Full Text Journal Articles by
Author M Capra

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Leptomeningeal Relapse of Embryonal Rhabdomyosarcoma after 15 years.

S Chew, J P Gleeson, A McCarthy, G A Watson, R O'Dwyer, S Nicholson, M Capra, C Owens, M McDermott, P Daly, C Grant,

Aim Rhabdomyosarcoma (RMS) is the most common malignant soft tissue tumour of childhood. We present the case of a late relapse of RMS to the leptomeninges after 15 years. Methods A 20 year old male presented with a 3 week history of headaches and nausea. He previously had RMS of ... Read more >>

Ir Med J (Irish medical journal)
[2020, 112(10):1026]

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Method for the production of pure and C-doped nanoboron powders tailored for superconductive applications.

Marco Capra, Federico Loria, Cristina Bernini, Gianmarco Bovone, Alice Moros, Michael Stöger-Pollach, Thomas Schachinger, Johannes Bernardi, Antonio Sergio Siri, Maurizio Vignolo,

The present paper describes the improvement of the performances of boron powder obtained applying the freeze-drying process (FDP) for the nanostructuration and doping of B2O3, which is here used as boron precursor. After the nanostructuration process, B2O3 is reduced to elemental nanoboron (nB) through magnesiothermic reaction with Mg. For this ... Read more >>

Nanotechnology (Nanotechnology)
[2020, 31(49):494001]

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ShcD Binds DOCK4, Promotes Ameboid Motility and Metastasis Dissemination, Predicting Poor Prognosis in Melanoma.

Ewa Aladowicz, Letizia Granieri, Federica Marocchi, Simona Punzi, Giuseppina Giardina, Pier Francesco Ferrucci, Giovanni Mazzarol, Maria Capra, Giuseppe Viale, Stefano Confalonieri, Sara Gandini, Fiorenza Lotti, Luisa Lanfrancone,

Metastases are the primary cause of cancer-related deaths. The underlying molecular and biological mechanisms remain, however, elusive, thus preventing the design of specific therapies. In melanomas, the metastatic process is influenced by the acquisition of metastasis-associated mutational and epigenetic traits and the activation of metastatic-specific signaling pathways in the primary ... Read more >>

Cancers (Basel) (Cancers)
[2020, 12(11):]

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Safe Perinatal Management of Neonates Born to SARS-CoV-2 Positive Mothers at the Epicenter of the Italian Epidemic.

Giacomo Biasucci, Giuseppe Cannalire, Akamin Raymond, Maria Elena Capra, Belinda Benenati, Giovanni Vadacca, Roberta Schiavo, Cristiana Pavesi, Renza Bonini,

Introduction: 2019-novel Coronavirus Disease (COVID-19) pandemic has recently struck Northern Italy. Limited data are available about COVID-19 during pregnancy and infancy, mostly from China. Herein, our experience on a safe perinatal management of neonates born to COVID-19 mothers is reported. Method: Since late February through May 15, 2020, 375 pregnant ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:565522]

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Newly diagnosed and previously treated multicentric Castleman disease respond equally to siltuximab.

Frits van Rhee, Jean-François Rossi, David Simpson, Alexander Fosså, Angela Dispenzieri, John Kuruvilla, Yeow Tee Goh, Seok-Goo Cho, Marcelo Capra, Ting Liu, Corey Casper, James Cavet, Raymond S Wong,

Br J Haematol (British journal of haematology)
[2020, :]

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Isatuximab as monotherapy and combined with dexamethasone in patients with relapsed/refractory multiple myeloma.

Meletios A Dimopoulos, Sara Bringhen, Pekka M Anttila, Marcelo Capra, Michele Cavo, Craig Emmitt Cole, Cristina Gasparetto, Vania Tietsche de Moraes Hungria, Matthew W Jenner, Vladimir I Vorobyev, Eduardo Patricio Yanez Ruiz, Jian Y Yin, Rao Saleem, Maeva Hellet, Sandrine Macé, Bruno Paiva, Ravi Vij,

This Phase 2 study evaluated isatuximab as monotherapy or combined with dexamethasone in relapsed/refractory multiple myeloma (RRMM). Patients had RRMM refractory to an immunomodulatory drug (IMiD) and a proteasome inhibitor (PI) or had received ≥3 prior lines of therapy incorporating an IMiD and PI. Patients received isatuximab either as monotherapy ... Read more >>

Blood (Blood)
[2020, :]

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Neonatal abstinence syndrome and intra-uterine growth restriction secondary to maternal antimigraine drug abuse.

Marco Cirronis, Giulia M Vezzoni, Nicoletta G DePaulis, Maria E Capra, Giacomo Biasucci, Carlo A Locatelli,

Basic Clin Pharmacol Toxicol (Basic & clinical pharmacology & toxicology)
[2020, :]

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Assessing the Feasibility of Augmenting Fall Detection Systems by Relying on UWB-Based Position Tracking and a Home Robot.

Maurizio Capra, Stefano Sapienza, Paolo Motto Ros, Alessio Serrani, Maurizio Martina, Alessandro Puiatti, Paolo Bonato, Danilo Demarchi,

Falls in the home environment are a primary cause of injury in older adults. According to the U.S. Centers for Disease Control and Prevention, every year, one in four adults 65 years of age and older reports experiencing a fall. A variety of different technologies have been proposed to detect ... Read more >>

Sensors (Basel) (Sensors (Basel, Switzerland))
[2020, 20(18):]

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Chronic lymphocytic leukemia cells impair osteoblastogenesis and promote osteoclastogenesis: role of TNFα, IL-6 and IL-11 cytokines.

Paolo Giannoni, Cecilia Marini, Giovanna Cutrona, Serena Matis, Maria Cristina Capra, Francesca Puglisi, Paola Luzzi, Simona Pigozzi, Gabriele Gaggero, Antonino Neri, Katia Todoerti, Fortunato Morabito, Adalberto Ibatici, Maurizio Miglino, Micaela Bergamaschi, Silvia Bruno, Gian Mario Sambuceti, Jean Louis Ravetti, Manlio Ferrarini, Franco Fais, Daniela de Totero,

Bone skeletal alterations are no longer considered a rare event in Chronic Lymphocytic Leukemia (CLL), especially at more advanced stages of the disease. This study is aimed at elucidating the mechanisms underlying this phenomenon. Bone marrow stromal cells, induced to differentiate toward osteoblasts in osteogenic medium, appeared unable to complete ... Read more >>

Haematologica (Haematologica)
[2020, :]

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Daratumumab, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma: subgroup analysis of CASTOR based on cytogenetic risk.

Katja Weisel, Andrew Spencer, Suzanne Lentzsch, Hervé Avet-Loiseau, Tomer M Mark, Ivan Spicka, Tamas Masszi, Birgitta Lauri, Mark-David Levin, Alberto Bosi, Vania Hungria, Michele Cavo, Je-Jung Lee, Ajay Nooka, Hang Quach, Markus Munder, Cindy Lee, Wolney Barreto, Paolo Corradini, Chang-Ki Min, Asher A Chanan-Khan, Noemi Horvath, Marcelo Capra, Meral Beksac, Roberto Ovilla, Jae-Cheol Jo, Ho-Jin Shin, Pieter Sonneveld, Tineke Casneuf, Nikki DeAngelis, Himal Amin, Jon Ukropec, Rachel Kobos, Maria-Victoria Mateos,

BACKGROUND:Multiple myeloma (MM) patients with high cytogenetic risk have poor outcomes. In CASTOR, daratumumab plus bortezomib/dexamethasone (D-Vd) prolonged progression-free survival (PFS) versus bortezomib/dexamethasone (Vd) alone and exhibited tolerability in patients with relapsed or refractory MM (RRMM). METHODS:This subgroup analysis evaluated D-Vd versus Vd in CASTOR based on cytogenetic risk, determined ... Read more >>

J Hematol Oncol (Journal of hematology & oncology)
[2020, 13(1):115]

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Phylogenetic reconstruction of breast cancer reveals two routes of metastatic dissemination associated with distinct clinical outcome.

David Venet, Danai Fimereli, Françoise Rothé, Bram Boeckx, Marion Maetens, Samira Majjaj, Ghizlane Rouas, Maria Capra, Giuseppina Bonizzi, Federica Contaldo, Christine Galant, Martine Piccart, Giancarlo Pruneri, Denis Larsimont, Diether Lambrechts, Christine Desmedt, Christos Sotiriou,

BACKGROUND:In breast cancer (BC), axillary lymph node (ALN) involvement is one of the strongest adverse prognostic factors. However, it is unclear whether loco-regional lymph node deposits are effectively the root of secondary metastases or only an indicator of competence of the primary tumour to spread to distant organs. METHODS:Here, we ... Read more >>

EBioMedicine (EBioMedicine)
[2020, 56:102793]

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Survival of childhood and adolescent/young adult (AYA) cancer patients in Ireland during 1994-2013: comparisons by age.

Scheryll Alken, Cormac Owens, Charles Gilham, Cliona Grant, Jane Pears, Sandra Deady, Aengus O'Marcaigh, Michael Capra, Deirdre O'Mahony, Owen Smith, Paul M Walsh,

BACKGROUND:Some studies indicate that survival of adolescents and young adults (AYA) with cancer may be inferior to that of younger children with similar cancers, possibly related (in part) to differences in access to centralized or standardized treatment. AIMS:This study aims to evaluate differences in survival for AYA patients when compared ... Read more >>

Ir J Med Sci (Irish journal of medical science)
[2020, 189(4):1223-1236]

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Global Retinoblastoma Presentation and Analysis by National Income Level.

, Ido Didi Fabian, Elhassan Abdallah, Shehu U Abdullahi, Rula A Abdulqader, Sahadatou Adamou Boubacar, Dupe S Ademola-Popoola, Adedayo Adio, Armin R Afshar, Priyanka Aggarwal, Ada E Aghaji, Alia Ahmad, Marliyanti N R Akib, Lamis Al Harby, Mouroge H Al Ani, Aygun Alakbarova, Silvia Alarcón Portabella, Safaa A F Al-Badri, Ana Patricia A Alcasabas, Saad A Al-Dahmash, Amanda Alejos, Ernesto Alemany-Rubio, Amadou I Alfa Bio, Yvania Alfonso Carreras, Christiane Al-Haddad, Hamoud H Y Al-Hussaini, Amany M Ali, Donjeta B Alia, Mazin F Al-Jadiry, Usama Al-Jumaily, Hind M Alkatan, Charlotta All-Eriksson, Ali A R M Al-Mafrachi, Argentino A Almeida, Khalifa M Alsawidi, Athar A S M Al-Shaheen, Entissar H Al-Shammary, Primawita O Amiruddin, Romanzo Antonino, Nicholas J Astbury, Hatice T Atalay, La-Ongsri Atchaneeyasakul, Rose Atsiaya, Taweevat Attaseth, Than H Aung, Silvia Ayala, Baglan Baizakova, Julia Balaguer, Ruhengiz Balayeva, Walentyna Balwierz, Honorio Barranco, Covadonga Bascaran, Maja Beck Popovic, Raquel Benavides, Sarra Benmiloud, Nissrine Bennani Guebessi, Rokia C Berete, Jesse L Berry, Anirban Bhaduri, Sunil Bhat, Shelley J Biddulph, Eva M Biewald, Nadia Bobrova, Marianna Boehme, H C Boldt, Maria Teresa B C Bonanomi, Norbert Bornfeld, Gabrielle C Bouda, Hédi Bouguila, Amaria Boumedane, Rachel C Brennan, Bénédicte G Brichard, Jassada Buaboonnam, Patricia Calderón-Sotelo, Doris A Calle Jara, Jayne E Camuglia, Miriam R Cano, Michael Capra, Nathalie Cassoux, Guilherme Castela, Luis Castillo, Jaume Català-Mora, Guillermo L Chantada, Shabana Chaudhry, Sonal S Chaugule, Argudit Chauhan, Bhavna Chawla, Violeta S Chernodrinska, Faraja S Chiwanga, Tsengelmaa Chuluunbat, Krzysztof Cieslik, Ruellyn L Cockcroft, Codruta Comsa, Zelia M Correa, Maria G Correa Llano, Timothy W Corson, Kristin E Cowan-Lyn, Monika Csóka, Xuehao Cui, Isac V Da Gama, Wantanee Dangboon, Anirban Das, Sima Das, Jacquelyn M Davanzo, Alan Davidson, Patrick De Potter, Karina Q Delgado, Hakan Demirci, Laurence Desjardins, Rosdali Y Diaz Coronado, Helen Dimaras, Andrew J Dodgshun, Craig Donaldson, Carla R Donato Macedo, Monica D Dragomir, Yi Du, Magritha Du Bruyn, Kemala S Edison, I Wayan Eka Sutyawan, Asmaa El Kettani, Amal M Elbahi, James E Elder, Dina Elgalaly, Alaa M Elhaddad, Moawia M Ali Elhassan, Mahmoud M Elzembely, Vera A Essuman, Ted Grimbert A Evina, Zehra Fadoo, Adriana C Fandiño, Mohammad Faranoush, Oluyemi Fasina, Delia D P G Fernández, Ana Fernández-Teijeiro, Allen Foster, Shahar Frenkel, Ligia D Fu, Soad L Fuentes-Alabi, Brenda L Gallie, Moira Gandiwa, Juan L Garcia, David García Aldana, Pascale Y Gassant, Jennifer A Geel, Fariba Ghassemi, Ana V Girón, Zelalem Gizachew, Marco A Goenz, Aaron S Gold, Maya Goldberg-Lavid, Glen A Gole, Nir Gomel, Efren Gonzalez, Graciela Gonzalez Perez, Liudmira González-Rodríguez, Henry N Garcia Pacheco, Jaime Graells, Liz Green, Pernille A Gregersen, Nathalia D A K Grigorovski, Koffi M Guedenon, D Sanjeeva Gunasekera, Ahmet K Gündüz, Himika Gupta, Sanjiv Gupta, Theodora Hadjistilianou, Patrick Hamel, Syed A Hamid, Norhafizah Hamzah, Eric D Hansen, J William Harbour, M Elizabeth Hartnett, Murat Hasanreisoglu, Sadiq Hassan, Shadab Hassan, Stanislava Hederova, Jose Hernandez, Lorelay Marie Carcamo Hernandez, Laila Hessissen, Diriba F Hordofa, Laura C Huang, G B Hubbard, Marlies Hummlen, Kristina Husakova, Allawi N Hussein Al-Janabi, Russo Ida, Vesna R Ilic, Vivekaraj Jairaj, Irfan Jeeva, Helen Jenkinson, Xunda Ji, Dong Hyun Jo, Kenneth P Johnson, William J Johnson, Michael M Jones, Theophile B Amani Kabesha, Rolande L Kabore, Swathi Kaliki, Abubakar Kalinaki, Mehmet Kantar, Ling-Yuh Kao, Tamar Kardava, Rejin Kebudi, Tomas Kepak, Naama Keren-Froim, Zohora J Khan, Hussain A Khaqan, Phara Khauv, Wajiha J Kheir, Vikas Khetan, Alireza Khodabande, Zaza Khotenashvili, Jonathan W Kim, Jeong Hun Kim, Hayyam Kiratli, Tero T Kivelä, Artur Klett, Jess Elio Kosh Komba Palet, Dalia Krivaitiene, Mariana Kruger, Kittisak Kulvichit, Mayasari W Kuntorini, Alice Kyara, Eva S Lachmann, Carol P S Lam, Geoffrey C Lam, Scott A Larson, Slobodanka Latinovic, Kelly D Laurenti, Bao Han A Le, Karin Lecuona, Amy A Leverant, Cairui Li, Ben Limbu, Quah Boon Long, Juan P López, Robert M Lukamba, Livia Lumbroso, Sandra Luna-Fineman, Delfitri Lutfi, Lesia Lysytsia, George N Magrath, Amita Mahajan, Abdul Rahim Majeed, Erika Maka, Mayuri Makan, Emil K Makimbetov, Chatonda Manda, Nieves Martín Begue, Lauren Mason, John O Mason, Ibrahim O Matende, Miguel Materin, Clarissa C D S Mattosinho, Marchelo Matua, Ismail Mayet, Freddy B Mbumba, John D McKenzie, Aurora Medina-Sanson, Azim Mehrvar, Aemero A Mengesha, Vikas Menon, Gary John V D Mercado, Marilyn B Mets, Edoardo Midena, Divyansh K C Mishra, Furahini G Mndeme, Ahmed A Mohamedani, Mona T Mohammad, Annette C Moll, Margarita M Montero, Rosa A Morales, Claude Moreira, Prithvi Mruthyunjaya, Mchikirwa S Msina, Gerald Msukwa, Sangeeta S Mudaliar, Kangwa I Muma, Francis L Munier, Gabriela Murgoi, Timothy G Murray, Kareem O Musa, Asma Mushtaq, Hamzah Mustak, Okwen M Muyen, Gita Naidu, Akshay Gopinathan Nair, Larisa Naumenko, Paule Aïda Ndoye Roth, Yetty M Nency, Vladimir Neroev, Hang Ngo, Rosa M Nieves, Marina Nikitovic, Elizabeth D Nkanga, Henry Nkumbe, Murtuza Nuruddin, Mutale Nyaywa, Ghislaine Obono-Obiang, Ngozi C Oguego, Andrzej Olechowski, Scott C N Oliver, Peter Osei-Bonsu, Diego Ossandon, Manuel A Paez-Escamilla, Halimah Pagarra, Sally L Painter, Vivian Paintsil, Luisa Paiva, Bikramjit P Pal, Mahesh Shanmugam Palanivelu, Ruzanna Papyan, Raffaele Parrozzani, Manoj Parulekar, Claudia R Pascual Morales, Katherine E Paton, Katarzyna Pawinska-Wasikowska, Jacob Pe'er, Armando Peña, Sanja Peric, Chau T M Pham, Remezo Philbert, David A Plager, Pavel Pochop, Rodrigo A Polania, Vladimir G Polyakov, Manca T Pompe, Jonathan J Pons, Daphna Prat, Vireak Prom, Ignatius Purwanto, Ali O Qadir, Seema Qayyum, Jiang Qian, Ardizal Rahman, Salman Rahman, Jamalia Rahmat, Purnima Rajkarnikar, Rajesh Ramanjulu, Aparna Ramasubramanian, Marco A Ramirez-Ortiz, Léa Raobela, Riffat Rashid, M Ashwin Reddy, Ehud Reich, Lorna A Renner, David Reynders, Dahiru Ribadu, Mussagy M Riheia, Petra Ritter-Sovinz, Duangnate Rojanaporn, Livia Romero, Soma R Roy, Raya H Saab, Svetlana Saakyan, Ahmed H Sabhan, Mandeep S Sagoo, Azza M A Said, Rohit Saiju, Beatriz Salas, Sonsoles San Román Pacheco, Gissela L Sánchez, Phayvanh Sayalith, Trish A Scanlan, Amy C Schefler, Judy Schoeman, Ahad Sedaghat, Stefan Seregard, Rachna Seth, Ankoor S Shah, Shawkat A Shakoor, Manoj K Sharma, Sadik T Sherief, Nandan G Shetye, Carol L Shields, Sorath Noorani Siddiqui, Sidi Sidi Cheikh, Sónia Silva, Arun D Singh, Niharika Singh, Usha Singh, Penny Singha, Rita S Sitorus, Alison H Skalet, Hendrian D Soebagjo, Tetyana Sorochynska, Grace Ssali, Andrew W Stacey, Sandra E Staffieri, Erin D Stahl, Christina Stathopoulos, Branka Stirn Kranjc, David K Stones, Caron Strahlendorf, Maria Estela Coleoni Suarez, Sadia Sultana, Xiantao Sun, Meryl Sundy, Rosanne Superstein, Eddy Supriyadi, Supawan Surukrattanaskul, Shigenobu Suzuki, Karel Svojgr, Fatoumata Sylla, Gevorg Tamamyan, Deborah Tan, Alketa Tandili, Fanny F Tarrillo Leiva, Maryam Tashvighi, Bekim Tateshi, Edi S Tehuteru, Luiz F Teixeira, Kok Hoi Teh, Tuyisabe Theophile, Helen Toledano, Doan L Trang, Fousseyni Traoré, Sumalin Trichaiyaporn, Samuray Tuncer, Harba Tyau-Tyau, Ali B Umar, Emel Unal, Ogul E Uner, Steen F Urbak, Tatiana L Ushakova, Rustam H Usmanov, Sandra Valeina, Milo van Hoefen Wijsard, Adisai Varadisai, Liliana Vasquez, Leon O Vaughan, Nevyana V Veleva-Krasteva, Nishant Verma, Andi A Victor, Maris Viksnins, Edwin G Villacís Chafla, Vicktoria Vishnevskia-Dai, Tushar Vora, Antonio E Wachtel, Werner Wackernagel, Keith Waddell, Patricia D Wade, Amina H Wali, Yi-Zhuo Wang, Avery Weiss, Matthew W Wilson, Amelia D C Wime, Atchareeya Wiwatwongwana, Damrong Wiwatwongwana, Charlotte Wolley Dod, Phanthipha Wongwai, Daoman Xiang, Yishuang Xiao, Jason C Yam, Huasheng Yang, Jenny M Yanga, Muhammad A Yaqub, Vera A Yarovaya, Andrey A Yarovoy, Huijing Ye, Yacoub A Yousef, Putu Yuliawati, Arturo M Zapata López, Ekhtelbenina Zein, Chengyue Zhang, Yi Zhang, Junyang Zhao, Xiaoyu Zheng, Katsiaryna Zhilyaeva, Nida Zia, Othman A O Ziko, Marcia Zondervan, Richard Bowman,

Importance:Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives:To report the retinoblastoma ... Read more >>

JAMA Oncol (JAMA oncology)
[2020, 6(5):685-695]

Cited: 1 time

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Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.

Matthew Clarke, Alan Mackay, Britta Ismer, Jessica C Pickles, Ruth G Tatevossian, Scott Newman, Tejus A Bale, Iris Stoler, Elisa Izquierdo, Sara Temelso, Diana M Carvalho, Valeria Molinari, Anna Burford, Louise Howell, Alex Virasami, Amy R Fairchild, Aimee Avery, Jane Chalker, Mark Kristiansen, Kelly Haupfear, James D Dalton, Wilda Orisme, Ji Wen, Michael Hubank, Kathreena M Kurian, Catherine Rowe, Mellissa Maybury, Stephen Crosier, Jeffrey Knipstein, Ulrich Schüller, Uwe Kordes, David E Kram, Matija Snuderl, Leslie Bridges, Andrew J Martin, Lawrence J Doey, Safa Al-Sarraj, Christopher Chandler, Bassel Zebian, Claire Cairns, Rachael Natrajan, Jessica K R Boult, Simon P Robinson, Martin Sill, Ira J Dunkel, Stephen W Gilheeney, Marc K Rosenblum, Debbie Hughes, Paula Z Proszek, Tobey J Macdonald, Matthias Preusser, Christine Haberler, Irene Slavc, Roger Packer, Ho-Keung Ng, Shani Caspi, Mara Popović, Barbara Faganel Kotnik, Matthew D Wood, Lissa Baird, Monika Ashok Davare, David A Solomon, Thale Kristin Olsen, Petter Brandal, Michael Farrell, Jane B Cryan, Michael Capra, Michael Karremann, Jens Schittenhelm, Martin U Schuhmann, Martin Ebinger, Winand N M Dinjens, Kornelius Kerl, Simone Hettmer, Torsten Pietsch, Felipe Andreiuolo, Pablo Hernáiz Driever, Andrey Korshunov, Lotte Hiddingh, Barbara C Worst, Dominik Sturm, Marc Zuckermann, Olaf Witt, Tabitha Bloom, Clare Mitchell, Evelina Miele, Giovanna Stefania Colafati, Francesca Diomedi-Camassei, Simon Bailey, Andrew S Moore, Timothy E G Hassall, Stephen P Lowis, Maria Tsoli, Mark J Cowley, David S Ziegler, Matthias A Karajannis, Kristian Aquilina, Darren R Hargrave, Fernando Carceller, Lynley V Marshall, Andreas von Deimling, Christof M Kramm, Stefan M Pfister, Felix Sahm, Suzanne J Baker, Angela Mastronuzzi, Andrea Carai, Maria Vinci, David Capper, Sergey Popov, David W Ellison, Thomas S Jacques, David T W Jones, Chris Jones,

Infant high-grade gliomas appear clinically distinct from their counterparts in older children, indicating that histopathologic grading may not accurately reflect the biology of these tumors. We have collected 241 cases under 4 years of age, and carried out histologic review, methylation profiling, and custom panel, genome, or exome sequencing. After ... Read more >>

Cancer Discov (Cancer discovery)
[2020, 10(7):942-963]

Cited: 2 times

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Steerable-Discrete-Cosine-Transform (SDCT): Hardware Implementation and Performance Analysis.

Riccardo Peloso, Maurizio Capra, Luigi Sole, Massimo Ruo Roch, Guido Masera, Maurizio Martina,

In the last years, the need for new efficient video compression methods grown rapidly as frame resolution has increased dramatically. The Joint Collaborative Team on Video Coding (JCT-VC) effort produced in 2013 the H.265/High Efficiency Video Coding (HEVC) standard, which represents the state of the art in video coding standards. ... Read more >>

Sensors (Basel) (Sensors (Basel, Switzerland))
[2020, 20(5):]

Cited: 0 times

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RARE-45. ACTIVITY OF LAROTRECTINIB IN TRK FUSION CANCER PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM TUMORS

Francois Doz, Birgit Geoerger, Steven G DuBois, Juneko E Grilley-Olson, Cornelis M van Tilburg, Antoine Italiano, Andrej Lissat, Hyoung Jin Kang, Makoto Tahara, Valentina Boni, Sebastien Perreault, Michael Capra, Shivani Nanda, Nicoletta Brega, Ariadna Holynskyj, David S Ziegler, David S Hong, David M Hyman, Alexander Drilon,

Abstract BACKGROUND TRK fusions are oncogenic drivers of a variety of tumors, many of which can involve the central nervous system (CNS). Larotrectinib is a selective TRK inhibitor FDA-approved for the treatment of TRK fusion cancers (Drilon et al., NEJM 2018). Here we report on the clinical activity of larotrectinib ... Read more >>

Neuro Oncol (Neuro-oncology)
[2019, 21(Suppl 6):vi231-vi231]

Cited: 0 times

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Correction for Danovi et al., "Amplification of Mdmx (or Mdm4) Directly Contributes to Tumor Formation by Inhibiting p53 Tumor Suppressor Activity".

Davide Danovi, Erik Meulmeester, Diego Pasini, Domenico Migliorini, Maria Capra, Ruth Frenk, Petra de Graaf, Sarah Francoz, Patrizia Gasparini, Alberto Gobbi, Kristian Helin, Pier Giuseppe Pelicci, Aart G Jochemsen, Jean-Christophe Marine,

Mol Cell Biol (Molecular and cellular biology)
[2019, 39(15):]

Cited: 0 times

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Paediatric malignant melanoma in Ireland: A population study and review of the literature.

Christine S Quinlan, Michael Capra, Marlese Dempsey,

INTRODUCTION:Malignant melanoma is increasing in frequency worldwide; however, this disease is rare in children. As large-scale studies on paediatric melanoma are lacking, management is currently often based upon the understanding of the disease process in adults. The aim of this study was to characterise cases of paediatric melanoma diagnosed in ... Read more >>

J Plast Reconstr Aesthet Surg (Journal of plastic, reconstructive & aesthetic surgery : JPRAS)
[2019, 72(8):1388-1395]

Cited: 0 times

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Efficacy of low-level laser for treatment of cancer oral mucositis: a systematic review and meta-analysis.

Fernando Anschau, Jacqueline Webster, Marcelo Eduardo Zanella Capra, André Luis Ferreira de Azeredo da Silva, Airton Tetelbom Stein,

Review effectiveness of low-level laser therapy (LLLT) in the curative treatment of oral mucositis (OM) in patients receiving cancer therapy. A systematic review with meta-analysis was performed using Medline, Embase, and Cochrane Library databases according to PRISMA guidelines, to identify randomized controlled trials (RCT) on OM in patients during and/or ... Read more >>

Lasers Med Sci (Lasers in medical science)
[2019, 34(6):1053-1062]

Cited: 2 times

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Content validity of the WorkHab functional capacity evaluation.

Carole James, Lynette MacKenzie, Mike Capra,

INTRODUCTION:Validity is a dynamic process and as part of a continual process of evaluation of tools, this study aimed to evaluate content validity of the WorkHab functional capacity evaluation, a tool used in occupational rehabilitation. METHODS:A cross sectional survey of health professionals who conduct FCEs investigated their ratings of item ... Read more >>

Aust Occup Ther J (Australian occupational therapy journal)
[2019, 66(3):380-392]

Cited: 0 times

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Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort.

Sigbjørn Smeland, Stefan S Bielack, Jeremy Whelan, Mark Bernstein, Pancras Hogendoorn, Mark D Krailo, Richard Gorlick, Katherine A Janeway, Fiona C Ingleby, Jakob Anninga, Imre Antal, Carola Arndt, Ken L B Brown, Trude Butterfass-Bahloul, Gabriele Calaminus, Michael Capra, Catharina Dhooge, Mikael Eriksson, Adrienne M Flanagan, Godehard Friedel, Mark C Gebhardt, Hans Gelderblom, Robert Goldsby, Holcombe E Grier, Robert Grimer, Douglas S Hawkins, Stefanie Hecker-Nolting, Kirsten Sundby Hall, Michael S Isakoff, Gordana Jovic, Thomas Kühne, Leo Kager, Thekla von Kalle, Edita Kabickova, Susanna Lang, Ching C Lau, Patrick J Leavey, Stephen L Lessnick, Leo Mascarenhas, Regine Mayer-Steinacker, Paul A Meyers, Raj Nagarajan, R Lor Randall, Peter Reichardt, Marleen Renard, Catherine Rechnitzer, Cindy L Schwartz, Sandra Strauss, Lisa Teot, Beate Timmermann, Matthew R Sydes, Neyssa Marina,

BACKGROUND:High-grade osteosarcoma is a primary malignant bone tumour mainly affecting children and young adults. The European and American Osteosarcoma Study (EURAMOS)-1 is a collaboration of four study groups aiming to improve outcomes of this rare disease by facilitating randomised controlled trials. METHODS:Patients eligible for EURAMOS-1 were aged ≤40 years with ... Read more >>

Eur. J. Cancer (European journal of cancer (Oxford, England : 1990))
[2019, 109:36-50]

Cited: 27 times

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Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial.

Meletios A Dimopoulos, Francesca Gay, Fredrik Schjesvold, Meral Beksac, Roman Hajek, Katja Christina Weisel, Hartmut Goldschmidt, Vladimir Maisnar, Philippe Moreau, Chang Ki Min, Agnieszka Pluta, Wee-Joo Chng, Martin Kaiser, Sonja Zweegman, Maria-Victoria Mateos, Andrew Spencer, Shinsuke Iida, Gareth Morgan, Kaveri Suryanarayan, Zhaoyang Teng, Tomas Skacel, Antonio Palumbo, Ajeeta B Dash, Neeraj Gupta, Richard Labotka, S Vincent Rajkumar, ,

BACKGROUND:Maintenance therapy following autologous stem cell transplantation (ASCT) can delay disease progression and prolong survival in patients with multiple myeloma. Ixazomib is ideally suited for maintenance therapy given its convenient once-weekly oral dosing and low toxicity profile. In this study, we aimed to determine the safety and efficacy of ixazomib ... Read more >>

Lancet (Lancet (London, England))
[2019, 393(10168):253-264]

Cited: 17 times

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Scurvy: an unusual complication of paediatric cancer treatment.

Iain Irvine, Triona Walshe, Michael Capra, Roisin Hayes,

Scurvy is a disease that is rarely encountered in modern medicine. A condition that was classically associated with sailors, its incidence has decreased dramatically since the discovery of its association with vitamin C deficiency. We present the case of a 2-year-old boy, whose treatment for neuroblastoma was complicated by gastrointestinal ... Read more >>

Skeletal Radiol (Skeletal radiology)
[2019, 48(6):995-998]

Cited: 0 times

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Frontline bortezomib, rituximab, cyclophosphamide, doxorubicin, and prednisone (VR-CAP) versus rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in transplantation-ineligible patients with newly diagnosed mantle cell lymphoma: final overall survival results of a randomised, open-label, phase 3 study.

Tadeusz Robak, Jie Jin, Halyna Pylypenko, Gregor Verhoef, Noppadol Siritanaratkul, Johannes Drach, Markus Raderer, Jiri Mayer, Juliana Pereira, Gayane Tumyan, Rumiko Okamoto, Susumu Nakahara, Peter Hu, Carlos Appiani, Sepideh Nemat, Franco Cavalli, ,

BACKGROUND:In the LYM-3002 study, the efficacy and safety of frontline bortezomib plus rituximab, cyclophosphamide, doxorubicin, and prednisone (VR-CAP) and rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) were compared in transplant-ineligible patients with untreated, newly diagnosed, mantle cell lymphoma. We report the final overall survival and safety outcomes for patients in ... Read more >>

Lancet Oncol. (The Lancet. Oncology)
[2018, 19(11):1449-1458]

Cited: 9 times

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Pharmacokinetics and Exposure-Response Analyses of Daratumumab in Combination Therapy Regimens for Patients with Multiple Myeloma.

Xu Steven Xu, Meletios A Dimopoulos, Pieter Sonneveld, P Joy Ho, Andrew Belch, Merav Leiba, Marcelo Capra, David Gomez, Eva Medvedova, Shinsuke Iida, Chang-Ki Min, Jordan Schecter, Richard Jansson, Liping Zhang, Yu-Nien Sun, Pamela L Clemens,

INTRODUCTION:Daratumumab, a human IgG monoclonal antibody targeting CD38, has demonstrated activity as monotherapy and in combination with standard-of-care regimens in multiple myeloma. Population pharmacokinetic analyses were conducted to determine the pharmacokinetics of intravenous daratumumab in combination therapy versus monotherapy, evaluate the effect of patient- and disease-related covariates on drug disposition, ... Read more >>

Adv Ther (Advances in therapy)
[2018, 35(11):1859-1872]

Cited: 4 times

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