Full Text Journal Articles by
Author Lorenzo Conti

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Longitudinal prognostication in retroperitoneal sarcoma survivors: Development and external validation of two dynamic nomograms.

Dario Callegaro, Francesco Barretta, Carol J Swallow, Dirk C Strauss, Sylvie Bonvalot, Charles Honorè, Eberhard Stoeckle, Frits van Coevorden, Rick Haas, Piotr Rutkowski, Yvonne Schrage, Mark Fairweather, Lorenzo Conti, Nikolaos Vassos, Rebecca A Gladdy, Deanna Ng, Winan J van Houdt, Rosalba Miceli, Chandrajit P Raut, Alessandro Gronchi,

<h4>Purpose</h4>The aim of this study was to create and validate dynamic nomograms to predict overall survival (OS) and disease-free survival (DFS) at different time points during follow-up in patients who had undergone resection of primary retroperitoneal sarcoma (RPS).<h4>Methods</h4>Patients with primary RPS operated upon between 2002 and 2017 at four and six ... Read more >>

Eur J Cancer (European journal of cancer (Oxford, England : 1990))
[2021, 157:291-300]

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Functional and structural MRI correlates of executive functions in multiple sclerosis.

Olga Marchesi, Raffaello Bonacchi, Paola Valsasina, Paolo Preziosa, Elisabetta Pagani, Laura Cacciaguerra, Alessandro Meani, Lorenzo Conti, Damiano Mistri, Maria A Rocca, Massimo Filippi,

<h4>Background</h4>Executive dysfunctions, including difficulties in attention, working memory, planning, and inhibition affect 15%-28% of multiple sclerosis (MS) patients.<h4>Objectives</h4>To investigate structural and functional magnetic resonance imaging (MRI) abnormalities underlying executive function (EF) in MS patients.<h4>Methods</h4>A total 116 MS patients and 65 controls underwent resting-state (RS) and diffusion-weighted sequences and neuropsychological examination, ... Read more >>

Mult Scler (Multiple sclerosis (Houndmills, Basingstoke, England))
[2021, :13524585211033184]

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Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study.

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We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave ... Read more >>

Anaesthesia (Anaesthesia)
[2021, :]

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Unraveling the substrates of cognitive impairment in multiple sclerosis: A multiparametric structural and functional magnetic resonance imaging study.

Lorenzo Conti, Paolo Preziosa, Alessandro Meani, Elisabetta Pagani, Paola Valsasina, Olga Marchesi, Carmen Vizzino, Maria A Rocca, Massimo Filippi,

<h4>Background</h4>Cognitive impairment frequently affects multiple sclerosis (MS) patients. However, its neuroanatomical correlates still need to be fully explored. We investigated the contribution of structural and functional magnetic resonance imaging (MRI) abnormalities in explaining cognitive impairment in MS.<h4>Methods</h4>Brain dual-echo, diffusion tensor, 3D T1-weighted and resting-state (RS) MRI sequences were acquired from ... Read more >>

Eur J Neurol (European journal of neurology)
[2021, :]

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Morbidity and Outcomes After Distal Pancreatectomy for Primary Retroperitoneal Sarcoma: An Analysis by the Trans-Atlantic Australasian Retroperitoneal Sarcoma Working Group.

Sanjay P Bagaria, Carol Swallow, Harini Suraweera, Chandrajit P Raut, Mark Fairweather, Ferdinando Cananzi, Vittorio Quagliuolo, Giovanni Grignani, Daphne Hompes, Samuel J Ford, Carolyn Nessim, Sameer Apte, Jacek Skoczylas, Piotr Rutkowski, Sylvie Bonvalot, Dimitri Tzanis, Emmanuel Gabriel, Elisabetta Pennacchioli, Markus Albertsmeier, Robert J Canter, Raphael Pollock, Valerie Grignol, Kenneth Cardona, Adriana C Gamboa, Marko Novak, Eberhard Stoeckle, Martin Almquist, Nita Ahuja, Nicholas Klemen, Winan Van Houdt, David Gyorki, Alexandra Gangi, Marco Rastrelli, Jos van der Hage, Yvonne Schrage, Sergio Valeri, Lorenzo Conti, Matthew R Spiegel, Zhou Li, Marco Fiore, Alessandro Gronchi,

<h4>Background</h4>Multi-visceral resection often is used in the treatment of retroperitoneal sarcoma (RPS). The morbidity after distal pancreatectomy for primary pancreatic cancer is well-documented, but the outcomes after distal pancreatectomy for primary RPS are not. This study aimed to evaluate morbidity and oncologic outcomes after distal pancreatectomy for primary RPS.<h4>Methods</h4>In this ... Read more >>

Ann Surg Oncol (Annals of surgical oncology)
[2021, 28(11):6882-6889]

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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.

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<h4>Background</h4>Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.<h4>Methods</h4>The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an ... Read more >>

Br J Surg (The British journal of surgery)
[2021, :]

Cited: 15 times

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Strictureplasties performed by laparoscopic approach for complicated Crohn's disease. A prospective, observational, cohort study.

Gianluca M Sampietro, Francesco Colombo, Alice Frontali, Caterina Baldi, Lorenzo Conti, Dario Dilillo, Francesca Penagini, Manuela Nebuloni, Francesca D'Addio, Paolo Fiorina, Giovanni Maconi, Fabio Corsi, Gianvincenzo Zuccotti, Sandro Ardizzone, Diego Foschi,

<h4>Background</h4>Laparoscopy is considered the best surgical approach for Crohn's Disease (CD), and strictureplasty a reliable alternative to intestinal resection. Nevertheless, their association has never been evaluated.<h4>Aim</h4>To investigate feasibility and safety of conventional (SP) and non-conventional (NCSP) strictureplasties, using laparoscopy, for complicated CD.<h4>Methods</h4>Starting January 2008, a prospective cohort study was performed, ... Read more >>

Dig Liver Dis (Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver)
[2021, :]

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Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study.

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Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 ... Read more >>

Anaesthesia (Anaesthesia)
[2021, 76(6):748-758]

Cited: 34 times

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Effect of cognitive reserve on structural and functional MRI measures in healthy subjects: a multiparametric assessment.

Lorenzo Conti, Gianna C Riccitelli, Paolo Preziosa, Carmen Vizzino, Olga Marchesi, Maria A Rocca, Massimo Filippi,

<h4>Background</h4>Cognitive reserve (CR) contributes to inter-individual variability of cognitive performance and to preserve cognitive functioning facing aging and brain damage. However, brain anatomical and functional substrates of CR still need to be fully explored in young healthy subjects (HS). By evaluating a relatively large cohort of young HS, we investigated ... Read more >>

J Neurol (Journal of neurology)
[2021, 268(5):1780-1791]

Cited: 1 time

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Defining the role of neoadjuvant systemic therapy in high-risk retroperitoneal sarcoma: A multi-institutional study from the Transatlantic Australasian Retroperitoneal Sarcoma Working Group.

William W Tseng, Francesco Barretta, Lorenzo Conti, Giovanni Grignani, Francesco Tolomeo, Markus Albertsmeier, Martin K Angele, Piotr Rutkowski, Jacek Skoczylas, Antonino De Paoli, Federico Navarria, Chandrajit P Raut, Mark Fairweather, Jeffrey M Farma, Carolyn Nessim, Neha Goel, Valerie P Grignol, Samuel J Ford, Kenneth Cardona, Ty Subhawong, Hannah L Tattersall, Rachel M Lee, James S Hu, Margaret von Mehren, Roberta Sanfilippo, Alessandro Gronchi,

<h4>Background</h4>In patients with retroperitoneal sarcoma (RPS), the incidence of recurrence after surgery remains high. Novel treatment approaches are needed. This retrospective study evaluated patients with primary, high-risk RPS who received neoadjuvant systemic therapy followed by surgery to 1) determine the frequency and potential predictors of radiologic tumor responses and 2) ... Read more >>

Cancer (Cancer)
[2021, 127(5):729-738]

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Has the Outcome for Patients Who Undergo Resection of Primary Retroperitoneal Sarcoma Changed Over Time? A Study of Time Trends During the Past 15 years.

Dario Callegaro, Chandrajit P Raut, Deanna Ng, Dirk C Strauss, Charles Honoré, Eberhard Stoeckle, Sylvie Bonvalot, Rick L Haas, Nikolaos Vassos, Lorenzo Conti, Rebecca A Gladdy, Mark Fairweather, Winan van Houdt, Yvonne Schrage, Frits van Coevorden, Piotr Rutkowski, Rosalba Miceli, Alessandro Gronchi, Carol J Swallow,

<h4>Background</h4>This study aimed to investigate changes in treatment strategy and outcome for patients with primary retroperitoneal sarcoma (RPS) undergoing resection at referral centers during a recent period.<h4>Methods</h4>The study enrolled consecutive adult patients with primary non-metastatic RPS who underwent resection with curative intent between 2002 and 2017 at 10 referral centers. ... Read more >>

Ann Surg Oncol (Annals of surgical oncology)
[2021, 28(3):1700-1709]

Cited: 2 times

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Preoperative monocyte-to-lymphocyte ratio predicts recurrence in gastrointestinal stromal tumors.

Ferdinando Carlo Maria Cananzi, Eleonora Maddalena Minerva, Laura Samà, Laura Ruspi, Federico Sicoli, Lorenzo Conti, Uberto Fumagalli Romario, Vittorio Lorenzo Quagliuolo,

<h4>Background and objectives</h4>Several inflammation markers were found to have a prognostic value in cancer. We investigated the significance of preoperative white cell ratios in determining gastrointestinal stromal tumors (GISTs) outcome.<h4>Methods</h4>Clinicopathological features of patients who underwent surgery for GIST were reviewed. The following peripheral blood inflammation markers were calculated: neutrophil-lymphocyte ratio ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2019, 119(1):12-20]

Cited: 11 times

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Prevalence of Patent Foramen Ovale in Ischaemic Stroke in Italy: Results of SISIFO Study.

Domenico Consoli, Maurizio Paciaroni, Franco Galati, Marco Aguggia, Maurizio Melis, Giovanni Malferrari, Arturo Consoli, Simone Vidale, Domenico Bosco, Paolo Cerrato, Simona Sacco, Carlo Gandolfo, Paolo Bovi, Carlo Serrati, Massimo Del Sette, Anna Cavallini, Marina Diomedi, Paolo Postorino, Paolo Reboldi, Stefano Ricci, ,

<h4>Background</h4>Although several authors have studied the association between patent foramen ovale (PFO) and ischaemic stroke, the matter is still controversial; few have suggested an association between cryptogenetic stroke and PFO, while others have denied this association. The aim of this study was to evaluate PFO prevalence in the whole ischaemic ... Read more >>

Cerebrovasc Dis (Cerebrovascular diseases (Basel, Switzerland))
[2015, 39(3-4):162-169]

Cited: 13 times

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Duodenal diverted sleeve gastrectomy with ileal interposition does not cause biliary salt malabsorption.

Diego A Foschi, Andrea Rizzi, Igor Tubazio, Lorenzo Conti, Tarcisio Vago, Maurizio Bevilacqua, Alessandro Magni, Marina Del Puppo,

<h4>Background</h4>Duodenal diverted sleeve gastrectomy with ileal interposition (DDSG-II) is a bariatric-metabolic operation designed to treat type 2 diabetes mellitus (T2DM). It is restrictive (SG) but also acts on the small bowel with functional effects. The objective of the present study was to investigate whether or not it is also a ... Read more >>

Surg Obes Relat Dis (Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery)
[2015, 11(2):372-376]

Cited: 1 time

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Intraoperative forces and moments analysis on patient head clamp during awake brain surgery.

Danilo De Lorenzo, Elena De Momi, Lorenzo Conti, Emiliano Votta, Marco Riva, Enrica Fava, Lorenzo Bello, Giancarlo Ferrigno,

In brain surgery procedures, such as deep brain stimulation, drug-resistant epilepsy and tumour surgery, the patient is intentionally awakened to map functional neural bases via electrophysiological assessment. This assessment can involve patient's body movements; thus, increasing the mechanical load on the head-restraint systems used for keeping the skull still during ... Read more >>

Med Biol Eng Comput (Medical & biological engineering & computing)
[2013, 51(3):331-341]

Cited: 4 times

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