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Author Marek Ujda

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Catheter ablation of complex arrhythmic anomalies: Bayes syndrome, Wolff-Parkinson-White syndrome, atrial and dilated cardiomyopathy.

Piotr J Stec, Michał Chrabąszcz, Marek Ujda, Radosław Krawczykiewicz, Janusz Śledź, Sebastian Stec,

HeartRhythm Case Rep (HeartRhythm case reports)
[2019, 5(9):476-479]

Cited: 0 times

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Maximum voltage gradient technique for optimization of ablation for typical atrial flutter with zero-fluoroscopy approach.

Karol Deutsch, Janusz Śledź, Mariusz Mazij, Bartosz Ludwik, Michał Labus, Dariusz Karbarz, Bernadetta Pasicka, Michał Chrabąszcz, Arkadiusz Śledź, Monika Klank-Szafran, Laura Vitali-Sendoz, Tomasz Kameczura, Jerzy Śpikowski, Piotr Stec, Marek Ujda, Sebastian Stec,

Radiofrequency catheter ablation (RFCA) is an established effective method for the treatment of typical cavo-tricuspid isthmus (CTI)-dependent atrial flutter (AFL). The introduction of 3-dimensional electro-anatomic systems enables RFCA without fluoroscopy (No-X-Ray [NXR]). The aim of this study was to evaluate the feasibility and effectiveness of CTI RFCA during implementation of ... Read more >>

Medicine (Baltimore) (Medicine)
[2017, 96(25):e6939]

Cited: 1 time

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Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial.

Stephen J Nicholls, John J P Kastelein, Gregory G Schwartz, Dianna Bash, Robert S Rosenson, Matthew A Cavender, Danielle M Brennan, Wolfgang Koenig, J Wouter Jukema, Vijay Nambi, R Scott Wright, Venu Menon, A Michael Lincoff, Steven E Nissen, ,

Secretory phospholipase A2 (sPLA2) generates bioactive phospholipid products implicated in atherosclerosis. The sPLA2 inhibitor varespladib has favorable effects on lipid and inflammatory markers; however, its effect on cardiovascular outcomes is unknown.To determine the effects of sPLA2 inhibition with varespladib on cardiovascular outcomes.A double-blind, randomized, multicenter trial at 362 academic and ... Read more >>

JAMA (JAMA)
[2014, 311(3):252-262]

Cited: 98 times

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Pretreatment with prasugrel in non-ST-segment elevation acute coronary syndromes.

Gilles Montalescot, Leonardo Bolognese, Dariusz Dudek, Patrick Goldstein, Christian Hamm, Jean-Francois Tanguay, Jurrien M ten Berg, Debra L Miller, Timothy M Costigan, Jochen Goedicke, Johanne Silvain, Paolo Angioli, Jacek Legutko, Margit Niethammer, Zuzana Motovska, Joseph A Jakubowski, Guillaume Cayla, Luigi Oltrona Visconti, Eric Vicaut, Petr Widimsky, ,

BACKGROUND: Although P2Y12 antagonists are effective in patients with non-ST-segment elevation (NSTE) acute coronary syndromes, the effect of the timing of administration--before or after coronary angiography--is not known. We evaluated the effect of administering the P2Y12 antagonist prasugrel at the time of diagnosis versus administering it after the coronary angiography ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2013, 369(11):999-1010]

Cited: 183 times

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Effects of dalcetrapib in patients with a recent acute coronary syndrome.

Gregory G Schwartz, Anders G Olsson, Markus Abt, Christie M Ballantyne, Philip J Barter, Jochen Brumm, Bernard R Chaitman, Ingar M Holme, David Kallend, Lawrence A Leiter, Eran Leitersdorf, John J V McMurray, Hardi Mundl, Stephen J Nicholls, Prediman K Shah, Jean-Claude Tardif, R Scott Wright, ,

BACKGROUND: In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a lower risk of coronary heart disease events. However, whether raising HDL cholesterol levels therapeutically reduces cardiovascular risk remains uncertain. Inhibition of cholesteryl ester transfer protein (CETP) raises HDL cholesterol levels and might therefore improve ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2012, 367(22):2089-2099]

Cited: 803 times

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Clopidogrel with or without omeprazole in coronary artery disease.

Deepak L Bhatt, Byron L Cryer, Charles F Contant, Marc Cohen, Angel Lanas, Thomas J Schnitzer, Thomas L Shook, Pablo Lapuerta, Mark A Goldsmith, Loren Laine, Benjamin M Scirica, Sabina A Murphy, Christopher P Cannon, ,

Gastrointestinal complications are an important problem of antithrombotic therapy. Proton-pump inhibitors (PPIs) are believed to decrease the risk of such complications, though no randomized trial has proved this in patients receiving dual antiplatelet therapy. Recently, concerns have been raised about the potential for PPIs to blunt the efficacy of clopidogrel.We ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2010, 363(20):1909-1917]

Cited: 488 times

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Antianginal efficacy of omapatrilat in patients with chronic angina pectoris.

Bernard R Chaitman, Alla Y Ivleva, Marek Ujda, Jacque H F Lenis, Csaba Toth, David M Stieber, Leonardo H Reisin, Andreas M Pangerl, Julie B Friedman, John H Lawrence,

Angiotensin-converting enzyme inhibition is not an effective antianginal therapy. Experimental data suggest that broader vasopeptidase inhibition may decrease the magnitude of demand-induced myocardial ischemia. A randomized, double-blind, placebo controlled parallel study evaluated omapatrilat, an inhibitor of angiotensin-converting enzyme and neutral endopeptidase. The primary objective was to compare maximum duration of ... Read more >>

Am. J. Cardiol. (The American journal of cardiology)
[2005, 95(11):1283-1289]

Cited: 7 times

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Mechanism of the contractile effects of galantide and Galanin(1-14) [alpha-aminobutyric acid]scyliorhinin-I in rat isolated fundus strips.

Roman P Korolkiewicz, Zdziaław Konstanski, Piotr Rekowski, Agnieszka Szyk, Jaroslaw Ruczyński, Jaroslaw Dabrowski, Marek Ujda, Konstanty Zbigniew Korolkiewicz, Jacek Petrusewicz,

BACKGROUND: The study was undertaken to establish the pharmacological basis of the stimulatory activity of galantide (M15) and galanin(1-14)-(a-aminobutyric acid8-[Abu8])scyliorhinin-I [Scy-I] in gastric smooth muscle. MATERIAL/METHODS: Isotonic contractions of the isolated, longitudinal rat gastric fundus strips were recorded. RESULTS: Galanin, galanin(1-15)-NH2, M15 and galanin(1-14)-[Abu8]Scy-I elicited concentration-dependent contractions. Their EC50s equaled ... Read more >>

Med. Sci. Monit. (Medical science monitor : international medical journal of experimental and clinical research)
[2002, 8(1):BR19-23]

Cited: 1 time

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Differential salutary effects of nonselective and selective COX-2 inhibitors in postoperative ileus in rats.

Roman P Korolkiewicz, Marek Ujda, Jarosław Dabkowski, Jarosław Ruczyński, Piotr Rekowski, Jacek Petrusewicz,

BACKGROUND:Postoperative ileus (PI) is a common surgical complication, the treatment of which consists of supportive measures. AIM:The effects of several cyclooxygenase (COX) inhibitors and their interaction with L-arginine/nitric oxide synthase (NOS) pathway were tested in a rat PI model. METHODS:Intestinal transit was measured as Evans blue migration after skin incision, ... Read more >>

J. Surg. Res. (The Journal of surgical research)
[2003, 109(2):161-169]

Cited: 28 times

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