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Hydrogenation of palmitic acid over Ni/Nb2O5-SiO2 catalyst: Synergetic effect and kinetic study

Shenzhi Yue, Lin Dong, Xiaohui Liu, Yong Guo, Yanqin Wang,

Hydrogenation is one of useful processes in the high valorization of biomass and the non-precious nickel based catalyst is one of promising catalysts owing to its high activity and low cost. Herein, we present a systematic investigation on the preparation, characterization and catalytic property of Ni/Nb₂O₅-SiO₂(x) catalysts in hydrogenation of ... Read more >>

(Industrial crops and products.)
[2021, 158:Not Available]

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DSCAM deficiency leads to premature spine maturation and autism-like behaviors.

Peng Chen, Ziyang Liu, Qian Zhang, Dong Lin, Song Lu, Jianghong Liu, Hui-Feng Jiao, Xinsheng Lai, Suqi Zou, Shunqi Wang, Tian Zhou, Bao-Ming Li, Li Zhu, Bing-Xing Pan, Erkang Fei,

Mutations in some cell adhesion molecules (CAMs) cause abnormal synapse formation and maturation, and serve as one of the potential mechanisms of autism spectrum disorders (ASDs). Recently, <i>DSCAM</i> (Down syndrome cell adhesion molecule) was found to be a high-risk gene for autism. However, it is still unclear how DSCAM contributes ... Read more >>

J Neurosci (The Journal of neuroscience : the official journal of the Society for Neuroscience)
[2021, :]

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Improving trial generalizability using observational studies.

Dasom Lee, Shu Yang, Lin Dong, Xiaofei Wang, Donglin Zeng, Jianwen Cai,

Complementary features of randomized controlled trials (RCTs) and observational studies (OSs) can be used jointly to estimate the average treatment effect of a target population. We propose a calibration weighting estimator that enforces the covariate balance between the RCT and OS, therefore improving the trial-based estimator's generalizability. Exploiting semiparametric efficiency ... Read more >>

Biometrics (Biometrics)
[2021, :]

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Revealing Key LncRNAs in Cytogenetically Normal Acute Myeloid Leukemia by Reconstruction of the LncRNA–miRNA–mRNA Network Based on the Competitive Endogenous RNA Theory

Tao Sun, Lin Dong, Yan Guo, Hai Zhao, Manzhi Wang,

<h4>Background: </h4> Cytogenetically normal acute myeloid leukemia(CN-AML) is a heterogeneous disease with different prognosis.Researches on prognostic indicators and therapy targets of CN-AML are still ongoing.Instead of protein-coding genes,more and more researches were focused on the non-coding RNAs especially long non-coding RNAs(lncRNAs) which may play an important role in the development ... Read more >>

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Transport and Mobility Needs for an Ageing Society from a Policy Perspective: Review and Implications.

Dong Lin, Jianqiang Cui,

The world population is ageing, and many countries in the world are confronted by significant challenges in adapting their health and social systems to meet the requirements of this demographic change. It is well-accepted that mobility is often closely linked to a person's independence, wellbeing and quality of life. Interest ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2021, 18(22):]

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Inhibition of GPR17 with cangrelor improves cognitive impairment and synaptic deficits induced by Aβ1-42 through Nrf2/HO-1 and NF-κB signaling pathway in mice.

ShiYu Jin, Xin Wang, XiaoTong Xiang, YuMei Wu, Jie Hu, YueYue Li, Yue Lin Dong, YueQiang Tan, Xian Wu,

The accumulation of amyloid beta (Aβ) in the brain is thought to be associated with cognitive deficits in Alzheimer's disease (AD). However, current methods to combat Aβ neurotoxicity are still lacking. G protein-coupled receptor 17 (GPR17) has become a target for treating inflammation in brain diseases, but it is unclear ... Read more >>

Int Immunopharmacol (International immunopharmacology)
[2021, 101(Pt B):108335]

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3D Printed MXene Aerogels with Truly 3D Macrostructure and Highly Engineered Microstructure for Enhanced Electrical and Electrochemical Performance.

Halil Tetik, Jafar Orangi, Guang Yang, Keren Zhao, Shakir Bin Mujib, Gurpreet Singh, Majid Beidaghi, Dong Lin,

Assembling 2D materials such as MXenes into functional 3D aerogels using 3D printing technologies gains attention due to simplicity of fabrication, customized geometry and physical properties, and improved performance. Also, the establishment of straightforward electrode fabrication methods with the aim to hinder the restack and/or aggregation of electrode materials, which ... Read more >>

Adv Mater (Advanced materials (Deerfield Beach, Fla.))
[2021, :e2104980]

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Patient-derived xenograft models of neuroendocrine prostate cancer.

Mingchen Shi, Yu Wang, Dong Lin, Yuzhuo Wang,

In recent years, patient-derived xenografts (PDXs) have attracted much attention as clinically relevant models for basic and translational cancer research. PDXs retain the principal histopathological and molecular heterogeneity of their donor tumors and remain stable across passages. These characteristics allow PDXs to offer a reliable platform for better understanding cancer ... Read more >>

Cancer Lett (Cancer letters)
[2022, 525:160-169]

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Interdigitating dendritic cell sarcoma located in the adrenal gland: a case report and literature review.

Peng Hao, Liang Cao, Yangming Li, Dong Lin, Tinghui Hu, Tao Wu,

We report a case of interdigitating dendritic cell sarcoma (IDCS) originating from the adrenal gland. A 57-year-old middle-aged woman with no previous history of malignancy came to our hospital after color Doppler ultrasound revealed a right adrenal mass. An abdominal computed tomography scan also showed an adrenal mass. Postoperative pathology ... Read more >>

J Int Med Res (The Journal of international medical research)
[2021, 49(11):3000605211055410]

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The gut microbiota confers the glucose-and lipid-lowering effect of Laurolitsine in db/db mice

Rui-qi Wang, Fang Zhang, Ya-nan Yang, Yin-feng Tan, Yong Zhang, Lin Dong, Ning Ma, Wei-ying Lu, Chong-ming Wu, Xiao-po Zhang,

<h4>Background: </h4> Modulations on gut microbiota by traditional Chinese medicines (TCMs) and their active components are emerging as potential therapeutic agents on diabetes. Litsea glutinosa is a TCM used in clinic to treat diabetes with alkaloids as the active constituents, and the Laurolitsine is the richest one. Purpose Based ... Read more >>

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A Refined Model of a Typhoon Near-Surface Wind Field Based on CFD

Youtian Yang, Lin Dong, Jiazi Li, Wenli Li, Dan Sheng, Hua Zhang,

Near-surface typhoon wind field simulation is a key method for high-precision typhoon hazard assessment and is of great significance for disaster forecast, loss risk assessment and emergency management. The terrain correction method for regional large-scale wind field simulation has a single correction method, which cannot satisfy the requirements of refined ... Read more >>

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Increased Uric Acid, Gamma-Glutamyl Transpeptidase and Alkaline Phosphatase in Early-Pregnancy Associated With the Development of Gestational Hypertension and Preeclampsia.

Yequn Chen, Weichao Ou, Dong Lin, Mengyue Lin, Xiru Huang, Shuhua Ni, Shaoxing Chen, Jian Yong, Mary Clare O'Gara, Xuerui Tan, Ruisheng Liu,

<b>Background:</b> Previous studies have reported that biomarkers of liver injury and renal dysfunction were associated with hypertensive disorders of pregnancy (HDP). However, the associations of these biomarkers in early pregnancy with the risk of HDP and longitudinal blood pressure pattern during pregnancy were rarely investigated in prospective cohort studies. <b>Methods:</b> ... Read more >>

Front Cardiovasc Med (Frontiers in cardiovascular medicine)
[2021, 8:756140]

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Active Substances from Callicarpa nudiflora Exert Anti-Cervicitis Effects and Regulate NLRP3-Associated Inflammation.

Tianchi Liu, Ruiqi Wang, Chenpeng Liu, Jiahong Lu, Yitao Wang, Lin Dong, Xiaopo Zhang,

Luohuazizhu suppository is a Traditional Chinese Medicine used in clinic to treat cervicitis, which is prepared from <i>Callicarpa nudiflora</i> Hook. et Arn (<i>C. nudiflora</i>), an herbal Chinese medicine named Luohuazizhu. This study aimed to figure out the active constituents of <i>C. nudiflora</i> and the potential mechanism for its anti-cervicitis effect. ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2021, 26(20):]

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A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway.

Xiaojing Zhang, Zhenzhen Liu, Shuaipeng Chen, Hang Li, Lin Dong, Xueyan Fu,

<h4>Ethnopharmacological relevance</h4>Bupleurum chinense DC has a history of using herb in China for more than 2000 years, which can be traced back to the Classic of Shennong Materia Medica in the Han Dynasty. Although Saikosaponin, the main active ingredient of Bupleurum, has the effects of anti-tumor, yet we still do ... Read more >>

J Ethnopharmacol (Journal of ethnopharmacology)
[2022, 283:114742]

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Two new scopadulane diterpenoids from Scoparia dulcis attenuated palmitate-induced viability in MIN6 cells.

Lin Dong, Wanying Sun, Zibao Huang, Caiyun Zhang, Chenpeng Liu, Xiaopo Zhang, Shouwen Zhang,

Two new scopadulane diterpenoids, termed Scopadulcic acids D (1, SDD) and E (2, SDE), together with two known analogues (3 and 4) were isolated from Scoparia dulcis. Their structures were elucidated by comprehensive spectroscopic analysis. The absolute configurations of 1 and 2 were determined by calculated electronic circular dichroism (ECD). ... Read more >>

Fitoterapia (Fitoterapia)
[2021, 155:105051]

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Manual Acupuncture at ST37 Modulates TRPV1 in Rats with Acute Visceral Hyperalgesia via Phosphatidylinositol 3-Kinase/Akt Pathway.

Caiyi Chen, Zhi Yu, Dong Lin, Xuan Wang, Xuejun Zhang, Feng Ji, Lingling He, Bin Xu,

Acupuncture can significantly ameliorate inflammatory pain in acute visceral hyperalgesia. Hyperalgesia is attenuated by inflammatory mediators that activate transient receptor potential vanilloid 1 (TRPV1), and TRPV1 is regulated by nerve growth factor (NGF)-induced phosphatidylinositol 3-kinase (PI3K)/Akt pathway. However, it is unknown whether NGF-induced PI3K/Akt pathway is associated with manual acupuncture ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2021, 2021:5561999]

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Multiomics analysis of tumor mutational burden across cancer types.

Lin Li, Long Bai, Huan Lin, Lin Dong, Rumeng Zhang, Xiao Cheng, Zexian Liu, Yi Ouyang, Keshuo Ding,

Whether tumor mutational burden (TMB) is related to improved survival outcomes or the promotion of immunotherapy in various malignant tumors remains controversial, and we lack a comprehensive understanding of TMB across cancers. Based on the data obtained from The Cancer Genome Atlas (TCGA), we conducted a multiomics analysis of TMB ... Read more >>

Comput Struct Biotechnol J (Computational and structural biotechnology journal)
[2021, 19:5637-5646]

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Phosphorescent Carbon-Nanodots-Assisted Förster Resonant Energy Transfer for Achieving Red Afterglow in an Aqueous Solution.

Ya-Chuan Liang, Qing Cao, Kai-Kai Liu, Xue-Yuan Peng, Lai-Zhi Sui, Shuang-Peng Wang, Shi-Yu Song, Xue-Ying Wu, Wen-Bo Zhao, Yuan Deng, Qing Lou, Lin Dong, Chong-Xin Shan,

Water-soluble red afterglow imaging agents based on ecofriendly nanomaterials have potential application in time-gated afterglow bioimaging due to their larger penetration depth and nondurable excitation. Herein, red afterglow imaging agents consisted of Rhodamine B (RhB) and carbon nanodots (CNDs) have been designed and demonstrated. In these agents, CNDs act as ... Read more >>

ACS Nano (ACS nano)
[2021, 15(10):16242-16254]

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Developing a reclamation strategy for softening nanofiltration brine: A scaling-free conversion approach via continuous two-stage electrodialysis metathesis.

Peng-Fei Li, Qing-Bai Chen, Jianyou Wang, Yong Xu, Lin Dong, Jin Wang,

A significant amount of concentrated, scaling-prone brine can be generated during the conversion of unconventional water resources to freshwater, thus necessitating the zero discharge of concentrated brine to meet environmental and resource requirements. In this study, a two-stage feed-and-bleed electrodialysis metathesis (FB-EDM) process was implemented to reclaim softening nanofiltration (SNF) ... Read more >>

Sci Total Environ (The Science of the total environment)
[2021, 807(Pt 1):150374]

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Application of Primary/Secondary Circulating Tumor Cells for the Prediction of Biochemical Recurrence in Nonmetastatic Prostate Cancer Patients following Radical Prostatectomy or Radiotherapy: A Meta-Analysis.

Liang Cao, Peng Hao, Dong Lin, Yangming Li, Tinghui Hu, Tao Cai, Shu Cui, Tao Wu,

<h4>Background</h4>Circulating tumor cells (CTCs) have been regarded as an independent prognostic marker for metastatic castration-resistant prostate cancer (mCRPC). Its prognostic value, however, in nonmetastatic prostate cancer (NMPC) is still unclear.<h4>Purpose</h4>To elucidate whether CTCs can predict the biochemical recurrence (BCR) in NMPC patients following radical prostatectomy (RP) or radiotherapy (RT).<h4>Methods</h4>PubMed, Cochrane ... Read more >>

Biomed Res Int (BioMed research international)
[2021, 2021:4730970]

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Surgical Clipping of Previously Coiled Recurrent Intracranial Aneurysms: A Single-Center Experience.

Yongtao Zheng, Lili Zheng, Yuhao Sun, Dong Lin, Baofeng Wang, Qingfang Sun, Liuguan Bian,

<b>Objective:</b> This study reviews our experiences in surgical clipping of previously coiled aneurysms, emphasizing on recurrence mechanism of intracranial aneurysms (IAs) and surgical techniques for different types of recurrent IAs. <b>Method:</b> We performed a retrospective study on 12 patients who underwent surgical clipping of aneurysms following endovascular treatment between January ... Read more >>

Front Neurol (Frontiers in neurology)
[2021, 12:680375]

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Efficacy of combination of venetoclax with azacitidine or chemotherapy in refractory/relapse acute leukemias of ambiguous lineage, not otherwise specified.

Kaiqi Liu, Yan Li, Shaowei Qiu, Chunlin Zhou, Shuning Wei, Dong Lin, Guangji Zhang, Hui Wei, Ying Wang, Bingcheng Liu, Xiaoyuan Gong, Qiuyun Fang, Yang Song, Huijun Wang, Chengwen Li, Qinghua Li, Lihua Wu, Benfa Gong, Yuntao Liu, Jianxiang Wang, Yingchang Mi,

Acute leukemias of ambiguous lineage, not otherwise specified (ALAL-NOS) is a rare type of acute leukemia. Management of relapse/refractory (R/R) patients is still challenging.traditional chemotherapy treatment is not effective. In this paper, we reported 6 R/R patients diagnosed as ALAL-NOS in our hospital, who were treated with venetoclax based treatment ... Read more >>

Exp Hematol Oncol (Experimental hematology & oncology)
[2021, 10(1):46]

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Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions.

Binghao Li, Hao Qu, Jing Zhang, Weibo Pan, Meng Liu, Xiaobo Yan, Xin Huang, Xuexin He, Dong Lin, Sisi Liu, Ruting Guan, Yong Wu, Qiuxiang Ou, Hua Bao, Youbin Xu, Xue Wu, Yang Shao, Nong Lin,

Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to identify the landscape of clinically relevant kinase fusions in Chinese lung cancer and to explore rare kinase rearrangements; thus, providing valuable evidence for therapeutic decision making. We ... Read more >>

NPJ Precis Oncol (NPJ precision oncology)
[2021, 5(1):81]

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Transformation of Highly Stable Pt Single Sites on Defect Engineered Ceria into Robust Pt Clusters for Vehicle Emission Control.

Wei Tan, Shaohua Xie, Yandi Cai, Meiyu Wang, Shuohan Yu, Ke-Bin Low, Yuejin Li, Lu Ma, Steven N Ehrlich, Fei Gao, Lin Dong, Fudong Liu,

Engineering surface defects on metal oxide supports could help promote the dispersion of active sites and catalytic performance of supported catalysts. Herein, a strategy of ZrO<sub>2</sub> doping was proposed to create rich surface defects on CeO<sub>2</sub> (CZO) and, with these defects, to improve Pt dispersion and enhance its affinity as ... Read more >>

Environ Sci Technol (Environmental science & technology)
[2021, 55(18):12607-12618]

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N6 -methyladenosine RNA methylation: A novel regulator of the development and function of immune cells.

Lin Dong, Yejin Cao, Yueru Hou, Guangwei Liu,

N<sup>6</sup> -methyladenosine (m<sup>6</sup> A) RNA methylation is a reversible posttranscriptional modification in eukaryotes involving three types of functional proteins: "writers", "erasers", and "readers". m<sup>6</sup> A regulates the metabolism of messenger RNAs and noncoding RNAs through RNA structure, splicing, stability, export, and translation, thereby participating in various physiological and pathological processes. ... Read more >>

J Cell Physiol (Journal of cellular physiology)
[2021, :]

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