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Author Liyuan Han

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Integrated multisectoral non-communicable disease prevention and control in China: A review of agencies and policies.

Shiwei Liu, Zhuo Chen, Liyuan Han, Wenlan Dong, Hui Li, Jeffrey Koplan, Jing Wu, Xinhua Li,

J Glob Health (Journal of global health)
[2020, 10(2):020304]

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A comprehensive association analysis between homocysteine metabolic pathway gene methylation and ischemic stroke in a Chinese hypertensive population.

Bo Li, Yuying Li, Shan Xu, Hongen Chen, Shudong Dai, Xiaoling Peng, Li Wang, Yaping Liang, Cheng Li, Biwei Tang, Liqing Zhu, Tao Zhang, Chunfang Lv, Changyi Wang, Liyuan Han,

<h4>Background</h4>Ischemic stroke (IS) is a serious global health burden. In order to improve our understanding of the risk factors associated with IS, we investigated the combined effect of the methylation of five genes related to the metabolism of homocysteine on developing IS.<h4>Methods</h4>Quantitative methylation-specific PCR was used to measure the levels ... Read more >>

J Clin Lab Anal (Journal of clinical laboratory analysis)
[2020, :e23689]

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Fast food consumption among young adolescents aged 12-15 years in 54 low- and middle-income countries.

Lian Li, Ning Sun, Lina Zhang, Guodong Xu, Jingjing Liu, Jingcen Hu, Zhiying Zhang, Jianjun Lou, Hongxia Deng, Zhisen Shen, Liyuan Han,

<h4>Background</h4>Most countries worldwide, especially low- and middle-income countries (LMICs), are facing an increasing prevalence of fast-food consumption and multiple burdens of malnutrition among young adolescents.<h4>Objective</h4>To compare the prevalence of fast-food consumption among young adolescents in LMICs.<h4>Methods</h4>We used data from the most recent Global School-Based Student Health Survey (2009-2015), which had ... Read more >>

Glob Health Action (Global health action)
[2020, 13(1):1795438]

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High MTHFR promoter methylation levels in men confer protection against ischemic stroke.

Shan Xu, Qianping Shi, Bo Li, Liyuan Han, Guodong Xu, Xiaolin Peng, Hongen Chen, Shuhong Dai, Wancheng Ma, Changyi Wang, Jianping Ma,

The MTHFR gene encodes methylenetetrahydrofolate reductase required for the metabolism of homocysteine (Hcy) - a previously reported independent risk factor for ischemic stroke (IS). In this study, we first aimed to clarify the association between DNA methylation levels in the MTHFR promoter and the risk of IS, followed by the ... Read more >>

Bosn J Basic Med Sci (Bosnian journal of basic medical sciences)
[2020, 20(4):477-486]

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Ideal Cardiovascular Health Metrics and Incidence of Ischemic Stroke Among Hypertensive Patients: A Prospective Cohort Study.

Yuchen Ying, Shaoyi Lin, Fanqian Kong, Yuying Li, Shujun Xu, Xiaofeng Liang, Changyi Wang, Liyuan Han,

<b>Background:</b> This study aimed to assess the relationship between ideal cardiovascular health (CVH) metrics and incident ischemic stroke (IS) in hypertensive patients, especially those with hyperhomocysteinemia (HHcy). <b>Methods:</b> A prospective cohort study enrolled 5,488 hypertensive patients in Nanshan District of Shenzhen City in southern China from September 2011 to December ... Read more >>

Front Cardiovasc Med (Frontiers in cardiovascular medicine)
[2020, 7:590809]

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Alterations of 5-hydroxymethylcytosines in circulating cell-free DNA reflect retinopathy in type 2 diabetes.

Liyuan Han, Chang Chen, Xingyu Lu, Yanqun Song, Zhou Zhang, Chang Zeng, Rudyard Chiu, Li Li, Miao Xu, Chuan He, Wei Zhang, Shiwei Duan,

Diabetic retinopathy (DR) is a common microvascular complication that may cause severe visual impairment and blindness in patients with type 2 diabetes mellitus (T2DM). Early detection of DR will expand the range of potential treatment options and enable better control of disease progression. Epigenetic dysregulation has been implicated in the ... Read more >>

Genomics (Genomics)
[2021, 113(1 Pt 1):79-87]

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Hygiene practices among young adolescents aged 12-15 years in low- and middle-income countries: a population-based study.

Liyuan Han, Xuping Gao, Minqi Liao, Xiaoxuan Yu, Ruijie Zhang, Shiwei Liu, Fangfang Zeng,

<h4>Background</h4>Poor personal hygiene increases disease risk, however, the prevalence of hygiene practices among adolescents is poorly described in low- and middle-income countries (LMICs). We aimed to assess the hygiene practices among young adolescents in LMICs using data from the Global School-based Student Health Surveys (GSHS).<h4>Methods</h4>This population-based study analysed the GSHS ... Read more >>

J Glob Health (Journal of global health)
[2020, 10(2):020436]

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The prevalence of suicidal behaviors and their mental risk factors among young adolescents in 46 low- and middle-income countries.

Lian Li, Dingyun You, Tiecheng Ruan, Shujun Xu, Duo Mi, Ting Cai, Liyuan Han,

<h4>Background</h4>To describe the prevalence of suicidal behaviors (ideation, planning, and attempt) and their associated factors in young adolescents in low- and middle-income countries (LMICs).<h4>Methods</h4>We used the latest data from the Global School-Based Health Survey (GSHS) for adolescents aged 12-15 years during 2009-2015. The weighted prevalence and 95% confidential intervals (CIs) ... Read more >>

J Affect Disord (Journal of affective disorders)
[2020, :]

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Multiple biomarkers covering several pathways for the prediction of depression after ischemic stroke.

Bizhong Che, Zhengbao Zhu, Xiaoqing Bu, Jieyun Yin, Liyuan Han, Tan Xu, Zhong Ju, Jiale Liu, Jintao Zhang, Jing Chen, Jiang He, Yonghong Zhang, Chongke Zhong,

<h4>Background</h4>To assess the potential incremental utility of multiple biomarkers reflecting several pathological pathways for the risk prediction of depression after stroke.<h4>Methods</h4>We used data from the China Antihypertensive Trial in Acute Ischemic Stroke, and a panel of 13 circulating biomarkers were measured. The study outcome was depression (24-item Hamilton Depression Rating ... Read more >>

J Affect Disord (Journal of affective disorders)
[2021, 280(Pt A):442-449]

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Ink Engineering of Inkjet Printing Perovskite.

Zehua Li, Pengwei Li, Gangshu Chen, Yajie Cheng, Xiaodong Pi, Xuegong Yu, Deren Yang, Liyuan Han, Yiqiang Zhang, Yanlin Song,

Inkjet printing method is one of the most effective ways for fabricating large-area perovskite solar cells (PSCs). However, because ink crystallizes rapidly during printing, the printed perovskite film is discontinuous with increasing defects. It severely restricts the application of the inkjet printing technology to the fabrication of perovskite photovoltaic devices. ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2020, 12(35):39082-39091]

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Influence of lipoprotein-associated phospholipase A2 mass on prognosis value of baseline platelet count for clinical outcomes after acute ischemic stroke.

Suwen Shen, Chongke Zhong, Aili Wang, Liyuan Han, Zhengbao Zhu, Yanbo Peng, Hao Peng, Daoxia Guo, Xiaowei Zheng, Tan Xu, Jing Chen, Zhong Ju, Deqin Geng, Yonghong Zhang, Jiang He,

<h4>Background and aims</h4>We aimed to examine the association between baseline platelet count (PLT) and prognosis of acute ischemic stroke according to lipoprotein-associated phospholipase A<sub>2</sub> (Lp-PLA<sub>2</sub>) mass.<h4>Methods</h4>A total of 3254 patients with acute ischemic stroke were included in this analysis. The primary outcome was a combination of major disability and all-cause ... Read more >>

Atherosclerosis (Atherosclerosis)
[2020, 306:50-56]

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Skipping breakfast and physical fitness among school-aged adolescents.

Jingcen Hu, Zhifei Li, Sixuan Li, Hui Li, Sijia Wang, Shuyu Wang, Lei Xu, Delun Yang, Tiecheng Ruan, Hang Li, Shuo Han, Qinghai Gong, Liyuan Han,

<h4>Objectives</h4>This study explored the relationship between skipping breakfast and physical fitness in a group of school-aged adolescents in China.<h4>Methods</h4>This cross-sectional study from the Chinese National Surveillance on Students' Constitution and Health (CNSSCH) survey in Ningbo, China, used a standardized questionnaire to assess the frequency of breakfast consumption. Physical fitness was ... Read more >>

Clinics (Sao Paulo) (Clinics (Sao Paulo, Brazil))
[2020, 75:e1599]

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Efficient and stable tin perovskite solar cells enabled by amorphous-polycrystalline structure.

Xiao Liu, Yanbo Wang, Tianhao Wu, Xin He, Xiangyue Meng, Julien Barbaud, Han Chen, Hiroshi Segawa, Xudong Yang, Liyuan Han,

Tin perovskite solar cells (TPSCs) have triggered intensive research as a promising candidate for lead-free perovskite solar cells. However, it is still challenging to obtain efficient and stable TPSCs because of the low defects formation energy and the oxidation of bivalent tin; Here, we report a TPSC with a stable ... Read more >>

Nat Commun (Nature communications)
[2020, 11(1):2678]

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The Effectiveness of bFGF in the Treatment of Tympanic Membrane Perforations: A Systematic Review and Meta-Analysis.

Juntao Huang, Bing Mei Teh, Robert Henry Eikelboom, Liyuan Han, Guodong Xu, Xu Yao, Yi Hu, Minghao Zheng, Yi Shen,

OBJECTIVE:To investigate the effectiveness of basic fibroblast growth factor (bFGF) versus placebo or no intervention in the treatment of tympanic membrane (TM) perforations from randomized controlled trials (RCTs), prospective and retrospective studies. DATA SOURCES:PubMed, EMBASE, and Cochrane databases were screened from their inceptions to June 2019. STUDY SELECTION:Inclusion criteria: 1) ... Read more >>

Otol Neurotol (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2020, 41(6):782-790]

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Physical behaviors of 12-15 year-old adolescents in 54 low- and middle-income countries: Results from the Global School-based Student Health Survey.

Guodong Xu, Ning Sun, Lian Li, Wanfu Qi, Changwei Li, Maigeng Zhou, Zhu Chen, Liyuan Han,

Background:To describe and compare the separate and combined prevalence of physical activity, active transportation, physical education, and sedentary behavior among adolescents 12-15 year-olds in low- and middle-income countries (LMICs). Methods:We used the latest data from the Global School-based Student Health Survey (GSHS), which collect data on the physical behaviors of ... Read more >>

J Glob Health (Journal of global health)
[2020, 10(1):010423]

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NiCo2O4 nanosheets sheathed [email protected] core-shell nanowires for high-performance flexible hybrid supercapacitors.

Xuemin Yin, Hejun Li, Liyuan Han, Ruimei Yuan, Jinhua Lu,

Electrode materials with hierarchical self-supporting core-shell structures, with the metric of structural advantages and synergetic effect for different components, have been widely applied in supercapacitor. Besides, interface designing would improve the bonding of different components and further enhance the stability of electrochemical performance. In this work, by the introduction of ... Read more >>

J Colloid Interface Sci (Journal of colloid and interface science)
[2020, 577:481-493]

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Multidimensional social and cultural norms influencing HPV vaccine hesitancy in Asia.

Li Ping Wong, Pooi-Fong Wong, Megat Mohamad Amirul Amzar Megat Hashim, Liyuan Han, Yulan Lin, Zhijian Hu, Qinjian Zhao, Gregory D Zimet,

HPV vaccine hesitancy in Asia is unique compared to Western countries due to multidimensional social-cultural norms that influence beliefs regarding vaccination. Reviews on HPV vaccine hesitancy in Asia lack of in-depth discussion regarding the traditional and social-cultural norms dimensions. This paper puts forward opinions in which culture, normative beliefs, and ... Read more >>

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2020, 16(7):1611-1622]

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Streptomyces montanus sp. nov., a novel actinomycete isolated from soil.

Hao Jiang, Liyuan Han, Jingjing Li, Mingying Yu, Junwei Zhao, Xiaowei Guo, Wensheng Xiang, Xiangjing Wang,

A novel actinomycete, designated strain NEAU-C151T, was isolated from soil collected from Mount Song and characterized using a polyphasic approach. Analysis of the 16S rRNA gene sequence indicated that strain NEAU-C151T belongs to the genus Streptomyces and exhibited 97.5, 97.4 and 97.4 % similarities to Streptomyces lincolnensis NRRL 2936T, Streptomyces coacervatus ... Read more >>

Int J Syst Evol Microbiol (International journal of systematic and evolutionary microbiology)
[2020, 70(5):3226-3233]

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Sleep and suicidality in school-aged adolescents: A prospective study with 2-year follow-up.

Qinghai Gong, Sixuan Li, Sijia Wang, Hui Li, Liyuan Han,

Current evidence about the association between sleep and suicide are conflicting. This study aimed to investigate the association between sleep duration and quality with suicidal behaviors in a group of school-aged adolescents in China. The baseline survey was conducted among Chinese adolescents aged 12-13 years in October 2016. All participants ... Read more >>

Psychiatry Res (Psychiatry research)
[2020, 287:112918]

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Highly Reproducible and Efficient FASnI3 Perovskite Solar Cells Fabricated with Volatilizable Reducing Solvent.

Xiangyue Meng, Tianhao Wu, Xiao Liu, Xin He, Takeshi Noda, Yanbo Wang, Hiroshi Segawa, Liyuan Han,

Lead-free tin halide perovskite solar cells (PSCs) have attracted great attention because of their low toxicity, ideal band gap, and high carrier mobilities. However, the efficiency and reproducibility of tin halide PSCs has been limited because of the facile oxidation of Sn<sup>2+</sup> to Sn<sup>4+</sup>. Herein, liquid formic acid (LFA) was ... Read more >>

J Phys Chem Lett (The journal of physical chemistry letters)
[2020, 11(8):2965-2971]

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Herbidospora galbida sp. nov., a novel actinobacterium isolated from soil.

Liyuan Han, Mingying Yu, Junwei Zhao, Hao Jiang, Xiaowei Guo, Guijin Shen, Yue Shen, Xiangjing Wang, Wensheng Xiang,

A novel actinobacterium, designated strain NEAU-GS14T, was isolated from soil of a flower bed in a residential area in Sanya, Hainan Province, China, and characterized using a polyphasic approach. Morphological and chemotaxonomic characteristics of the strain coincided with members of the genus Herbidospora. The 16S rRNA gene sequence analysis showed ... Read more >>

Int J Syst Evol Microbiol (International journal of systematic and evolutionary microbiology)
[2020, 70(2):1364-1371]

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The role of institutional trust in preventive and treatment-seeking behaviors during the 2019 novel coronavirus (2019-nCoV) outbreak among residents in Hubei, China

Liping Wong, Qunhong Wu, Xi Chen, Zhuo Chen, Haridah Alias, Mingwang Shen, Jingcen Hu, Shiwei Duan, Jinjie Zhang, Liyuan Han,

<h4>Background</h4> Since December 2019, pneumonia associated with the 2019 novel coronavirus (2019-nCoV) has emerged in Wuhan, China. The exponential increase of the confirmed number of cases of 2019n-CoV is of great concern to the global community. The fears and panic among residents in the epicenters have prompted diverse responses, which ... Read more >>

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The impact of traffic isolation in Wuhan on the spread of 2019-nCov

Gehui Jin, Jiayu Yu, Liyuan Han, Shiwei Duan,

The 2019-nCoV outbreak occurred near the Chinese Spring Festival transport period in Wuhan. As an important transportation center, the migration of Wuhan accelerated the spread of 2019-nCoV across mainland China. Based on the cumulative Baidu migration index (CBMI), we first analyzed the proportion of Wuhan’s migrant population to other cities. ... Read more >>

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Human Papillomavirus (HPV) Vaccine Uptake and the Willingness to Receive the HPV Vaccination among Female College Students in China: A Multicenter Study.

Dingyun You, Liyuan Han, Lian Li, Jingcen Hu, Gregory D Zimet, Haridah Alias, Mahmoud Danaee, Le Cai, Fangfang Zeng, Li Ping Wong,

BACKGROUND:This study aimed to determine human papillomavirus (HPV) vaccine uptake and willingness to receive HPV vaccination among female college students, in China, and its associated factors. METHODS:An online cross-sectional survey of female college students across the eastern, central, and western regions of China was undertaken between April and September 2019. ... Read more >>

Vaccines (Basel) (Vaccines)
[2020, 8(1):]

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CpG single nucleotide polymorphisms of the insulin signaling pathway associated with the risk of prediabetic status/type 2 diabetes in Chinese population

Linlin Tang, Changyi Wang, Liyuan Han, Jianping Ma, Jia Cheng, Shiwei Duan,

<h4>Aims: </h4> Cytosine-phosphate-guanine single nucleotide polymorphisms (CpG SNPs) have been identified as new markers in human diseases. We aimed to evaluate the contribution of 29 CpG SNPs in the insulin signaling pathways to the risk of prediabetes and type 2 diabetes (T2D) in Han Chinese. Materials and methods: We recruited ... Read more >>

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