Full Text Journal Articles by
Author Lynn M Alaeddine


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Pharmacological regulation of cytochrome P450 metabolites of arachidonic acid attenuates cardiac injury in diabetic rats.

Lynn M Alaeddine, Frederic Harb, Maysaa Hamza, Batoul Dia, Nahed Mogharbil, Nadim S Azar, Mohamed H Noureldein, Mirella El Khoury, Ramzi Sabra, Assaad A Eid,

Diabetic cardiomyopathy (DCM) is a well-established complication of type 1 and type 2 diabetes associated with a high rate of morbidity and mortality. DCM is diagnosed at advanced and irreversible stages. Therefore, it is of utmost need to identify novel mechanistic pathways involved at early stages to prevent or reverse ... Read more >>

Transl Res (Translational research : the journal of laboratory and clinical medicine)
[2021, 235:85-101]

Cited: 1 time

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Metformin: A Growing Journey from Glycemic Control to the Treatment of Alzheimer's Disease and Depression.

Mohamed El Massry, Lynn M Alaeddine, Leen Ali, Celine Saad, Assaad A Eid,

Metabolic stress, transduced as an altered cellular redox and energy status, presents as the main culprit in many diseases, including diabetes. However, its role in the pathology of neurological disorders is still not fully elucidated. Metformin, a biguanide compound, is an FDA approved antidiabetic drug generally used for the treatment ... Read more >>

Curr Med Chem (Current medicinal chemistry)
[2021, 28(12):2328-2345]

Cited: 3 times

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