Full Text Journal Articles by
Author Marc Lazzaro

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Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.

S Claiborne Johnston, J Donald Easton, Mary Farrant, William Barsan, Robin A Conwit, Jordan J Elm, Anthony S Kim, Anne S Lindblad, Yuko Y Palesch, ,

BACKGROUND:Combination antiplatelet therapy with clopidogrel and aspirin may reduce the rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient ischemic attack (TIA). A trial of combination antiplatelet therapy in a Chinese population has shown a reduction in the risk of recurrent stroke. We ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2018, 379(3):215-225]

Cited: 19 times

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Safety and Efficacy of a 3-Dimensional Stent Retriever With Aspiration-Based Thrombectomy vs Aspiration-Based Thrombectomy Alone in Acute Ischemic Stroke Intervention: A Randomized Clinical Trial.

Raul G Nogueira, Donald Frei, Jawad F Kirmani, Osama Zaidat, Demetrius Lopes, Aquilla S Turk, Donald Heck, Brian Mason, Diogo C Haussen, Elad I Levy, Siddhart Mehta, Marc Lazzaro, Michael Chen, Arnd Dörfler, Albert J Yoo, Colin P Derdeyn, Lee Schwamm, David Langer, Adnan Siddiqui, ,

Importance:The treatment effects of individual mechanical thrombectomy devices in large-vessel acute ischemic stroke (AIS) remain unclear. Objective:To determine whether the novel 3-dimensional (3-D) stent retriever used in conjunction with an aspiration-based mechanical thrombectomy device (Penumbra System; Penumbra) is noninferior to aspiration-based thrombectomy alone in AIS. Design, Setting, and Participants:This randomized, ... Read more >>

JAMA Neurol (JAMA neurology)
[2018, 75(3):304-311]

Cited: 4 times

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Cross-circulation thrombectomy with use of a stent retriever: A case report.

Ali Sultan-Qurraie, Gregory Rozansky, John Andrew Cox, Marc Lazzaro,

Introduction The efficacy of the endovascular treatment of acute ischemic stroke has been substantiated by several recent randomized clinical trials. While intra-arterial therapy has significantly evolved in recent years, anatomic cerebrovascular variants and disease burden can present challenges to timely recanalization. We present the first reported case of anterior-to-posterior mechanical ... Read more >>

Interv Neuroradiol (Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences)
[2017, 23(4):422-426]

Cited: 0 times

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Consecutive Endovascular Treatment of 20 Ruptured Very Small (<3 mm) Anterior Communicating Artery Aneurysms.

Kaiz S Asif, Ahsan Sattar, Marc A Lazzaro, Brian-Fred Fitzsimmons, John R Lynch, Osama O Zaidat,

Small aneurysms located at the anterior communicating artery carry significant procedural challenges due to a complex anatomy. Recent advances in endovascular technologies have expanded the use of coil embolization for small aneurysm treatment. However, limited reports describe their safety and efficacy profiles in very small anterior communicating artery aneurysms.We sought ... Read more >>

Interv Neurol (Interventional neurology)
[2016, 5(1-2):57-64]

Cited: 1 time

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Stenting and angioplasty for idiopathic intracranial hypertension: a case series with clinical, angiographic, ophthalmological, complication, and pressure reporting.

Mohamed S Teleb, Matthew E Cziep, Mohammad Issa, Marc Lazzaro, Kaiz Asif, Sang Hun Hong, John R Lynch, Brian-Fred M Fitzsimmons, Bernd F Remler, Osama O Zaidat,

BACKGROUND: Previous studies have demonstrated that cerebral dural sinus stenosis (DSS) may be a potential patho-physiological cause of idiopathic intracranial hypertension (IIH). Endovascular therapy for DSS is emerging as a potential alternative to treat IIH. Here, we present the results of our case series. METHOD: We prospectively collected angiographic and ... Read more >>

J Neuroimaging (Journal of neuroimaging : official journal of the American Society of Neuroimaging)
[2015, 25(1):72-80]

Cited: 10 times

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Predictors and Outcomes Associated with Rescue Therapy in SWIFT.

Marc A Lazzaro, Osama O Zaidat, Jeffrey L Saver, ,

In the Solitaire With the Intention For Thrombectomy (SWIFT) trial, rescue therapy was used when the Solitaire or Merci device was unable to restore vessel patency. Markers for nonrecanalization in acute stroke have been reported for intravenous tissue plasminogen activator; however, similar predictors are not known for endovascular therapy. We ... Read more >>

Interv Neurol (Interventional neurology)
[2014, 2(4):178-182]

Cited: 0 times

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Stenting and angioplasty of small cerebral arteries in symptomatic intracranial atherosclerotic disease.

Osama O Zaidat, Junaid Kalia, Emad Nourollah-Zadeh, Alicia Castonguay, Marc Lazzaro, John Lynch, Brian-Fred Fitzsimmons,

Intracranial atherosclerotic disease (ICAD) is a common cause of stroke with a poor natural history despite medical therapy. Few studies have investigated endovascular therapies for the treatment of symptomatic ICAD in distal intracranial arteries. Here, we present the feasibility and safety of balloon angioplasty with and without stenting in patients ... Read more >>

Interv Neurol (Interventional neurology)
[2014, 2(3):123-131]

Cited: 2 times

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Endovascular reconstruction for progressively worsening carotid artery dissection.

Kaiz S Asif, Marc A Lazzaro, Mohamed S Teleb, Brian-Fred Fitzsimmons, John Lynch, Osama Zaidat,

Carotid artery dissection is an important cause of stroke in young patients. Selection criteria for endovascular repair have not been well defined and limited data exist on long-term outcomes of stent reconstruction.To report the immediate and long-term clinical and radiographic outcomes of patients treated with stent placement for progressively worsening ... Read more >>

J Neurointerv Surg (Journal of neurointerventional surgery)
[2015, 7(1):32-39]

Cited: 3 times

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Identifying delays to mechanical thrombectomy for acute stroke: onset to door and door to clot times.

Kaiz S Asif, Marc A Lazzaro, Osama Zaidat,

Outcomes from endovascular therapy for acute stroke are time dependent. Delays in the administration of this therapy have not been extensively studied and no performance benchmarks have been established. There are limited data on the complex factors that can affect these delays. In this review, we discuss the existing literature ... Read more >>

J Neurointerv Surg (Journal of neurointerventional surgery)
[2014, 6(7):505-510]

Cited: 6 times

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Cerebral arteriovenous malformation diagnosis and management.

Kaiz Asif, John Leschke, Marc A Lazzaro,

Arteriovenous malformations of the brain can carry considerable morbidity and mortality in the setting of rupture. The complex angioarchitecture and hemodynamic alteration requires careful consideration in diagnostic and management approaches. In this review, the authors define the pathophysiology, outline diagnostic methods, and highlight current management approaches. ... Read more >>

Semin Neurol (Seminars in neurology)
[2013, 33(5):468-475]

Cited: 1 time

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Demand-supply of neurointerventionalists for endovascular ischemic stroke therapy.

Osama O Zaidat, Marc A Lazzaro, Italo Linfante, Thanh Nguyen, Nazli Janjua,

Neurology (Neurology)
[2013, 81(3):305-306]

Cited: 2 times

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Safety and predictors of aneurysm retreatment for remnant intracranial aneurysm after initial endovascular embolization.

Mohamed S Teleb, Dhruvil J Pandya, Alicia C Castonguay, Gerald Eckardt, Rochelle Sweis, Marc A Lazzaro, Mohammed A Issa, Brian-Fred Fitzsimmons, John R Lynch, Osama O Zaidat,

INTRODUCTION: Aneurysmal subarachnoid hemorrhage (SAH) is a rare but devastating form of stroke. Endovascular therapy has been criticized for its higher rate of recanalization and retreatment. The safety and predictors of retreatment are unknown. We report the clinical outcomes, imaging outcomes and predictors for aneurysm retreatment after initial endovascular embolization. ... Read more >>

J Neurointerv Surg (Journal of neurointerventional surgery)
[2014, 6(7):490-494]

Cited: 8 times

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'Time' for success.

Osama O Zaidat, Marc A Lazzaro, Rishi Gupta, Peter A Rasmussen, Donald F Frei, Mayank Goyal,

J Neurointerv Surg (Journal of neurointerventional surgery)
[2013, 5(5):391-392]

Cited: 4 times

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Angiographic lumen changes associated with oversized intracranial stent implantation for aneurysm treatment.

Marc A Lazzaro, Mohamed S Teleb, Osama O Zaidat,

BACKGROUND: The effect of oversized intracranial stent implantation, and potential excessive neointimal hyperplasia from the chronic outward radial force, has not been reported. We sought to compare the angiographic narrowing associated with implantation of oversized stents. METHODS: We reviewed an aneurysm database and identified patients treated with stent-assisted embolization involving ... Read more >>

J Neuroimaging (Journal of neuroimaging : official journal of the American Society of Neuroimaging)
[2013, 23(4):508-513]

Cited: 0 times

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Idiopathic Intracranial Hypertension. A Systematic Analysis of Transverse Sinus Stenting.

Mohamed S Teleb, Matthew E Cziep, Marc A Lazzaro, Ayman Gheith, Kaiz Asif, Bernd Remler, Osama O Zaidat,

Idiopathic intracranial hypertension (IIH) is a disorder characterized by signs and symptoms of increased intracranial pressure without structural cause seen on conventional imaging. Hallmark treatment after failed medical management, has been CSF shunting or optic nerve fenestration with the goal of treatment being preservation of vision. Recently, there have been ... Read more >>

Interv Neurol (Interventional neurology)
[2013, 2(3):132-143]

Cited: 17 times

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The diagnosis and management of brain arteriovenous malformations.

Roberta L Novakovic, Marc A Lazzaro, Alicia C Castonguay, Osama O Zaidat,

Although uncommon in the general population, cerebral arteriovenous malformations (AVMs) can pose a significant health risk if a rupture occurs. Advances in noninvasive imaging have led to an increase in the identification of unruptured AVMs, presenting new challenges in management, given their poorly understood natural history. Over the past decade, ... Read more >>

Neurol Clin (Neurologic clinics)
[2013, 31(3):749-763]

Cited: 13 times

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The natural history of vertebral artery origin stenosis.

Matthew C Thompson, Mohammad A Issa, Marc A Lazzaro, Osama O Zaidat,

BACKGROUND: We sought to determine the long-term survival and natural history of vertebral artery origin stenosis (VAOS) as it relates to stroke. METHODS: We retrospectively reviewed clinical data on patients admitted at a single institution for possible stroke between 2004 and 2007 and selected subjects who underwent angiography of the ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2014, 23(1):e1-4]

Cited: 2 times

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The effect of time of day on cold water ingestion by high-level swimmers in a tropical climate.

Olivier Hue, Roland Monjo, Marc Lazzaro, Michelle Baillot, Philippe Hellard, Laurent Marlin, A Jean-Etienne,

The authors tested the effect of cold water ingestion during high-intensity training in the morning vs the evening on both core temperature (TC) and thermal perceptions of internationally ranked long-distance swimmers during a training period in a tropical climate. Nine internationally ranked long-distance swimmers (5 men and 4 women) performed ... Read more >>

Int J Sports Physiol Perform (International journal of sports physiology and performance)
[2013, 8(4):442-451]

Cited: 5 times

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Venous sinus pulsatility and the potential role of dural incompetence in idiopathic intracranial hypertension.

Marc A Lazzaro, Ziad Darkhabani, Bernd F Remler, Sang H Hong, Thomas J Wolfe, Osama O Zaidat, Brian-Fred Fitzsimmons,

BACKGROUND: Idiopathic intracranial hypertension (IIH) remains a poorly understood and therapeutically challenging disease. Enthusiasm has emerged for endovascular therapy with stent reconstruction of dural sinus narrowing; however, a complete understanding of the hydrodynamic dysequilibrium is lacking. OBJECTIVE: To review and characterize catheter manometry findings including pulsatility changes within the venous ... Read more >>

Neurosurgery (Neurosurgery)
[2012, 71(4):877-883]

Cited: 8 times

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Developing practice recommendations for endovascular revascularization for acute ischemic stroke.

Marc A Lazzaro, Roberta L Novakovic, Andrei V Alexandrov, Ziad Darkhabani, Randall C Edgell, Joey English, Donald Frei, Dara G Jamieson, Vallabh Janardhan, Nazli Janjua, Rashid M Janjua, Irene Katzan, Pooja Khatri, Jawad F Kirmani, David S Liebeskind, Italo Linfante, Thanh N Nguyen, Jeffrey L Saver, Lori Shutter, Andrew Xavier, Dileep Yavagal, Osama O Zaidat,

Guidelines have been established for the management of acute ischemic stroke; however, specific recommendations for endovascular revascularization therapy are lacking. Burgeoning investigation of endovascular revascularization therapies for acute ischemic stroke, rapid device development, and a diverse training background of the providers performing the procedures underscore the need for practice recommendations. ... Read more >>

Neurology (Neurology)
[2012, 79(13 Suppl 1):S243-55]

Cited: 11 times

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Demand-supply of neurointerventionalists for endovascular ischemic stroke therapy.

Osama O Zaidat, Marc Lazzaro, Emily McGinley, Randall C Edgell, Thanh Nguyen, Italo Linfante, Nazli Janjua,

OBJECTIVE: To estimate the needed workforce of trained neurointerventionalists (NIs) to perform endovascular therapy (ET) for eligible patients with acute ischemic stroke (AIS). METHOD: Population and ischemic stroke incidence data were extracted with use of US Census and Centers for Disease Control and Prevention 2009 estimates. The annual "demand" is ... Read more >>

Neurology (Neurology)
[2012, 79(13 Suppl 1):S35-41]

Cited: 25 times

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Vascular neurologists and neurointerventionalists on endovascular stroke care: polling results.

Thanh N Nguyen, Osama O Zaidat, Randall C Edgell, Nazli Janjua, Dileep R Yavagal, Andrew R Xavier, Jawad F Kirmani, David S Liebeskind, Raul G Nogueira, Nirav A Vora, John R Sims, John R Lynch, Brian-Fred Fitzsimmons, Thomas J Wolfe, Michael Chen, Aamir Badruddin, Darin B Zahuranec, David L McDonagh, Vallabh Janardhan, Birgul Bastan, Jane A Madden, Nerses Sanossian, Rishi Gupta, Marc A Lazzaro, Tudor G Jovin, Alex Abou-Chebl, Italo Linfante, Syed I Hussain,

Neurology (Neurology)
[2012, 79(13 Suppl 1):S5-15]

Cited: 2 times

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Complications of endovascular therapy for acute ischemic stroke and proposed management approach.

Ziad Darkhabani, Thanh Nguyen, Marc A Lazzaro, Osama O Zaidat, John R Lynch, Brian-Fred Fitzsimmons, Italo Linfante,

Over the past decade, endovascular therapy has emerged as a promising therapeutic approach for select patients with acute ischemic stroke. However, the morbidity, mortality, and complication rates in intra-arterial recanalization trials are higher than in the National Institute of Neurological Disorders and Stroke trial of IV tissue plasminogen activator. This ... Read more >>

Neurology (Neurology)
[2012, 79(13 Suppl 1):S192-8]

Cited: 9 times

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Interventional Management of Stroke III trial: establishing the foundation.

Osama O Zaidat, Marc A Lazzaro, Rishi Gupta, Dileep R Yavagal, Peter A Rasmussen, Joshua A Hirsch, Alicia C Castonguay, Robert W Tarr,

J Neurointerv Surg (Journal of neurointerventional surgery)
[2012, 4(4):235-237]

Cited: 5 times

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Surveillance imaging after intracranial stent implantation: non-invasive imaging compared with digital subtraction angiography.

Behrad Golshani, Marc A Lazzaro, Flavius Raslau, Ziad Darkhabani, Dhiraj Baruah, Daniel Eastwood, Brian-Fred Fitzsimmons, Osama O Zaidat,

BACKGROUND: Digital subtraction angiography (DSA) is the gold standard imaging for detection of in-stent restenosis (ISR) but there is limited literature on optimal non-invasive surveillance imaging. In this study, the ability of CT angiography (CTA) and MR angiography (MRA) compared with DSA in recognizing ISR was assessed. METHODS: A single ... Read more >>

J Neurointerv Surg (Journal of neurointerventional surgery)
[2013, 5(4):361-365]

Cited: 4 times

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