Full Text Journal Articles by
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Response to Comment on Paolisso et al. Impact of Admission Hyperglycemia on Heart Failure Events and Mortality in Patients With Takotsubo Syndrome at Long-term Follow-up: Data From HIGH-GLUCOTAKO Investigators. Diabetes Care 2021;44:2158-2161.

Pasquale Paolisso, Luca Bergamaschi, Pietro Rambaldi, Gianluca Gatta, Alberto Foà, Francesco Angeli, Michele Fabrizio, Gianni Casella, Michelangela Barbieri, Nazzareno Galiè, Raffaele Marfella, Carmine Pizzi, Celestino Sardu,

Diabetes Care (Diabetes care)
[2021, 44(11):e201-e202]

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Echocardiography in COVID-19 pandemic: clinical findings and the importance of emerging technology

Alberto Barosi, Luca Bergamaschi, Ignazio Cusmano, Alessio Gasperetti, Marco Schiavone, Elisa Gherbesi,

SYNOPSIS Coronavirus disease 2019 (COVID-19) could have a direct or indirect effect on the cardiovascular system. To detect cardiac involvement, trans-thoracic echocardiography (TTE), as a widely available and cost-effective tool, is highly recommended and can provide important information that can affect the clinical management of COVID-19 patients. Despite that, considering ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

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Arrhythmogenic Risk and Mechanisms of QT Prolonging Drugs to Treat COVID-19

Marco Schiavone, Alessio Gasperetti, Elisa Gherbesi, Luca Bergamaschi, Roberto Arosio, Gianfranco Mitacchione, Maurizio Viecca, Giovanni B. Forleo,

While looking for a “magic bullet” to treat COVID-19, the massive off-label use of several of drugs in COVID-19, including repurposed antimalarial drugs, immunosuppressive agents, anti-virals and antibacterial agents, have generated concerns in the early phase of the pandemic due a possible arrhythmogenic effects in relation to QTc interval prolongation. ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

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Langerhans cell histiocytosis in adults: a retrospective, single-center case series.

Stefano Chiaravalli, Andrea Ferrari, Luca Bergamaschi, Nadia Puma, Giovanna Gattuso, Giovanna Sironi, Olga Nigro, Virginia Livellara, Elisabetta Schiavello, Veronica Biassoni, Marta Podda, Cristina Meazza, Filippo Spreafico, Michela Casanova, Monica Terenziani, Roberto Luksch, Maura Massimino,

Langerhans cell histiocytosis is rare in adults, and most of what we know about its diagnosis and treatment comes from pediatric studies. We report clinical findings and results of treatment in a retrospective series of 63 consecutive adult patients (18-76 years old), treated at our pediatric unit from 1990 to 2020 ... Read more >>

Ann Hematol (Annals of hematology)
[2021, :]

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Impact of admission hyperglycemia on short and long-term prognosis in acute myocardial infarction: MINOCA versus MIOCA.

Pasquale Paolisso, Alberto Foà, Luca Bergamaschi, Francesco Angeli, Michele Fabrizio, Francesco Donati, Sebastiano Toniolo, Chiara Chiti, Andrea Rinaldi, Andrea Stefanizzi, Matteo Armillotta, Angelo Sansonetti, Ilenia Magnani, Gianmarco Iannopollo, Paola Rucci, Gianni Casella, Nazzareno Galiè, Carmine Pizzi,

<h4>Background</h4>The prognostic role of hyperglycemia in patients with myocardial infarction and obstructive coronary arteries (MIOCA) is acknowledged, while data on non-obstructive coronary arteries (MINOCA) are still lacking. Recently, we demonstrated that admission stress-hyperglycemia (aHGL) was associated with a larger infarct size and inflammatory response in MIOCA, while no differences were ... Read more >>

Cardiovasc Diabetol (Cardiovascular diabetology)
[2021, 20(1):192]

Cited: 1 time

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Children and adolescent solid tumours and high-intensity end-of-life care: what can be done to reduce acute care admissions?

Marta Giorgia Podda, Elisabetta Schiavello, Carlo Alfredo Clerici, Roberto Luksch, Monica Terenziani, Andrea Ferrari, Michela Casanova, Filippo Spreafico, Cristina Meazza, Veronica Biassoni, Stefano Chiaravalli, Nadia Puma, Luca Bergamaschi, Giovanna Gattuso, Giovanna Sironi, Olga Nigro, Maura Massimino,

Despite improvements in survival, cancer remains the leading cause of non-accidental death in children and adolescents, who risk receiving high-intensity end-of-life (HI-EOL) care.<h4>Objective</h4>To analyse treatments for relapses (particularly in the last weeks of life), assess their impact on the EOL, identify patients most likely to receive HI-EOL care and examine ... Read more >>

BMJ Support Palliat Care (BMJ supportive & palliative care)
[2021, :]

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Correction to: Incidental finding of APC deletion in a child: double trouble or double chance? - a case report.

Erica Rosina, Berardo Rinaldi, Rosamaria Silipigni, Luca Bergamaschi, Giovanna Gattuso, Stefano Signoroni, Silvana Guerneri, Alessandra Carnevali, Paola Giovanna Marchisio, Donatella Milani,

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):185]

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Diagnostic approach for coronary microvascular dysfunction in patients with chest pain and no obstructive coronary artery disease.

Gaetano Antonio Lanza, Doralisa Morrone, Carmine Pizzi, Isabella Tritto, Luca Bergamaschi, Antonio De Vita, Angelo Villano, Filippo Crea,

A large number of studies has demonstrated that abnormalities of coronary microcirculation may be responsible for both acute and chronic cardiac ischemic syndromes. In clinical practice the microvascular origin of myocardial ischemia and angina is usually considered in patients who are found to have normal or near-normal coronary arteries at ... Read more >>

Trends Cardiovasc Med (Trends in cardiovascular medicine)
[2021, :]

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SARS-CoV-2 vaccination for adolescents and young adult patients treated at a specialist pediatric oncology unit.

Olga Nigro, Giovanna Sironi, Luca Bergamaschi, Giovanna Gattuso, Nadia Puma, Virginia Livellara, Stefano Chiaravalli, Andrea Ferrari, Maura Massimino,

This brief report describes the SARS-CoV-2 vaccination program at our pediatric oncology unit. Adopting Italian regulations, patients treated for cancer within the previous 6 months were offered vaccination with the Pfizer-BioNtech vaccine if aged ≥16 years, and with the Pfizer-BioNtech or Moderna vaccine if aged ≥18 years. From March 24 to April 28, ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68(10):e29240]

Cited: 1 time

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Neobladder and ablative pelvic radiotherapy: still a taboo?

Luca Bergamaschi, Marianna Alessandra Gerardi, Mattia Zaffaroni, Matteo Augugliaro, Sabrina Vigorito, Elena Rondi, Paolo Della Vigna, Gianluca Varano, Uberto Fumagalli Romario, Roberto Biffi, Edgardo Enrico Edoardo Picardi, Annamaria Ferrari, Barbara Alicja Jereczek-Fossa,

The presence of a neobladder constitutes a limitation for the radiation oncologist, as there is no clear evidence about its tolerance to radiotherapy (RT). The limited literature only concerns the conventional postoperative treatment in patients with bladder cancer after cystectomy. Here we report a case of a patient with neobladder ... Read more >>

Tumori (Tumori)
[2021, 107(6):NP108-NP113]

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Impact of Admission Hyperglycemia on Short and Long-Term Prognosis in Acute Myocardial Infarction: MINOCA versus MIOCA

Pasquale Paolisso, Alberto Foà, Luca Bergamaschi, Francesco Angeli, Michele Fabrizio, Francesco Donati, Toniolo Sebastiano, Chiti Chiara, Rinaldi Andrea, Andrea Stefanizzi, Matteo Armillotta, Angelo Sansonetti, Ilenia Magnani, Gianmarco Iannopollo, Paola Rucci, Casella Gianni, Nazzareno Galiè, Carmine Pizzi,

<h4>Background: </h4> The prognostic role of hyperglycemia in patients with myocardial infarction and obstructive coronary arteries (MIOCA) is acknowledged, while data on non-obstructive coronary arteries (MINOCA) are still lacking. Recently, we demonstrated that admission stress-hyperglycemia (aHGL) was associated with a larger infarct size and inflammatory response in MIOCA, while no ... Read more >>

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Impact of Admission Hyperglycemia on Heart Failure Events and Mortality in Patients With Takotsubo Syndrome at Long-term Follow-up: Data From HIGH-GLUCOTAKO Investigators.

Pasquale Paolisso, Luca Bergamaschi, Pietro Rambaldi, Gianluca Gatta, Alberto Foà, Francesco Angeli, Michele Fabrizio, Gianni Casella, Michelangela Barbieri, Nazzareno Galiè, Raffaele Marfella, Carmine Pizzi, Celestino Sardu,

<h4>Objective</h4>To investigate admission hyperglycemia effects on the sympathetic system and long-term prognosis in Takotsubo syndrome (TTS).<h4>Research design and methods</h4>In patients with TTS and hyperglycemia (n = 28) versus normoglycemia (n = 48), serum norepinephrine and <sup>123</sup>I-labeled metaiodobenzylguanidine (MIBG) cardiac scintigraphy were assessed. Heart failure (HF) occurrence and death events over ... Read more >>

Diabetes Care (Diabetes care)
[2021, 44(9):2158-2161]

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Exploring miRNA Signature and Other Potential Biomarkers for Oligometastatic Prostate Cancer Characterization: The Biological Challenge behind Clinical Practice. A Narrative Review.

Giulia Corrao, Mattia Zaffaroni, Luca Bergamaschi, Matteo Augugliaro, Stefania Volpe, Matteo Pepa, Giuseppina Bonizzi, Salvatore Pece, Nicola Amodio, Francesco Alessandro Mistretta, Stefano Luzzago, Gennaro Musi, Sarah Alessi, Francesco Maria La Fauci, Chiara Tordonato, Daniela Tosoni, Federica Cattani, Sara Gandini, Giuseppe Petralia, Gabriella Pravettoni, Ottavio De Cobelli, Giuseppe Viale, Roberto Orecchia, Giulia Marvaso, Barbara Alicja Jereczek-Fossa,

In recent years, a growing interest has been directed towards oligometastatic prostate cancer (OMPC), as patients with three to five metastatic lesions have shown a significantly better survival as compared with those harboring a higher number of lesions. The efficacy of local ablative treatments directed on metastatic lesions (metastases-directed treatments) ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(13):]

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Cutaneous melanoma in children and adolescents: The EXPeRT/PARTNER diagnostic and therapeutic recommendations.

Andrea Ferrari, Ricardo Lopez Almaraz, Yves Reguerre, Maja Cesen, Luca Bergamaschi, Alice Indini, Dominik T Schneider, Jan Godzinski, Ewa Bien, Teresa Stachowicz-Stencel, Thomas K Eigentler, Stefano Chiaravalli, Malgorzata A Krawczyk, Alberto Pappo, Daniel Orbach, Gianni Bisogno, Ines B Brecht,

Cutaneous melanoma is rare in children and, like other very rare pediatric tumors, it suffers from a shortage of knowledge and clinical expertise. The clinical management of pediatric melanoma is often challenging. Its clinical and pathological diagnosis may be difficult, and there is no standard treatment. In the absence of ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68 Suppl 4:e28992]

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Response of the Authors.

Luca Bergamaschi, Pasquale Paolisso, Francesco Angeli, Michele Fabrizio, Andrea Rinaldi, Alberto Foà, Carmine Pizzi,

Ann Noninvasive Electrocardiol (Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc)
[2021, 26(3):e12852]

Cited: 1 time

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Complexity index in sarcoma and genomic grade index gene signatures in rhabdomyosarcoma of pediatric and adult ages.

Andrea Ferrari, Maria Federica Iannó, Andrea Carenzo, Orazio Fortunato, Michela Casanova, Stefano Chiaravalli, Luca Bergamaschi, Rossella Bertulli, Francesca Cattaneo, Paola Collini, Annalisa Trama, Gabriella Sozzi, Maura Massimino, Loris De Cecco, Patrizia Gasparini,

<h4>Background</h4>Rhabdomyosarcoma (RMS), the most frequent soft-tissue sarcoma in childhood, shows extensive heterogeneity in histology, site and age of onset, clinical course, and prognosis. Adolescents and young adults (AYA) with RMS form a subgroup of patients whose survival lacks behind that of children while diagnosed with histologically similar tumors.<h4>Procedures</h4>A 67-gene prognostic ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68(7):e28987]

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COVID-19 and radiotherapy: impact on work and personal life of Lombardy residents during first lockdown, survey endorsed by AIRO Young.

Giulia Corrao, Luca Bergamaschi, Mattia Zaffaroni, Iacopo Cavallo, Giulia Marvaso, Daniela Alterio, Fabrizio Mastrilli, Silvio Capizzi, Isacco Desideri, Gabriella Pravettoni, Roberto Orecchia, Barbara Alicja Jereczek-Fossa,

<h4>Aim</h4>Since 20 February 2020, Lombardy has been one of the most affected areas worldwide by the coronavirus disease 2019 (COVID-19) pandemic. The aim of this study is to evaluate work and psychological impact of COVID-19 on Lombardy radiation therapy (RT) residents in the first 3 months of the outbreak (first ... Read more >>

Tumori (Tumori)
[2021, :3008916211000826]

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Oligorecurrent Prostate Cancer and Stereotactic Body Radiotherapy: Where Are We Now? A Systematic Review and Meta-analysis of Prospective Studies.

Giulia Marvaso, Stefania Volpe, Matteo Pepa, Matteo Augugliaro, Giulia Corrao, Annalisa Biffi, Mattia Zaffaroni, Luca Bergamaschi, Francesco Maria La Fauci, Francesco Alessandro Mistretta, Stefano Luzzago, Federica Cattani, Gennaro Musi, Giuseppe Petralia, Gabriella Pravettoni, Ottavio De Cobelli, Roberto Orecchia, Barbara Alicja Jereczek-Fossa,

<h4>Context</h4>The optimal management of oligometastatic prostate cancer (PCa) is still debated.<h4>Objective</h4>The purpose of the present systematic review and meta-analysis is to collect the available evidence to date to better define the role of stereotactic body radiotherapy (SBRT) in selected patients with oligorecurrent PCa.<h4>Evidence acquisition</h4>Study methodology complied with the Preferred Reporting ... Read more >>

Eur Urol Open Sci (European urology open science)
[2021, 27:19-28]

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Clues and pitfalls in the diagnostic approach to cardiac masses: are pseudo-tumours truly benign?

Alberto Foà, Pasquale Paolisso, Luca Bergamaschi, Paola Rucci, Luca Di Marco, Davide Pacini, Ornella Leone, Nazzareno Galié, Carmine Pizzi,

Eur J Prev Cardiol (European journal of preventive cardiology)
[2021, :]

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Multiagent chemotherapy including IrIVA regimen and maintenance therapy in the treatment of desmoplastic small round cell tumor.

Andrea Ferrari, Luca Bergamaschi, Stefano Chiaravalli, Emilia Pecori, Barbara Diletto, Ombretta Alessandro, Tommaso Giandini, Virginia Livellara, Giovanna Sironi, Michela Casanova,

This study reports the treatment feasibility and efficacy of a novel multiagent intensive treatment program for young patients with desmoplastic small round cell tumor. This small series includes three patients and should be seen as a first suggestion of integration of the dose density and the maintenance chemotherapy concept. The ... Read more >>

Tumori (Tumori)
[2021, :300891621995250]

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The value of ECG changes in risk stratification of COVID-19 patients.

Luca Bergamaschi, Emanuela Concetta D'Angelo, Pasquale Paolisso, Sebastiano Toniolo, Michele Fabrizio, Francesco Angeli, Francesco Donati, Ilenia Magnani, Andrea Rinaldi, Lorenzo Bartoli, Chiara Chiti, Mauro Biffi, Carmine Pizzi, Pierluigi Viale, Nazzareno Galié,

<h4>Background</h4>There is growing evidence of cardiac injury in COVID-19. Our purpose was to assess the prognostic value of serial electrocardiograms in COVID-19 patients.<h4>Methods</h4>We evaluated 269 consecutive patients admitted to our center with confirmed SARS-CoV-2 infection. ECGs available at admission and after 1 week from hospitalization were assessed. We evaluated the correlation ... Read more >>

Ann Noninvasive Electrocardiol (Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc)
[2021, 26(3):e12815]

Cited: 4 times

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Incidental finding of APC deletion in a child: double trouble or double chance? - a case report.

Erica Rosina, Berardo Rinaldi, Rosamaria Silipigni, Luca Bergamaschi, Giovanna Gattuso, Stefano Signoroni, Silvana Guerneri, Alessandra Carnevali, Paola Giovanna Marchisio, Donatella Milani,

<h4>Background</h4>22q11.2 deletion syndrome is one of the most common genomic disorders, characterized by the variable presence of facial dysmorphisms, congenital cardiac defects, velopharyngeal insufficiency/cleft palate, thymic hypoplasia/aplasia, immunodeficiency, parathyroid hypoplasia, developmental delay, learning disabilities, psychiatric disorders, renal, ocular, and skeletal malformations, hearing loss and laryngeal abnormalities. Chromosomal microarray (CMA) hybridization ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):31]

Cited: 1 time

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Hyperglycemia, Inflammatory Response and Infarct Size in Obstructive Acute Myocardial Infarction and MINOCA

Pasquale Paolisso, Alberto Foà, Luca Bergamaschi, Francesco Donati, Michele Fabrizio, Chiara Chiti, Francesco Angeli, Sebastiano Toniolo, Andrea Stefanizzi, Matteo Armillotta, Paola Rucci, Gianmarco Iannopollo, Gianni Casella, Cinzia Marrozzini, Nazzareno Galiè, Carmine Pizzi,

<h4>Background: </h4> Hyperglycemia has been associated with increased inflammatory indexes and larger infarct sizes in patients with obstructive acute myocardial infarction (obs-AMI). In contrast, no studies have explored these correlations in non-obstructive acute myocardial infarction (MINOCA). We investigated the relationship between hyperglycemia, inflammation and infarct size in a cohort of ... Read more >>

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Hyperglycemia, inflammatory response and infarct size in obstructive acute myocardial infarction and MINOCA.

Pasquale Paolisso, Alberto Foà, Luca Bergamaschi, Francesco Donati, Michele Fabrizio, Chiara Chiti, Francesco Angeli, Sebastiano Toniolo, Andrea Stefanizzi, Matteo Armillotta, Paola Rucci, Gianmarco Iannopollo, Gianni Casella, Cinzia Marrozzini, Nazzareno Galiè, Carmine Pizzi,

<h4>Background</h4>Hyperglycemia has been associated with increased inflammatory indexes and larger infarct sizes in patients with obstructive acute myocardial infarction (obs-AMI). In contrast, no studies have explored these correlations in non-obstructive acute myocardial infarction (MINOCA). We investigated the relationship between hyperglycemia, inflammation and infarct size in a cohort of AMI patients ... Read more >>

Cardiovasc Diabetol (Cardiovascular diabetology)
[2021, 20(1):33]

Cited: 9 times

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Medulloblastoma and familial adenomatous polyposis: Good prognosis and good quality of life in the long-term?

Maura Massimino, Stefano Signoroni, Luna Boschetti, Luisa Chiapparini, Alessandra Erbetta, Veronica Biassoni, Elisabetta Schiavello, Andrea Ferrari, Filippo Spreafico, Monica Terenziani, Stefano Chiaravalli, Nadia Puma, Luca Bergamaschi, Maria Teresa Ricci, Laura Cattaneo, Giovanna Gattuso, Francesca Romana Buttarelli, Francesca Gianno, Evelina Miele, Geraldina Poggi, Marco Vitellaro,

<h4>Introduction</h4>Mutations of the APC (adenomatous polyposis coli) gene correlate mainly with familial adenomatous polyposis (FAP), but can occasionally be pathogenic for medulloblastoma (MBL) wingless-related integration site (WNT) subtype, the course of which has only recently been described.<h4>Methods</h4>We retrieved all patients with documented germline APC mutations and a diagnosis of MBL ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68(4):e28912]

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