Full Text Journal Articles by
Author Lindsay M Squeglia

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Intention to Quit Vaping Among United States Adolescents.

Tracy T Smith, Georges J Nahhas, Matthew J Carpenter, Lindsay M Squeglia, Vanessa A Diaz, Adam M Leventhal, Jennifer Dahne,

JAMA Pediatr (JAMA pediatrics)
[2021, 175(1):97-99]

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Racial Disparities in Elementary School Disciplinary Actions: Findings From the ABCD Study.

Matthew C Fadus, Emilio A Valadez, Brittany E Bryant, Alexis M Garcia, Brian Neelon, Rachel L Tomko, Lindsay M Squeglia,

<h4>Objective</h4>Detentions and suspensions are common practices of school discipline despite evidence that they are largely ineffective and disproportionately affect children from racial and ethnic minority backgrounds, particularly Black children, and children of lower socioeconomic status. However, few studies have examined suspension and detention rates among race, ethnicity, and family structure ... Read more >>

J Am Acad Child Adolesc Psychiatry (Journal of the American Academy of Child and Adolescent Psychiatry)
[2020, :]

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Screen media activity does not displace other recreational activities among 9-10 year-old youth: a cross-sectional ABCD study®.

Briana Lees, Lindsay M Squeglia, Florence J Breslin, Wesley K Thompson, Susan F Tapert, Martin P Paulus,

<h4>Background</h4>Screen media is among the most common recreational activities engaged in by children. The displacement hypothesis predicts that increased time spent on screen media activity (SMA) may be at the expense of engagement with other recreational activities, such as sport, music, and art. This study examined associations between non-educational SMA ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):1783]

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Problems experienced by children from families with histories of substance misuse: An ABCD study®.

Briana Lees, Lexine A Stapinski, Maree Teesson, Lindsay M Squeglia, Joanna Jacobus, Louise Mewton,

<h4>Background</h4>There are significant knowledge gaps of the vulnerabilities faced by youth from families with histories of alcohol or substance misuse. This study aimed to provide a comprehensive assessment of problems experienced by substance-naive children with positive family histories of substance misuse (FHP).<h4>Methods</h4>Baseline data from up to 11,873 children (52.1 % ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2021, 218:108403]

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Alcohol and the developing adolescent brain.

Lindsay M Squeglia,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2020, 19(3):393-394]

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Association of Prenatal Alcohol Exposure With Psychological, Behavioral, and Neurodevelopmental Outcomes in Children From the Adolescent Brain Cognitive Development Study.

Briana Lees, Louise Mewton, Joanna Jacobus, Emilio A Valadez, Lexine A Stapinski, Maree Teesson, Susan F Tapert, Lindsay M Squeglia,

<h4>Objective</h4>Data on the neurodevelopmental and associated behavioral effects of light to moderate in utero alcohol exposure are limited. This retrospective investigation tested for associations between reported maternal prenatal alcohol use and psychological, behavioral, and neurodevelopmental outcomes in substance-naive youths.<h4>Methods</h4>Participants were 9,719 youths (ages 9.0 to 10.9 years) from the Adolescent ... Read more >>

Am J Psychiatry (The American journal of psychiatry)
[2020, 177(11):1060-1072]

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Altered Neurocognitive Functional Connectivity and Activation Patterns Underlie Psychopathology in Preadolescence.

Briana Lees, Lindsay M Squeglia, Lisa M McTeague, Miriam K Forbes, Robert F Krueger, Matthew Sunderland, Andrew J Baillie, Forrest Koch, Maree Teesson, Louise Mewton,

<h4>Background</h4>Neurocognitive deficits are common among youth with mental disorders, and patterns of aberrant brain function generally cross diagnostic boundaries. This study investigated associations between functional neurocircuitry and broad transdiagnostic psychopathology dimensions in the critical preadolescent period when psychopathology is emerging.<h4>Methods</h4>Participants were 9- to 10-year-olds from the Adolescent Brain Cognitive Development ... Read more >>

Biol Psychiatry Cogn Neurosci Neuroimaging (Biological psychiatry. Cognitive neuroscience and neuroimaging)
[2020, :]

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Piloting of the Just Say Know prevention program: a psychoeducational approach to translating the neuroscience of addiction to youth.

Lindsay R Meredith, Anna M Maralit, Suzanne E Thomas, Sylvia L Rivers, Claudia A Salazar, Raymond F Anton, Rachel L Tomko, Lindsay M Squeglia,

<h4>Background</h4>Substance use during adolescence can have a number of negative consequences and interfere with normal brain development. Given limited time and resources, brief group- and school-based prevention programs are an efficient strategy for educating youth about the effects of substance use on health outcomes.<h4>Objectives</h4>To determine if a science-based, interactive substance ... Read more >>

Am J Drug Alcohol Abuse (The American journal of drug and alcohol abuse)
[2020, :1-10]

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Association of prenatal alcohol exposure with preadolescent alcohol sipping in the ABCD study®.

Briana Lees, Louise Mewton, Lexine A Stapinski, Maree Teesson, Lindsay M Squeglia,

<h4>Background</h4>Early alcohol use initiation is one of the strongest predictors of alcohol use disorders. Identifying modifiable risk factors for problematic alcohol use can guide prevention initiatives. Globally, approximately 10% of women consume alcohol during pregnancy, however the impact of prenatal alcohol exposure (PAE) on offspring alcohol use patterns has been ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2020, 214:108187]

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Cannabis and Alcohol Co-Use in a Smoking Cessation Pharmacotherapy Trial for Adolescents and Emerging Adults.

Erin A McClure, Nathaniel L Baker, Caitlyn O Hood, Rachel L Tomko, Lindsay M Squeglia, Julianne C Flanagan, Matthew J Carpenter, Kevin M Gray,

INTRODUCTION:The co-use of cannabis and alcohol among tobacco-using youth is common. Alcohol co-use is associated with worse tobacco cessation outcomes, but results are mixed regarding the impact of cannabis on tobacco outcomes and if co-use leads to increased use of non-treated substances. This secondary analysis from a youth smoking cessation ... Read more >>

Nicotine Tob Res (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco)
[2020, 22(8):1374-1382]

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Parental Family History of Alcohol Use Disorder and Neural Correlates of Response Inhibition in Children From the Adolescent Brain Cognitive Development (ABCD) Study.

Briana Lees, Laika Aguinaldo, Lindsay M Squeglia, Maria Alejandra Infante, Natasha E Wade, Margie Hernandez Mejia, Joanna Jacobus,

<h4>Background</h4>Youth whose parents have alcohol use disorder (AUD) are at higher risk for earlier initiation and greater magnitude of alcohol use, and have a higher likelihood of developing an AUD than their peers without parental history of AUD. This increased risk may be partly attributable to altered development of inhibitory ... Read more >>

Alcohol Clin Exp Res (Alcoholism, clinical and experimental research)
[2020, 44(6):1234-1244]

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Making pharmacotherapy trials for substance use disorder more efficient: Leveraging real-world data capture to maximize power and expedite the medication development pipeline.

Ryan W Carpenter, Lindsay M Squeglia, Noah N Emery, Erin A McClure, Kevin M Gray, Robert Miranda, Rachel L Tomko,

Drug Alcohol Depend (Drug and alcohol dependence)
[2020, 209:107897]

Cited: 0 times

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Effect of alcohol use on the adolescent brain and behavior.

Briana Lees, Lindsay R Meredith, Anna E Kirkland, Brittany E Bryant, Lindsay M Squeglia,

Adolescence is a particularly vulnerable neurodevelopmental period marked by high rates of engagement with risky alcohol use. This review summarizes the cognitive and neural consequences following alcohol use during adolescence from longitudinal design studies in humans and animals. Findings from human adolescent studies suggest that binge drinking and heavy alcohol ... Read more >>

Pharmacol Biochem Behav (Pharmacology, biochemistry, and behavior)
[2020, 192:172906]

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Measuring Within-Individual Cannabis Reduction in Clinical Trials: A Review of the Methodological Challenges.

Rachel L Tomko, Kevin M Gray, Marilyn A Huestis, Lindsay M Squeglia, Nathaniel L Baker, Erin A McClure,

Purpose:Cannabis abstinence traditionally is the primary outcome in cannabis use disorder (CUD) treatment trials. Due to the changing legality of cannabis, patient goals, and preliminary evidence that suggests individuals who reduce their cannabis use may show functional improvements, cannabis reduction is a desirable alternative outcome in CUD trials. We review ... Read more >>

Curr Addict Rep (Current addiction reports)
[2019, 6(4):429-436]

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Efficacy and Safety of Varenicline for Adolescent Smoking Cessation: A Randomized Clinical Trial.

Kevin M Gray, Nathaniel L Baker, Erin A McClure, Rachel L Tomko, Lindsay M Squeglia, Michael E Saladin, Matthew J Carpenter,

Importance:Cigarette smoking is the leading cause of preventable morbidity and mortality in the United States and worldwide, and most tobacco users begin smoking in adolescence. Although advances have yielded efficacious pharmacotherapies to complement smoking cessation counseling in adults, far less progress has been made in addressing tobacco use in adolescence. ... Read more >>

JAMA Pediatr (JAMA pediatrics)
[2019, :]

Cited: 1 time

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Neurobiological and Cognitive Profile of Young Binge Drinkers: a Systematic Review and Meta-Analysis.

Briana Lees, Louise Mewton, Lexine A Stapinski, Lindsay M Squeglia, Caroline D Rae, Maree Teesson,

This review provides the first systematic and quantitative synthesis of the literature examining the relationship between binge drinking, cognition, brain structure and function in youth aged 10 to 24 years. PubMed, EMBASE, Medline, PsychINFO and ProQuest were searched for neuroimaging, neurophysiological, and neuropsychological studies. A total of 58 studies (21 neuroimaging, ... Read more >>

Neuropsychol Rev (Neuropsychology review)
[2019, 29(3):357-385]

Cited: 6 times

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Unconscious Bias and the Diagnosis of Disruptive Behavior Disorders and ADHD in African American and Hispanic Youth.

Matthew C Fadus, Kenneth R Ginsburg, Kunmi Sobowale, Colleen A Halliday-Boykins, Brittany E Bryant, Kevin M Gray, Lindsay M Squeglia,

Acad Psychiatry (Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry)
[2020, 44(1):95-102]

Cited: 1 time

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Depressive symptoms and cannabis use in a placebo-controlled trial of N-Acetylcysteine for adult cannabis use disorder.

Rachel L Tomko, Nathaniel L Baker, Caitlyn O Hood, Amanda K Gilmore, Erin A McClure, Lindsay M Squeglia, Aimee L McRae-Clark, Susan C Sonne, Kevin M Gray,

<h4>Rationale</h4>Depression is common among individuals with cannabis use disorder (CUD), particularly individuals who present to CUD treatment. Treatments that consider this comorbidity are essential.<h4>Objectives</h4>The goal of this secondary analysis was to examine whether N-acetylcysteine (NAC) reduced depressive symptoms among adults (age 18-50) with CUD (N = 302) and whether the effect of ... Read more >>

Psychopharmacology (Berl) (Psychopharmacology)
[2020, 237(2):479-490]

Cited: 1 time

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Behavioral Treatments for Adolescent Cannabis Use Disorder: a Rationale for Cognitive Retraining.

Laika D Aguinaldo, Lindsay M Squeglia, Kevin M Gray, Clarisa Coronado, Briana Lees, Rachel L Tomko, Joanna Jacobus,

Purpose of Review:Adolescent cannabis use represents a significant public health concern. Cannabis experimentation typically begins in adolescence and increases the odds of meeting criteria for cannabis use disorder. Cannabis use disorder is associated with numerous short- and long-term adverse consequences for adolescents, highlighting the critical need for efficacious behavioral treatments. ... Read more >>

Curr Addict Rep (Current addiction reports)
[2019, 6(4):437-442]

Cited: 2 times

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Double Dipping in Machine Learning: Problems and Solutions.

Tali M Ball, Lindsay M Squeglia, Susan F Tapert, Martin P Paulus,

Biol Psychiatry Cogn Neurosci Neuroimaging (Biological psychiatry. Cognitive neuroscience and neuroimaging)
[2020, 5(3):261-263]

Cited: 0 times

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Adolescent Substance Use Disorder Treatment: an Update on Evidence-Based Strategies.

Matthew C Fadus, Lindsay M Squeglia, Emilio A Valadez, Rachel L Tomko, Brittany E Bryant, Kevin M Gray,

<h4>Purpose of review</h4>To examine the most recent published evidence (2016-2019) regarding the treatment of adolescent substance use disorders and to provide an update on evidence-based strategies, adjunctive interventions, and methods to improve currently established treatment approaches.<h4>Recent findings</h4>Recent evidence suggests that psychosocial treatments such as family-based therapy, cognitive behavioral therapy, and ... Read more >>

Curr Psychiatry Rep (Current psychiatry reports)
[2019, 21(10):96]

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Convergent Evidence for Predispositional Effects of Brain Gray Matter Volume on Alcohol Consumption.

David A A Baranger, Catherine H Demers, Nourhan M Elsayed, Annchen R Knodt, Spenser R Radtke, Aline Desmarais, Lauren R Few, Arpana Agrawal, Andrew C Heath, Deanna M Barch, Lindsay M Squeglia, Douglas E Williamson, Ahmad R Hariri, Ryan Bogdan,

<h4>Background</h4>Alcohol use has been reliably associated with smaller subcortical and cortical regional gray matter volumes (GMVs). Whether these associations reflect shared predisposing risk factors or causal consequences of alcohol use remains poorly understood.<h4>Methods</h4>Data came from 3 neuroimaging samples (N = 2423), spanning childhood or adolescence to middle age, with prospective or ... Read more >>

Biol Psychiatry (Biological psychiatry)
[2020, 87(7):645-655]

Cited: 0 times

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Image processing and analysis methods for the Adolescent Brain Cognitive Development Study.

Donald J Hagler, SeanN Hatton, M Daniela Cornejo, Carolina Makowski, Damien A Fair, Anthony Steven Dick, Matthew T Sutherland, B J Casey, Deanna M Barch, Michael P Harms, Richard Watts, James M Bjork, Hugh P Garavan, Laura Hilmer, Christopher J Pung, Chelsea S Sicat, Joshua Kuperman, Hauke Bartsch, Feng Xue, Mary M Heitzeg, Angela R Laird, Thanh T Trinh, Raul Gonzalez, Susan F Tapert, Michael C Riedel, Lindsay M Squeglia, Luke W Hyde, Monica D Rosenberg, Eric A Earl, Katia D Howlett, Fiona C Baker, Mary Soules, Jazmin Diaz, Octavio Ruiz de Leon, Wesley K Thompson, Michael C Neale, Megan Herting, Elizabeth R Sowell, Ruben P Alvarez, Samuel W Hawes, Mariana Sanchez, Jerzy Bodurka, Florence J Breslin, Amanda Sheffield Morris, Martin P Paulus, W Kyle Simmons, Jonathan R Polimeni, Andre van der Kouwe, Andrew S Nencka, Kevin M Gray, Carlo Pierpaoli, John A Matochik, Antonio Noronha, Will M Aklin, Kevin Conway, Meyer Glantz, Elizabeth Hoffman, Roger Little, Marsha Lopez, Vani Pariyadath, Susan Rb Weiss, Dana L Wolff-Hughes, Rebecca DelCarmen-Wiggins, Sarah W Feldstein Ewing, Oscar Miranda-Dominguez, Bonnie J Nagel, Anders J Perrone, Darrick T Sturgeon, Aimee Goldstone, Adolf Pfefferbaum, Kilian M Pohl, Devin Prouty, Kristina Uban, Susan Y Bookheimer, Mirella Dapretto, Adriana Galvan, Kara Bagot, Jay Giedd, M Alejandra Infante, Joanna Jacobus, Kevin Patrick, Paul D Shilling, Rahul Desikan, Yi Li, Leo Sugrue, Marie T Banich, Naomi Friedman, John K Hewitt, Christian Hopfer, Joseph Sakai, Jody Tanabe, Linda B Cottler, Sara Jo Nixon, Linda Chang, Christine Cloak, Thomas Ernst, Gloria Reeves, David N Kennedy, Steve Heeringa, Scott Peltier, John Schulenberg, Chandra Sripada, Robert A Zucker, William G Iacono, Monica Luciana, Finnegan J Calabro, Duncan B Clark, David A Lewis, Beatriz Luna, Claudiu Schirda, Tufikameni Brima, John J Foxe, Edward G Freedman, Daniel W Mruzek, Michael J Mason, Rebekah Huber, Erin McGlade, Andrew Prescot, Perry F Renshaw, Deborah A Yurgelun-Todd, Nicholas A Allgaier, Julie A Dumas, Masha Ivanova, Alexandra Potter, Paul Florsheim, Christine Larson, Krista Lisdahl, Michael E Charness, Bernard Fuemmeler, John M Hettema, Hermine H Maes, Joel Steinberg, Andrey P Anokhin, Paul Glaser, Andrew C Heath, Pamela A Madden, Arielle Baskin-Sommers, R Todd Constable, Steven J Grant, Gayathri J Dowling, Sandra A Brown, Terry L Jernigan, Anders M Dale,

The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing, nationwide study of the effects of environmental influences on behavioral and brain development in adolescents. The main objective of the study is to recruit and assess over eleven thousand 9-10-year-olds and follow them over the course of 10 years to ... Read more >>

Neuroimage (NeuroImage)
[2019, 202:116091]

Cited: 5 times

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Orbitofrontal cortex volume prospectively predicts cannabis and other substance use onset in adolescents.

Natasha E Wade, Kara S Bagot, Claudia I Cota, Aryandokht Fotros, Lindsay M Squeglia, Lindsay R Meredith, Joanna Jacobus,

<h4>Background</h4>Identifying neural characteristics that predict cannabis initiation is important for prevention efforts. The orbitofrontal cortex is critical for reward response and may be vulnerable to substance-induced alterations.<h4>Aims</h4>We measured orbitofrontal cortex thickness, surface area, and volume prior to the onset of use to predict cannabis involvement during an average nine-year follow-up.<h4>Methods</h4>Adolescents ... Read more >>

J Psychopharmacol (Journal of psychopharmacology (Oxford, England))
[2019, 33(9):1124-1131]

Cited: 0 times

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The rise of e-cigarettes, pod mod devices, and JUUL among youth: Factors influencing use, health implications, and downstream effects.

Matthew C Fadus, Tracy T Smith, Lindsay M Squeglia,

<h4>Background</h4>Electronic cigarettes (e-cigarettes) were first introduced in the U.S. market in 2006, with the more recent evolution of "pod-mod" e-cigarettes such as JUUL introduced in 2015. Although marketed as a smoking cessation tool, e-cigarettes are rarely used for this purpose in youth. This review aims to synthesize the literature regarding ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2019, 201:85-93]

Cited: 12 times

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