Full Text Journal Articles by
Author Lisa Story

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FIGO good practice recommendations on cervical cerclage for prevention of preterm birth.

Andrew Shennan, Lisa Story, Bo Jacobsson, William A Grobman, ,

Cervical cerclage is an intervention which when given to the right women can prevent preterm birth and second-trimester fetal losses. A history-indicated cerclage should be offered to women who have had three or more preterm deliveries and/or mid-trimester losses. An ultrasound-indicated cerclage should be offered to women with a cervical ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):19-22]

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Assessment of the fetal thymus gland: Comparing MRI-acquired thymus volumes with 2D ultrasound measurements.

Rebecca Myers, Jana Hutter, Jacqueline Matthew, Tong Zhang, Alena Uus, David Lloyd, Alexia Egloff, Maria Deprez, Surabhi Nanda, Mary Rutherford, Lisa Story,

<h4>Objectives</h4>The fetal thymus gland has been shown to involute in response to intrauterine infection, and therefore could be used as a non-invasive marker of fetal compartment infection. The objective of this study was to evaluate how accurately 2D ultrasound-derived measurements of the fetal thymus reflect the 3D volume of the ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2021, 264:1-7]

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Maternal and fetal incidental findings on antenatal magnetic resonance imaging.

Lisa Story, Caroline L Knight, Alison Ho, Sophie Arulkumaran, Jacqueline Matthews, Holly Lovell, Laura McCabe, Megan Byrne, Alexia Egloff, Audrey E T Jacques, Jim Carmichael, Jo Hajnal, Andrew Shennan, Mary Rutherford,

<h4>Background</h4>Magnetic resonance imaging (MRI) examinations are increasingly used in antenatal clinical practice. Incidental findings are a recognized association with imaging and although in some circumstances their identification can alter management, they are often associated with increased anxiety, for both patient and clinician, as well as increased health care costs.<h4>Objective</h4>This study ... Read more >>

Pediatr Radiol (Pediatric radiology)
[2021, 51(10):1839-1847]

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Brain volumetry in fetuses that deliver very preterm: An MRI pilot study.

Lisa Story, Alice Davidson, Prachi Patkee, Bobbi Fleiss, Vanessa Kyriakopoulou, Kathleen Colford, Srividhya Sankaran, Paul Seed, Alice Jones, Jana Hutter, Andrew Shennan, Mary Rutherford,

<h4>Background</h4>Infants born preterm are at increased risk of neurological complications resulting in significant morbidity and mortality. The exact mechanism and the impact of antenatal factors has not been fully elucidated, although antenatal infection/inflammation has been implicated in both the aetiology of preterm birth and subsequent neurological sequelae. It is therefore ... Read more >>

Neuroimage Clin (NeuroImage. Clinical)
[2021, 30:102650]

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Placental magnetic resonance imaging in chronic hypertension: A case-control study.

Alison Ho, Jana Hutter, Paddy Slator, Laurence Jackson, Paul T Seed, Laura Mccabe, Mudher Al-Adnani, Andreas Marnerides, Simi George, Lisa Story, Joseph V Hajnal, Mary Rutherford, Lucy C Chappell,

<h4>Introduction</h4>We aimed to explore the use of magnetic resonance imaging (MRI) in vivo as a tool to elucidate the placental phenotype in women with chronic hypertension.<h4>Methods</h4>In case-control study, women with chronic hypertension and those with uncomplicated pregnancies were imaged using either a 3T Achieva or 1.5T Ingenia scanner. T2-weighted images, ... Read more >>

Placenta (Placenta)
[2021, 104:138-145]

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CRAFT (Cerclage after full dilatation caesarean section): protocol of a mixed methods study investigating the role of previous in-labour caesarean section in preterm birth risk.

Naomi Carlisle, Agnieszka Glazewska-Hallin, Lisa Story, Jenny Carter, Paul T Seed, Natalie Suff, Lucie Giblin, Jana Hutter, Raffaele Napolitano, Mary Rutherford, Daniel C Alexander, Nigel Simpson, Amrita Banerjee, Anna L David, Andrew H Shennan,

<h4>Background</h4>Full dilatation caesarean sections are associated with recurrent early spontaneous preterm birth and late miscarriage. The risk following first stage caesarean sections, are less well defined, but appears to be increased in late-first stage of labour. The mechanism for this increased risk of late miscarriage and early spontaneous preterm birth ... Read more >>

BMC Pregnancy Childbirth (BMC pregnancy and childbirth)
[2020, 20(1):698]

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Antenatal thymus volumes in fetuses that delivered <32 weeks' gestation: An MRI pilot study.

Lisa Story, Tong Zhang, Alena Uus, Jana Hutter, Alexia Egloff, Deena Gibbons, Alison Ho, Mudher Al-Adnani, Caroline L Knight, Iakovos Theodoulou, Maria Deprez, Paul T Seed, Rachel M Tribe, Andrew H Shennan, Mary Rutherford,

<h4>Introduction</h4>Infection and inflammation have been implicated in the etiology and subsequent morbidity associated with preterm birth. At present, there are no tests to assess for fetal compartment infection. The thymus, a gland integral in the fetal immune system, has been shown to involute in animal models of antenatal infection, but ... Read more >>

Acta Obstet Gynecol Scand (Acta obstetricia et gynecologica Scandinavica)
[2021, 100(6):1040-1050]

Cited: 1 time

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Efficacy of transvaginal cervical cerclage in women at risk of preterm birth following previous emergency cesarean section.

Maria M Hickland, Lisa Story, Agnieszka Glazewska-Hallin, Natalie Suff, Matthew Cauldwell, Helena A Watson, Jenny Carter, Kate E Duhig, Andrew H Shennan,

<h4>Introduction</h4>Emergency cesarean sections (EMCS) are associated with subsequent preterm birth, particularly at full dilation (FDCS), which is a cause of both second trimester miscarriages and early, recurrent spontaneous preterm birth (sPTB). The optimal management for these women in subsequent pregnancies is currently unknown. This study aims to assess efficacy of ... Read more >>

Acta Obstet Gynecol Scand (Acta obstetricia et gynecologica Scandinavica)
[2020, 99(11):1486-1491]

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T2* Placental Magnetic Resonance Imaging in Preterm Preeclampsia: An Observational Cohort Study.

Alison E P Ho, Jana Hutter, Laurence H Jackson, Paul T Seed, Laura Mccabe, Mudher Al-Adnani, Andreas Marnerides, Simi George, Lisa Story, Joseph V Hajnal, Mary A Rutherford, Lucy C Chappell,

Placental dysfunction underlies the cause of pregnancies complicated by preeclampsia. The use of placental magnetic resonance imaging to provide an insight into the pathophysiology of preeclampsia and thus assess its potential use to inform prognosis and clinical management was explored. In this prospective observational cohort study, 14 women with preterm ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2020, 75(6):1523-1531]

Cited: 4 times

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Foetal lung volumes in pregnant women who deliver very preterm: a pilot study.

Lisa Story, Tong Zhang, Johannes K Steinweg, Jana Hutter, Jacqueline Matthew, Theodore Dassios, Paul T Seed, Dharmintra Pasupathy, Joanna Allsop, Joseph V Hajnal, Anne Greenough, Andrew H Shennan, Mary Rutherford,

<h4>Background</h4>Infants born preterm are at increased risk of pulmonary morbidity. The contribution of antenatal factors to impairments in lung structure/function has not been fully elucidated. This study aimed to compare standardized lung volumes from foetuses that were delivered <32 weeks' gestation with foetuses that were delivered >37 weeks.<h4>Methods</h4>Fourteen women who ... Read more >>

Pediatr Res (Pediatric research)
[2020, 87(6):1066-1071]

Cited: 0 times

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T2* relaxometry to characterize normal placental development over gestation in-vivo at 3T

Jana Hutter, Laurence Jackson, Alison Ho, Maximilian Pietsch, Lisa Story, Lucy Chappell, Joseph Hajnal, Mary Rutherford,

Background: T2* relaxometry has been identified as a non-invasive way to study the placenta in-vivo with good potential to identify placental insufficiency. Typical interpretation links T2* values to oxygen concentrations. This study aimed to comprehensively assess T2* maps as a marker of placental oxygenation in-vivo . Methods : A multi-echo ... Read more >>

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Reducing the impact of preterm birth: Preterm birth commissioning in the United Kingdom.

Lisa Story, Nigel A B Simpson, Anna L David, Zarko Alfirevic Z, Phillip R Bennett, Matthew Jolly, Andrew H Shennan, ,

Reducing preterm birth is a priority for Maternity and Children's services. In the recent UK Department of Health publication 'Safer Maternity Care' the Secretary of State for Health aimed to achieve the national maternity safety ambition by pledging to reduce the rate of preterm birth from 8% to 6%. It ... Read more >>

Eur J Obstet Gynecol Reprod Biol X (European journal of obstetrics & gynecology and reproductive biology: X)
[2019, 3:100018]

Cited: 2 times

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The prediction of preterm delivery: What is new?

Natalie Suff, Lisa Story, Andrew Shennan,

Preterm birth, defined as birth occurring prior to 37 weeks gestation, is a serious obstetric problem accounting for 11% of pregnancies worldwide. It is associated with significant neonatal morbidity and mortality. Predictive tests for preterm birth are incredibly important, given the huge personal, economic, and health impacts of preterm birth. ... Read more >>

Semin Fetal Neonatal Med (Seminars in fetal & neonatal medicine)
[2019, 24(1):27-32]

Cited: 14 times

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Multi-modal functional MRI to explore placental function over gestation.

Jana Hutter, Paddy J Slator, Laurence Jackson, Ana Dos Santos Gomes, Alison Ho, Lisa Story, Jonathan O'Muircheartaigh, Rui P A G Teixeira, Lucy C Chappell, Daniel C Alexander, Mary A Rutherford, Joseph V Hajnal,

<h4>Purpose</h4>To investigate, visualize and quantify the physiology of the human placenta in several dimensions - functional, temporal over gestation, and spatial over the whole organ.<h4>Methods</h4>Bespoke MRI techniques, combining a rich diffusion protocol, anatomical data and T2* mapping together with a multi-modal pipeline including motion correction and extracted quantitative features were ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2019, 81(2):1191-1204]

Cited: 10 times

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Aspirin versus placebo in pregnancies at high risk for preterm pre-eclampsia.

Lisa Story, Catherine Nelson-Piercy,

A recent multicentre placebo-controlled trial by Rolnick et al. has indicated that taking 150 mg aspirin daily in women at high risk of pre-eclampsia reduced the incidence of the disease from 4.3% to 1.5% in comparison with placebo. Although the findings of this study are important, a high proportion of women ... Read more >>

Obstet Med (Obstetric medicine)
[2018, 11(2):90-91]

Cited: 0 times

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Preterm pre-eclampsia: What every neonatologist should know.

Lisa Story, Lucy C Chappell,

Although pre-eclampsia affects 5-10% of pregnancies globally and is responsible for substantial maternal and perinatal morbidity and mortality, currently there is no cure other than delivery of the baby. Predictive screening tests based on clinical risk factors, with or without the addition of biomarkers and imaging, have been developed, but ... Read more >>

Early Hum Dev (Early human development)
[2017, 114:26-30]

Cited: 2 times

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Placenta Maps: In Utero Placental Health Assessment of the Human Fetus.

Haichao Miao, Gabriel Mistelbauer, Alexey Karimov, Amir Alansary, Alice Davidson, David F A Lloyd, Mellisa Damodaram, Lisa Story, Jana Hutter, Joseph V Hajnal, Mary Rutherford, Bernhard Preim, Bernhard Kainz, M Eduard Groller,

The human placenta is essential for the supply of the fetus. To monitor the fetal development, imaging data is acquired using (US). Although it is currently the gold-standard in fetal imaging, it might not capture certain abnormalities of the placenta. (MRI) is a safe alternative for the in utero examination ... Read more >>

IEEE Trans Vis Comput Graph (IEEE transactions on visualization and computer graphics)
[2017, 23(6):1612-1623]

Cited: 3 times

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An assessment of mode of delivery in history indicated versus ultrasound indicated vaginally placed cervical cerclage.

Lisa Story, Andrew Shennan,

<h4>Objective</h4>Treatment modalities to reduce the incidence of preterm birth are currently limited. Cerclage, is a common and established intervention in most obstetrics units worldwide, however, many questions regarding its efficacy, with respect to pregnancy outcomes remain unanswered. This study aims to investigate whether an antenatal placed cerclage affects the subsequent ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2017, 210:123-125]

Cited: 0 times

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Survival of pregnancies with small for gestational age detected before 24 weeks gestation.

Lisa Story, Srividhya Sankaran, Edward Mullins, Su Tan, Glynn Russell, Sailesh Kumar, Pippa Kyle,

<h4>Objective</h4>Counselling women where severe growth abnormalities are detected early in the pregnancy is often difficult due to a paucity of outcome data of this specific subset of early onset disease. This study therefore aimed to assess the outcome of pregnancies where an estimated fetal weight less than the third centile ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2015, 188:100-103]

Cited: 8 times

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Influence of birthweight on perinatal outcome in fetuses with antenatal diagnosis of congenital heart disease.

Lisa Story, Dharmintra Pasupathy, Srividhya Sankaran, Gurleen Sharland, Pippa Kyle,

<h4>Aim</h4>The incidence of congenital heart disease (CHD) accounts for the largest proportion of infant mortality attributable to birth defects. Associations have previously been reported between CHD and low birthweight. Low birthweight is independently associated with adverse outcome and has characteristically been calculated using population-based charts. This aim of this study ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2015, 41(6):896-903]

Cited: 5 times

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Myo-inositol metabolism in appropriately grown and growth-restricted fetuses: a proton magnetic resonance spectroscopy study.

Lisa Story, Mellisa S Damodaram, Veena Supramaniam, Joanna M Allsop, Amy Mcguinness, Abhilasha Patel, Marzena Wylezinska, Sailesh Kumar, Mary A Rutherford,

<h4>Objective</h4>Myo-inositol (Myo-ins) is a marker of neuroglial cells, being present in the astrocytes of brain tissue, but also functions as an osmolyte. Numbers of astrocytes are known to increase following injury to the brain. Growth-restricted fetuses are at increased risk of later neurodevelopmental impairments even in the absence of overt ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2013, 170(1):77-81]

Cited: 7 times

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Foetal volumetry using magnetic resonance imaging in intrauterine growth restriction.

Mellisa S Damodaram, Lisa Story, Elisanda Eixarch, Prachi Patkee, Abhilasha Patel, Sailesh Kumar, Mary Rutherford,

<h4>Objectives</h4>We used magnetic resonance imaging (MRI) to perform volumetry of foetuses with and without growth restriction, and identify deviations in organ growth.<h4>Study design</h4>20 growth restricted and 19 normal foetuses were scanned once during pregnancy at gestational age 20.53-36.57 weeks. MRI scans were performed on a 1.5T system using ssFSE sequences. ... Read more >>

Early Hum Dev (Early human development)
[2012, 88 Suppl 1:S35-40]

Cited: 15 times

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Early adverse perinatal complications in preterm growth-restricted fetuses.

Mellisa Damodaram, Lisa Story, Elena Kulinskaya, Mary Rutherford, Sailesh Kumar,

<h4>Introduction</h4>Growth-restricted fetuses are at increased risk of adverse perinatal outcome when compared to their normally grown counterparts. The additional risks associated with growth restriction in preterm fetuses are not well quantified, and this meta-analysis serves to address this uncertainty.<h4>Materials and methods</h4>This is a meta-analysis and meta-regression of all relevant studies ... Read more >>

Aust N Z J Obstet Gynaecol (The Australian & New Zealand journal of obstetrics & gynaecology)
[2011, 51(3):204-209]

Cited: 35 times

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Brain metabolism in fetal intrauterine growth restriction: a proton magnetic resonance spectroscopy study.

Lisa Story, Mellisa S Damodaram, Joanna M Allsop, Amy McGuinness, Abhilasha Patel, Marzena Wylezinska, Henrik Hagberg, Sailesh Kumar, Mary A Rutherford,

<h4>Objective</h4>The purpose of this study was to investigate alterations in brain metabolism in fetuses with intrauterine growth restriction (IUGR) and evidence of cerebral redistribution of blood flow.<h4>Study design</h4>Biometry and Doppler assessment of blood flow was assessed with ultrasound in 28 fetuses with IUGR and cerebral redistribution and in 41 appropriately ... Read more >>

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2011, 205(5):483.e1-8]

Cited: 26 times

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Proton magnetic resonance spectroscopy in the fetus.

Lisa Story, Mellisa S Damodaram, Joanna M Allsop, Amy McGuinness, Marzena Wylezinska, Sailesh Kumar, Mary A Rutherford,

Magnetic Resonance Imaging (MRI) has become an established technique in fetal medicine, providing complementary information to ultrasound in studies of the brain. MRI can provide detailed structural information irrespective of the position of the fetal head or maternal habitus. Proton Magnetic Resonance Spectroscopy ((1)HMRS) is based on the same physical ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2011, 158(1):3-8]

Cited: 14 times

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