Full Text Journal Articles by
Author Madzouka B Kokolo

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Effect of sirolimus on malignancy and survival after kidney transplantation: systematic review and meta-analysis of individual patient data.

Greg A Knoll, Madzouka B Kokolo, Ranjeeta Mallick, Andrew Beck, Chieny D Buenaventura, Robin Ducharme, Rashad Barsoum, Corrado Bernasconi, Tom D Blydt-Hansen, Henrik Ekberg, Claudia R Felipe, John Firth, Lorenzo Gallon, Marielle Gelens, Denis Glotz, Jan Gossmann, Markus Guba, Ahmed Ali Morsy, Rebekka Salgo, Earnst H Scheuermann, Helio Tedesco-Silva, Stefan Vitko, Christopher Watson, Dean A Fergusson,

<h4>Objective</h4>To examine risk of malignancy and death in patients with kidney transplant who receive the immunosuppressive drug sirolimus.<h4>Design</h4>Systematic review and meta-analysis of individual patient data.<h4>Data sources</h4>Medline, Embase, and the Cochrane Central Register of Controlled Trials from inception to March 2013.<h4>Eligibility</h4>Randomized controlled trials comparing immunosuppressive regimens with and without sirolimus in ... Read more >>

BMJ (BMJ (Clinical research ed.))
[2014, 349:g6679]

Cited: 80 times

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The effects of lysine analogs during pelvic surgery: a systematic review and meta-analysis.

Rodney H Breau, Madzouka B Kokolo, Nahid Punjani, Ilias Cagiannos, Andrew Beck, Naomi Niznick, Chieny Buenaventura, Juthaporn Cowan, Gregory Knoll, Franco Momoli, Chris Morash, Marcel Ruzicka, Svetlana Schachkina, Alan Tinmouth, Hai Yan Xie, Dean A Fergusson,

Pelvic vasculature is complex and inconsistent while pelvic bones impede access to pelvic organs. These anatomical characteristics render pelvic surgery inherently difficult, and some of these procedures are frequently associated with blood loss that necessitates blood transfusion. The aim of this study was to review the literature on the use ... Read more >>

Transfus Med Rev (Transfusion medicine reviews)
[2014, 28(3):145-155]

Cited: 4 times

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Effectiveness and safety of thiotepa as conditioning treatment prior to stem cell transplant in patients with central nervous system lymphoma.

Madzouka B Kokolo, Dean Fergusson, Joseph O'Neill, Jason Tay, Alan T Tinmouth, Douglas Stewart, Chris Bredeson,

<h4>Background</h4>Thiothepa is a cytostatic agent used in managing solid malignancies, and also as conditioning treatment before hematopoietic stem cell transplantation [HSCT]. This systematic review summarizes evidence on its effectiveness and safety, in patients with central nervous system [CNS] lymphoma.<h4>Methods</h4>We searched 3 databases for clinical studies. When feasible, we performed meta-analyses.<h4>Results</h4>We ... Read more >>

Leuk Lymphoma (Leukemia & lymphoma)
[2014, 55(12):2712-2720]

Cited: 1 time

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Spot urine protein measurements in kidney transplantation: a systematic review of diagnostic accuracy.

Ayub Akbari, Dean Fergusson, Madzouka B Kokolo, Tim Ramsay, Andrew Beck, Robin Ducharme, Marcel Ruzicka, Amanda Grant-Orser, Christine A White, Greg A Knoll,

<h4>Background</h4>Quantification of proteinuria (albuminuria) in renal transplant recipients is important for diagnostic and prognostic purposes. Recent guidelines have recommended quantification of proteinuria by spot protein-to-creatinine ratio (PCR) or spot albumin-to-creatinine ratio (ACR). Validity of spot measurements remains unclear in renal transplant recipients.<h4>Methods</h4>Systematic review of adult kidney transplant recipients. Studies that ... Read more >>

Nephrol Dial Transplant (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2014, 29(4):919-926]

Cited: 3 times

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Accuracy of cystatin C-based estimates of glomerular filtration rate in kidney transplant recipients: a systematic review.

Gavin Harman, Ayub Akbari, Swapnil Hiremath, Christine A White, Tim Ramsay, Madzouka B Kokolo, Jeffery Craig, Greg A Knoll,

<h4>Background</h4>As with creatinine, cystatin C can be incorporated into a formula to estimate the glomerular filtration rate (GFR). The overall performance of cystatin C-based equations in kidney transplantation is unclear with conflicting results between studies.<h4>Methods</h4>Systematic review of adult kidney transplant recipients. Studies that reported mean bias (mean difference between the ... Read more >>

Nephrol Dial Transplant (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2013, 28(3):741-757]

Cited: 21 times

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HIV pre-exposure prophylaxis (PrEP)--a quantitative ethics appraisal.

Madzouka B Kokolo, Dean A Fergusson, D William Cameron,

<h4>Background</h4>There is now strong evidence that preventive oral antiretroviral therapy can moderately reduce likelihood of HIV infection. This concept is called HIV pre-exposure prophylaxis (PrEP). Premature closures of some previous PrEP clinical trials, secondary to ethical concerns, did not stop research. We aimed to appraise the extent of ethics considerations ... Read more >>

PLoS One (PloS one)
[2011, 6(8):e22497]

Cited: 3 times

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