Full Text Journal Articles by
Author Margherita Padeletti

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Complex Arrhythmias Due to Reversible Causes.

Andrea Pozzolini, Teresa Rio, Margherita Padeletti, Roberto De Ponti, Fabio M Leonelli, Giuseppe Bagliani,

Abnormalities in cardiac rhythm are caused by disorders of impulse generation, conduction, or a combination of the 2, and may be life-threatening because of a reduction in cardiac output or myocardial oxygenation. Cardiac arrhythmias are commonly classified as tachycardias (supraventricular or ventricular) or bradycardias. Bradycardias are uncommon in the critically ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2019, 11(2):375-390]

Cited: 0 times

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Surface Electrocardiogram Recording: Baseline 12-lead and Ambulatory Electrocardiogram Monitoring.

Margherita Padeletti, Giuseppe Bagliani, Roberto De Ponti, Fabio M Leonelli, Emanuela T Locati,

The 12-lead standard electrocardiogram (ECG) is a 10 second recording of human myocytes electrical activity. Filters and oversampling are necessary in order to acquire a smooth signal without distortion. ECG recordings may display ongoing arrhythmias, and some leads may be helpful in formulating the diagnosis. Advanced modalities of baseline ECG recording ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2019, 11(2):189-201]

Cited: 0 times

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Electrocardiogram and Imaging: An Integrated Approach to Arrhythmogenic Cardiomyopathies.

Ketty Savino, Giuseppe Bagliani, Federico Crusco, Margherita Padeletti, Massimo Lombardi,

Cardiovascular imaging has radically changed the management of patients with arrhythmogenic cardiomyopathies. This article focuses on the role of echocardiography and MRI in the diagnosis of these structural diseases. Cardiomyopathies with hypertrophic pattern (hypertrophic cardiomyopathy, restrictive cardiomyopathies, amyloidosis, Anderson-Fabry disease, and sarcoidosis), cardiomyopathies with dilated pattern, inflammatory cardiac diseases, and ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2018, 10(2):413-429]

Cited: 0 times

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Ectopic Beats: Insights from Timing and Morphology.

Giuseppe Bagliani, Domenico Giovanni Della Rocca, Roberto De Ponti, Alessandro Capucci, Margherita Padeletti, Andrea Natale,

Premature complexes are electrical impulses arising from atrial, junctional, or ventricular tissue, leading to premature heart beats. Premature atrial beats are much more frequent than those arising in the atrioventricular junction but less frequent than premature beats from the ventricles. Although they are usually benign and highly prevalent in the ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2018, 10(2):257-275]

Cited: 0 times

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Complexity in internal medicine wards: A novel screening method and implications for management.

Fabrizio Bandini, Stefano Guidi, Silvia Blaszczyk, Antonietta Fumarulo, Michela Pierini, Paolo Pratesi, Stefano Spolveri, Margherita Padeletti, Pasquale Petrone, Paolo Zoppi, Giancarlo Landini,

RATIONALE:Complexity is increasingly recognized as a critical variable in health care. However, there is still lack of practical tools to assess it and tackle the challenges that stem from it, particularly within hospitals. AIMS AND OBJECTIVE:To validate a simple novel screening method based on both objective and subjective criteria to ... Read more >>

J Eval Clin Pract (Journal of evaluation in clinical practice)
[2018, 24(1):285-292]

Cited: 1 time

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Meta-analysis of Clinical Outcomes of Electrical Cardioversion and Catheter Ablation in Patients with Atrial Fibrillation and Chronic Kidney Disease.

Igor Diemberger, Simonetta Genovesi, Giulia Massaro, Maria Letizia Bacchi Reggiani, Jessica Frisoni, Giulia Gorlato, Erminio Mauro, Margherita Padeletti, Antonio Vincenti, Giuseppe Boriani,

BACKGROUND:Chronic kidney disease (CKD) is associated with adverse outcomes in presence of atrial fibrillation (AF). However, the literature shows limited data on non-pharmacological management of AF in CKD patients. AIM:summarizing the available data on outcomes associated with electrical cardioversion (ECV) and AF catheter ablation (CA) in CKD patients. METHODS:We searched ... Read more >>

Curr. Pharm. Des. (Current pharmaceutical design)
[2018, 24(24):2794-2801]

Cited: 0 times

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Cardiac resynchronization therapy improves functional status and cognition.

Stefano Fumagalli, Paolo Pieragnoli, Giuseppe Ricciardi, Giuseppe Mascia, Franco Mascia, Federica Michelotti, Giosuè Mascioli, Matteo Beltrami, Margherita Padeletti, Martina Nesti, Niccolò Marchionni, Luigi Padeletti,

Many trials demonstrated the beneficial effects on hospitalizations and mortality of cardiac resynchronization therapy (CRT). The purpose of this study was to evaluate CRT effects on functional performance and cognition, two determinants of disability, frailty development and survival.All consecutive patients receiving a CRT device were evaluated at baseline and at ... Read more >>

Int. J. Cardiol. (International journal of cardiology)
[2016, 219:212-217]

Cited: 3 times

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Simultaneous His Bundle and Left Ventricular Pacing for Optimal Cardiac Resynchronization Therapy Delivery: Acute Hemodynamic Assessment by Pressure-Volume Loops.

Luigi Padeletti, Paolo Pieragnoli, Giuseppe Ricciardi, Lisa Innocenti, Luca Checchi, Margherita Padeletti, Antonio Michelucci, Francesco Picariello, Sergio Valsecchi,

Previous studies have investigated the role of intrinsic conduction in optimizing cardiac resynchronization therapy. We investigated the role of fusing pacing-induced activation and intrinsic conduction in cardiac resynchronization therapy by evaluating the acute hemodynamic effects of simultaneous His-bundle (HIS) and left ventricular (LV) pacing.We studied 11 patients with systolic heart ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2016, 9(5):]

Cited: 1 time

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Chronic kidney disease and worsening renal function in acute heart failure: different phenotypes with similar prognostic impact?

Alberto Palazzuoli, Carlo Lombardi, Gaetano Ruocco, Margherita Padeletti, Ranuccio Nuti, Marco Metra, Claudio Ronco,

Nearly a third of patients with acute heart failure experience concomitant renal dysfunction. This condition is often associated with increased costs of care, length of hospitalisation and high mortality. Although the clinical impact of chronic kidney disease (CKD) has been well established, the exact clinical significance of worsening renal function ... Read more >>

Eur Heart J Acute Cardiovasc Care (European heart journal. Acute cardiovascular care)
[2016, 5(8):534-548]

Cited: 6 times

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Novel echocardiographic techniques for the evaluation of athletes' heart: A focus on speckle-tracking echocardiography.

Flavio D'Ascenzi, Stefano Caselli, Marco Solari, Antonio Pelliccia, Matteo Cameli, Marta Focardi, Margherita Padeletti, Domenico Corrado, Marco Bonifazi, Sergio Mondillo,

The development and rapid dissemination of two-dimensional echocardiography led to important further advances in our understanding of athletes' heart that has been the subject of several echocardiographic studies involving many thousands of athletes. The description of ventricular chamber enlargement, myocardial hypertrophy and atrial dilatation has led to a more comprehensive ... Read more >>

Eur J Prev Cardiol (European journal of preventive cardiology)
[2016, 23(4):437-446]

Cited: 24 times

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Training-induced dynamic changes in left atrial reservoir, conduit, and active volumes in professional soccer players.

Flavio D'Ascenzi, Antonio Pelliccia, Benedetta Maria Natali, Matteo Cameli, Matteo Lisi, Marta Focardi, Margherita Padeletti, Paola Palmitesta, Domenico Corrado, Marco Bonifazi, Sergio Mondillo, Michael Henein,

Although left atrial (LA) enlargement is a recognized component of athlete's heart, dynamic cavity changes occurring during the training period remain to be elucidated. We aimed to investigate the adaptive changes of LA reservoir, conduit, and active volumes in elite athletes vs. controls and their response to different training loads.LA ... Read more >>

Eur. J. Appl. Physiol. (European journal of applied physiology)
[2015, 115(8):1715-1723]

Cited: 4 times

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Increased left atrial size is associated with reduced atrial stiffness and preserved reservoir function in athlete's heart.

Flavio D'Ascenzi, Antonio Pelliccia, Benedetta Maria Natali, Matteo Cameli, Valentina Andrei, Eufemia Incampo, Federico Alvino, Matteo Lisi, Margherita Padeletti, Marta Focardi, Marco Bonifazi, Sergio Mondillo,

Left atrial (LA) fibrosis with increased stiffness has been assumed to be the substrates for occurrence of atrial arrhythmias in athletes. However, this hypothesis has not yet been confirmed in humans. Aim of this study was, therefore, to assess LA remodeling and stiffness in competitive athletes. 150 competitive athletes and ... Read more >>

Int J Cardiovasc Imaging (The international journal of cardiovascular imaging)
[2015, 31(4):699-705]

Cited: 5 times

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Cardiac resynchronization therapy acutely improves ventricular-arterial coupling by reducing the arterial load: assessment by pressure-volume loops.

Paolo Pieragnoli, Giovanni Battista Perego, Giuseppe Ricciardi, Stefania Sacchi, Margherita Padeletti, Antonio Michelucci, Sergio Valsecchi, Luigi Padeletti,

Cardiac resynchronization therapy (CRT) has been demonstrated to improve ventricular-arterial coupling by reducing effective arterial elastance (Ea) on long-term follow-up. Detailed invasive studies showing possible acute peripheral effects of CRT are not available. We evaluated the hemodynamic effects of CRT in patients with systolic dysfunction, in order to investigate the ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2015, 38(4):431-437]

Cited: 3 times

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Endurance and Strength Athlete's Heart: Analysis of Myocardial Deformation by Speckle Tracking Echocardiography.

Amato Santoro, Federico Alvino, Giovanni Antonelli, Maria Caputo, Margherita Padeletti, Matteo Lisi, Sergio Mondillo,

BACKGROUND: Intensive training induces two morphological myocardial typologies of athlete's heart. Endurance training (ET) induces eccentric remodeling, bradycardia and better diastolic filling. Strength training (ST) determines concentric chamber remodelling maintaining a normal heart rate (HR). Aim of the study was to compare ET and ST athletes' heart using speckle tracking ... Read more >>

J Cardiovasc Ultrasound (Journal of cardiovascular ultrasound)
[2014, 22(4):196-204]

Cited: 10 times

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Simplified Selvester Score: a practical electrocardiographic instrument to predict response to CRT.

Rossella Bani, Luca Checchi, Stella Cartei, Paolo Pieragnoli, Giuseppe Ricciardi, Alessandro Paoletti Perini, Margherita Padeletti, Federica Michelotti, Antonio Michelucci, Giosuè Mascioli, Luigi Padeletti,

To investigate the LBBB Selvester Scoring System (LBBB-SSc) and the Simplified-SSc prognostic impact in predicting response to CRT, all cause and cardiac mortality, heart failure (HF) hospitalizations and onset of arrhythmias in HF patients undergoing CRT.We retrospectively evaluated LBBB-SSc and Simplified-SSc of 172 consecutive HF patients with true-LBBB who underwent ... Read more >>

J Electrocardiol (Journal of electrocardiology)
[2015, 48(1):62-68]

Cited: 2 times

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Determinants of all-cause mortality in different age groups in patients with severe systolic left ventricular dysfunction receiving an implantable cardioverter defibrillator (from the Italian ClinicalService Multicenter Observational Project).

Stefano Fumagalli, Maurizio Gasparini, Maurizio Landolina, Maurizio Lunati, Giuseppe Boriani, Alessandro Proclemer, Massimo Santini, Lorenza Mangoni, Margherita Padeletti, Niccolò Marchionni, Luigi Padeletti, ,

Heart failure (HF) is a common condition in elderly patients. Despite great improvements in medical therapy, HF mortality remains high. Implantable cardioverter defibrillator (ICD) significantly lengthens the survival rate of subjects with severe HF, but little evidence exists on its effect in elderly persons. Aim of this study was to ... Read more >>

Am. J. Cardiol. (The American journal of cardiology)
[2014, 113(10):1691-1696]

Cited: 6 times

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Sleep-disordered breathing increases the risk of arrhythmias.

Margherita Padeletti, Valerio Zacà, Sergio Mondillo, Sanja Jelic,

Sleep-disordered breathing (SDB) has been consistently associated with increased risk for cardiovascular diseases, including arrhythmias. The purpose of this review is to elucidate the several pathophysiologic pathways such as repetitive hypoxia and reoxygenation, increased oxidative stress, inflammation and sympathetic activation that may underlie the increased incidence of arrhythmias in SDB ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2014, 15(5):411-416]

Cited: 3 times

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Metabolomic does not predict response to cardiac resynchronization therapy in patients with heart failure.

Luigi Padeletti, Pietro A Modesti, Stella Cartei, Luca Checchi, Giuseppe Ricciardi, Paolo Pieragnolia, Stefania Sacchi, Margherita Padeletti, Brunetto Alterini, Pietro Pantaleo, Xiaoyu Hu, Leonardo Tenori, Claudio Luchinat,

AIMS: Metabolomic, a systematic study of metabolites, may be a useful tool in understanding the pathological processes that underlie the occurrence and progression of a disease. We hypothesized that metabolomic would be helpful in assessing a specific pattern in heart failure patients, also according to the underlining causes and in ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2014, 15(4):295-300]

Cited: 4 times

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Effect of bosentan on pulmonary hypertension secondary to systolic heart failure.

Margherita Padeletti, Maria Caputo, Valerio Zacà, Charilos Tsioulpas, Sonia Bernazzali, Sergio Mondillo, Massimo Maccherini, Sanja Jelic,

The dual endothelin receptor antagonist bosentan improves pulmonary vascular resistance (PVR) in patients with primary pulmonary hypertension (PH). The effects of bosentan on secondary PH due to systolic heart failure (HF) are not well defined. This study evaluates the effect and tolerability of bosentan in patients with PH secondary to ... Read more >>

Pharmacology (Pharmacology)
[2013, 92(5-6):281-285]

Cited: 4 times

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Comparison of right versus left ventricular strain analysis as a predictor of outcome in patients with systolic heart failure referred for heart transplantation.

Matteo Cameli, Francesca Maria Righini, Matteo Lisi, Elena Bennati, Romina Navarri, Stefano Lunghetti, Margherita Padeletti, Paolo Cameli, Charilaos Tsioulpas, Sonia Bernazzali, Massimo Maccherini, Guido Sani, Michael Henein, Sergio Mondillo,

The aim of the present study was to explore the relation between right ventricular (RV) and left ventricular (LV) echocardiographic parameters with clinical outcome in patients with advanced heart failure referred for cardiac transplantation. Ninety-eight consecutive patients with advanced systolic heart failure, referred for cardiac transplant evaluation, were enrolled. All ... Read more >>

Am. J. Cardiol. (The American journal of cardiology)
[2013, 112(11):1778-1784]

Cited: 27 times

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Platypnoea-orthodeoxia syndrome after an acute ischemic stroke.

Pierpaolo Cannarile, Margherita Padeletti, Massimo Fineschi, Sergio Mondillo, Carlo Pierli,

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2013, 14(8):603-604]

Cited: 0 times

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Detection of early left ventricular and atrial dysfunction in overweight patients with preserved ejection fraction: a speckle tracking analysis.

Maria Caputo, Rossella Urselli, Valerio Zacà, Eugenia Capati, Margherita Padeletti, Silvia De Nicola, Romina Navarri, Giovanni Antonelli, Claudia Nucci, Elisa Giacomin, Sergio Mondillo,

BACKGROUND: Little remains known about the role of overweight to promote progressive atrial and ventricular myocardial dysfunction. Aim of this study was to investigate the potential influence of overweight on left ventricular (LV) and atrial (LA) function, as assessed by speckle tracking strain analysis, in patients at low-to-moderate global cardiovascular ... Read more >>

Echocardiography (Echocardiography (Mount Kisco, N.Y.))
[2013, 30(5):551-557]

Cited: 6 times

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Larger interventricular conduction time enhances mechanical response to resynchronization therapy.

Luigi Padeletti, Paolo Pieragnoli, Giuseppe Ricciardi, Laura Perrotta, Alessandro P Perini, Gino Grifoni, Ilaria Ricceri, Margherita Padeletti, Vincenzo Lionetti, Sergio Valsecchi,

BACKGROUND: Previous studies have reported that the left ventricular (LV) pacing site is a major determinant of the hemodynamic response to cardiac resynchronization therapy (CRT). However, lead positioning in a lateral or posterolateral cardiac vein may not be optimal for every patient. The objective of this study was to assess ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2013, 36(4):416-423]

Cited: 3 times

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Characterization of right atrial function and dimension in top-level athletes: a speckle tracking study.

Flavio D'Ascenzi, Matteo Cameli, Margherita Padeletti, Matteo Lisi, Valerio Zacà, Benedetta Natali, Angela Malandrino, Federico Alvino, Massimo Morelli, Gian Maria Vassallo, Cosetta Meniconi, Marco Bonifazi, Andrea Causarano, Sergio Mondillo,

Although many echocardiographic studies are available about the adaptation of left ventricle to intensive training, right heart function has been poorly investigated and no data are available about the right atrial (RA) function in top-level athletes. The aim of the study was to investigate RA function and dimension by standard ... Read more >>

Int J Cardiovasc Imaging (The international journal of cardiovascular imaging)
[2013, 29(1):87-94]

Cited: 25 times

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Reference values of right atrial longitudinal strain imaging by two-dimensional speckle tracking.

Margherita Padeletti, Matteo Cameli, Matteo Lisi, Angela Malandrino, Valerio Zacà, Sergio Mondillo,

BACKGROUND: The role of speckle tracking in the assessment of right atrial (RA) deformation dynamics has not been established yet. The reference ranges of RA longitudinal strain indices were measured by speckle tracking in a population of normal subjects. METHODS: In 84 healthy individuals, peak atrial longitudinal strain (PALS), peak ... Read more >>

Echocardiography (Echocardiography (Mount Kisco, N.Y.))
[2012, 29(2):147-152]

Cited: 32 times

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