Full Text Journal Articles by
Author Marco Roffi

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Temporal trends in adoption and outcomes of transcatheter aortic valve implantation: a SwissTAVI Registry analysis.

Stefan Stortecky, Anna Franzone, Dik Heg, David Tueller, Stephane Noble, Thomas Pilgrim, Raban Jeger, Stefan Toggweiler, Enrico Ferrari, Fabian Nietlispach, Maurizio Taramasso, Francesco Maisano, Jürg Grünenfelder, Olivier Muller, Christoph Huber, Marco Roffi, Thierry Carrel, Peter Wenaweser, Stephan Windecker,

AIMS:To describe temporal trends in adoption and performance of transcatheter aortic valve implantation (TAVI) in Switzerland over a period of 5 years. METHODS AND RESULTS:Between 2011 and 2015, a total of 3493 patients were consecutively included in the SwissTAVI Registry (NCT01368250) and analysed for the purpose of this study. The primary ... Read more >>

Eur Heart J Qual Care Clin Outcomes (European heart journal. Quality of care & clinical outcomes)
[2019, 5(3):242-251]

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Influence of intravenous fentanyl compared with morphine on ticagrelor absorption and platelet inhibition in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: rationale and design of the PERSEUS randomized trial.

Sophie Degrauwe, Marco Roffi, Nathalie Lauriers, Olivier Muller, Pier Giorgio Masci, Marco Valgimigli, Juan F Iglesias,

AIMS:Recent evidence demonstrates that intravenous morphine significantly reduces absorption and delays onset of action of oral P2Y12 receptor inhibitors in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). We aimed to assess the influence of intravenous fentanyl compared with morphine on pharmacokinetics and pharmacodynamics of ... Read more >>

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2019, 5(3):158-163]

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Determinants of hospital length of stay after transcatheter aortic valve implantation with self-expanding prostheses: a prospective, single centre observational study.

Angela Frei, Dionysios Adamopoulos, Hajo Müller, Bernhard Walder, Nils Perrin, Thomas Reynaud, Sylvain Ho, Marco Roffi, François Mach, Marc-Joseph Licker, Stéphane Noble,

INTRODUCTION:We sought to identify baseline and periprocedural variables affecting hospital length of stay (LoS) in patients undergoing transcatheter aortic valve implantation (TAVI). METHODS:Data on 304 consecutive patients undergoing TAVI at a single centre between August 2008 and December 2017 were collected prospectively. All patients underwent a complete clinical, echocardiographic and ... Read more >>

Swiss Med Wkly (Swiss medical weekly)
[2019, 149:w20095]

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The hospital results and 1-year outcomes of transcatheter aortic valve-in-valve procedures and transcatheter aortic valve implantations in the native valves: the results from the Swiss-TAVI Registry.

Enrico Ferrari, Stefan Stortecky, Dik Heg, Olivier Muller, Fabian Nietlispach, David Tueller, Stefan Toggweiler, Stéphane Noble, Francesco Maisano, Marco Roffi, Raban Jeger, Jürg Grünenfelder, Christoph Huber, Stephan Windecker, Peter Wenaweser,

OBJECTIVES:The SwissTAVI Registry includes all consecutive patients undergoing transcatheter aortic valve implantation (TAVI) and valve-in-valve (VinV) procedures for a failed bioprosthesis in Switzerland. We report the real world, all-comers, 30-day and 1-year outcomes of patients undergoing VinV and standard TAVI procedures. METHODS:Prospectively collected data from the 2 groups (VinV and ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2019, 56(1):55-63]

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Five-year clinical outcomes and intracoronary imaging findings of the COMFORTABLE AMI trial: randomized comparison of biodegradable polymer-based biolimus-eluting stents with bare-metal stents in patients with acute ST-segment elevation myocardial infarction.

Lorenz Räber, Kyohei Yamaji, Henning Kelbæk, Thomas Engstrøm, Andreas Baumbach, Marco Roffi, Clemens von Birgelen, Masanori Taniwaki, Aris Moschovitis, Serge Zaugg, Miodrag Ostojic, Giovanni Pedrazzini, Dimitrios-Alexios Karagiannis-Voules, Thomas F Lüscher, Ran Kornowski, David Tüller, Vladan Vukcevic, Dik Heg, Stephan Windecker,

AIMS:The long-term outcomes of biolimus-eluting stents (BESs) with biodegradable polymer as compared with bare-metal stent (BMS) in patients with ST-segment elevation myocardial infarction (STEMI) remain unknown. METHODS AND RESULTS:We performed a 5-year clinical follow-up of 1157 patients (BES: N = 575 and BMS: N = 582) included in the randomized COMFORTABLE AMI trial. Serial ... Read more >>

Eur. Heart J. (European heart journal)
[2019, 40(24):1909-1919]

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Roadmap for cardiovascular education across the European Society of Cardiology: inspiring better knowledge and skills, now and for the future.

Dipak Kotecha, Jeroen J Bax, Céline Carrera, Barbara Casadei, Bela Merkely, Stefan D Anker, Panos E Vardas, Peter P Kearney, Marco Roffi, Michelle Ros, Alec Vahanian, Franz Weidinger, Ronen Beeri, Andrzej Budaj, Paolo Calabrò, Katarzyna Czerwińska-Jelonkiewicz, Flavio D'Ascenzi, Tom De Potter, Kevin F Fox, Juha Hartikainen, Brendan McAdam, Davor Milicic, Agnès A Pasquet, Alessandro Sionis, S M Afzal Sohaib, Costas Tsioufis, Patrick M J Verhorst, Paulus Kirchhof, , ,

AIMS:The provision of high-quality education allows the European Society of Cardiology (ESC) to achieve its mission of better cardiovascular practice and provides an essential component of translating new evidence to improve outcomes. METHODS AND RESULTS:The 4th ESC Education Conference, held in Sophia Antipolis (December 2016), brought together ESC education leaders, ... Read more >>

Eur. Heart J. (European heart journal)
[2019, 40(21):1728-1738]

Cited: 1 time

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Patient focus in interventional cardiology: proceedings of the 2018 summit of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) - Nice, France, 20-21 June 2018.

Emanuele Barbato, Josepa Mauri, Robert A Byrne, Marco Roffi, Donna Fitzsimons, Gabor Toth, Davide Capodanno, Julinda Mehilli, Anna Sonia Petronio, Alaide Chieffo, Panos Vardas, Christoph K Naber, Dariusz Dudek, Michael Haude, Andreas Baumbach,

EuroIntervention (EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology)
[2019, 14(17):1720-1723]

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Percutaneous Coronary Intervention of Chronic Total Occlusions in Patients with Diabetes Mellitus: a Treatment-Risk Paradox.

Juan F Iglesias, Sophie Degrauwe, Fabio Rigamonti, Stéphane Noble, Marco Roffi,

PURPOSE OF REVIEW:Diabetes mellitus (DM) is highly prevalent among patients undergoing percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs). This review aims to summarize the available evidence on CTO recanalization in patients with DM. RECENT FINDINGS:Coronary artery bypass grafting (CABG) surgery is the recommended revascularization modality for patients with ... Read more >>

Curr Cardiol Rep (Current cardiology reports)
[2019, 21(2):9]

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Minimizing Distal Embolization During Carotid Artery Stenting.

Debabrata Mukherjee, Marco Roffi,

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2019, 12(4):404-405]

Cited: 0 times

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2018 ESC/EACTS Guidelines on myocardial revascularization.

Miguel Sousa-Uva, Franz-Josef Neumann, Anders Ahlsson, Fernando Alfonso, Adrian P Banning, Umberto Benedetto, Robert A Byrne, Jean-Philippe Collet, Volkmar Falk, Stuart J Head, Peter Jüni, Adnan Kastrati, Akos Koller, Steen D Kristensen, Josef Niebauer, Dimitrios J Richter, Petar M Seferovic, Dirk Sibbing, Giulio G Stefanini, Stephan Windecker, Rashmi Yadav, Michael O Zembala, ,

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2019, 55(1):4-90]

Cited: 10 times

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Fourth universal definition of myocardial infarction (2018).

Kristian Thygesen, Joseph S Alpert, Allan S Jaffe, Bernard R Chaitman, Jeroen J Bax, David A Morrow, Harvey D White, ,

Eur. Heart J. (European heart journal)
[2019, 40(3):237-269]

Cited: 16 times

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2018 ESC/EACTS Guidelines on myocardial revascularization.

Franz-Josef Neumann, Miguel Sousa-Uva, Anders Ahlsson, Fernando Alfonso, Adrian P Banning, Umberto Benedetto, Robert A Byrne, Jean-Philippe Collet, Volkmar Falk, Stuart J Head, Peter Jüni, Adnan Kastrati, Akos Koller, Steen D Kristensen, Josef Niebauer, Dimitrios J Richter, Petar M Seferovic, Dirk Sibbing, Giulio G Stefanini, Stephan Windecker, Rashmi Yadav, Michael O Zembala, ,

Eur. Heart J. (European heart journal)
[2019, 40(2):87-165]

Cited: 39 times

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Integrating the results of the CULPRIT-SHOCK trial in the 2017 ESC ST-elevation myocardial infarction guidelines: viewpoint of the task force.

Borja Ibanez, Sigrun Halvorsen, Marco Roffi, Héctor Bueno, Holger Thiele, Pascal Vranckx, Franz-Josef Neumann, Stephan Windecker, Stefan James,

Eur. Heart J. (European heart journal)
[2018, 39(48):4239-4242]

Cited: 2 times

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Changes in Coronary Plaque Composition in Patients With Acute Myocardial Infarction Treated With High-Intensity Statin Therapy (IBIS-4): A Serial Optical Coherence Tomography Study.

Lorenz Räber, Konstantinos C Koskinas, Kyohei Yamaji, Masanori Taniwaki, Marco Roffi, Lene Holmvang, Hector M Garcia Garcia, Thomas Zanchin, Rafaela Maldonado, Aris Moschovitis, Giovanni Pedrazzini, Serge Zaugg, Jouke Dijkstra, Christian M Matter, Patrick W Serruys, Thomas F Lüscher, Henning Kelbaek, Alexios Karagiannis, Maria D Radu, Stephan Windecker,

OBJECTIVES:This study assessed changes in optical coherence tomography (OCT)-defined plaque composition in patients with ST-elevation myocardial infarction (STEMI) receiving high-intensity statin treatment. BACKGROUND:OCT is a high-resolution modality capable of measuring plaque characteristics including fibrous cap thickness (FCT) and macrophage infiltration. There is limited in vivo evidence regarding the effects of statins ... Read more >>

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2019, 12(8 Pt 1):1518-1528]

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Multisite vascular disease in acute coronary syndromes: increased in-hospital mortality and no improvement over time.

Marco Roffi, Dragana Radovanovic, Juan F Iglesias, Franz R Eberli, Philip Urban, Giovanni B Pedrazzini, Paul Erne, Hans Rickli,

Limited data are available on the impact of multisite artery disease in patients with acute coronary syndromes. In particular, it is unknown whether the outcomes of those high-risk patients have improved over time. Therefore, we addressed the multisite artery disease patient population enrolled in the Swiss nationwide prospective acute coronary ... Read more >>

Eur Heart J Acute Cardiovasc Care (European heart journal. Acute cardiovascular care)
[2018, :2048872618814708]

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Design and rationale of the Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Standard DAPT Regimen (MASTER DAPT) Study.

Enrico Frigoli, Pieter Smits, Pascal Vranckx, Yokio Ozaki, Jan Tijssen, Peter Jüni, Marie-Claude Morice, Yoshinobu Onuma, Stephan Windecker, Andrè Frenk, Christian Spaulding, Bernard Chevalier, Emanuele Barbato, Pim Tonino, David Hildick-Smith, Marco Roffi, Ran Kornowski, Carl Schultz, Maciej Lesiak, Andrés Iñiguez, Antonio Colombo, Mirvat Alasnag, Ajit Mullasari, Stefan James, Goran Stankovic, Paul J L Ong, Alfredo E Rodriguez, Felix Mahfoud, Jozef Bartunek, Aris Moschovitis, Peep Laanmets, Sergio Leonardi, Dik Heg, Mikael Sunnåker, Marco Valgimigli,

BACKGROUND:The optimal duration of antiplatelet therapy in high-bleeding risk (HBR) patients with coronary artery disease treated with newer-generation drug-eluting bioresorbable polymer-coated stents remains unclear. DESIGN:MASTER DAPT (clinicaltrial.govNCT03023020) is an investigator-initiated, open-label, multicenter, randomized controlled trial comparing an abbreviated versus a standard duration of antiplatelet therapy after bioresorbable polymer-coated Ultimaster (TANSEI) ... Read more >>

Am. Heart J. (American heart journal)
[2019, 209:97-105]

Cited: 0 times

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Treatment-risk paradox in acute coronary syndromes.

Marco Roffi, Debabrata Mukherjee,

Eur. Heart J. (European heart journal)
[2018, 39(42):3807-3809]

Cited: 0 times

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Impact of angiographic coronary artery disease complexity on ischemic and bleeding risks and on the comparative effectiveness of zotarolimus-eluting vs. bare-metal stents in uncertain drug-eluting stent candidates.

Giuseppe Gargiulo, Athanasios Patialiakas, Raffaele Piccolo, Attila Thury, Salvatore Colangelo, Gianluca Campo, Matteo Tebaldi, Imre Ungi, Stefano Tondi, Marco Roffi, Alberto Menozzi, Nicoletta de Cesare, Roberto Garbo, Emanuele Meliga, Luca Testa, Henrique Mesquita Gabriel, Marco Ferlini, Francesco Liistro, Antonio Dellavalle, Pascal Vranckx, Carlo Briguori, Stephan Windecker, Marco Valgimigli,

BACKGROUND:The impact of coronary artery disease (CAD) extension/complexity on outcomes and on the comparative benefits/risks of zotarolimus-eluting stent (ZES) versus bare-metal stents (BMS) remains unclear in patients at high risk of bleeding or thrombosis or at low restenosis risk. METHODS:We performed a post-hoc analysis of the ZEUS trial. The impact ... Read more >>

Int. J. Cardiol. (International journal of cardiology)
[2019, 277:60-65]

Cited: 0 times

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2018 ESC/ESH Guidelines for the management of arterial hypertension.

Bryan Williams, Giuseppe Mancia, Wilko Spiering, Enrico Agabiti Rosei, Michel Azizi, Michel Burnier, Denis L Clement, Antonio Coca, Giovanni de Simone, Anna Dominiczak, Thomas Kahan, Felix Mahfoud, Josep Redon, Luis Ruilope, Alberto Zanchetti, Mary Kerins, Sverre E Kjeldsen, Reinhold Kreutz, Stephane Laurent, Gregory Y H Lip, Richard McManus, Krzysztof Narkiewicz, Frank Ruschitzka, Roland E Schmieder, Evgeny Shlyakhto, Costas Tsioufis, Victor Aboyans, Ileana Desormais, ,

Eur. Heart J. (European heart journal)
[2018, 39(33):3021-3104]

Cited: 80 times

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Prognostic Value of SYNTAX Score II in Patients with Acute Coronary Syndromes Referred for Invasive Management: A Subanalysis from the SPUM and COMFORTABLE AMI Cohorts.

Slayman Obeid, Antonio H Frangieh, Lorenz Räber, Nooraldaem Yousif, Thomas Gilhofer, Kyohei Yamaji, Milosz Jaguszewski, Soheila Aghlmandi, James Adams, Yannik Bockhorn, Christian Templin, Barbara E Stähli, Peter Jüni, Nicolas Rodondi, François Mach, Marco Roffi, Stephan Windecker, Willibald Maier, Fabian Nietlispach, Christian M Matter, Roland Klingenberg, Thomas F Lüscher,

Aims:To assess the incremental prognostic value of SYNTAX score II (SxSII) as compared to anatomical SYNTAX Score (SxS) and GRACE risk score in patients with acute coronary syndromes who underwent percutaneous coronary intervention. Methods and results:SxSII and SxS were determined in 734 ACS patients. Patients were enrolled in the prospective ... Read more >>

Cardiol Res Pract (Cardiology Research and Practice)
[2018, 2018:9762176]

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Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial.

Pascal Vranckx, Marco Valgimigli, Peter Jüni, Christian Hamm, Philippe Gabriel Steg, Dik Heg, Gerrit Anne van Es, Eugene P McFadden, Yoshinobu Onuma, Cokky van Meijeren, Ply Chichareon, Edouard Benit, Helge Möllmann, Luc Janssens, Maurizio Ferrario, Aris Moschovitis, Aleksander Zurakowski, Marcello Dominici, Robert Jan Van Geuns, Kurt Huber, Ton Slagboom, Patrick W Serruys, Stephan Windecker, ,

BACKGROUND:We hypothesised that ticagrelor, in combination with aspirin for 1 month, followed by ticagrelor alone, improves outcomes after percutaneous coronary intervention compared with standard antiplatelet regimens. METHODS:GLOBAL LEADERS was a randomised, open-label superiority trial at 130 sites in 18 countries. Patients undergoing percutaneous coronary intervention with a biolimus A9-eluting stent ... Read more >>

Lancet (Lancet (London, England))
[2018, 392(10151):940-949]

Cited: 5 times

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Ultrathin-strut, biodegradable-polymer, sirolimus-eluting stents versus thin-strut, durable-polymer, everolimus-eluting stents for percutaneous coronary revascularisation: 5-year outcomes of the BIOSCIENCE randomised trial.

Thomas Pilgrim, Raffaele Piccolo, Dik Heg, Marco Roffi, David Tüller, Olivier Muller, Igal Moarof, George C M Siontis, Stéphane Cook, Daniel Weilenmann, Christoph Kaiser, Florim Cuculi, Lukas Hunziker, Franz R Eberli, Peter Jüni, Stephan Windecker,

BACKGROUND:Drug-eluting stents combining an ultrathin cobalt-chromium stent platform with a biodegradable polymer eluting sirolimus have been shown to be non-inferior or superior to thin-strut, durable-polymer, everolimus-eluting stents in terms of 1 year safety and efficacy outcomes. METHODS:In the randomised, single-blind, multicentre, non-inferiority BIOSCIENCE trial, we compared biodegradable-polymer sirolimus-eluting stents with ... Read more >>

Lancet (Lancet (London, England))
[2018, 392(10149):737-746]

Cited: 1 time

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2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy.

Vera Regitz-Zagrosek, Jolien W Roos-Hesselink, Johann Bauersachs, Carina Blomström-Lundqvist, Renata Cífková, Michele De Bonis, Bernard Iung, Mark Richard Johnson, Ulrich Kintscher, Peter Kranke, Irene Marthe Lang, Joao Morais, Petronella G Pieper, Patrizia Presbitero, Susanna Price, Giuseppe M C Rosano, Ute Seeland, Tommaso Simoncini, Lorna Swan, Carole A Warnes, ,

Eur. Heart J. (European heart journal)
[2018, 39(34):3165-3241]

Cited: 9 times

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A giant coronary artery aneurysm associated with multiple peripheral arterial aneurysms and an abdominal aortic aneurysm.

Kamran Ahmadov, Tornike Sologashvili, Marco Roffi, Christoph Huber,

We report a rare association of a giant aneurysm of the left circumflex coronary artery with multiple peripheral arterial aneurysms and an abdominal aortic aneurysm in a 70-year-old patient. The exclusion of the giant circumflex artery aneurysm was performed successfully by proximal and distal ligation of all branches and bypass ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2018, 54(3):598-600]

Cited: 0 times

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Commentary: The Long and Winding Road.

Roberto Lorenzoni, Marco Roffi,

J. Endovasc. Ther. (Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists)
[2018, 25(5):608-610]

Cited: 0 times

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