Full Text Journal Articles by
Author Margaret Breen Lyles

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Editorial: understanding IBS pathophysiology through "converging channels" of research-authors' reply.

Madhusudan Grover, Antonio Berumen, Stephanie Peters, Ting Wei, Margaret Breen-Lyles, William S Harmsen, Irene Busciglio, Duane Burton, Maria Vazquez Roque, Kenneth R DeVault, Michael Camilleri, Michael Wallace, Surendra Dasari, Helmut Neumann, Lesley A Houghton,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(9):1215-1216]

Cited: 0 times

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Intestinal chemosensitivity in irritable bowel syndrome associates with small intestinal TRPV channel expression.

Madhusudan Grover, Antonio Berumen, Stephanie Peters, Ting Wei, Margaret Breen-Lyles, William S Harmsen, Irene Busciglio, Duane Burton, Maria Vazquez Roque, Kenneth R DeVault, Michael Camilleri, Michael Wallace, Surendra Dasari, Helmut Neumann, Lesley A Houghton,

<h4>Background</h4>Irritable bowel syndrome (IBS) patients often experience meal-associated symptoms. However, the underlying mechanisms are unclear.<h4>Aim</h4>To determine small intestinal mechanisms of lipid-induced symptoms and rectal hypersensitivity in IBS METHODS: We recruited 26 IBS patients (12 IBS-C, 14 IBS-D) and 15 healthy volunteers (HV). In vivo permeability was assessed using saccharide excretion ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(9):1179-1192]

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Response to Oliviero et al.'s publication: "Impact of COVID-19 lockdown on symptoms in patients with functional gastrointestinal disorders: Relationship with anxiety and perceived stress".

Xiao Jing Wang, Brenna Murphy, Margaret Breen-Lyles, Jean Fox,

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2021, :e14207]

Cited: 0 times

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Development and Validation of Test for "Leaky Gut" Small Intestinal and Colonic Permeability Using Sugars in Healthy Adults.

Katayoun Khoshbin, Lehar Khanna, Daniel Maselli, Jessica Atieh, Margaret Breen-Lyles, Kayla Arndt, Deborah Rhoten, Roy B Dyer, Ravinder J Singh, Sunita Nayar, Sandra Bjerkness, William S Harmsen, Irene Busciglio, Michael Camilleri,

<h4>Background</h4>Oral monosaccharides and disaccharides are used to measure in vivo human gut permeability through urinary excretion.<h4>Aims</h4>The aims were as follows: (1) to obtain normative data on small intestinal and colonic permeability; (2) to assess variance on standard 16 g fiber diet performed twice; (3) to determine whether dietary fiber influences gut ... Read more >>

Gastroenterology (Gastroenterology)
[2021, 161(2):463-475.e13]

Cited: 1 time

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Psychological, physical, and sleep comorbidities and functional impairment in irritable bowel syndrome: Results from a national survey of U.S. adults.

Madhusudan Grover, Bhanu Prakash Kolla, Rahul Pamarthy, Meghna P Mansukhani, Margaret Breen-Lyles, Jian-Ping He, Kathleen R Merikangas,

<h4>Background/aims</h4>Patients with irritable bowel syndrome (IBS) in referral practice commonly report mental disorders and functional impairment. Our aim was to determine the prevalence of mental, physical and sleep-related comorbidities in a nationally representative sample of IBS patients and their impact on functional impairment.<h4>Methods</h4>IBS was defined by modified Rome Criteria based ... Read more >>

PLoS One (PloS one)
[2021, 16(1):e0245323]

Cited: 1 time

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Gastric accommodation influences proximal gastric and total gastric emptying in concurrent measurements conducted in healthy volunteers.

Xiao Jing Wang, Duane D Burton, Margaret Breen-Lyles, Michael Camilleri,

Gastric emptying and gastric accommodation play a role in generation of upper gastrointestinal symptoms. Although both functions have been measured simultaneously using MRI or <sup>99m</sup>Tc SPECT methodology, the correlation of these two functions has not been evaluated simultaneously using a solid and liquid meal. To study relationships of whole or ... Read more >>

Am J Physiol Gastrointest Liver Physiol (American journal of physiology. Gastrointestinal and liver physiology)
[2021, 320(5):G759-G767]

Cited: 2 times

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Comparing Clinical, Imaging, and Physiological Correlates of Intestinal Pseudo-Obstruction: Systemic Sclerosis vs Amyloidosis and Paraneoplastic Syndrome.

Rahul Pamarthy, Antonio Berumen, Margaret Breen-Lyles, Madhusudan Grover, Ashima Makol,

<h4>Introduction</h4>Intestinal pseudo-obstruction is characterized by impaired transit and luminal dilation in the absence of mechanical obstruction. Our study aims to describe the clinical, radiographic, and physiological findings in pseudo-obstruction associated with systemic sclerosis (SSc), amyloidosis, and paraneoplastic syndrome.<h4>Methods</h4>A retrospective cohort of patients evaluated at our institution between January 1, 2008, ... Read more >>

Clin Transl Gastroenterol (Clinical and translational gastroenterology)
[2020, 11(8):e00206]

Cited: 0 times

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Characteristics and Risk Factors of Post-Infection Irritable Bowel Syndrome After Campylobacter Enteritis.

Antonio Berumen, Ryan Lennon, Margaret Breen-Lyles, Jayne Griffith, Robin Patel, David Boxrud, Marijke Decuir, Gianrico Farrugia, Kirk Smith, Madhusudan Grover,

<h4>Background & aims</h4>Campylobacter is the leading cause of bacterial gastroenteritis in the United States. We investigated the prevalence of postinfection irritable bowel syndrome (PI-IBS) in a cohort with culture-confirmed Campylobacter cases; risk factors for PI-IBS based on clinical factors; and shifts in IBS patterns postinfection in patients with pre-existing IBS.<h4>Methods</h4>The ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, 19(9):1855-1863.e1]

Cited: 2 times

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Association of social network factors with weight status and weight loss intentions among hispanic adults.

Mark L Wieland, Jane W Njeru, Janet M Okamoto, Paul J Novotny, Margaret K Breen-Lyles, Miriam Goodson, Graciela D Porraz Capetillo, Luz E Molina, Irene G Sia,

Hispanic adults have the highest obesity prevalence in the United States, but little is known about weight-related social network influences. A community-based sample of 610 Hispanic participants completed height/weight and a survey. The proportion of overweight or obese (OW/OB) network members was higher for OW/OB respondents compared to normal weight ... Read more >>

J Behav Med (Journal of behavioral medicine)
[2020, 43(2):155-165]

Cited: 1 time

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Social networks and obesity among Somali immigrants and refugees.

Jane W Njeru, Mark L Wieland, Janet M Okamoto, Paul J Novotny, Margaret K Breen-Lyles, Ahmed Osman, Yahye A Ahmed, Mohamud A Nur, Omar Nur, Irene G Sia,

BACKGROUND:Somali immigrants and refugees to the United States are at high risk for obesity and related cardiovascular risk. Social network factors influence health behaviors and are important contributors to the obesity epidemic. The objective of this study was to describe social networks and obesity-related characteristics among adult Somali immigrants in ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):238]

Cited: 1 time

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Comparison of the QuantiFERON-TB Gold Plus and QuantiFERON-TB Gold In-Tube Interferon Gamma Release Assays in Patients at Risk for Tuberculosis and in Health Care Workers.

Elitza S Theel, Heather Hilgart, Margaret Breen-Lyles, Kevin McCoy, Rhiannon Flury, Laura E Breeher, John Wilson, Irene G Sia, Jennifer A Whitaker, Jeremy Clain, Timothy R Aksamit, Patricio Escalante,

The QuantiFERON-TB Gold Plus (QFT-Plus; Qiagen, Germantown, MD) interferon gamma release assay (IGRA) received FDA clearance in 2017 and will replace the prior version of the assay, the QFT-Gold In-Tube (QFT-GIT). Here, we compared performances of the QFT-Plus assay and the QFT-GIT version in a diverse patient population, including patients ... Read more >>

J Clin Microbiol (Journal of clinical microbiology)
[2018, 56(7):]

Cited: 20 times

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