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Author Luigi Di Biase

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Catheter ablation of frequent monomorphic ventricular arrhythmias in Andersen-Tawil syndrome: case report and focused literature review.

Roberto Keegan, Leonardo Onetto, Franco Gregorietti, Ricardo Urruti, Luigi Di Biase,

<h4>Background/purpose</h4>Andersen-Tawil syndrome type 1 is a rare autosomal dominant disease caused by a KCNJ2 gene mutation and clinically characterized by dysmorphic features, periodic muscular paralysis, and frequent ventricular arrhythmias (VAs). Although polymorphic and bidirectional ventricular tachycardias are prevalent, PVCs are the most frequent VAs. In addition, a "dominant" morphology with ... Read more >>

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2021, :]

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Half-Dose Direct Oral Anticoagulation Versus Standard Antithrombotic Therapy After Left Atrial Appendage Occlusion.

Domenico G Della Rocca, Michele Magnocavallo, Luigi Di Biase, Sanghamitra Mohanty, Chintan Trivedi, Nicola Tarantino, Carola Gianni, Carlo Lavalle, Christoffel Johannes Van Niekerk, Jorge Romero, David F Briceño, Mohamed Bassiouny, Amin Al-Ahmad, J David Burkhardt, Veronica N Natale, G Joseph Gallinghouse, Armando Del Prete, Giovanni B Forleo, Javier Sanchez, Dhanunjaya Lakkireddy, Rodney P Horton, Douglas N Gibson, Andrea Natale,

<h4>Objectives</h4>This study evaluated the long-term efficacy of a standard antithrombotic strategy versus half-dose direct oral anticoagulation (DOAC) after Watchman implantation.<h4>Background</h4>No consensus currently exists on the selection of the most effective antithrombotic strategy to prevent device-related thrombosis (DRT) in patients undergoing endocardial left atrial appendage closure.<h4>Methods</h4>After successful left atrial appendage closure, ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2021, 14(21):2353-2364]

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Prevalence, Outcomes, and Management of Ventricular Arrhythmias in COVID-19 Patients

Nicola Tarantino, Domenico G. Della Rocca, Fengwei Zou, Aung Lin, Andrea Natale, Luigi Di Biase,

Synopsis We review the current data on epidemiology, the clinical significance, the pathophysiologic mechanisms, and the treatment of VAs in the setting of COVID-19. VAs prevail in 0.15-8% of in hospitalized patients, but only sustained and rapid tachyarrhythmias are purportedly associated with a significant increase in mortality. Multiple factors can ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

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Cardiopulmonary Support During Catheter Ablation of Ventricular Arrhythmias With Hemodynamic Instability: The Role of Inducibility.

Massimo Grimaldi, Maria Monica Marino, Nicola Vitulano, Federico Quadrini, Federica Troisi, Nicola Caporusso, Vera Perniciaro, Rosa Caruso, Nicola Duni, Giacomo Cecere, Alberto Martinelli, Pietro Guida, Vito Del Monte, Tommaso Langialonga, Luigi Di Biase, Antonio Di Monaco,

<b>Background:</b> Catheter ablation is a treatment option for sustained ventricular tachycardias (VTs) that are refractory to pharmacological treatment; however, patients with fast VT and electrical storm (ES) are at risk for cardiogenic shock. We report our experience using cardiopulmonary support with extracorporeal membrane oxygenation (ECMO) during catheter ablation of VT. ... Read more >>

Front Cardiovasc Med (Frontiers in cardiovascular medicine)
[2021, 8:747858]

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Effects of opioid receptor agonist and antagonist medications on electrocardiogram changes and presentation of cardiac arrhythmia: review article.

Farshid Etaee, Morgan Tobin, Suchith Vuppala, Alireza Komaki, Brian P Delisle, Luigi Di Biase, John N Catanzaro, Andrea Natale, Claude S Elayi,

Mortality associated with prescription opioids has significantly increased over the past few decades and is considered a global pandemic. Prescribed opioids can cause cardiac arrhythmias, leading to fatal outcomes and unexpected death, even in the absence of structural cardiac disease. Despite the extent of cardiac toxicity and death associated with ... Read more >>

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2021, :]

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Recovery of Conduction Following High-Power Short-Duration Ablation in Patients With Atrial Fibrillation: A Single-Center Experience.

Sanghamitra Mohanty, Chintan Trivedi, Domenico G Della Rocca, Carola Gianni, Bryan MacDonald, Angel Quintero Mayedo, Amin Al-Ahmad, John D Burkhardt, Mohamed Bassiouny, G Joseph Gallinghouse, Rodney Horton, Luigi Di Biase, Andrea Natale,

[Figure: see text]. ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2021, 14(10):e010096]

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Endomyocardial Biopsy: The Forgotten Piece in the Arrhythmogenic Cardiomyopathy Puzzle.

Michela Casella, Marco Bergonti, Antonio Dello Russo, Riccardo Maragna, Alessio Gasperetti, Paolo Compagnucci, Valentina Catto, Filippo Trombara, Antonio Frappampina, Edoardo Conte, Marco Fogante, Elena Sommariva, Stefania Rizzo, Monica De Gaspari, Andrea Giovagnoni, Daniele Andreini, Giulio Pompilio, Luigi Di Biase, Andrea Natale, Cristina Basso, Claudio Tondo,

Background Endomyocardial biopsy (EMB) is part of 2010 Task Force Criteria (TFC) for arrhythmogenic right ventricular cardiomyopathy (ARVC). However, its usage has been curtailed because of its low presumed diagnostic yield, and it is now a poorly used tool. This study aims to analyze the contribution of EMB to the ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2021, 10(19):e021370]

Cited: 1 time

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Ventricular arrhythmias in athletes: Role of a comprehensive diagnostic workup.

Antonio Dello Russo, Paolo Compagnucci, Michela Casella, Alessio Gasperetti, Stefania Riva, Maria Antonietta Dessanai, Francesca Pizzamiglio, Valentina Catto, Federico Guerra, Giulia Stronati, Daniele Andreini, Gianluca Pontone, Alice Bonomi, Stefania Rizzo, Luigi Di Biase, Alessandro Capucci, Andrea Natale, Cristina Basso, Cesare Fiorentini, Paolo Zeppilli, Claudio Tondo,

<h4>Background</h4>Ventricular arrhythmias (VAs) represent a critical issue with regard to sports eligibility assessment in athletes. The ideal diagnostic evaluation of competitive and leisure-time athletes with complex VAs has not been clearly defined.<h4>Objective</h4>The purpose of this study was to assess the clinical implications of invasive electrophysiological assessments and endomyocardial biopsy (EMB) ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, :]

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Targeting non-pulmonary vein triggers in persistent atrial fibrillation: results from a prospective, multicentre, observational registry.

Domenico G Della Rocca, Luigi Di Biase, Sanghamitra Mohanty, Chintan Trivedi, Carola Gianni, Jorge Romero, Nicola Tarantino, Michele Magnocavallo, Mohamed Bassiouny, Veronica N Natale, Angel Quintero Mayedo, Bryan Macdonald, Carlo Lavalle, Ghulam Murtaza, Krishna Akella, Giovanni B Forleo, Amin Al-Ahmad, John David Burkhardt, Gerald Joseph Gallinghouse, Javier E Sanchez, Rodney P Horton, Juan F Viles-Gonzalez, Dhanunjaya Lakkireddy, Andrea Natale,

<h4>Aims</h4>We evaluated the efficacy of an ablation strategy empirically targeting pulmonary veins (PVs) and posterior wall (PW) and the prevalence and clinical impact of extrapulmonary trigger inducibility and ablation in a large cohort of patients with persistent atrial fibrillation (PerAF).<h4>Methods and results</h4>A total of 1803 PerAF patients were prospectively enrolled. ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2021, :]

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RETRACTED:B-AB03-04 CEREBRAL MICROEMBOLIC SIGNAL BURDEN DURING PULSED FILED ABLATION: PRELIMINARY RESULTS FROM ROBOTICALLY ASSISTED TRANSCRANIAL DOPPLER.

Andrea Natale, Domenico G Della Rocca, Carola Gianni, Chintan G Trivedi, Rodney P Horton, Mohamed A Bassiouny, Amin Al-Ahmad, G Joseph Gallinghouse, J David Burkhardt, Luigi Di Biase, Sanghamitra Mohanty,

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the authors. The authors inadvertently specified some ablation settings in the methods section that should not have been reported because they can be potentially linked to a specific ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(8S):S5-S6]

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Clinical presentation, diagnosis, and treatment of atrioesophageal fistula resulting from atrial fibrillation ablation.

Domenico G Della Rocca, Michele Magnocavallo, Veronica N Natale, Carola Gianni, Sanghamitra Mohanty, Chintan Trivedi, Carlo Lavalle, Giovanni B Forleo, Nicola Tarantino, Jorge Romero, Xiadong Zhang, Mohamed Bassiouny, Amin Al-Ahmad, David J Burkhardt, Joseph G Gallinghouse, Javier E Sanchez, Rodney P Horton, Luigi Di Biase, Andrea Natale,

<h4>Background</h4>Atrioesophageal fistula (AEF) is a worrisome complication of atrial fibrillation (AF) ablation. Its clinical manifestations and time course are unpredictable and may contribute to diagnostic and treatment delays. We conducted a systematic review of all available cases of AEF, aiming at characterizing clinical presentation, time course, diagnostic pitfalls, and outcomes.<h4>Methods</h4>The ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2021, 32(9):2441-2450]

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B-PO03-160 OUTCOMES IN PATIENTS WITH COVID-19 INFECTION AND T-WAVE INVERSIONS: A PROPENSITY SCORE-MATCHED ANALYSIS

Luigi Di Biase, Dhanunjaya R. Lakkireddy, Isabella Alviz, David F. Briceno, Abhishek Jaiswal, Dalvert Polanco, Juan C. Diaz, Daniel Rodriguez, Mohamed Gabr, Chintan G. Trivedi, Sanghamitra Mohanty, Domenico G. Della Rocca, Andrea Natale, Jorge Romero,

Heart Rhythm (Heart rhythm)
[2021, 18(8):S254-S254]

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Sinus Node Sparing Hybrid Thoracoscopic Ablation Outcomes in Patients with Inappropriate Sinus Tachycardia (SUSRUTA-IST) Registry.

Dhanunjaya Lakkireddy, Jalaj Garg, Carlo DeAsmundis, Mark LaMeier, Ahmed Romeya, Justin Vanmeetren, Peter Park, Rangarao Tummala, Scott Koerber, Chandra Vasamreddy, Alap Shah, Poojita Shivamurthy, Ken Frazier, Yashi Awasthi, Gian Battista Chierchia, Donita Atkins, Sudha Bommana, Luigi Di Biase, Amin Al-Ahmad, Andrea Natale, Rakesh Gopinathannair,

<h4>Background</h4>Medical treatment of inappropriate sinus tachycardia (IST) remains suboptimal. Radiofrequency sinus node (RF-SN) ablation has poor success and higher complication rates.<h4>Objective</h4>We aimed to compare clinical outcomes of the novel SN sparing hybrid ablation technique with those of RF-SN modification for IST management.<h4>Methods</h4>This is a multicenter prospective registry comparing the SN ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, :]

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Safety/Efficacy of DOAC Versus Aspirin for Reduction of Risk of Cerebrovascular Events Following VT Ablation.

Dhanunjaya Lakkireddy, Jayaprakash Shenthar, Jalaj Garg, Deepak Padmanabhan, Rakesh Gopinathannair, Luigi Di Biase, Jorge Romero, Sanghamitra Mohanty, David J Burkhardt, Amin Al-Ahmad, Donita Atkins, Sudha Bommana, Andrea Natale,

<h4>Objectives</h4>The STROKE-VT (Safety and Efficacy of Direct Oral Anticoagulant Versus Aspirin for Reduction of Risk of Cerebrovascular Events in Patients Undergoing Ventricular Tachycardia Ablation) study is a multicenter, randomized controlled trial that examined the differences in cerebrovascular events between direct oral anticoagulant (DOAC) and aspirin (ASA) use postprocedurally in patients ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, :]

Cited: 2 times

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Pulsed field catheter ablation in atrial fibrillation.

Luigi Di Biase, Juan Carlos Diaz, Xiao-Dong Zhang, Jorge Romero,

Catheter ablation (CA) has become the mainstay therapy for the maintenance of sinus rhythm in patients with atrial fibrillation (AF), with pulmonary vein isolation (PVI) the most frequently used treatment strategy. Although several energy sources have been tested (including radiofrequency, cryothermal and laser), these are not devoid of safety issues ... Read more >>

Trends Cardiovasc Med (Trends in cardiovascular medicine)
[2021, :]

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RETRACTED:B-PO04-095 ESOPHAGEAL TEMPERATURE MONITORING DURING ATRIAL FIBRILLATION ABLATION WITH THE PULSED FIELD ABLATION SYSTEM.

Andrea Natale, Domenico G Della Rocca, Carola Gianni, Chintan G Trivedi, Amin Al-Ahmad, Mohamed A Bassiouny, G Joseph Gallinghouse, Rodney P Horton, J David Burkhardt, Luigi Di Biase, Sanghamitra Mohanty,

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the authors. The authors inadvertently specified some ablation settings in the methods section that should not have been reported because they can be potentially linked to a specific ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(8S):S318]

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Wide-area antral pulmonary vein and posterior wall isolation by way of segmental nonocclusive applications using a novel radiofrequency ablation balloon.

Arash Aryana, Shelley L Allen, Luigi Di Biase, Mark R Bowers, Padraig Gearoid O'Neill, Andrea Natale,

HeartRhythm Case Rep (HeartRhythm case reports)
[2021, 7(8):518-521]

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Radiofrequency Energy Applications Targeting Significant Residual Leaks After Watchman Implantation: A Prospective, Multicenter Experience.

Domenico G Della Rocca, Ghulam Murtaza, Luigi Di Biase, Krishna Akella, Subramaniam C Krishnan, Michele Magnocavallo, Sanghamitra Mohanty, Carola Gianni, Chintan Trivedi, Carlo Lavalle, Giovanni B Forleo, Veronica N Natale, Nicola Tarantino, Jorge Romero, Rakesh Gopinathannair, Philip J Patel, Mohamed Bassiouny, Armando Del Prete, Amin Al-Ahmad, J David Burkhardt, G Joseph Gallinghouse, Javier E Sanchez, Shephal K Doshi, Rodney P Horton, Dhanunjaya Lakkireddy, Andrea Natale,

<h4>Objectives</h4>The aim of this study was to evaluate the efficacy of radiofrequency (RF) energy applications targeting the atrial side of a significant residual leak in patients with acute and chronic evidence of incomplete percutaneous left atrial appendage (LAA) occlusion.<h4>Background</h4>RF applications have been proved to prevent recanalization of intracranial aneurysms after ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, :]

Cited: 1 time

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Subcutaneous implantable cardioverter-defibrillator and defibrillation testing: A propensity-matched pilot study.

Giovanni B Forleo, Alessio Gasperetti, Alexander Breitenstein, Mikael Laredo, Marco Schiavone, Matteo Ziacchi, Julia Vogler, Danilo Ricciardi, Pietro Palmisano, Agostino Piro, Paolo Compagnucci, Xavier Waintraub, Gianfranco Mitacchione, Gianmarco Carrassa, Giulia Russo, Silvana De Bonis, Andrea Angeletti, Antonio Bisignani, Francesco Picarelli, Michela Casella, Edoardo Bressi, Giovanni Rovaris, Leonardo Calò, Luca Santini, Carlo Pignalberi, Carlo Lavalle, Maurizio Viecca, Ennio Pisanò, Iacopo Olivotto, Antonio Curnis, Antonio Dello Russo, Claudio Tondo, Charles J Love, Luigi Di Biase, Jan Steffel, Roland Tilz, Nicolas Badenco, Mauro Biffi,

<h4>Background</h4>To date, only a few comparisons between subcutaneous implantable cardioverter-defibrillator (S-ICD) patients undergoing and those not undergoing defibrillation testing (DT) at implantation (DT+ vs DT-) have been reported.<h4>Objective</h4>The purpose of this study was to compare long-term clinical outcomes of 2 propensity-matched cohorts of DT+ and DT- patients.<h4>Methods</h4>Among consecutive S-ICD patients ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(12):2072-2079]

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Incidence of new-onset atrial fibrillation in COVID-19 is associated with increased epicardial adipose tissue.

Leandro Slipczuk, Francesco Castagna, Alison Schonberger, Eitan Novogrodsky, Damini Dey, Ulrich P Jorde, Jeffrey M Levsky, Luigi Di Biase, Mario J Garcia,

<h4>Purpose</h4>Coronary artery calcium (CAC) and epicardial adipose tissue (EAT) can predict AF in the general population. We aimed to determine if CAC and EAT measured by computed tomographic (CT) scanning can predict new-onset AF in patients admitted with COVID-19 disease.<h4>Methods</h4>We performed a retrospective, post hoc analysis of all patients admitted ... Read more >>

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2021, :]

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Incidence of Device-Related Thrombosis in Watchman Patients Undergoing a Genotype-Guided Antithrombotic Strategy.

Domenico G Della Rocca, Rodney P Horton, Luigi Di Biase, Carola Gianni, Chintan Trivedi, Sanghamitra Mohanty, Alisara Anannab, Michele Magnocavallo, Qiong Chen, Nicola Tarantino, Mohamed Bassiouny, Carlo Lavalle, Veronica N Natale, Giovanni B Forleo, Armando Del Prete, Christoffel Johannes Van Niekerk, Amin Al-Ahmad, J David Burkhardt, G Joseph Gallinghouse, Javier E Sanchez, Dhanunjaya Lakkireddy, Douglas N Gibson, Andrea Natale,

<h4>Objectives</h4>This study sought to report the incidence of device-related thrombosis (DRT) and thromboembolic (TE) events when an alternative to clopidogrel is prescribed in loss-of-function (LOF) allele carriers of the cytochrome P450 2C19 (CYP2C19) gene.<h4>Background</h4>LOF polymorphisms of the CYP2C19 gene are associated with reduced hepatic bioactivation of clopidogrel.<h4>Methods</h4>One thousand two Watchman ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, :]

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Natural History of Arrhythmia After Successful Isolation of Pulmonary Veins, Left Atrial Posterior Wall, and Superior Vena Cava in Patients With Paroxysmal Atrial Fibrillation: A Multi-Center Experience.

Sanghamitra Mohanty, Chintan Trivedi, Pamela Horton, Domenico G Della Rocca, Carola Gianni, Bryan MacDonald, Angel Mayedo, Javier Sanchez, G Joseph Gallinghouse, Amin Al-Ahmad, Rodney P Horton, J David Burkhardt, Antonio Dello Russo, Michela Casella, Claudio Tondo, Sakis Themistoclakis, Giovanni Forleo, Luigi Di Biase, Andrea Natale,

Background We evaluated long-term outcome of isolation of pulmonary veins, left atrial posterior wall, and superior vena cava, including time to recurrence and prevalent triggering foci at repeat ablation in patients with paroxysmal atrial fibrillation with or without cardiovascular comorbidities. Methods and Results A total of 1633 consecutive patients with ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2021, 10(11):e020563]

Cited: 1 time

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Focal impulse and rotor modulation guided ablation versus pulmonary vein isolation for atrial fibrillation: A meta-analysis of head-to-head comparative studies.

Jorge Romero, Mohamed Gabr, Isabella Alviz, David Briceno, Juan Carlos Diaz, Daniel Rodriguez, Kavisha Patel, Dalvert Polanco, Chintan Trivedi, Sanghamitra Mohanty, Domenico Della Rocca, Dhanunjaya Lakkireddy, Andrea Natale, Luigi Di Biase,

<h4>Introduction</h4>Empirical pulmonary vein isolation (PVI) remains the cornerstone for catheter ablation of atrial fibrillation (AF). Various ablation strategies and modalities are continually tested with the aim of improving ablation outcomes. Although focal impulse and rotor modulation (FIRM)-guided ablation is currently used as an adjunct to PVI, evidence supporting this strategy ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2021, 32(7):1822-1832]

Cited: 1 time

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Intracardiac Echocardiography to Guide Catheter Ablation of Atrial Fibrillation.

Carola Gianni, Javier E Sanchez, Domenico G Della Rocca, Amin Al-Ahmad, Rodney P Horton, Luigi Di Biase, Andrea Natale,

Intracardiac echocardiography (ICE) is a valuable tool and should be standard of care in any modern electrophysiology laboratory. Through real-time imaging of cardiac anatomy, ICE is used to guide electrophysiology procedures and monitor for complications. This article is a short overview of the application of real-time ICE imaging during atrial ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, 13(2):303-311]

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Role of immunosuppressive therapy in the management refractory postprocedural pericarditis.

Bharat Narasimhan, Mohit K Turagam, Jalaj Garg, Domenico G Della Rocca, Rakesh Gopinathannair, Luigi Di Biase, Jorge Romero, Sanghamitra Mohanty, Andrea Natale, Dhanunjaya Lakkireddy,

<h4>Objective</h4>To assess the safety and efficacy of a novel immunosuppressive regimen-combination Methotrexate/Prednisone (cMtx/P)-in the management of severe refractory rPPP.<h4>Methods</h4>In this multicenter, nonrandomized, retrospective, observational study, 408 consecutive patients diagnosed with persistent rPPP between 2017 and 19 were included. Patients with refractory symptoms despite 3 months of conventional therapy were initiated ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2021, 32(8):2165-2170]

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