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Author Marco Valerio Mariani

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Impact of COVID-19 Pandemic on Cardiac Electronic Device Management and Role of Remote Monitoring

Michele Magnocavallo, Giampaolo Vetta, Alessia Bernardini, Agostino Piro, Maria Chiara Mei, Martina Di Iorio, Marco Valerio Mariani, Domenico G. Della Rocca, Paolo Severino, Raffaele Quaglione, Giuseppe Giunta, Cristina Chimenti, Fabio Miraldi, Carmine Dario Vizza, Francesco Fedele, Carlo Lavalle,

Synopsis During the Coronavirus Disease 2019 (COVID-19) worldwide pandemic, patients with cardiac implantable electronic device (CIED) refused scheduled follow-up visits due to the risk of infection. In this scenario, different telemedicine strategies have been implemented to ensure continuity of care to CIED patients. Patients can be monitored through dedicated apps, ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

Cited: 0 times

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New evidence of direct oral anticoagulation therapy on cardiac valve calcifications, renal preservation and inflammatory modulation.

Luca Di Lullo, Carlo Lavalle, Michele Magnocavallo, Marco Valerio Mariani, Domenico Giovanni Della Rocca, Paolo Severino, Biagio Raffaele Di Iorio, Domenico Russo, Francesco Summaria, Giovanni Battista Forleo, Claudio Ronco, Massimo Mancone, Cristina Chimenti, Fabio Miraldi, Andrea Natale, Antonio Bellasi,

<h4>Background</h4>Rivaroxaban is a direct inhibitor of activated Factor X (FXa), an anti-inflammatory protein exerting a protective effect on the cardiac valve and vascular endothelium. We compare the effect of Warfarin and Rivaroxaban on inflammation biomarkers and their contribution to heart valve calcification progression and renal preservation in a population of ... Read more >>

Int J Cardiol (International journal of cardiology)
[2021, 345:90-97]

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Diagnosis and Treatment of Idiopathic Premature Ventricular Contractions: A Stepwise Approach Based on the Site of Origin.

Daniele Muser, Massimo Tritto, Marco Valerio Mariani, Antonio Di Monaco, Paolo Compagnucci, Michele Accogli, Roberto De Ponti, Fabrizio Guarracini,

Premature ventricular contractions in the absence of structural heart disease are among the most common arrhythmias in clinical practice, with well-defined sites of origin in the right and left ventricle. In this review, starting from the electrocardiographic localization of premature ventricular contractions, we investigated the mechanisms, prevalence in the general ... Read more >>

Diagnostics (Basel) (Diagnostics (Basel, Switzerland))
[2021, 11(10):]

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Potential Role of eNOS Genetic Variants in Ischemic Heart Disease Susceptibility and Clinical Presentation.

Paolo Severino, Andrea D'Amato, Silvia Prosperi, Michele Magnocavallo, Marco Valerio Mariani, Lucrezia Netti, Lucia Ilaria Birtolo, Paolo De Orchi, Cristina Chimenti, Viviana Maestrini, Fabio Miraldi, Carlo Lavalle, Viviana Caputo, Raffaele Palmirotta, Massimo Mancone, Francesco Fedele,

<b>Background:</b> IHD is determined by an inadequate coronary blood supply to the myocardium, and endothelial dysfunction may represent one of the main pathophysiological mechanisms involved. Genetic predisposition to endothelial dysfunction has been associated with IHD and its clinical manifestation. However, studies are often confounding and inconclusive for several reasons, such ... Read more >>

J Cardiovasc Dev Dis (Journal of cardiovascular development and disease)
[2021, 8(9):]

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Reply to the Editor-High subthreshold pacing impedance from device-lead connection issues.

Carlo Pignalberi, Marco Valerio Mariani, Antonello Castro, Agostino Piro, Barbara Magris, Bruno Albano, Stefano Aquilani, Michele Magnocavallo, Furio Colivicchi, Francesco Fedele, Carlo Lavalle,

Heart Rhythm (Heart rhythm)
[2021, 18(12):2225-2226]

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Flecainide in Ventricular Arrhythmias: From Old Myths to New Perspectives.

Carlo Lavalle, Sara Trivigno, Giampaolo Vetta, Michele Magnocavallo, Marco Valerio Mariani, Luca Santini, Giovanni Battista Forleo, Massimo Grimaldi, Roberto Badagliacca, Luigi Lanata, Renato Pietro Ricci,

Flecainide is an IC antiarrhythmic drug (AAD) that received in 1984 Food and Drug Administration approval for the treatment of sustained ventricular tachycardia (VT) and subsequently for rhythm control of atrial fibrillation (AF). Currently, flecainide is mainly employed for sinus rhythm maintenance in AF and the treatment of idiopathic ventricular ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(16):]

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Direct oral anticoagulants and chronic kidney disease: it is time to be brave.

Marco Valerio Mariani, Luca Di Lullo, Carlo Lavalle,

J Nephrol (Journal of nephrology)
[2021, 34(5):1419-1420]

Cited: 0 times

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Home delivery of the communicator for remote monitoring of cardiac implantable devices: A multicenter experience during the covid-19 lockdown.

Michele Magnocavallo, Alessia Bernardini, Marco Valerio Mariani, Agostino Piro, Massimiliano Marini, Antonino Nicosia, Carmen Adduci, Antonio Rapacciuolo, Davide Saporito, Stefano Grossi, Giuseppe Santarpia, Paola Vaccaro, Roberto Rordorf, Francesco Pentimalli, Giuseppe Giunta, Monica Campari, Sergio Valsecchi, Carlo Lavalle,

<h4>Background</h4>During the COVID-19 pandemic in-person visits for patients with cardiac implantable electronic devices should be replaced by remote monitoring (RM), in order to prevent viral transmission. A direct home-delivery service of the RM communicator has been implemented at 49 Italian arrhythmia centers.<h4>Methods</h4>According to individual patient preference or the organizational decision ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2021, 44(6):995-1003]

Cited: 3 times

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Sporadic high pacing and shock impedance on remote monitoring in hybrid implantable cardioverter-defibrillator systems: Clinical impact and management.

Carlo Pignalberi, Marco Valerio Mariani, Antonello Castro, Agostino Piro, Barbara Magris, Bruno Albano, Stefano Aquilani, Michele Magnocavallo, Furio Colivicchi, Francesco Fedele, Carlo Lavalle,

<h4>Background</h4>Sporadic high impedance values without other anomalies detected by remote monitoring of hybrid cardiac implantable electronic device systems have been described recently. The clinical significance and related hazard of this phenomenon are not fully understood.<h4>Objective</h4>The purpose of this study was to describe the prevalence, management, and outcomes associated with hybrid ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(8):1292-1300]

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Thromboembolic and Bleeding Risk in Atrial Fibrillation Patients with Chronic Kidney Disease: Role of Anticoagulation Therapy.

Michele Magnocavallo, Antonio Bellasi, Marco Valerio Mariani, Maria Fusaro, Maura Ravera, Ernesto Paoletti, Biagio Di Iorio, Vincenzo Barbera, Domenico Giovanni Della Rocca, Roberto Palumbo, Paolo Severino, Carlo Lavalle, Luca Di Lullo,

Atrial fibrillation (AF) and chronic kidney disease (CKD) are strictly related; several independent risk factors of AF are often frequent in CKD patients. AF prevalence is very common among these patients, ranging between 15% and 20% in advanced stages of CKD. Moreover, the results of several studies showed that AF ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 10(1):]

Cited: 2 times

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Arrhythmic safety of hydroxychloroquine in COVID-19 patients from different clinical settings.

Alessio Gasperetti, Mauro Biffi, Firat Duru, Marco Schiavone, Matteo Ziacchi, Gianfranco Mitacchione, Carlo Lavalle, Ardan Saguner, Antonio Lanfranchi, Giacomo Casalini, Marco Tocci, Davide Fabbricatore, Francesca Salghetti, Marco Valerio Mariani, Mattia Busana, Alfonso Bellia, Chiara Beatrice Cogliati, Pierluigi Viale, Spinello Antinori, Massimo Galli, Nazzareno Galiè, Claudio Tondo, Giovanni Battista Forleo,

<h4>Aims</h4>The aim of the study was to describe ECG modifications and arrhythmic events in COVID-19 patients undergoing hydroxychloroquine (HCQ) therapy in different clinical settings.<h4>Methods and results</h4>COVID-19 patients at seven institutions receiving HCQ therapy from whom a baseline and at least one ECG at 48+ h were available were enrolled in ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2020, 22(12):1855-1863]

Cited: 9 times

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Management of cardiac implantable electronic device follow-up in COVID-19 pandemic: Lessons learned during Italian lockdown.

Agostino Piro, Michele Magnocavallo, Domenico Giovanni Della Rocca, Matteo Neccia, Giovanna Manzi, Marco Valerio Mariani, Martina Straito, Alessia Bernardini, Paolo Severino, Gino Iannucci, Giuseppe Giunta, Cristina Chimenti, Andrea Natale, Francesco Fedele, Carlo Lavalle,

<h4>Introduction</h4>Remote monitoring (RM) has significantly transformed the standard of care for patients with cardiac electronic implantable devices. It provides easy access to valuable information, such as arrhythmic events, acute decompensation manifestations and device-related issues, without the need of in-person visits.<h4>Methods</h4>Starting March 1st, 332 patients were introduced to an RM program ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2020, 31(11):2814-2823]

Cited: 7 times

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Direct oral anticoagulants versus vitamin K antagonists in patients with atrial fibrillation and cancer a meta-analysis.

Marco Valerio Mariani, Michele Magnocavallo, Martina Straito, Agostino Piro, Paolo Severino, Gino Iannucci, Cristina Chimenti, Massimo Mancone, Domenico Giovanni Della Rocca, Giovanni Battista Forleo, Francesco Fedele, Carlo Lavalle,

<h4>Background</h4>Direct oral anticoagulants (DOACs) are recommended as first-line anticoagulants in patients with atrial fibrillation (AF). However, in patients with cancer and AF the efficacy and safety of DOACs are not well established.<h4>Objective</h4>We performed a meta-analysis comparing available data regarding the efficacy and safety of DOACs vs vitamin K antagonists (VKAs) ... Read more >>

J Thromb Thrombolysis (Journal of thrombosis and thrombolysis)
[2021, 51(2):419-429]

Cited: 4 times

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Hospital mortality in decompensated heart failure. A pilot study.

Gianfranco Piccirillo, Federica Moscucci, Marco Valerio Mariani, Claudia Di Iorio, Marcella Fabietti, Fabiola Mastropietri, Davide Crapanzano, Gaetano Bertani, Teresa Sabatino, Giulia Zaccagnini, Ilaria Lospinuso, Pietro Rossi, Damiano Magrì,

<h4>Background/aim</h4>Heart failure is a leading cause of morbidity and mortality worldwide and it is a major cause of emergency department access for cardiovascular disease patients. Aim of this study was to identify the electrocardiographic (ECG) markers, based on short-term temporal repolarization dispersion, capable to individuate decompensated chronic heart failure (CHF) ... Read more >>

J Electrocardiol (Journal of electrocardiology)
[2020, 61:147-152]

Cited: 1 time

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Ischemic Heart Disease and Heart Failure: Role of Coronary Ion Channels.

Paolo Severino, Andrea D'Amato, Mariateresa Pucci, Fabio Infusino, Lucia Ilaria Birtolo, Marco Valerio Mariani, Carlo Lavalle, Viviana Maestrini, Massimo Mancone, Francesco Fedele,

Heart failure is a complex syndrome responsible for high rates of death and hospitalization. Ischemic heart disease is one of the most frequent causes of heart failure and it is normally attributed to coronary artery disease, defined by the presence of one or more obstructive plaques, which determine a reduced ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(9):]

Cited: 22 times

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Toward a Uniform Ablation Protocol for Paroxysmal, Persistent, and Permanent Atrial Fibrillation.

Domenico Giovanni Della Rocca, Carlo Lavalle, Carola Gianni, Marco Valerio Mariani, Sanghamitra Mohanty, Chintan Trivedi, Ugur Canpolat, Bryan MacDonald, Huseyin Ayhan, Agostino Piro, Mohamed Bassiouny, Amin Al-Ahmad, John David Burkhardt, Joseph G Gallinghouse, Rodney P Horton, Javier Sanchez, Nicola Tarantino, Luigi Di Biase, Andrea Natale,

Atrial fibrillation catheter ablation has emerged as the most effective strategy to restore and maintain sinus rhythm. The cornerstone of atrial fibrillation ablation is elimination of triggers from the pulmonary veins by pulmonary vein isolation. Nevertheless, some patients may experience atrial tachyarrhythmia recurrences even with permanent pulmonary vein antral isolation. ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2019, 11(4):731-738]

Cited: 0 times

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Structural and myocardial dysfunction in heart failure beyond ejection fraction.

Paolo Severino, Viviana Maestrini, Marco Valerio Mariani, Lucia Ilaria Birtolo, Rossana Scarpati, Massimo Mancone, Francesco Fedele,

Heart failure is a multifaceted syndrome addressing for a high rate of death among the general population. The common approach to this disease has been always based on the evaluation of the left ventricular ejection fraction by two-dimensional echocardiography with Simpson's method. Mounting evidences have demonstrated the pitfalls of this ... Read more >>

Heart Fail Rev (Heart failure reviews)
[2020, 25(1):9-17]

Cited: 14 times

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Correction to: Structural and myocardial dysfunction in heart failure beyond ejection fraction.

Paolo Severino, Viviana Maestrini, Marco Valerio Mariani, Lucia Ilaria Birtolo, Rossana Scarpati, Massimo Mancone, Francesco Fedele,

The original version of this article unfortunately contained a mistake. ... Read more >>

Heart Fail Rev (Heart failure reviews)
[2020, 25(1):19]

Cited: 1 time

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Advanced Heart Failure and End-Stage Heart Failure: Does a Difference Exist.

Paolo Severino, Paul J Mather, Mariateresa Pucci, Andrea D'Amato, Marco Valerio Mariani, Fabio Infusino, Lucia Ilaria Birtolo, Viviana Maestrini, Massimo Mancone, Francesco Fedele,

Advanced heart failure (AdHF) represents a challenging aspect of heart failure patients. Because of worsening clinical symptoms, high rates of re-hospitalization and mortality, AdHF represents an unstable condition where standard treatments are inadequate and additional interventions must be applied. A heart transplant is considered the optimal therapy for AdHF, but ... Read more >>

Diagnostics (Basel) (Diagnostics (Basel, Switzerland))
[2019, 9(4):]

Cited: 10 times

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Futility in cardiology: the need for a change in perspectives.

Paolo Severino, Marco Valerio Mariani, Francesco Fedele,

Eur J Heart Fail (European journal of heart failure)
[2019, 21(11):1483-1484]

Cited: 9 times

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Arrhythmic Risk in Elderly Patients Candidates to Transcatheter Aortic Valve Replacement: Predictive Role of Repolarization Temporal Dispersion.

Gianfranco Piccirillo, Federica Moscucci, Marcella Fabietti, Ilaria Parrotta, Fabiola Mastropietri, Claudia Di Iorio, Teresa Sabatino, Davide Crapanzano, Giulia Vespignani, Marco Valerio Mariani, Nicolò Salvi, Damiano Magrì,

<h4>Background/aim</h4>Degenerative aortic valve stenosis (AS) is associated to ventricular arrhythmias and sudden cardiac death, as well as mental stress in specific patients. In such a context, substrate, autonomic imbalance as well as repolarization dispersion abnormalities play an undoubted role. Aim of the study was to evaluate the increase of premature ... Read more >>

Front Physiol (Frontiers in physiology)
[2019, 10:991]

Cited: 1 time

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Triggers for Atrial Fibrillation: The Role of Anxiety.

Paolo Severino, Marco Valerio Mariani, Annalisa Maraone, Agostino Piro, Andrea Ceccacci, Lorenzo Tarsitani, Viviana Maestrini, Massimo Mancone, Carlo Lavalle, Massimo Pasquini, Francesco Fedele,

Atrial fibrillation (AF) is the most widely recognized arrhythmia. Systemic arterial hypertension, diabetes, obesity, heart failure, and valvular heart diseases are major risk factors for the onset and progression of AF. Various studies have emphasized the augmented anxiety rate among AF patients due to the poor quality of life; however, ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2019, 2019:1208505]

Cited: 19 times

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Prevention of Cardiovascular Disease: Screening for Magnesium Deficiency.

Paolo Severino, Lucrezia Netti, Marco Valerio Mariani, Annalisa Maraone, Andrea D'Amato, Rossana Scarpati, Fabio Infusino, Mariateresa Pucci, Carlo Lavalle, Viviana Maestrini, Massimo Mancone, Francesco Fedele,

Magnesium is an essential mineral naturally present in the human body, where it acts as cofactor in several enzymatic reactions. Magnesium is a key cardiovascular regulator, which maintains electrical, metabolic, and vascular homeostasis. Moreover, magnesium participates in inflammation and oxidative processes. In fact, magnesium deficiency is involved in the pathophysiology ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2019, 2019:4874921]

Cited: 14 times

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Rivaroxaban in atrial fibrillation cardioversion: an update.

Carlo Lavalle, Martina Straito, Annalisa Caroli, Agostino Piro, Giuseppe Giunta, Marco Valerio Mariani, Francesco Fedele,

Currently, atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, with a prevalence of about 2-3% in the general population, representing a powerful risk factor for stroke and systemic thromboembolism and increased mortality and morbidity. Restoration of sinus rhythm is an important treatment option in AF and has a ... Read more >>

Ther Clin Risk Manag (Therapeutics and clinical risk management)
[2019, 15:613-626]

Cited: 0 times

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Role of surface electrocardiogram in the era of high-resolution mapping and imaging systems-back to the future.

Carlo Lavalle, Marco Valerio Mariani, Domenico Giovanni Della Rocca, Andrea Natale,

J Thorac Dis (Journal of thoracic disease)
[2019, 11(Suppl 3):S307-S310]

Cited: 2 times

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