Full Text Journal Articles by
Author Marcel A Verhoff

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Postmortem fluorescence angiography of the explanted human heart.

Constantin Lux, Miriam Klinger, Patrick Sauer, Marcel A Verhoff, Mattias Kettner,

Within the scope of this technical report, the feasibility of indocyanine green (ICG) as a fluorescent agent for postmortem angiography of the heart is tested. The study included 4 deceased persons with no respective medical history of heart diseases. The basic patterns of findings in ICG fluorescence angiography associated with ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2021, :]

Cited: 0 times

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Assessment of renal glomerulosclerosis and thickness of the carotid intima-media complex as a means of age estimation in Western European bodies.

Carl Daniel Lehmann-Leo, Frank Ramsthaler, Christoph G Birngruber, Marcel A Verhoff,

<h4>Introduction</h4>The estimation of age-at-death of unidentified cadavers is a central aspect of the identification process. With increasing age, the incidence of glomerulosclerosis and the thickness of the carotid wall have been observed to also increase. This correlation has been demonstrated in various international histological studies. The aim of our study ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2021, :]

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It is all about the insects: a retrospective on 20 years of forensic entomology highlights the importance of insects in legal investigations.

Lena Lutz, Richard Zehner, Marcel A Verhoff, Hansjürgen Bratzke, Jens Amendt,

This study highlights the importance of insect evidence by evaluating 949 insect-associated cases, including 139 entomological reports, from 2001 to 2019 at the Institute of Legal Medicine Frankfurt/Germany. With a high number of cases in the summer months and a low number in the colder season, 78.5% of the bodies ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2021, 135(6):2637-2651]

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[Infectiousness of SARS-CoV-2 positive corpses during external post mortem examination].

Marcel A Verhoff, Klaus Püschel, Benjamin Ondruschka,

MMW Fortschr Med (MMW Fortschritte der Medizin)
[2021, 163(12):56-58]

Cited: 0 times

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Genetic analysis of sudden unexpected death cases: Evaluation of library preparation methods to handle heterogeneous sample material.

Stefanie Scheiper-Welling, Stephanie Körber, Christof Geisen, Marcel A Verhoff, Silke Kauferstein,

Over the past years, next-generation sequencing (NGS) technologies revolutionized the possibilities in a broad range of application areas. Also in the field of forensic genetics, NGS continuously gained in importance and attentiveness. A significant number of sudden cardiac deaths (SCD) in the young is due to heritable arrhythmia syndromes emphasizing ... Read more >>

Forensic Sci Int (Forensic science international)
[2021, 322:110768]

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To Be There or Not to Be There, That Is the Question-On the Problem of Delayed Sampling of Entomological Evidence.

Lena Lutz, Marcel A Verhoff, Jens Amendt,

The aim of the current study was to analyze two major pitfalls in forensic entomological casework: delayed evidence sampling and the effect of low-temperature storage of the body. For this purpose, temperature profiles of heavily infested corpses during cooling and cases in which insect evidence was collected both at the ... Read more >>

Insects (Insects)
[2021, 12(2):]

Cited: 4 times

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Post-mortem genetic investigation of cardiac disease-associated genes in sudden infant death syndrome (SIDS) cases.

Jasmin Köffer, Stefanie Scheiper-Welling, Marcel A Verhoff, Thomas Bajanowski, Silke Kauferstein,

The sudden infant death syndrome (SIDS) is one of the leading causes of postneonatal infant death. It has been shown that there exists a complex relationship between SIDS and inherited cardiac disease. Next-generation sequencing and surveillance of cardiac channelopathy and cardiomyopathy genes represent an important tool for investigating the cause ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2021, 135(1):207-212]

Cited: 3 times

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Mongolian spots as a finding in forensic examinations of possible child abuse-implications for case work.

Mattias Kettner, Christoph G Birngruber, Constanze Niess, Marco Baz-Bartels, Lena Bunzel, Marcel A Verhoff, Constantin Lux, Frank Ramsthaler,

Mongolian spots (MS) are congenital dermal conditions resulting from neural crest-derived melanocytes migration to the skin during embryogenesis. MS incidences are highly variable in different populations. Morphologically, MS present as hyperpigmented maculae of varying size and form, ranging from round spots of 1 cm in diameter to extensive discolorations covering ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2020, 134(3):1141-1148]

Cited: 1 time

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Feasibility of an accelerated PVAL method for the collection of GSR and biological traces.

Constantin Lux, Lucy Taube, Marcel A Verhoff, Sonja Kurscheid, Gabriele Zöller-Huse, Stephan Welkerling, Rüdiger Schumacher, Dieter Neimke, Mattias Kettner,

The polyvinyl alcohol method (PVAL) is known as an effective technique to thoroughly collect traces of gunshot residue (GSR) from different surfaces, e.g., from hands or gunshot wounds. Despite obvious advantages over other methods using adhesive tapes, PVAL is still not widely accepted and applied in routine case work due ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2020, 134(3):1051-1059]

Cited: 0 times

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Definitions of frontal bone inclination: Applicability and quantification.

Sarah C Koelzer, Ines V Kuemmel, Jan T Koelzer, Frank Ramsthaler, Franziska Holz, Axel Gehl, Marcel A Verhoff,

In sex determination from crania, a "vertical" forehead is considered a female feature, while a "sloping" forehead is considered a male feature. Precise description of frontal inclination with a quantitative measure like an angle is considerably more difficult as it requires accurate identification of clearly defined craniometric points. In the ... Read more >>

Forensic Sci Int (Forensic science international)
[2019, 303:109929]

Cited: 1 time

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Letter to the editor regarding "Undetected traumatic diastasis of cranial sutures in a case of child abuse" by C.P. Campobasso et al. (https://doi.org/10.1016/j.forsciint.2019.03.011).

Christoph G Birngruber, Franziska Holz, Marcel A Verhoff,

Forensic Sci Int (Forensic science international)
[2019, 304:109954]

Cited: 0 times

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Non-Natural Death Associated with Sexual Activity: Results of a 25-Year Medicolegal Postmortem Study.

Lena Bunzel, Sarah C Koelzer, Barbara Zedler, Marcel A Verhoff, Markus Parzeller,

<h4>Introduction</h4>Non-natural deaths associated with sexual activity may occur either with or without the involvement of other persons.<h4>Aim</h4>The present study provides an overview of cases of non-natural death related to sexual activities as well as recommendations of how to handle these cases and to identify potentially dangerous pleasure-enhancing techniques.<h4>Methods</h4>This medicolegal, postmortem, ... Read more >>

J Sex Med (The journal of sexual medicine)
[2019, 16(10):1547-1556]

Cited: 3 times

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Increased inducible nitric oxide synthase (iNOS) expression in human myocardial infarction.

Verena Wilmes, Stefanie Scheiper, Winta Roehr, Constanze Niess, Stefan Kippenberger, Katja Steinhorst, Marcel A Verhoff, Silke Kauferstein,

Increased inducible nitric oxide synthase (iNOS) expression has been reported in heart failure, cardiomyopathies, and arteriosclerosis. iNOS is expressed in the heart upon inflammatory stimuli and produces excessive amounts of nitric oxide (NO). The overproduction of NO is cytotoxic and involved in cardiovascular diseases. Furthermore, iNOS produces superoxide anion which ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2020, 134(2):575-581]

Cited: 4 times

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Is Irreversible Loss of Brain Function a Reliable Sign of Death?

Markus Parzeller, Marcel A Verhoff, Barbara Zedler,

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2019, 116(6):98]

Cited: 0 times

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Correction to: Myiasis in humans-a global case report evaluation and literature analysis.

Victoria Bernhardt, Fabian Finkelmeier, Marcel A Verhoff, Jens Amendt,

It was brought to the authors' attention that a citation within the published article was cited incorrectly. ... Read more >>

Parasitol Res (Parasitology research)
[2019, 118(2):723]

Cited: 0 times

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Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas.

Pia S Zeiner, Corinna Preusse, Anna Golebiewska, Jenny Zinke, Ane Iriondo, Arnaud Muller, Tony Kaoma, Katharina Filipski, Monika Müller-Eschner, Simon Bernatz, Anna-Eva Blank, Peter Baumgarten, Elena Ilina, Anne Grote, Martin L Hansmann, Marcel A Verhoff, Kea Franz, Friedrich Feuerhake, Joachim P Steinbach, Jörg Wischhusen, Werner Stenzel, Simone P Niclou, Patrick N Harter, Michel Mittelbronn,

While the central nervous system is considered an immunoprivileged site and brain tumors display immunosuppressive features, both innate and adaptive immune responses affect glioblastoma (GBM) growth and treatment resistance. However, the impact of the major immune cell population in gliomas, represented by glioma-associated microglia/macrophages (GAMs), on patients' clinical course is ... Read more >>

Brain Pathol (Brain pathology (Zurich, Switzerland))
[2019, 29(4):513-529]

Cited: 29 times

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A molecular, morphological, and physiological comparison of English and German populations of Calliphora vicina (Diptera: Calliphoridae).

Kwankamol Limsopatham, Martin J R Hall, Richard Zehner, Barbara K Zajac, Marcel A Verhoff, Narin Sontigun, Kom Sukontason, Kabkaew L Sukontason, Jens Amendt,

The bluebottle blow fly Calliphora vicina is a common species distributed throughout Europe that can play an important role as forensic evidence in crime investigations. Developmental rates of C. vicina from distinct populations from Germany and England were compared under different temperature regimes to explore the use of growth data ... Read more >>

PLoS One (PloS one)
[2018, 13(12):e0207188]

Cited: 4 times

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Myiasis in humans-a global case report evaluation and literature analysis.

Victoria Bernhardt, Fabian Finkelmeier, Marcel A Verhoff, Jens Amendt,

Myiasis refers to the infestation of living humans and vertebrates with fly larvae that feed on necrotic or vital tissue of the host. Since the invasion of new fly species in Europe is currently being observed, which live obligatorily parasitically or are close relatives of such species, the aim of ... Read more >>

Parasitol Res (Parasitology research)
[2019, 118(2):389-397]

Cited: 5 times

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Sudden unexpected death in the young - Value of massive parallel sequencing in postmortem genetic analyses.

Stefanie Scheiper, Eva Ramos-Luis, Alejandro Blanco-Verea, Constanze Niess, Britt-Maria Beckmann, Ulrike Schmidt, Mattias Kettner, Christof Geisen, Marcel A Verhoff, Maria Brion, Silke Kauferstein,

Cases of sudden cardiac death (SCD) in young and apparently healthy individuals represent a devastating event in affected families. Hereditary arrhythmia syndromes, which include primary electrical heart disorders as well as cardiomyopathies, are known to contribute to a significant number of these sudden death cases. We performed postmortem genetic analyses ... Read more >>

Forensic Sci Int (Forensic science international)
[2018, 293:70-76]

Cited: 3 times

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Environmental factors influencing flight activity of forensically important female blow flies in Central Europe.

Lena Lutz, Marcel A Verhoff, Jens Amendt,

In forensic entomology, evaluation of a possible delay between a person's death and insect colonization is crucial. We monitored the seasonal flight activities of the most abundant blow flies in an urban habitat in Frankfurt/Germany based on 152 sampling days between April and October 2017. Thirty-six thousand female specimens of ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2019, 133(4):1267-1278]

Cited: 7 times

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Fatalities of stowaways traveling in airplane wheel wells.

Stefanie Plenzig, Hannelore Held, Franziska Holz, Theresa Kals, Marcel A Verhoff,

The earliest mention of a stowaway in the wheel well of an airplane dates back to 1947: A 30-year-old man chose this mode of travel for a trip from Lisbon to Brazil and survived (Véronneau et al., 1996). In a retrospective study, we evaluated cases with lethal outcome of stowaways ... Read more >>

Forensic Sci Int (Forensic science international)
[2018, 290:11-15]

Cited: 0 times

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Dating Pupae of the Blow Fly Calliphora vicina Robineau-Desvoidy 1830 (Diptera: Calliphoridae) for Post Mortem Interval-Estimation: Validation of Molecular Age Markers.

Barbara K Zajac, Jens Amendt, Marcel A Verhoff, Richard Zehner,

Determining the age of juvenile blow flies is one of the key tasks of forensic entomology when providing evidence for the minimum post mortem interval. While the age determination of blow fly larvae is well established using morphological parameters, the current study focuses on molecular methods for estimating the age ... Read more >>

Genes (Basel) (Genes)
[2018, 9(3):]

Cited: 4 times

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Morphometric investigations to assess the compatibility of mandible and skull.

Sandra Preissler, Marcel A Verhoff, Frank Ramsthaler, Franziska Holz, Axel Gehl, Sarah C Koelzer,

When a morphologically separated skull and mandible are found in the same case context, the possibility of a match arises. Two criteria with which to determine a match are the rough articulation between the mandibular condyles and cranial base itself and, most importantly, the fit of the teeth. However, when ... Read more >>

Forensic Sci Int (Forensic science international)
[2018, 286:193-198]

Cited: 1 time

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Species diversity and tissue specific dispersal of necrophagous Diptera on human bodies.

Victoria Bernhardt, Miklós Bálint, Marcel A Verhoff, Jens Amendt,

In forensic entomology, many studies analyze fly activity and succession on dead bodies by using pig cadavers and a variety of small baited traps. Data on real human bodies are very rare. To address this shortcoming, we analyzed the fly fauna of 51 human bodies in Germany. Sex, age, place ... Read more >>

Forensic Sci Med Pathol (Forensic science, medicine, and pathology)
[2018, 14(1):76-84]

Cited: 6 times

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Influence of genetic modifiers on sudden cardiac death cases.

Tina Jenewein, Thomas Neumann, Damir Erkapic, Malte Kuniss, Marcel A Verhoff, Gerhard Thiel, Silke Kauferstein,

Sequence variants in the ion channel genes KCNH2 and SCN5A may cause the cardiac disorder long QT syndrome (LQTS). This disorder is associated with incomplete penetrance and variable expression in KCNH2- or SCN5A-mutation carriers. Common genetic variants, if associated with a mutation, may affect the severity of this cardiac disorder. ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2018, 132(2):379-385]

Cited: 5 times

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