Full Text Journal Articles by
Author Lilian Varga

Advertisement

Find full text journal articles






The Role of Mannose-binding Lectin in Infectious Complications of Pediatric Hemato-Oncologic Diseases.

Marianna Dobi, Ágnes Szilágyi, Dorottya Csuka, Lilian Varga, Zoltán Prohászka, Csaba Bereczki, Gábor Kovács, Ferenc Fekete,

The complement system is essential for protection against infections in oncologic patients because of the chemotherapy-induced immunosuppression. One of the key elements in the activation of the complement system via the lectin pathway is the appropriate functioning of mannose-binding lectin (MBL) and mannose-binding lectin-associated serine protease 2 (MASP2) complex. The ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(2):154-158]

Cited: 0 times

View full text PDF listing >>



The Importance of Complement Testing in Acquired Angioedema Related to Angiotensin-Converting Enzyme Inhibitors.

Zsuzsanna Balla, Zsuzsanna Zsilinszky, Zsófia Pólai, Noémi Andrási, Kinga Viktória Kőhalmi, Dorottya Csuka, Lilian Varga, Henriette Farkas,

<h4>Background</h4>Angiotensin-converting enzyme inhibitors may cause angioedema. Currently, no laboratory method is available for identifying acquired angioedema related to angiotensin-converting enzyme inhibitors. However, establishing the diagnosis is possible from the medical history and the preexisting angiotensin-converting enzyme inhibitor therapy, as well as by excluding other angioedema types.<h4>Objective</h4>To evaluate the results of ... Read more >>

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Patterns of C1-Inhibitor/Plasma Serine Protease Complexes in Healthy Humans and in Hereditary Angioedema Patients.

Erika Kajdácsi, Zsófia Jandrasics, Nóra Veszeli, Veronika Makó, Anna Koncz, Dominik Gulyás, Kinga Viktória Köhalmi, György Temesszentandrási, László Cervenak, Péter Gál, József Dobó, Steven de Maat, Coen Maas, Henriette Farkas, Lilian Varga,

C1-inhibitor (C1-INH) is an important regulator of the complement, coagulation, fibrinolytic and contact systems. The quantity of protease/C1-INH complexes in the blood is proportional to the level of the in vivo activation of these four cascade-like plasma enzyme systems. Parallel determination of C1-INH-containing activation complexes could be important to understand ... Read more >>

Front Immunol (Frontiers in immunology)
[2020, 11:794]

Cited: 0 times

View full text PDF listing >>



Definition, aims, and implementation of GA2 LEN/HAEi Angioedema Centers of Reference and Excellence.

Marcus Maurer, Werner Aberer, Rosana Agondi, Mona Al-Ahmad, Maryam Ali Al-Nesf, Ignacio Ansotegui, Rand Arnaout, Luisa Karla Arruda, Riccardo Asero, Emel Aygören-Pürsün, Aleena Banerji, Andrea Bauer, Moshe Ben-Shoshan, Alejandro Berardi, Jonathan A Bernstein, Stephen Betschel, Carsten Bindslev-Jensen, Mojca Bizjak, Isabelle Boccon-Gibod, Konrad Bork, Laurence Bouillet, Henrik Balle Boysen, Nicholas Brodszki, Sigurd Broesby-Olsen, Paula Busse, Thomas Buttgereit, Anette Bygum, Teresa Caballero, Régis A Campos, Mauro Cancian, Ivan Cherrez-Ojeda, Danny M Cohn, Célia Costa, Timothy Craig, Paulo Ricardo Criado, Roberta F Criado, Dorottya Csuka, Joachim Dissemond, Aurélie Du-Thanh, Luis Felipe Ensina, Ragıp Ertaş, José E Fabiani, Claudio Fantini, Henriette Farkas, Silvia Mariel Ferrucci, Ignasi Figueras-Nart, Natalia L Fili, Daria Fomina, Atsushi Fukunaga, Asli Gelincik, Ana Giménez-Arnau, Kiran Godse, Mark Gompels, Margarida Gonçalo, Maia Gotua, Richard Gower, Anete S Grumach, Guillermo Guidos-Fogelbach, Michihiro Hide, Natalia Ilina, Naoko Inomata, Thilo Jakob, Dario O Josviack, Hye-Ryun Kang, Allen Kaplan, Alicja Kasperska-Zając, Constance Katelaris, Aharon Kessel, Andreas Kleinheinz, Emek Kocatürk, Mitja Košnik, Dorota Krasowska, Kanokvalai Kulthanan, M Sendhil Kumaran, José Ignacio Larco Sousa, Hilary J Longhurst, William Lumry, Andrew MacGinnitie, Markus Magerl, Michael P Makris, Alejandro Malbrán, Alexander Marsland, Inmaculada Martinez-Saguer, Iris V Medina, Raisa Meshkova, Martin Metz, Iman Nasr, Jan Nicolay, Chikako Nishigori, Isao Ohsawa, Kemal Özyurt, Nikolaos G Papadopoulos, Claudio A S Parisi, Jonathan Grant Peter, Wolfgang Pfützner, Todor Popov, Nieves Prior, German D Ramon, Adam Reich, Avner Reshef, Marc A Riedl, Bruce Ritchie, Heike Röckmann-Helmbach, Michael Rudenko, Andaç Salman, Mario Sanchez-Borges, Peter Schmid-Grendelmeier, Faradiba S Serpa, Esther Serra-Baldrich, Farrukh R Sheikh, William Smith, Angèle Soria, Petra Staubach, Urs C Steiner, Marcin Stobiecki, Gordon Sussman, Anna Tagka, Simon Francis Thomsen, Regina Treudler, Solange Valle, Martijn van Doorn, Lilian Varga, Daniel O Vázquez, Nicola Wagner, Liangchun Wang, Christina Weber-Chrysochoou, Young-Min Ye, Anna Zalewska-Janowska, Andrea Zanichelli, Zuotao Zhao, Yuxiang Zhi, Torsten Zuberbier, Ricardo D Zwiener, Anthony Castaldo,

Allergy (Allergy)
[2020, 75(8):2115-2123]

Cited: 0 times

View full text PDF listing >>



Clinical Characteristics and Safety of Plasma-Derived C1-Inhibitor Therapy in Children and Adolescents with Hereditary Angioedema-A Long-Term Survey.

Henriette Farkas, Kinga Viktória Kőhalmi, Beáta Visy, Nóra Veszeli, Lilian Varga,

BACKGROUND:Plasma-derived C1-inhibitor (pdC1-INH) is a first-line therapy for hereditary angioedema (HAE) with C1-inhibitor deficiency (C1-INH-HAE) in pediatric patients. OBJECTIVE:We intended to study the clinical characteristics and safety of treatment with pdC1-INH in this population. METHODS:In the prospective, long-term survey, real-world data on pdC1-INH (Berinert, CSL Behring) use in pediatric patients, ... Read more >>

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2020, 8(7):2379-2383]

Cited: 0 times

View full text PDF listing >>



Changes of coagulation parameters during erythema marginatum in patients with hereditary angioedema.

Kinga Viktória Kőhalmi, Blanka Mező, Nóra Veszeli, Szabolcs Benedek, Adrienne Fehér, Ágnes Holdonner, Milos Jesenak, Lilian Varga, Henriette Farkas,

<h4>Background</h4>Hereditary angioedema (HAE) with C1-inhibitor deficiency (C1-INH-HAE) is characterized by recurrent episodes of subcutaneous/submucosal edema, which may be preceded by erythema marginatum (EM) as a prodromal symptom. Our aim was to analyze the changes occurring in the parameters of the coagulation system during the development of EM and HAE attacks.<h4>Materials ... Read more >>

Int Immunopharmacol (International immunopharmacology)
[2020, 81:106293]

Cited: 0 times

View full text PDF listing >>



Evaluation of the efficacy and safety of home treatment with the recombinant human C1-inhibitor in hereditary angioedema resulting from C1-inhibitor deficiency.

Noémi Andrási, Nóra Veszeli, Ágnes Holdonner, György Temesszentandrási, Kinga Viktória Kőhalmi, Lilian Varga, Henriette Farkas,

OBJECTIVE:Conestat alpha, a C1-inhibitor produced by recombinant technology (rhC1-INH) is an acute treatment for edematous attacks occurring in hereditary angioedema (HAE) with C1-inhibitor deficiency (C1-INH-HAE). Our study evaluated the efficacy and safety of rhC1-INH administered during HAE attacks, and for short-term prophylaxis (STP). MATERIALS & METHOD:Our prospective study analyzed the ... Read more >>

Int Immunopharmacol (International immunopharmacology)
[2020, 80:106216]

Cited: 0 times

View full text PDF listing >>



[Analysis of the relationship between vitamin D3 level and disease severity in hereditary angioedema].

Beáta Visy, Tamás Szilágyi, Kinga Viktória Kőhalmi, Nóra Veszeli, Lilian Varga, Éva Imreh, Henriette Farkas,

<i>Introduction:</i> In recent years, many papers analyzed the relationship between serum vitamin D<sub>3</sub> level and the frequency and activity of various diseases at least partially attributed to immune mechanisms. <i>Aim:</i> We looked for correlations among the number and location of edematous episodes occurring in patients with hereditary angioedema due to ... Read more >>

Orv Hetil (Orvosi hetilap)
[2019, 160(25):987-993]

Cited: 0 times

View full text PDF listing >>



Idiopathic Nonhistaminergic Acquired Angioedema Versus Hereditary Angioedema.

Noémi Andrási, Nóra Veszeli, Kinga Viktória Kőhalmi, Dorottya Csuka, György Temesszentandrási, Lilian Varga, Henriette Farkas,

BACKGROUND:The mechanism of idiopathic nonhistaminergic acquired angioedema (InH-AAE) has not yet been precisely elucidated. This condition is characterized by recurrent angioedema without wheals. OBJECTIVE:To study the clinical features of InH-AAE, and to make, for the first time, independent comparisons with hereditary angioedema of unknown origin (U-HAE), as well as with hereditary ... Read more >>

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2018, 6(4):1205-1208]

Cited: 1 time

View full text PDF listing >>



[Effect of danazol treatment on growth in pediatric patients with hereditary angioedema due to C1-inhibitor deficiency].

Kinga Viktória Kőhalmi, Nóra Veszeli, Andrea Luczay, Lilian Varga, Henriette Farkas,

<h4>Introduction</h4>Attenuated androgens are used for the prevention of angioedema attacks of hereditary angioedema with C1-inhibitor deficiency. After prepuberty, their use can lead to growth retardation.<h4>Aim</h4>We assessed the effect of danazol on the growth of pediatric patients with hereditary angioedema.<h4>Method</h4>In the retrospective study on 42 patients diagnosed with hereditary angioedema, we ... Read more >>

Orv Hetil (Orvosi hetilap)
[2017, 158(32):1269-1276]

Cited: 1 time

View full text PDF listing >>



The role of the complement system in hereditary angioedema.

Dorottya Csuka, Nóra Veszeli, Lilian Varga, Zoltán Prohászka, Henriette Farkas,

Hereditary angioedema (HAE) is a rare, but potentially life-threatening disorder, characterized by acute, recurring, and self-limiting edematous episodes of the face, extremities, trunk, genitals, upper airways, or the gastrointestinal tract. HAE may be caused by the deficiency of C1-inhibitor (C1-INH-HAE) but another type of the disease, hereditary angioedema with normal ... Read more >>

Mol Immunol (Molecular immunology)
[2017, 89:59-68]

Cited: 10 times

View full text PDF listing >>



A novel prophylaxis with C1-inhibitor concentrate in hereditary angioedema during erythema marginatum.

Kinga Viktória Kőhalmi, Nóra Veszeli, László Cervenak, Lilian Varga, Henriette Farkas,

<h4>Background</h4>Hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) is a rare, autosomal dominant disorder. The characteristic episodes of subcutaneous/submucosal edema formation may be preceded by erythema marginatum (EM) - the occurrence of a 'map-like' pattern on the skin. EM can occur as an isolated finding or accompanying a hereditary angiooedema (HAE) attack ... Read more >>

Immunol Lett (Immunology letters)
[2017, 189:90-93]

Cited: 1 time

View full text PDF listing >>



Reply.

Kusumam Joseph, Rosemeire N Constantino-Silva, Anete S Grumach, Anna Feldweg, Lakiea Wright, Natasha Frank, Dana Vuzman, Rohit Sharma, Chiara Suffritti, Marco Cicardi, Lilian Varga, Henriette Farkas, Konrad Bork, Allen P Kaplan,

J Allergy Clin Immunol (The Journal of allergy and clinical immunology)
[2017, 139(5):1720-1721]

Cited: 2 times

View full text PDF listing >>



"Nuts and Bolts" of Laboratory Evaluation of Angioedema.

Henriette Farkas, Nóra Veszeli, Erika Kajdácsi, László Cervenak, Lilian Varga,

Angioedema, as a distinct disease entity, often becomes a clinical challenge for physicians, because it may cause a life-threatening condition, whereas prompt and accurate laboratory diagnostics may not be available. Although the bedside diagnosis needs to be established based on clinical symptoms and signs, family history, and the therapeutic response, ... Read more >>

Clin Rev Allergy Immunol (Clinical reviews in allergy & immunology)
[2016, 51(2):140-151]

Cited: 11 times

View full text PDF listing >>



Abstracts from the 10th C1-inhibitor deficiency workshop

Alvin H. Schmaier, Marco Cicardi, Avner Reshef, Dumitru Moldovan, Attila Mócsai, Margarita López-Trascasa, Alberto López Lera, Nancy J. Brown, Anastasios E. Germenis, Rafael Filippelli-Silva, Diego A. Duarte, Renan P. Martin, Camila L. Veronez, Michel Bouvier, Michael Bader, Claudio M. Costa-Neto, João Bosco Pesquero, Xavier Charest-Morin, François Marceau, Georges-É. Rivard, Arnaud Bonnefoy, Éric Wagner, Márta L. Debreczeni, Zsuzsanna Németh, Erika Kajdácsi, Endre Schwaner, László Cervenak, Gábor Oroszlán, András Szilágyi, Ráhel Dani, Péter Závodszky, Péter Gál, József Dobó, Jacques Hébert, Matthieu Vincent, Jean-Nicolas Boursiquot, Hugo Chapdeleine, Marylin Desjardins, Benoit Laramée, Rémi Gagnon, Nancy Payette, Oleksandra Lepeshkina, Delphine Charignon, Arije Ghannam, Denise Ponard, Christian Drouet, Kusumam Joseph, Baby G. Tholanikunnel, Daniel J. Sexton, Allen P. Kaplan, Stefania Loffredo, Maria Bova, Anne Lise Ferrara, Angelica Petraroli, Chiara Suffritti, Nóra Veszeli, Andrea Zanichelli, Henriette Farkas, Gianni Marone, Samuel Luyasu, Bertrand Favier, Ludovic Martin, Kinga Viktória Kőhalmi, György Temesszentandrási, Katalin Várnai, Lilian Varga, Bruce L. Zuraw, Annette Feussner, Michael A. Tortorici, Dipti Pawaskar, Huamin Henry Li, John Anderson, Jonathan A. Bernstein, Ying Zhang, Ingo Pragst, on behalf of COMPACT investigators, Emel Aygören-Pürsün, Kraig Jacobson, Jim Christensen, Arthur Van Leerberghe, Yi Wang, Jennifer Schranz, Inmaculada Martinez-Saguer, Daniel Soteres, Urs Steiner, Vesna Grivcheva Panovska, William Rae, Werner Aberer, Aarnoud Huissoon, Anette Bygum, Markus Magerl, Jochen Graff, Hilary Longhurst, Ramón Lleonart, Lei Fang, Melanie Cornpropst, Desiree Clemons, Amanda Mathis, Phil Collis, Sylvia Dobo, William P. Sheridan, Marcus Maurer, Marc A. Riedl, Timothy Craig, Aleena Banerji, Mustafa Shennak, William Yang, Jovanna Baptista, Paula Busse, Ira Kalfus, Andrew McDonald, Shawn Qian, Anthony Roberts, Con Panousis, Tim Green, Andreas Gille, Maria Zamanakou, Gedeon Loules, Dorottya Csuka, Fotis Psarros, Faidra Parsopoulou, Matthaios Speletas, Davide Firinu, Tiziana Maria Angela De Pasquale, Alessandra Zoli, Anna Radice, Stefano Pizzimenti, Emmanouil Manoussakis, George N. Konstantinou, Valeria Bafunno, Vincenzo Montinaro, Mauro Cancian, Maurizio Margaglione, Konrad Bork, Karin Wulff, Guenther Witzke, Jochen Hardt, Laurence Bouillet, Teresa Caballero, Anete S. Grumach, Christelle Pommie, Irmgard Andresen, Carmen Escuriola Ettingshausen, Zeynep Gutowski, Karin Andritschke, Richard Linde, Noémi Andrási, Tamás Szilágyi, Iris Leibovich-Nassi, Christine Symons, John Dempster, Isabelle Boccon-Gibod, Anne Pagnier, Audrey Lehmann, Kristian B. Kreiberg, Sandra A. Nieto, Raquel Martins, Renata Martins, Alejandra Menendez, Solange O. R. Valle, Margarita Olivares, Maria E. Hernandez-Landeros, Elma Nievas, Natalia Fili, Olga M. Barrera, René Bailleau, Ana Maria Gallardo-Olivos, Masumi Grau, Julian Rodriguez-Galindo, Marlon J. O. Carabantes, Edison Zapata-Venegas, Mario Martinez Alfonso, Maria Rosario-Grauert, Manuel Ratti, Daniel Vaszquez, Dario Josviack, Luis Fernando Landivar-Salinas, Oscar M. E. Calderón-Llosa, Rolando Campilay-Sarmiento, Pablo Raby, Jose Fabiani, William R. Lumry, Henrike Feuersenger, Douglas J. Watson, Thomas Machnig, on behalf of the Investigators of the COMPACT study, Donatella Lamacchia, Adriana Hernanz, Ana Alvez, Mariana Lluncor, Maria Pedrosa, Rosario Cabañas, Nieves Prior, Patrik Nordenfelt, Mats Nilsson, Anders Lindfors, Carl-Fredrik Wahlgren, Janne Björkander, Roman Hakl, Pavel Kuklínek, Irena Krčmová, Jana Hanzlíková, Martina Vachová, Radana Zachová, Marta Sobotková, Jana Strenková, Jiří Litzman, Maria Palasopoulou, Gerasimina Tsinti, Panagiota Gianni, Maria Kompoti, Sofia Garrido, Wojciech Dyga, Anna Bogdali, Aleksander Obtułowicz, Mikolajczyk Tomasz, Ewa Czarnobilska, Krystyna Obtulowicz, Teofila Książek, Anna Koncz, Dominik Gulyás, Maria Staevska, Milos Jesenak, Katarina Hrubiskova, L. Bellizzi, A. Relan, Maddalena A. Wu, Antonio Castelli, Riccardo Colombo, Gianmarco Podda, Marta Del Medico, Emanuele Catena, Francesco Casella, Francesca Perego, Nada Afifi Afifi, Eleonora Tobaldini, Nicola Montano, for the IOS Study Group, Marta Sánchez-Jareño, Marcin Stobiecki, Krystyna Obtułowicz, Irina Guryanova, Ekaterina Polyakova, Viktar Lebedz, Andrej Salivonchik, Svetlana Aleshkevich, Mikhail Belevtsev, Melanie Nordmann-Kleiner, Susanne Trainotti, Janina Hahn, Jens Greve, Liudmyla Zabrodska, Maria L. Oliva Alonso, Rosangela P. Tórtora, Alfeu T. França, Marcia G. Ribeiro, Lisa Fu, Amin Kanani, Gina Lacuesta, Susan Waserman, Stephen Betschel, Melissa I. Espinosa, Francisco A. Contreras, Martin Hrubisko, Ludmila Vavrova, Peter Banovcin, Maryam Ayazi, Mohammad Reza Fazlollahi, Shiva Saghafi, Sajedeh Mohammadian, Susan Nabilou Deshiry, Kiana Bidad, Raheleh Shokouhi Shoormasti, Iraj Mohammadzadeh, Mohammad Hassan Bemanian, Seyed Alireza Mahdaviani, Zahra Pourpak, Anna Valerieva, Mariela Vasileva, Tsvetelina Velikova, Elena Petkova, Vasil Dimitrov, Ruggero Di Maulo, on behalf of participating centers, Raz Somech, Hava Golander, Erika J. Sifuentes, Catherine Mansard, Anne Gompel, Bernard Floccard, Claire Blanchard-Delaunay, David Launay, Olivier Fain, Alain Sobel, Stéphane Gayet, Stéphanie Amarger, Guillaume Armengol, Yann Ollivier, Ariane Zélinsky-Gurung, Pierre-Yves Jeandel, Gisèle Kanny, Brigitte Coppéré, Marie Dubrel, Fabien Pelletier, Aurélie Du Thanh, Sébastien Trouiller, Jérôme Laurent, Claire De Moreuil, Christine Audouin Pajot, Alexandre Belot, Ana Rodríguez, Dasha Roa, Alicia Prieto, Maria Luisa Baeza, Borislava Krusheva, Stephanie K. A. Almeida, Rosemeire N. Constantino-Silva, Nyla Melo, Joanna Araujo Simoes, Sandra Mitie U. Palma, Jane da Silva, Bruna F. de Azevedo, Eli Mansour, Teresa González-Quevedo, Carmen Marcos, Teófilo Lobera, Blanca Sáenz de San Pedro, Ernie Avilla, Jacquie Badiou, Karen Binkley, Rozita Borici-Mazi, Linda Howlett, Paul K. Keith, Anne Rowe, Peter Waite, Aurore Billebeau, Isabelle Boccon-Gibbod, Kristina Lis, Yael Laitman, Eitan Friedman, N. M. Gokmen, O. Gulbahar, H. Onay, Z. P. Koc, A. Z. Sin,

Allergy Asthma Clin Immunol (Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology)
[2017, 13(Suppl 2):]

Cited: 0 times

View full text PDF listing >>



Alternative complement pathway activation during invasive coronary procedures in acute myocardial infarction and stable angina pectoris.

Zsófia Horváth, Dorottya Csuka, Katarina Vargova, Andrea Kovács, Sarolta Leé, Lilian Varga, István Préda, Emese Tóth Zsámboki, Zoltán Prohászka, Róbert Gábor Kiss,

The effect of invasive percutaneous coronary procedures on complement activation has not been elucidated. We enrolled stable angina patients with elective percutaneous coronary intervention (SA-PCI, n=24), diagnostic coronary angiography (CA, n=52) and 23 patients with ST segment elevation myocardial infarction and primary PCI (STEMI-PCI). Complement activation products (C1rC1sC1inh, C3bBbP and ... Read more >>

Clin Chim Acta (Clinica chimica acta; international journal of clinical chemistry)
[2016, 463:138-144]

Cited: 3 times

View full text PDF listing >>



Assessment of inhibitory antibodies in patients with hereditary angioedema treated with plasma-derived C1 inhibitor.

Henriette Farkas, Lilian Varga, Dumitru Moldovan, Krystyna Obtulowicz, Todor Shirov, Thomas Machnig, Henrike Feuersenger, Jonathan Edelman, Debora Williams-Herman, Mikhail Rojavin,

<h4>Background</h4>Limited data are available regarding C1 inhibitor (C1-INH) administration and anti-C1-INH antibodies.<h4>Objective</h4>To assess the incidence of antibody formation during treatment with pasteurized, nanofiltered plasma-derived C1-INH (pnfC1-INH) in patients with hereditary angioedema with C1-INH deficiency (C1-INH-HAE) and the comparative efficacy of pnfC1-INH in patients with and without antibodies.<h4>Methods</h4>In this multicenter, open-label ... Read more >>

Ann Allergy Asthma Immunol (Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology)
[2016, 117(5):508-513]

Cited: 3 times

View full text PDF listing >>



Thyroid hormones and complement parameters in hereditary angioedema with C1-inhibitor deficiency.

Ibolya Czaller, Dorottya Csuka, Zsuzsanna Zotter, Nóra Veszeli, Edit Takács, Éva Imreh, Lilian Varga, Henriette Farkas,

<h4>Background</h4>Thyroid hormones control and up-regulate the synthesis of many plasma proteins.<h4>Objective</h4>To explore possible associations between thyroid hormone and complement levels in patients with hereditary angioedema resulting from the deficiency of the C1-inhibitor (C1-INH-HAE).<h4>Methods</h4>In this case-control study, serum thyrotropin, free triiodothyronine (FT3), and free thyroxine (FT4) levels, anti-thyroid peroxidase and antithyroglobulin ... Read more >>

Ann Allergy Asthma Immunol (Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology)
[2016, 117(2):175-179]

Cited: 1 time

View full text PDF listing >>



Novel Vasoregulatory Aspects of Hereditary Angioedema: the Role of Arginine Vasopressin, Adrenomedullin and Endothelin-1.

Erika Kajdácsi, Péter K Jani, Dorottya Csuka, Lilian Varga, Zoltán Prohászka, Henriette Farkas, László Cervenak,

The elevation of bradykinin (BK) level during attacks of hereditary angioedema due to C1-Inhibitor deficiency (C1-INH-HAE) is well known. We previously demonstrated that endothelin-1 (ET-1) level also increases during C1-INH-HAE attacks. Although BK and ET-1 are both potent vasoactive peptides, the vasoregulatory aspect of the pathomechanism of C1-INH-HAE has not ... Read more >>

J Clin Immunol (Journal of clinical immunology)
[2016, 36(2):160-170]

Cited: 3 times

View full text PDF listing >>



First report of icatibant treatment in a pregnant patient with hereditary angioedema.

Henriette Farkas, Kinga Viktória Kőhalmi, Nóra Veszeli, Ferenc Tóth, Lilian Varga,

Hereditary angioedema resulting from C1-inhibitor deficiency (C1-INH-HAE) is a rare, autosomal dominant disorder, characterized by recurrent attacks of edema formation. The management of pregnant patients with C1-INH-HAE is often a challenge for the physician. There is limited experience with novel therapies. Plasma-derived nanofiltered C1-INH (pnfC1-INH) is the only recommended therapeutic ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2016, 42(8):1026-1028]

Cited: 5 times

View full text PDF listing >>



The effect of long-term danazol treatment on haematological parameters in hereditary angioedema.

Kinga Viktória Kőhalmi, Nóra Veszeli, Zsuzsanna Zotter, Dorottya Csuka, Szabolcs Benedek, Éva Imreh, Lilian Varga, Henriette Farkas,

<h4>Background</h4>The 17-alpha-alkylated derivatives of testosterone are often used for the prevention of oedematous episodes in hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE). However, these agents can have many adverse effects, including erythrocytosis and polyglobulia. Our aim was to investigate occurrence of erythrocytosis and polyglobulia after long-term danazol prophylaxis in C1-INH-HAE.<h4>Methods</h4>During the ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2016, 11:18]

Cited: 2 times

View full text PDF listing >>



Atrial natriuretic peptide as a novel biomarker of hereditary angioedema.

Erika Kajdácsi, Lilian Varga, Zoltán Prohászka, Henriette Farkas, László Cervenak,

Clin Immunol (Clinical immunology (Orlando, Fla.))
[2016, 165:45-46]

Cited: 1 time

View full text PDF listing >>



Comprehensive study into the activation of the plasma enzyme systems during attacks of hereditary angioedema due to C1-inhibitor deficiency.

Dorottya Csuka, Nóra Veszeli, Éva Imreh, Zsuzsanna Zotter, Judit Skopál, Zoltán Prohászka, Lilian Varga, Henriette Farkas,

<h4>Background</h4>The activation of plasma enzyme systems contributes to hereditary angioedema attacks. We aimed to study the activation markers of the fibrinolytic, coagulation, and contact systems in a larger number of paired samples obtained from the same C1-INH-HAE patients in symptom-free periods and during attacks.<h4>Methods</h4>Eleven parameters (Factors XI, XII, and C1-inhibitor ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2015, 10:132]

Cited: 15 times

View full text PDF listing >>



Risk of thromboembolism in patients with hereditary angioedema treated with plasma-derived C1-inhibitor.

Henriette Farkas, Kinga V Kőhalmi, Nóra Veszeli, Zsuzsanna Zotter, Katalin Várnai, Lilian Varga,

<h4>Background</h4>Plasma-derived C1-inhibitor (C1-INH) concentrates (pdC1-INH) have been used as safe and effective treatments for hereditary angioedema with C1-INH deficiency (C1-INH-HAE) for >30 years. Notwithstanding this, sporadic reports and a study into the high-dose therapy of neonates with C1-INH concentrate administered in an off-label indication raised concerns that this drug might ... Read more >>

Allergy Asthma Proc (Allergy and asthma proceedings)
[2016, 37(2):164-170]

Cited: 6 times

View full text PDF listing >>



Neutrophil activation during attacks in patients with hereditary angioedema due to C1-inhibitor deficiency.

Nóra Veszeli, Dorottya Csuka, Zsuzsanna Zotter, Éva Imreh, Mihály Józsi, Szabolcs Benedek, Lilian Varga, Henriette Farkas,

<h4>Background</h4>Earlier studies have shown that the absolute number of neutrophil granulocytes (NGs) may increase during attack of hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE). Whether NGs undergo activation during attack has not yet been investigated. However, as neutrophil elastase (NE) can cleave and inactivate C1-INH which may contribute to the ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2015, 10:156]

Cited: 9 times

View full text PDF listing >>



Advertisement

Disclaimer
2.3146 s