Full Text Journal Articles by
Author Limin Zhao

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Distribution of complete blood count constituents in gestational diabetes mellitus.

Yonggang Zhang, Yipeng Zhang, Limin Zhao, Yanyan Shang, Dabao He, Jiying Chen,

<h4>Background trial design</h4>The incidence rate of gestational diabetes is high. In the long run, it harms the health of both the mother and child. In order to understand the distribution of hematological cells with gestational diabetes mellitus (GDM), a longitudinal cohort study was conducted from 2012 to 2018.<h4>Methods</h4>A longitudinal case ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(23):e26301]

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Tryptanthrin Regulates Vascular Smooth Muscle Cell Phenotypic Switching in Atherosclerosis by AMP-Activated Protein Kinase/Acetyl-CoA Carboxylase Signaling Pathway.

Xiujin Shi, Yi Zhang, Jialun Han, Wenxing Peng, Zhenwei Fang, Ying Qin, Xiaoyu Xu, Jie Lin, Fucheng Xiao, Limin Zhao, Yang Lin,

<h4>Abstract</h4>Atherosclerosis (AS) is one of the most severe cardiovascular diseases involved in the phenotypic switching of vascular smooth muscle cells (VSMCs). Tryptanthrin is a natural product with broad biological activities. However, the effect of tryptanthrin on atherosclerotic progression is unclear. The aim of this study was to determine the role ... Read more >>

J Cardiovasc Pharmacol (Journal of cardiovascular pharmacology)
[2021, 77(5):642-649]

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Endoscopic coblation treatment for congenital pyriform sinus fistula in children.

Wei Chen, Jiarui Chen, Fang Chen, Jiali Wu, Limin Zhao, Hongming Xu, Xiaoyan Li,

<h4>Abstract</h4>Congenital pyriform sinus fistula (CPSF) is a very rare branchial apparatus malformation. Traditional open surgery for fistulectomy might fail to excise the lesion completely, leading to continual recurrence. Herein, we report our experience of endoscopic coblation technique for treatment of CPSF in children.To observe the clinical efficacy of endoscopic coblation ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(19):e25942]

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The heterogeneity of fibroblasts in laryngotracheal stenosis and skin hypertrophic scar in pediatric patients.

Bin Hu, Jing Wang, Jiarui Chen, Limin Zhao, Xiaoyan Li,

<h4>Objectives</h4>To investigate the heterogeneity between the laryngotracheal stenosis and hypertrophic scar derived fibroblasts.<h4>Methods</h4>Human laryngotracheal stenosis (LTS) and skin hypertrophic scar (HTS) specimens were obtained during the tracheal resection and T-shaped tracheal stent implantation surgery. Fibroblasts were isolated and cultured. Cell proliferation and migration were analyzed by cell count, EdU proliferation ... Read more >>

Int J Pediatr Otorhinolaryngol (International journal of pediatric otorhinolaryngology)
[2021, 145:110709]

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PI3K/AKT/mTOR and TLR4/MyD88/NF-κB Signaling Inhibitors Attenuate Pathological Mechanisms of Allergic Asthma.

Baowei Ma, Seyyed Shamsadin Athari, Entezar Mehrabi Nasab, Limin Zhao,

Asthma is an inflammatory airway disease wherein bronchoconstriction, airway inflammation, and airway obstruction during asthma attacks are the main problems. It is recognized that imbalance of Th1/Th2 and Th17/Treg is a critical factor in asthma pathogenesis. Manipulation of these with signaling molecules such as mTOR, PI3K, Akt, and MyD88 can ... Read more >>

Inflammation (Inflammation)
[2021, :]

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Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite.

Su Duan, Limin Zhao, Yuling Zhang, Nan Zhang, Ming Zheng, Qiqi Wang, Xu Zhang, Xiangdong Wang, Sun Ying, Claus Bachert, Luo Zhang, Feng Lan,

<h4>Background</h4>Mugwort and house dust mite (HDM) are two of the most common inhalant allergens in Asia, however, whether mugwort affects polysensitized HDM<sup>+</sup> allergic rhinitis (AR) patients has not been elucidated.<h4>Methods</h4>Overall, 15,884 AR outpatients were assessed for clinical status. Amino acid sequences of mugwort were determined by mass spectrometry. Afterward, cross-reactivity ... Read more >>

Clin Mol Allergy (Clinical and molecular allergy : CMA)
[2021, 19(1):2]

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Preparation and in vitro/in vivo evaluation of a clonidine hydrochloride drug-resin suspension as a sustained-release formulation.

Hongfei Liu, Xiaoya Xie, Chao Chen, Caleb Kesse Firempong, Yingshu Feng, Limin Zhao, Xuezhi Yin,

<h4>Objective</h4>The purpose of the present study was to prepare a clonidine hydrochloride (CH) sustained-release suspension.<h4>Methods</h4>The processes involved in the drug formulation included drug loading, impregnating, and suspension preparation. Clonidine hydrochloride drug-resin complexes (CH-DRC) were prepared using the bath method and the CH-DRC impregnated before the microencapsulation process. Based on the ... Read more >>

Drug Dev Ind Pharm (Drug development and industrial pharmacy)
[2021, 47(3):394-402]

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Efficacy and Safety of Traditional Chinese medicine in patients with acute exacerbation of idiopathic pulmonary fibrosis: study protocol for randomized, controlled, exploratory clinical trial

Hailong Zhang, Jiansheng Li, Wen Guo, Lu Wang, Dong Zhang, Limin Zhao, Miao Zhou, Weixian Luo,

<h4>Background: </h4> At present, there is short of effective treatment for acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF). The treatment of IPF with Traditional Chinese medicine (TCM) has some advantages. However, the evidence is unclear whether TCM can be recommended as an effective therapy to treat AE-IPF. The purpose of ... Read more >>

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Fabricating Nanosheets and Ratiometric Detection of 5-Fluorouracil by Covalent Organic Framework Hybrid Material.

Jinmin Wang, Xianglong Qu, Limin Zhao, Bing Yan,

Covalent organic framework (COF) nanosheets (NSs) are a new member in the family of two-dimensional (2D) nanomaterials that received increasing attention. The ability to prepare COF NSs with rapid acquisition is of great importance to explore their distinctive properties and potential applications. Herein, we elaborate design a new COF hybrid ... Read more >>

Anal Chem (Analytical chemistry)
[2021, 93(9):4308-4316]

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Danthron attenuates experimental atherosclerosis by targeting foam cell formation.

Xiujin Shi, Yi Zhang, Baidi Lin, Yang Zhou, Wei Suo, Juanjuan Wei, Lin Zhang, Jie Lin, Fucheng Xiao, Limin Zhao, Yang Lin,

<h4>New findings</h4>What is the central question of this study? Does danthron alleviate experimental atherosclerosis by inhibiting the formation of foam cells? What are the main findings and their importance? Danthron improved serum lipid profiles and significantly reduced the atherosclerotic plaque areas and lipid accumulation in the aortic root of ApoE<sup>-/-</sup> ... Read more >>

Exp Physiol (Experimental physiology)
[2021, 106(3):653-662]

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Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ-Integrin αvβ5 Signaling Pathway.

Yi Zhang, Xiujin Shi, Jialun Han, Wenxing Peng, Zhenwei Fang, Yang Zhou, Xiaoyu Xu, Jie Lin, Fucheng Xiao, Limin Zhao, Yang Lin,

<h4>Introduction</h4>As the primary immune cells, macrophages play a key role in atherosclerotic progression. M2 macrophage polarization has been reported to promote tissue repair and attenuate plaque formation upon the expression of anti-inflammatory factors. Convallatoxin (CNT) is a natural cardiac glycoside with anti-inflammatory pharmacological properties. However, whether CNT protects against atherosclerosis ... Read more >>

Drug Des Devel Ther (Drug design, development and therapy)
[2021, 15:803-812]

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Superhydrophobic Self-Supporting BiOBr Aerogel for Wastewater Purification.

Jie Yue, Guochang Wen, Guina Ren, Shaowang Tang, Bo Ge, Limin Zhao, Xin Shao,

This research was focused on the raw material level construction of bismuth oxybromide (BiOBr) catalysis-loaded 3D cross-linked network polyurethane (PU) foam via the in situ polymerization method. After modification of superhydrophobic polydivinylbenzene nanoparticles, the PU foam possessed excellent superhydrophobic stability. The larger selective absorption oil phase capacity depended on its ... Read more >>

Langmuir (Langmuir : the ACS journal of surfaces and colloids)
[2021, 37(1):406-416]

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Metal-organic interface engineering for coupling palladium nanocrystals over functionalized graphene as an advanced electrocatalyst of methanol and ethanol oxidation.

Shuwen Li, Sizhuo Ma, Yixuan Zhang, Limin Zhao, Honglei Yang, Ruifa Jin,

Adjusting the surface structures and electronic structures of metal nanocrystals (NCs) by the metal-organic interface interaction is an emerging strategy to enhance their electrocatalytic behavior. In this work, the d-phenylalanine-functionalized graphene (DPHE-GS) anchoring Pd NCs (denoted as Pd/DPHE-GS) was fabricated via the diazo-reaction followed by a simple chemical reduction. Owing ... Read more >>

J Colloid Interface Sci (Journal of colloid and interface science)
[2021, 588:384-392]

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Bifunctional Carbon Dots Derived From an Anaerobic Bacterium of Porphyromonas gingivalis for Selective Detection of Fe3+ and Bioimaging.

Lijuan Liu, Kunhao Qin, Shuang Yin, Xiaodan Zheng, Hongmei Li, Hui Yan, Pengfei Song, Xiuling Ji, Qi Zhang, Yunlin Wei, Limin Zhao,

In this study, for the first time, Porphyromonas gingivalis, an anaerobic bacterium, was selected to synthesize carbon dots. The achieved P. gingivalis-carbon dots (Pg-CDs) exhibited strong fluorescence and high stability with capability for dual function as Fe<sup>3+</sup> sensor and intracellular imaging agent. The detection limit for Fe<sup>3+</sup> was as low as ... Read more >>

Photochem Photobiol (Photochemistry and photobiology)
[2021, 97(3):574-581]

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Effect of the BMPR-II-SMAD3/MRTF complex on proliferation and migration of ASMCs and the mechanism in asthma

Wenbo Gu, Jiahui Lei, Jing Xie, Yali Xiao, Zhenping Zhang, Limin Zhao,

Phenotype transformation of airway smooth muscle (ASM) is the key feature of airway remodelling in asthma. A variety of smooth muscle-specific genes and proteins, including SMAD3, BMPR-II, and MRTF, are involved in airway remodelling in asthma. Bone morphogenetic protein (BMP) signalling plays an important role in the physiological and pathological ... Read more >>

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[Lentivirus-mediated silencing of P75 neurotrophin receptor combined with nerve growth factor overexpression and transfection of bone marrow mesenchymal stem cells combined with demineralized bone matrix for heterotopic osteogenesis].

Junyi Chen, Ning Wang, Heng Zhang, Xianping Zhang, Limin Zhao, Lunjing Zhu, Zhijun Li, Chaoyong Bei,

<h4>Objective</h4>To investigate the effects of silencing P75 neurotrophin receptor (P75NTR) and nerve growth factor (NGF) overexpression on the proliferative activity and ectopic osteogenesis ability of bone marrow mesenchymal stem cells (BMSCs) combined with demineralized bone matrix for heterotopic osteogenesis.<h4>Methods</h4>BMSCs of Sprague Dawley (SD) rats were cultured and passaged by adherent ... Read more >>

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery)
[2020, 34(11):1438-1445]

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Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite

Feng Lan, Limin Zhao, Su Duan, Nan Zhang, Haibo Zhang, Ming Zheng, Qiqi Wang, Xu Zhang, Xiangdong Wang, Sun Ying, Claus Bachert, Luo Zhang,

<h4>ABSTRACT</h4> <h4>Background</h4> Mugwort and house dust mite (HDM) are two of the most common inhalant allergens in Asia; however, whether or not mugwort affects polysensitized HDM + allergic rhinitis (AR) patients has not been elucidated. <h4>Methods</h4> Overall, 15884 AR outpatients were assessed for clinical status. Amino acid sequences of mugwort ... Read more >>

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Response of patients with chest tightness variant asthma with routine asthma treatment regimen: A 1-year multicenter, prospective, real-world study.

Fugui Yan, Wen Li, Wei-Jie Guan, Min Chen, Chen Qiu, Wei Tang, Xiansheng Liu, Xudong Xiang, Jing Li, Meiling Jin, Yuanrong Dai, Ping Chen, Xiaohong Wu, Zhongmin Qiu, Liang Dong, Limin Zhao, Xiaoping Lin, Changgui Wu, Bin Wu, Yalian Yuan, Fei Shi, Ting Zhang, Jun Zhou, Min Xie, Xiaoyu Fang, Hongliang Zhang, Bing Xiao, Mo Xian, Jian Wang, Zhangwei Qiu, Jie Lin, Bingbing Ji, Yong Zhou, Yu Li, Chunhong Liu, Yiping Chen, Yiming Zeng, Yiming Zeng, Lingli Liu, Wen Hua, Huaqiong Huang, Jiesen Zhou, Yue Hu, Luanqing Che, Songmin Ying, Zhihua Chen, Nanshan Zhong, Huahao Shen,

<h4>Background</h4>Asthmatic patients with chest tightness as their only presenting symptom (chest tightness variant asthma [CTVA]) have clinical characteristics of eosinophilic airway inflammation similar to those of classic asthma (CA); however, whether CTVA has similar response to antiasthma treatment as compared with CA remains unclear.<h4>Objective</h4>The response of 76 CTVA patients to ... Read more >>

Clin Transl Med (Clinical and translational medicine)
[2020, 10(5):e178]

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OCT-Angiography Comparison between Obstructive Sleep Apnea Children and Normal Subjects in China.

Haiyun Ye, Chenjin Jin, Xiaoyan Li, Limin Zhao, Yuan Li, Tong Qiao,

<h4>Purpose</h4>Using optical coherence tomography angiography (OCT-A) to compare the retinal micro vessel alteration between obstructive sleep apnea (OSA) children and normal subjects.<h4>Methods</h4>One hundred-thirty-two eyes (132 participants) were recruited in this study. The average age of OSA group (66 eyes) and healthy control group (66 eyes) were 6.23 ± 1.73 and 6.76 ± 1.89 years, respectively. ... Read more >>

Curr Eye Res (Current eye research)
[2021, 46(3):355-360]

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Stability of Ebola Virus Immunoglobulin G Antibodies in Long-term Stored Samples.

Ning Zhang, Fei Liu, Junfeng Li, Hui Sui, Faming Miao, Teng Chen, Minghui Shao, Limin Zhao, Ruiyan Zhang, Jinghui Zhao,

J Infect Dis (The Journal of infectious diseases)
[2020, 222(6):1064-1065]

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[Determination of 10 pyrethroid pesticide residues in tea by gas chromatography-tandem mass spectrometry coupled with multi-plug filtration cleanup].

Yunxia Huang, Zhijuan Meng, Limin Zhao, Wenyi Sun, Dong Wang, Sufang Fan, Qiang Li, Yan Zhang,

A method for the determination of 10 pyrethroid pesticide residues in tea was established by multi-plug filtration cleanup (m-PFC) method combined with gas chromatography-tandem mass spectrometry (GC-MS/MS). Different extraction solvents (acetonitrile, acetone and ethyl acetate) and extraction methods (immersion without water and immersion with water) were compared. The effect of ... Read more >>

Se Pu (Se pu = Chinese journal of chromatography)
[2020, 38(7):798-804]

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LOXL1-AS1 Contributes to Non-Small Cell Lung Cancer Progression by Regulating miR-3128/RHOXF2 Axis.

Limin Zhao, Xuefei Zhang, Huannan Guo, Mingyang Liu, Liming Wang,

Purpose:The purpose of this study was to investigate the molecular mechanism of LncRNA LOXL1-AS1 in non-small cell lung cancer (NSCLC). Methods:Lung cancer cell lines (H1299, A549, H520 and H596) and human normal lung epithelial cell line (BEAS-2B) were used in this study. Gene expression was measured by qRT-PCR (quantitative real-time ... Read more >>

Onco Targets Ther (OncoTargets and therapy)
[2020, 13:6063-6071]

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Long Noncoding RNA CCAT1 Functions as a Competing Endogenous RNA to Upregulate ITGA9 by Sponging MiR-296-3p in Melanoma.

Jinghua Fan, Xiaoxiao Kang, Limin Zhao, Yan Zheng, Jun Yang, Di Li,

<h4>Background</h4>Melanoma is aggressive and lethal melanocytic neoplasm, and its incidence has increased worldwide in recent decades. Accumulating evidence has showed that various long noncoding RNAs (lncRNAs) participated in occurrence of malignant tumors, including melanoma. The present study was designed to investigate function of lncRNA colon cancer-associated transcript-1 (CCAT1) in melanoma.<h4>Methods</h4>The ... Read more >>

Cancer Manag Res (Cancer management and research)
[2020, 12:4699-4714]

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Diagnosis and treatment of congenital nasal dermoid and sinus cysts in 11 infants: A consort compliant study.

Kun Ni, Xiaoyan Li, Limin Zhao, Jiali Wu, Xiaojun Liu, Haibo Shi,

There have been few studies on congenital nasal dermoid and sinus cysts (NDSCs) in infants.This study was performed to obtain clinical data for the diagnosis and treatment of NDSCs in infants.We performed a retrospective analysis of 11 infants admitted with NDSCs between 2014 and 2019. Patient demographics, lesion site, preoperative ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(21):e19435]

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Natural killer cells and their function in Takayasu's arteritis.

Taotao Li, Na Gao, Wei Cui, Limin Zhao, Lili Pan,

OBJECTIVES:Takayasu's arteritis (TAK) is a chronic, large vessel systemic vasculitis. Immune inflammatory response plays a crucial role in the pathogenesis of TAK. Natural killer (NK) cells are one of the major immunoregulatory cell groups of the immune system, but their role in TAK pathogenesis is unclear. We aimed to investigate ... Read more >>

Clin Exp Rheumatol (Clinical and experimental rheumatology)
[2020, 38 Suppl 124(2):84-90]

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