Full Text Journal Articles by
Author Manphool Singhal

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Deficiency of adenosine deaminase 2 (DADA2) in Adults and Children: Experience from India.

Aman Sharma, Gsrsnk Naidu, Vikas Sharma, Saket Jha, Aaadhar Dhooria, Varun Dhir, Prateek Bhatia, Vishal Sharma, Sagar Bhattad, Chengappa, Vikas Gupta, Durga Prasanna Misra, Pallavi Pimpale Chavan, Sourabh Malaviya, Rajkiran Dudam, Banwari Sharma, Sathish Kumar, Rajesh Bhojwani, Pankaj Gupta, Vikas Agarwal, Kusum Sharma, Manphool Singhal, Manish Rathi, Ritambhra Nada, Ranjana W Minz, Ved Chaturvedi, Amita Aggarwal, Rohini Handa, Alice Grossi, Marco Gattorno, Zhengping Huang, Jun Wang, Ramesh Jois, V S Negi, Raju Khubchandani, Sanjay Jain, Juan I Arostegui, Eugene P Chambers, Michael S Hershfield, Ivona Aksentijevich, Qing Zhou, Pui Y Lee,

OBJECTIVE:Deficiency of adenosine deaminase 2 (DADA2) is a potentially fatal monogenic syndrome characterized by variable manifestations of systemic vasculitis, bone marrow failure and immunodeficiency. Most cases are diagnosed by paediatric care providers given the typical early age of disease onset. We aim to describe the clinical phenotypes and treatment response ... Read more >>

(Arthritis & rheumatology (Hoboken, N.J.))
[2020, :]

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Role of DECT in coronary artery disease: a comparative study with ICA and SPECT.

Kamireddy V Prasad Reddy, Manphool Singhal, Rajesh Vijayvergiya, Ashwani Sood, Niranjan Khandelwal,

PURPOSE:Earlier imaging techniques for coronary artery disease (CAD) focused primarily on either morphological or functional assessment of CAD. However, dual-energy computed tomography (DECT) can be used to assess myocardial blood supply both morphologically and functionally. We aimed to evaluate the diagnostic accuracy of DECT in detecting morphological and functional components ... Read more >>

Diagn Interv Radiol (Diagnostic and interventional radiology (Ankara, Turkey))
[2020, 26(5):420-428]

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Extensive Oral Scarring and Bilateral Subclavian Artery Stenosis in Pediatric-Onset Behçet's Disease.

Pandiarajan Vignesh, Manphool Singhal, Deepti Suri, Nandita Kakkar, Ebun Omoyinmi, Paul Brogan, Surjit Singh,

J Clin Rheumatol (Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases)
[2020, 26(5):e91-e92]

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Calcified Saccular Coronary Artery Aneurysm of Kawasaki Disease.

Manphool Singhal, Pandiarajan Vignesh, N Khandelwal, Surjit Singh,

J Clin Rheumatol (Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases)
[2020, 26(5):e96]

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Kawasaki Disease Presenting as Fever and Urinary Tract Infection.

Rakesh Kumar Pilania, Purbasha Misra, Sandesh Guleria, Manphool Singhal, Anju Gupta, Surjit Singh,

J Clin Rheumatol (Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases)
[2020, 26(5):e97-e98]

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Silent Myocarditis in Takayasu Arteritis.

Arghya Chattopadhyay, Manphool Singhal, Uma Debi, Aman Sharma, Sanjay Jain,

J Clin Rheumatol (Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases)
[2020, 26(5):e99]

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A high frequency of Gilbert syndrome (UGT1A1*28/*28) and associated hyperbilirubinemia but not cholelithiasis in adolescent and adult north Indian patients with transfusion-dependent β-thalassemia.

Oshan Shrestha, Alka Rani Khadwal, Manphool Singhal, Amita Trehan, Deepak Bansal, Richa Jain, Arnab Pal, Jasbir Kaur Hira, Sanjeev Chhabra, Pankaj Malhotra, Reena Das, Prashant Sharma,

Hyperbilirubinemia and pigment gallstones are frequent complications in transfusion-dependent β-thalassemia (TDβT) patients. Bilirubin production and clearance are determined by genetic as well as environmental variables like ineffective erythropoiesis, hemolysis, infection-induced hepatic injury, and drug- or iron-related toxicities. We studied the frequency of the Gilbert syndrome (GS), a common hereditary cause ... Read more >>

Ann. Hematol. (Annals of hematology)
[2020, 99(9):2019-2026]

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Hypotension in a Febrile Child-Beware of Kawasaki Disease Shock Syndrome.

Rakesh Kumar Pilania, Ankur Kumar Jindal, Vaddi Vamsi Srikrishna, Madhusudan Samprathi, Manphool Singhal, Surjit Singh,

J Clin Rheumatol (Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases)
[2020, 26(5):e130-e131]

Cited: 1 time

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18F-NaF PET uptake characteristics of coronary artery culprit lesions in a cohort of patients of acute coronary syndrome with ST-elevation myocardial infarction and chronic stable angina: A hybrid fluoride PET/CTCA study.

Abhiram G Ashwathanarayana, Manphool Singhal, Swayamjeet Satapathy, Ashwani Sood, Bhagwant Rai Mittal, Rohit Manoj Kumar, Madan Parmar, Darshan Krishnappa, Nivedita Rana,

BACKGROUND:18F-NaF PET/CT identifies high-risk plaques due to active calcification in coronary arteries with potential to characterize plaques in ST-elevation myocardial infarction (MI) and chronic stable angina (CSA) patients. METHODS:Twenty-four MI and 17 CSA patients were evaluated with 18F-NaF PET/CTCA for SUVmax and TBR values of culprit and non-culprit plaques in ... Read more >>

J Nucl Cardiol (Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology)
[2020, :]

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CT Coronary Angiography Studies After a Mean Follow-up of 3.8 Years in Children With Kawasaki Disease and Spontaneous Defervescence.

Santosh Dusad, Manphool Singhal, Rakesh Kumar Pilania, Deepti Suri, Surjit Singh,

Background: There is paucity of literature on follow-up of children with Kawasaki disease (KD) who have spontaneous defervescence during the acute stage and do not receive intravenous immunoglobulin. We report herein the role of computed tomography coronary angiography (CTCA) as an imaging modality in such situations. Methods: This prospective observational ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:274]

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Non-bronchial causes of haemoptysis: imaging and interventions.

Manphool Singhal, Anupam Lal, Nidhi Prabhakar, Mukesh K Yadav, Rajesh Vijayvergiya, Digamber Behra, Niranjan Khandelwal,

Purpose:To describe non-bronchial causes of haemoptysis on imaging and the role of interventional radiology in their management from cases of haemoptysis archived from our database at a tertiary care, federally funded institution. Material and methods:Retrospective analysis of cases that presented with haemoptysis in our institution from 2008 to 2013 was ... Read more >>

Pol J Radiol (Polish journal of radiology)
[2020, 85:e328-e339]

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Unilateral Limb Atrophy: Is it a Forme Fruste Localized Scleroderma?

Dharmagat Bhattarai, Pandiarajan Vignesh, Sandesh Guleria, Anindita Sinha, Manphool Singhal,

Indian Dermatol Online J (Indian dermatology online journal)
[2020, 11(3):451-452]

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Kawasaki Disease in Children Older Than 10 Years: A Clinical Experience From Northwest India.

Ankur Kumar Jindal, Rakesh Kumar Pilania, Sandesh Guleria, Pandiarajan Vignesh, Deepti Suri, Anju Gupta, Manphool Singhal, Amit Rawat, Surjit Singh,

Background: Kawasaki disease (KD) is predominantly seen in young children (<5 years). Diagnosis of KD is often delayed in older children and adolescents, leading to a higher risk of coronary artery abnormalities (CAAs). There is a paucity of literature on KD in older children. Methods: Data were collated from a ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:24]

Cited: 1 time

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Assessment of Endothelial Dysfunction in Acute and Convalescent Phases of Kawasaki Disease Using Automated Edge Detection Software: A Preliminary Study From North India.

Santhosh Kumar Routhu, Manphool Singhal, Ankur Kumar Jindal, Vivek Kumar, Ashok Kumar Yadav, Surjit Singh,

OBJECTIVE:The aim of this study was to assess endothelial dysfunction in acute and convalescent phases of Kawasaki disease (KD) using automated edge detection software. METHODS:This was a case-control study to assess the flow-mediated dilatation (FMD) of brachial artery (BA) in patients with KD during acute phase and at least 3 ... Read more >>

J Clin Rheumatol (Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases)
[2019, :]

Cited: 1 time

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Comparison between computerized tomography-guided bronchial width measurement versus conventional method for selection of adequate double lumen tube size.

Praneeth Suvvari, Bhupesh Kumar, Manphool Singhal, Harkant Singh,

Background:Selection of adequate size double lumen tube (DLT) is complicated by marked inter-individual variability in morphology and dimensions of tracheobronchial tree. Computerized tomography (CT)-guided left bronchus width measurement has been used to predict adequate size DLT in European and Singapore population; however, no such data exist for Indian population who ... Read more >>

Ann Card Anaesth (Annals of cardiac anaesthesia)
[2019, 22(4):358-364]

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Percutaneous glue embolization as a primary treatment for visceral pseudoaneurysms.

Ujjwal Gorsi, Shreedhara Chaluvashetty, Naveen Kalra, Mandeep Kang, Vikas Bhatia, Anupam Lal, Manphool Singhal, Sameer Vyas, Chirag Kamal Ahuja, Ajay Kumar, Vivek Gupta, Niranjan Khandelwal,

Aim: To evaluate the feasibility and outcome of percutaneous glue embolisation as primary treatment for pseudoaneurysms in selective patients.Material and methods: A review of the pseudoaneurysm cases managed with percutaneous glue at our institute was analyzed in this study. A total of 21 patients over a period of last one ... Read more >>

Minim Invasive Ther Allied Technol (Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy)
[2020, 29(3):170-176]

Cited: 2 times

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Encapsulating Peritoneal Sclerosis: The Abdominal Cocoon.

Manphool Singhal, Satheesh Krishna, Anupam Lal, Sabarish Narayanasamy, Amanjit Bal, Thakur D Yadav, Rakesh Kochhar, Saroj K Sinha, Niranjan Khandelwal, Adnan M Sheikh,

Encapsulating peritoneal sclerosis (EPS) is a rare but serious condition that results in (a) encapsulation of bowel within a thickened fibrocollagenous peritoneal membrane and (b) recurrent episodes of bowel obstruction. Although described by various names in the literature, the preferred term is encapsulating peritoneal sclerosis because it best describes the ... Read more >>

Radiographics (Radiographics : a review publication of the Radiological Society of North America, Inc)
[2019, 39(1):62-77]

Cited: 1 time

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Imaging in small and medium vessel vasculitis.

Manphool Singhal, Pankaj Gupta, Aman Sharma,

Vasculitis includes a group of disorders characterized by inflammation of the vessel wall and classified based on the diameter of the predominantly involved vessels. Granulomatosis with polyangiitis, microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis and Henoch-Schonlein purpura are the important entities in the small vessel vasculitis group, while polyarteritis nodosa and ... Read more >>

Int J Rheum Dis (International journal of rheumatic diseases)
[2019, 22 Suppl 1:78-85]

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Complex interventions of abdominal aorta and its branches in children with Takayasu arteritis: Clinical experience from a tertiary care center in north-west India.

Rajesh Vijayvergiya, Ankur K Jindal, Rakesh K Pilania, Deepti Suri, Anju Gupta, Ashish Sharma, Saroj K Sinha, Manphool Singhal, Ajay Bahl, Surjit Singh,

AIM:To report our experience on complex percutaneous interventions of the abdominal aorta and its branches in six children with Takayasu arteritis (TA). METHODS:A review of records of children with TA, who underwent percutaneous interventions of the abdominal aorta and its major branches. RESULTS:In this analysis, we included six children with ... Read more >>

Int J Rheum Dis (International journal of rheumatic diseases)
[2019, 22(1):140-151]

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Unusual Presentation of Hurthle Cell Carcinoma With TENIS Syndrome as Left Atrial Thrombus on 18F-FDG PET/CT.

Apurva Sood, Ashwin Singh Parihar, Ashwani Sood, Rajender Kumar, Gaurav Prakash, Manphool Singhal, Ajay Gulati, Bhagwant Rai Mittal, Ajay Bahl, Shashank Singh,

Differentiated thyroid cancer (DTC) with thyroglobulin elevation and negative I scintigraphy (TENIS) syndrome is a diagnostic and therapeutic dilemma. Treatment of differentiated thyroid cancer has an excellent outcome, but treatment options in TENIS are limited with the exception of surgically amenable disease. We present a case of TENIS syndrome with ... Read more >>

Clin Nucl Med (Clinical nuclear medicine)
[2018, 43(10):e352-e354]

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Endovascular management of internal carotid artery pseudoaneurysms: A single-centre experience of 20 patients.

Ajay Kumar, Anuj Prabhakar, Vivek Gupta, Niranjan Khandelwal, Chirag K Ahuja, Manphool Singhal, Sameer Vyas, Naresh K Panda, Pankaj C Vaidhya,

Background:Pseudoaneurysms (PSAs) of the internal carotid artery (ICA) are uncommon lesions. Various surgical and endovascular options are available for the management of these lesions. We describe our experience in using a spectrum of endovascular management strategies for ICA-PSA and present their outcome. Aims:To evaluate the role and efficacy of endovascular ... Read more >>

Neurol India (Neurology India)
[2018, 66(4):1067-1074]

Cited: 1 time

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Macrocephaly, epilepsy and intracranial cysts: an image to remember.

Mounika Endrakanti, Vijay Gonda, Arushi Gahlot Saini, Manphool Singhal,

BMJ Case Rep (BMJ case reports)
[2018, 2018:]

Cited: 0 times

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Moyamoya Syndrome in a Child With HIV-1 Infection.

Ankur Kumar Jindal, Sagar Bhattad, Deepti Suri, Manphool Singhal, Aman Gupta, Paramjeet Singh,

Neurologic manifestations of HIV infection are not uncommon. However, stroke secondary to Moyamoya syndrome has rarely been described in children with HIV infection. We report a 10-year-old boy with perinatally acquired HIV-1 infection, who presented with recurrent strokes while on antiretroviral therapy. ... Read more >>

Pediatr. Infect. Dis. J. (The Pediatric infectious disease journal)
[2018, 37(6):e166-e167]

Cited: 0 times

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Cross-sectional Imaging of Gallbladder Carcinoma: An Update.

Naveen Kalra, Pankaj Gupta, Manphool Singhal, Rajesh Gupta, Vikas Gupta, Radhika Srinivasan, Bhagwant R Mittal, Radha K Dhiman, Niranjan Khandelwal,

Gallbladder Carcinoma (GBCA) is the most common biliary tract malignancy. As the disease is often diagnosed clinically in an advanced stage, the survival rates are dismal. Imaging studies allow for an early diagnosis of malignancy, though the findings may be indistinguishable from non-malignant disease processes affecting the gallbladder. Attempts have ... Read more >>

J Clin Exp Hepatol (Journal of clinical and experimental hepatology)
[2019, 9(3):334-344]

Cited: 0 times

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Vascular function and cholecalciferol supplementation in CKD: A self-controlled case series.

Vivek Kumar, Ashok Kumar Yadav, Manphool Singhal, Vinod Kumar, Anupam Lal, Debasish Banerjee, Krishan Lal Gupta, Vivekanand Jha,

Vitamin D deficiency is common and associated with mortality in chronic kidney disease (CKD) patients. Cardiovascular disease (CVD) is the commonest cause of mortality in CKD patients. In a randomized, double blind, placebo controlled trial, we have recently reported favorable effects of vitamin D supplementation on vascular & endothelial function ... Read more >>

J. Steroid Biochem. Mol. Biol. (The Journal of steroid biochemistry and molecular biology)
[2018, 180:19-22]

Cited: 3 times

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