Full Text Journal Articles by
Author Marc C Smaldone

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Renal mass biopsy: A strategy to reduce associated costs and morbidity when managing localized renal masses.

Abhishek Srivastava, Robert N Uzzo, Jennifer Lee, Eric Cho, Alex Grieco, Selma Masic, Elizabeth Handorf, David Y T Chen, Rosalia Viterbo, Richard E Greenberg, Marc C Smaldone, Alexander Kutikov, Robert G Uzzo,

<h4>Introduction and objectives</h4>Renal mass biopsy (RMB) has not been widely adopted in evaluating small renal mass due to concerns for safety, efficacy, and its perceived lack of consequence on management decisions. We assess the potential cost savings and morbidity avoidance of routine RMB on cT1 renal masses undergoing robotic-assisted partial ... Read more >>

Urol Oncol (Urologic oncology)
[2021, :]

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Identification of oncological characteristics associated with improved overall survival in patients with adrenocortical carcinoma treated with adjuvant radiation therapy: Insights from the National Cancer Database.

Kevin B Ginsburg, Akhil A Chandra, Jared P Schober, Elizabeth A Handorf, Robert G Uzzo, Richard E Greenberg, David Yt Chen, Rosalia Viterbo, Marc C Smaldone, Alexander Kutikov, Mark A Hallman, Andres F Correa,

<h4>Objectives</h4>To test for an association between oncological risk factors and overall survival in patients with non-metastatic adrenocortical carcinoma treated with adjuvant radiation therapy at high-risk for recurrence per NCCN guidelines.<h4>Materials and methods</h4>We analyzed data from patients undergoing surgical resection with or without aRT in the NCDB from 2004 to 2017. ... Read more >>

Urol Oncol (Urologic oncology)
[2021, :]

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Assessment of Prostate Cancer Treatment Among Black and White Patients During the COVID-19 Pandemic.

Adrien N Bernstein, Ruchika Talwar, Elizabeth Handorf, Kaynaat Syed, John Danella, Serge Ginzburg, Laurence Belkoff, Adam C Reese, Jeffery Tomaszewski, Edouard Trabulsi, Eric A Singer, Bruce Jacobs, Alexander Kutikov, Robert Uzzo, Jay D Raman, Thomas Guzzo, Marc C Smaldone, Andres Correa,

<h4>Importance</h4>Early in the COVID-19 pandemic, racial/ethnic minority communities disproportionately experienced poor outcomes; however, the association of the pandemic with prostate cancer (PCa) care is unknown.<h4>Objective</h4>To assess the association between race and PCa care delivery for Black and White patients during the first wave of the COVID-19 pandemic.<h4>Design, setting, and participants</h4>This ... Read more >>

JAMA Oncol (JAMA oncology)
[2021, :]

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Robotic renal surgery for renal cell carcinoma with inferior vena cava thrombus.

Selma Masic, Marc C Smaldone,

Surgical management of renal cell carcinoma (RCC) with inferior vena cava (IVC) thrombus is inherently complex, posing challenges for even the most experienced urologists. Until the mid-2000s, nephrectomy with IVC thrombectomy was exclusively performed using variations of the open technique initially described decades earlier, but since then several institutions have ... Read more >>

Transl Androl Urol (Translational andrology and urology)
[2021, 10(5):2195-2198]

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Current controversies in minimally invasive urologic oncology.

Marc C Smaldone, Jeffrey J Tomaszewski,

Transl Androl Urol (Translational andrology and urology)
[2021, 10(5):2149-2150]

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Research highlights of the 2020 society of urologic oncology young urologic oncologists' program.

Zachary Klaassen, Kristen R Scarpato, Benjamin T Ristau, Kelly L Stratton, Sima P Porten, Marc C Smaldone, Brian F Chapin, Sarah P Psutka,

Urol Oncol (Urologic oncology)
[2021, :]

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Safety of neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer and malignant ureteric obstruction.

Marshall C Strother, Alexander Kutikov, Matthew Epstein, Emily Bochner, Mengying Deng, Elizabeth Handorf, Bianca Lewis, Pooja Ghatalia, Richard E Greenberg, David Chen, Rosalia Viterbo, Fern Anari, Marc C Smaldone, Matthew R Zibelman, Robert G Uzzo, Elizabeth R Plimack, Daniel M Geynisman,

<h4>Objectives</h4>To determine whether patients with carcinoma invading bladder muscle (MIBC) and ureteric obstruction can safely receive cisplatin-based neoadjuvant chemotherapy (C-NAC), and to determine whether such patients require relief of obstruction with a ureteric stent or percutaneous nephrostomy prior to beginning C-NAC.<h4>Patients and methods</h4>We performed a single-institution retrospective analysis of MIBC ... Read more >>

BJU Int (BJU international)
[2021, :]

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Cystoscopy and Systematic Bladder Tissue Sampling in Predicting pT0 Bladder Cancer: A Prospective Trial.

Matthew Zibelman, Aeen M Asghar, Daniel C Parker, John O'Neill, Shuanzeng Wei, Richard E Greenberg, Marc C Smaldone, David Y T Chen, Rosalia Viterbo, Robert G Uzzo, Evan Bloom, Rutika Kokate, Daniel M Geynisman, Pooja Ghatalia, Mengying Deng, Eric A Ross, Elizabeth Plimack, Philip H Abbosh, Alexander Kutikov,

<h4>Purpose</h4>Concern for discordance between clinical staging and final pathology drives current management of patients deemed appropriate candidates for radical cystectomy. Therefore, we set out to prospectively investigate reliability and shortcomings of cystoscopic evaluation in radical cystectomy candidates.<h4>Materials and methods</h4>Patients undergoing radical cystectomy for urothelial carcinoma were enrolled in a prospective ... Read more >>

J Urol (The Journal of urology)
[2021, 205(6):1605-1611]

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Reply by Authors.

Daniel M Geynisman, Brian T Kadow, Brian M Shuch, Stephen A Boorjian, Surena F Matin, Edward Rampersaud, Barton N Milestone, Elizabeth R Plimack, Matthew R Zibelman, Alexander Kutikov, Marc C Smaldone, David Yt Chen, Rosalia Viterbo, Shreyas Joshi, Richard E Greenberg, Lois Malizzia, Thomas McGowan, Eric A Ross, Robert G Uzzo,

J Urol (The Journal of urology)
[2020, 204(3):536-537]

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Sporadic Angiomyolipomas Growth Kinetics While on Everolimus: Results of a Phase II Trial.

Daniel M Geynisman, Brian T Kadow, Brian M Shuch, Stephen A Boorjian, Surena F Matin, Edward Rampersaud, Barton N Milestone, Elizabeth R Plimack, Matthew R Zibelman, Alexander Kutikov, Marc C Smaldone, David Yt Chen, Rosalia Viterbo, Shreyas Joshi, Richard E Greenberg, Lois Malizzia, Thomas McGowan, Eric A Ross, Robert G Uzzo,

PURPOSE:Everolimus decreases tumor volume of renal angiomyolipomas in patients with tuberous sclerosis. No prospective data are available regarding the effect of everolimus on the growth kinetics in patients with sporadic angiomyolipomas. We sought to determine the safety and efficacy of everolimus in the volumetric reduction of sporadic angiomyolipomas. MATERIALS AND ... Read more >>

J Urol (The Journal of urology)
[2020, 204(3):531-537]

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Reply by Authors.

Andrea Minervini, Riccardo Campi, Brian R Lane, Ottavio De Cobelli, Francesco Sanguedolce, Georgios Hatzichristodoulou, Alessandro Antonelli, Sabrina Noyes, Andrea Mari, Oscar Rodriguez-Faba, Frank X Keeley, Johan Langenhuijsen, Gennaro Musi, Tobias Klatte, Marco Roscigno, Bulent Akdogan, Maria Furlan, Nihat Karakoyunlu, Martin Marszalek, Umberto Capitanio, Alessandro Volpe, Sabine Brookman-May, Jürgen E Gschwend, Marc C Smaldone, Robert G Uzzo, Marco Carini, Alexander Kutikov,

J Urol (The Journal of urology)
[2020, 203(3):503-504]

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The volume-outcome relationship in kidney cancer: is more really better?

Brian T Kadow, Shreyas S Joshi, Alexander Kutikov, Elizabeth Handorf, Marc C Smaldone, Robert G Uzzo, Daniel M Geynisman,

Ann Transl Med (Annals of translational medicine)
[2019, 7(Suppl 8):S336]

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Impact of Resection Technique on Perioperative Outcomes and Surgical Margins after Partial Nephrectomy for Localized Renal Masses: A Prospective Multicenter Study.

Andrea Minervini, Riccardo Campi, Brian R Lane, Ottavio De Cobelli, Francesco Sanguedolce, Georgios Hatzichristodoulou, Alessandro Antonelli, Sabrina Noyes, Andrea Mari, Oscar Rodriguez-Faba, Frank X Keeley, Johan Langenhuijsen, Gennaro Musi, Tobias Klatte, Marco Roscigno, Bulent Akdogan, Maria Furlan, Nihat Karakoyunlu, Martin Marszalek, Umberto Capitanio, Alessandro Volpe, Sabine Brookman-May, Jürgen E Gschwend, Marc C Smaldone, Robert G Uzzo, Marco Carini, Alexander Kutikov,

<h4>Purpose</h4>The impact of resection technique on partial nephrectomy outcomes is controversial. The aim of this study was to evaluate the pattern of resection techniques during partial nephrectomy and the impact on perioperative outcomes, acute kidney injury, positive surgical margins and the achievement of the Trifecta (negative surgical margins, no perioperative ... Read more >>

J Urol (The Journal of urology)
[2020, 203(3):496-504]

Cited: 8 times

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Pathologic measures of quality compare favorably in patients undergoing robot-assisted radical cystectomy to open cystectomy cohorts: a National Cancer Database analysis.

Carla M Miguel, Kaitlin E Kosinski, Melissa J Fazzari, Michael Kongnyuy, Marc C Smaldone, Jeffrey T Schiff, Aaron E Katz, Anthony T Corcoran,

This study aims to assess the impact of facility characteristics on measures of surgical quality (positive surgical margin rates and lymph-node yield) in patients undergoing robot-assisted (RARC) versus open (ORC) radical cystectomy using the National Cancer Database. Patients who received RC between the years of 2010-2013 were stratified according to ... Read more >>

J Robot Surg (Journal of robotic surgery)
[2020, 14(4):609-614]

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Safety and delayed intervention rates of active surveillance for small renal masses in an elderly population.

Brian T Kadow, Marc C Smaldone,

Ann Transl Med (Annals of translational medicine)
[2019, 7(Suppl 6):S182]

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Trends in Regionalization of Care and Mortality For Patients Treated With Radical Cystectomy.

Nikhil Waingankar, Katherine Mallin, Brian L Egleston, David P Winchester, Robert G Uzzo, Alexander Kutikov, Marc C Smaldone,

<h4>Background</h4>Regionalization to higher volume centers has been proposed as a mechanism to improve short-term outcomes following complex surgery.<h4>Objective</h4>The objective of this study was to assess trends in regionalization and mortality for patients undergoing radical cystectomy (RC).<h4>Research design</h4>An observational study of patients receiving RC in the United States from 2004 to ... Read more >>

Med Care (Medical care)
[2019, 57(9):728-733]

Cited: 2 times

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Non-contrast imaging characteristics of papillary renal cell carcinoma: implications for diagnosis and subtyping.

Anand V Badri, Nikhil Waingankar, Kristin Edwards, Alexander Kutikov, Rosaleen B Parsons, David Y Chen, Marc C Smaldone, Rosalia Viterbo, Richard E Greenberg, Robert G Uzzo,

INTRODUCTION:Current radiographic guidelines suggest unenhanced renal lesions < 20 Hounsfield Units (HU) are overwhelmingly benign, requiring no further evaluation. We evaluate our experience with papillary renal cell carcinoma (pRCC) presenting with low pre-contrast attenuation and the relationship of attenuation with histologic pRCC subtype. MATERIALS AND METHODS:We reviewed our institutional kidney ... Read more >>

Can J Urol (The Canadian journal of urology)
[2019, 26(5):9916-9921]

Cited: 1 time

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Treatment Facility Volume and Survival in Patients with Advanced Prostate Cancer.

Shreyas S Joshi, Elizabeth R Handorf, Danielle Sienko, Matthew Zibelman, Robert G Uzzo, Alexander Kutikov, Eric M Horwitz, Marc C Smaldone, Daniel M Geynisman,

<h4>Background</h4>Despite improvements in medical management of advanced prostate cancer (aPC), it continues to be a leading cause of cancer death in men. Contemporary management of men with aPC is complex and requires resources to be more readily available at high-volume facilities.<h4>Objective</h4>To determine the relationship between facility volume and survival in ... Read more >>

Eur Urol Oncol (European urology oncology)
[2020, 3(1):104-111]

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Prediction of significant estimated glomerular filtration rate decline after renal unit removal to aid in the clinical choice between radical and partial nephrectomy in patients with a renal mass and normal renal function.

Andrew G McIntosh, Daniel C Parker, Brian L Egleston, Robert G Uzzo, Mohammed Haseebuddin, Shreyas S Joshi, Rosalia Viterbo, Richard E Greenberg, David Y T Chen, Marc C Smaldone, Alexander Kutikov,

<h4>Objectives</h4>To develop a clinically applicable predictive model to quantitate the risk of estimated glomerular filtration rate (eGFR) decline to ≤45 mL/min/1.73 m<sup>2</sup> after radical nephrectomy (RN) to better inform decisions between RN and partial nephrectomy (PN).<h4>Patients and methods</h4>Our prospectively maintained kidney cancer registry was reviewed for patients with a preoperative eGFR >60 mL/min/1.73 m<sup>2</sup> ... Read more >>

BJU Int (BJU international)
[2019, 124(6):999-1005]

Cited: 4 times

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Treatment delays for muscle-invasive bladder cancer.

Selma Masic, Marc C Smaldone,

Cancer (Cancer)
[2019, 125(12):1973-1975]

Cited: 1 time

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Incisional hernia after cystectomy: incidence, risk factors and anthropometric predisposition.

Daniel C Edwards, David B Cahn, Madhu Reddy, Dana Kivlin, Aseem Malhotra, Tianyu Li, David Y T Chen, Rosalia Viterbo, Robert G Uzzo, Richard E Greenberg, Marc C Smaldone, Paul Curcillo, Alexander Kutikov,

INTRODUCTION:Postoperative incisional hernias (PIH) are an established complication of abdominal surgery with rates after radical cystectomy (RC) poorly defined. The objective of this analysis is to compare rates and risk factors of PIH after open (ORC) and robotic-assisted (RARC) cystectomy at a tertiary-care referral center. MATERIALS AND METHODS:We performed a ... Read more >>

Can J Urol (The Canadian journal of urology)
[2018, 25(6):9573-9578]

Cited: 1 time

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Performance Measurement and Quality Improvement Initiatives for Bladder Cancer Care.

Benjamin T Ristau, Marc C Smaldone,

<h4>Purpose of review</h4>Bladder cancer care is costly due to long surveillance periods for non-muscle-invasive bladder cancer (NMIBC) and comorbidities associated with the surgical treatment of muscle-invasive bladder cancer (MIBC). We reviewed current evidence-based practices and propose quality metrics for NMIBC and MIBC.<h4>Recent findings</h4>For patients with NMIBC, we propose four categories ... Read more >>

Curr Urol Rep (Current urology reports)
[2018, 19(12):100]

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Renal Hilar Lesions: Biological Implications for Complex Partial Nephrectomy.

Andres F Correa, Hilary Yankey, Tianyu Li, Shreyas S Joshi, Alexander Kutikov, David Y Chen, Rosalia Viterbo, Richard E Greenberg, Marc C Smaldone, Robert G Uzzo,

<h4>Objective</h4>To perform a comprehensive histopathologic review of sporadic resected solitary cT1 renal masses comparing those with and without radiographic involvement of the hilum.<h4>Materials and methods</h4>A prospectively maintained database was queried for all cT1 renal masses undergoing resection classified per the R.E.N.A.L. nephrometry score. Hilar masses were defined as tumors that ... Read more >>

Urology (Urology)
[2019, 123:174-180]

Cited: 3 times

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Perceptions of Prostate MRI and Fusion Biopsy of Radiation Oncologists and Urologists for Patients Diagnosed with Prostate Cancer: Results from a National Survey.

Laura Bukavina, Jon C Tilburt, Badrinath Konety, Nilay D Shah, Cary P Gross, James B Yu, Frederick Schumacher, Alexander Kutikov, Marc C Smaldone, Simon P Kim,

<h4>Background</h4>Magnetic resonance imaging (MRI) of the prostate and fusion biopsy have been advanced to improve the detection of clinically significant prostate cancer (PCa). Yet, frequency of their use and contemporary attitudes among radiation oncologists (ROs) and urologists (UROs) remain largely unknown.<h4>Objective</h4>We performed a national survey of UROs and ROs to ... Read more >>

Eur Urol Focus (European urology focus)
[2020, 6(2):273-279]

Cited: 3 times

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Bladder Extirpation vs Preservation: The Treatment Debate.

David B Cahn, Elizabeth A Handorf, Marc C Smaldone,

JAMA Surg (JAMA surgery)
[2018, 153(10):889-890]

Cited: 1 time

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