone Ambretti, Rossana Chiarabini, Agostino Barozzi, Rossella Pagano, Mario Sarti, Maria Federica Pedna, Sara Fornaciari, Milena Azzalli, Icilio Dodi, Maria Letizia Bacchi Reggiani, Angela Lanzoni, Eleonora Vaccina, Lorenzo Iughetti, Laura Lucaccioni,

Purpose: Intrapartum antibiotic prophylaxis (IAP) prevents group B streptococcus (GBS) early-onset disease (EOD). No European study evaluates the relative impact of risk factors (RFs) for EOD after a screening-based strategy and widespread IAP use We aimed to evaluate the risks of EOD in an Italian region where a screening-based strategy ... Read more >>

J. Matern. Fetal. Neonatal. Med. (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2020, 33(14):2480-2486]

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Predictors of time to sputum smear conversion in patients with pulmonary tuberculosis under treatment.

Francesco Bisognin, Francesco Amodio, Giulia Lombardi, Maria Letizia Bacchi Reggiani, Elisa Vanino, Luciano Attard, Marina Tadolini, Maria Carla Re, Paola Dal Monte,

Sputum acid-fast bacilli smear conversion is a fundamental index of treatment response and reduced infectivity in patients with pulmonary tuberculosis (P-TB). To date, there are no models to predict the time to sputum conversion based on patient characteristics. This study aims to ascertain the time to sputum conversion in patients ... Read more >>

New Microbiol. (The new microbiologica)
[2019, 42(3):171-175]

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Risk-Benefit Profile of Longer-Than-1-Year Dual-Antiplatelet Therapy Duration After Drug-Eluting Stent Implantation in Relation to Clinical Presentation.

Tullio Palmerini, Antonio G Bruno, Martine Gilard, Marie-Claude Morice, Marco Valgimigli, Gilles Montalescot, Jean-Philippe Collet, Diego Della Riva, Maria Letizia Bacchi-Reggiani, Philippe Gabriel Steg, Abdourahmane Diallo, Eric Vicaut, Gerard Helft, Masato Nakamura, Philippe Généreux, Torsten P Vahl, Gregg W Stone,

BACKGROUND:We sought to determine whether the risks and benefits of prolonging dual-antiplatelet therapy (DAPT) beyond 1 year after drug-eluting stent implantation depend on clinical presentation in a meta-analysis of randomized controlled trials. METHODS AND RESULTS:Randomized controlled trials comparing ≤1- versus >1-year DAPT after drug-eluting stent placement were searched through MEDLINE, ... Read more >>

Circ Cardiovasc Interv (Circulation. Cardiovascular interventions)
[2019, 12(3):e007541]

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Coronary artery disease and reasonably incomplete coronary revascularization in high-risk patients undergoing transcatheter aortic valve implantation.

Francesco Saia, Tullio Palmerini, Miriam Compagnone, Paola Battistini, Carolina Moretti, Nevio Taglieri, Chiara Marcelli, Antonio G Bruno, Gabriele Ghetti, Anna Corsini, Maria-Letizia Bacchi Reggiani, Cinzia Marrozzini, Claudio Rapezzi,

OBJECTIVES:To evaluate the long-term impact of coronary artery disease (CAD) and heart team-guided incomplete coronary revascularization in patients undergoing transcatheter aortic valve implantation (TAVI). BACKGROUND:Revascularization strategy of CAD diagnosed with routine coronary angiography before TAVI is uncertain. METHODS:Five hundred and forty consecutive TAVI patients were classified as having CAD or ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2020, 95(1):19-27]

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Group B Streptococcus early-onset disease and observation of well-appearing newborns.

Alberto Berardi, Caterina Spada, Maria Letizia Bacchi Reggiani, Roberta Creti, Lorenza Baroni, Maria Grazia Capretti, Matilde Ciccia, Valentina Fiorini, Lucia Gambini, Giancarlo Gargano, Irene Papa, Giancarlo Piccinini, Vittoria Rizzo, Fabrizio Sandri, Laura Lucaccioni, ,

BACKGROUND:International guidelines lack a substantial consensus regarding management of asymptomatic full-term and late preterm neonates at risk for early-onset disease (EOS). Large cohorts of newborns are suitable to increase the understanding of the safety and efficacy of a given strategy. METHODS:This is a prospective, area-based, cohort study involving regional birth ... Read more >>

PLoS ONE (PloS one)
[2019, 14(3):e0212784]

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Reply to correspondence concerning: "Role of liver and spleen stiffness in predicting the recurrence of hepatocellular carcinoma after resection".

Giovanni Marasco, Antonio Colecchia, Agostino Colli, Federico Ravaioli, Giovanni Casazza, Maria Letizia Bacchi Reggiani, Alessandro Cucchetti, Matteo Cescon, Davide Festi,

J. Hepatol. (Journal of hepatology)
[2019, 70(4):809-810]

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Role of liver and spleen stiffness in predicting the recurrence of hepatocellular carcinoma after resection.

Giovanni Marasco, Antonio Colecchia, Agostino Colli, Federico Ravaioli, Giovanni Casazza, Maria Letizia Bacchi Reggiani, Alessandro Cucchetti, Matteo Cescon, Davide Festi,

BACKGROUND & AIMS:Hepatocellular carcinoma (HCC) is a frequent complication of liver disease. When feasible, hepatic resection is the first-choice therapy. However, tumor recurrence complicates at least 2/3 hepatic resections at 5 years. Early recurrences are mainly tumor or treatment-related, but predictors of late recurrences are undefined. We aimed to evaluate the ... Read more >>

J. Hepatol. (Journal of hepatology)
[2019, 70(3):440-448]

Cited: 1 time

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Efficacy and safety of thrombus aspiration in ST-segment elevation myocardial infarction: an updated systematic review and meta-analysis of randomised clinical trials.

Nevio Taglieri, Maria Letizia Bacchi Reggiani, Gabriele Ghetti, Francesco Saia, Miriam Compagnone, Gianluca Lanati, Maria Teresa Di Dio, Antonio Bruno, Matteo Bruno, Diego Della Riva, Anna Corsini, Riccardo Narducci, Claudio Rapezzi,

BACKGROUND::The role of thrombus aspiration plus primary percutaneous coronary intervention in ST-segment elevation myocardial infarction remains controversial. METHODS::We performed a meta-analysis of 25 randomised controlled trials in which 21,740 ST-segment elevation myocardial infarction patients were randomly assigned to thrombus aspiration plus primary percutaneous coronary intervention or primary percutaneous coronary intervention. ... Read more >>

Eur Heart J Acute Cardiovasc Care (European heart journal. Acute cardiovascular care)
[2019, 8(1):24-38]

Cited: 1 time

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A Simple Screening Tool to Predict Outcomes in Older Adults Undergoing Emergency General Surgery.

Davide Zattoni, Isacco Montroni, Nicole Marie Saur, Anna Garutti, Maria Letizia Bacchi Reggiani, Caterina Galetti, Pietro Calogero, Valeria Tonini,

OBJECTIVES:To determine whether the Flemish version of the Triage Risk Screening Tool (fTRST) can be used to accurately assess frailty in an emergency setting. DESIGN:Prospective observational study. SETTING:of a tertiary referral hospital. PATIENTS:All individuals aged 70 and older consecutively admitted to the emergency surgery unit with an urgent need for ... Read more >>

J Am Geriatr Soc (Journal of the American Geriatrics Society)
[2019, 67(2):309-316]

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Prodromal angina and risk of 2-year cardiac mortality in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous intervention.

Gabriele Ghetti, Maria Letizia Bacchi Reggiani, Claudia Rosetti, Paola Battistini, Gianluca Lanati, Maria Teresa Di Dio, Anna Corsini, Matteo Bruno, Diego Della Riva, Antonio Giulio Bruno, Miriam Compagnone, Riccardo Narducci, Francesco Saia, Claudio Rapezzi, Nevio Taglieri,

We sought to investigate the prognostic significance of prodromal angina (PA) in unselected patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) and its additive predictive value to the GRACE score.We prospectively enrolled 3015 consecutive STEMI patients undergoing PPCI. Patients were divided in 2 groups according ... Read more >>

Medicine (Baltimore) (Medicine)
[2018, 97(37):e12332]

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