Full Text Journal Articles by
Author Lukman Mustapha

Advertisement

Find full text journal articles








Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor.

Augustine A Ahmadu, Claire Delehouzé, Anas Haruna, Lukman Mustapha, Bilqis A Lawal, Aniefiok Udobre, Blandine Baratte, Camilla Triscornia, Axelle Autret, Thomas Robert, Jeannette Chloë Bulinski, Morgane Rousselot, Mélanie Simoes Eugénio, Marie-Thérèse Dimanche-Boitrel, Jacobus P Petzer, Lesetja J Legoabe, Stéphane Bach,

The purpose of this work is to investigate the protein kinase inhibitory activity of constituents from <i>Acacia auriculiformis</i> stem bark. Column chromatography and NMR spectroscopy were used to purify and characterize betulin from an ethyl acetate soluble fraction of acacia bark. Betulin, a known inducer of apoptosis, was screened against ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2021, 26(15):]

Cited: 0 times

View full text PDF listing >>



Current Status of Endoplasmic Reticulum Stress in Type II Diabetes.

Sagir Mustapha, Mustapha Mohammed, Ahmad Khusairi Azemi, Abubakar Ibrahim Jatau, Aishatu Shehu, Lukman Mustapha, Ibrahim Muazzamu Aliyu, Rabi'u Nuhu Danraka, Abdulbasit Amin, Auwal Adam Bala, Wan Amir Nizam Wan Ahmad, Aida Hanum Ghulam Rasool, Mohd Rais Mustafa, Siti Safiah Mokhtar,

The endoplasmic reticulum (ER) plays a multifunctional role in lipid biosynthesis, calcium storage, protein folding, and processing. Thus, maintaining ER homeostasis is essential for cellular functions. Several pathophysiological conditions and pharmacological agents are known to disrupt ER homeostasis, thereby, causing ER stress. The cells react to ER stress by initiating ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2021, 26(14):]

Cited: 1 time

View full text PDF listing >>



Advertisement

Current Status of Endoplasmic Reticulum Stress in Type II Diabetes

Sagir Mustapha, Mustapha Mohammed, Ahmad Khusairi Azemi, Abubakar Ibrahim Jatau, Aishatu Shehu, Lukman Mustapha, Ibrahim Muazzamu Aliyu, Rabi’u Nuhu Danraka, Abdulbasit Amin, Auwal Adam Bala, Wan Amir Nizam Wan Ahmad, Aida Hanum Ghulam Rasool, Mohd Rais Mustafa, Siti Safiah Mokhtar,

The endoplasmic reticulum (ER) plays a multifunctional role in lipid biosynthesis, calcium storage, protein folding, and processing. Thus, maintaining ER homeostasis is essential for cellular functions. Several pathophysiological conditions and pharmacological agents are known to disrupt ER homeostasis, thereby, causing ER stress. The cells react to ER stress by initiating ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2021, 26(14):]

Cited: 0 times

View full text PDF listing >>



Current Status of Endoplasmic Reticulum Stress in Type II Diabetes

Sagir Mustapha, Mustapha Mohammed, Ahmad Khusairi Azemi, Abubakar Ibrahim Jatau, Aishatu Shehu, Lukman Mustapha, Muazzamu Aliyu, Rabi’u Nuhu Danraka, Abdulbasit Amin, Auwal Adam Bala, Wan Amir Nizam Wan Ahmad, Aida Hanum Ghulam Rasool, Mohd Rais Mustafa, Siti Safiah Mokhtar,

The endoplasmic reticulum (ER) plays a multifunctional role in lipid biosynthesis, calcium storage, protein folding, and processing. Thus, maintaining ER homeostasis in insulin-secreting beta-cells is essential. Several pathophysiological conditions and pharmacological agents disrupt the ER homeostasis, thereby causing ER stress. The cells react to ER stress by initiating an adaptive ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Betulin, a Newly Characterized Compound in Acacia Auriculiformis Bark, is a Multi-target Protein Kinase Inhibitor

Augustine Ahmadu, Claire Delehouzé, Anas Haruna, Lukman Mustapha, Bilqis Lawal, Aniefiok Udobre, Blandine Baratte, Camilla Triscornia, Axelle Autret, Thomas Robert, Jeannette Chloë Bulinski, Morgane Rousselot, Mélanie Simoes Eugénio, Marie-Thérèse Dimanche-Boitrel, Jacobus Petzer, Lesetja Legoabe, Stéphane Bach,

The purpose of this work is to investigate the protein kinase inhibitory activity of constituents from ethyl acetate soluble fraction of Acacia auriculiformis stem bark. Column chromatography, gel filtration and NMR spectroscopy were used to purified and characterized betulin from the extract. Betulin which is a known inducer of apoptosis ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>





Advertisement


Disclaimer

0.6492 s