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Author Lihua Tang

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MiR-451a restrains the growth and metastatic phenotypes of papillary thyroid carcinoma cells via inhibiting ZEB1.

Qiong Wang, Jing Shang, Yun Zhang, Yan Zhou, Lihua Tang,

MicroRNAs (miRNAs) are known to be critical regulators in cancer progression. MiR-451a is reported to be involved in the progression of many different forms of cancers, including osteosarcoma, colorectal cancer, and breast carcinoma. In this study, we illuminated the possible roles of miR-451a in the development of papillary thyroid carcinoma ... Read more >>

Biomed. Pharmacother. (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie)
[2020, 127:109901]

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Untargeted Metabolite Profiling of Antimicrobial Compounds in the Brown Film of Lentinula edodes Mycelium via LC-MS/MS Analysis.

Lihua Tang, Junjun Shang, Chunyan Song, Ruiheng Yang, Xiaodong Shang, Wenjun Mao, Dapeng Bao, Qi Tan,

The brown film (BF) of Lentinula edodes mycelium has been reported to exert biological activities during mushroom cultivation; however, to date, there is limited information on its chemical composition. In this study, untargeted metabolomics analysis was performed via liquid chromatography-mass spectrometry (LC-MS), and the results were used to screen the ... Read more >>

ACS Omega (ACS omega)
[2020, 5(13):7567-7575]

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Capture of high energy orbit of Duffing oscillator with time-varying parameters.

Liuding Yu, Lihua Tang, Liuyang Xiong, Tiejun Yang,

This work investigates the time response of a Duffing oscillator with time-varying parameters (excitation frequency, linear stiffness, and mass) by approximate analytical and numerical methods. When the excitation frequency sweep covers the multisolution range, the characteristics of the response (maximum response, jump-up frequency, and jump-down frequency) mainly depend on the ... Read more >>

Chaos (Chaos (Woodbury, N.Y.))
[2020, 30(2):023106]

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First Report of Trunk Canker and Gummosis of Kumquat Caused by Lasiodiplodia theobromae in China

Qing Gui, Tangxun Guo, Tom Hsiang, Suiping Huang, Qili Li, Jianyou Mo, Wenxiu Sun, Lihua Tang, Zhihe Yu, Jiang Zhao,

Kumquat (Fortunella margarita [Lour.] Swingle) is widely cultivated in southern China. In June 2016, trunk cankers and gummosis were observed in four kumquat orchards in Yangshuo County, Guangxi Province, China, with an average of 10% disease incidence (DI) and a maximum of 30% DI in nearby locations. Initially, small brown ... Read more >>

Plant Dis. (Plant disease)
[2020, 104(3):971]

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Identification and Characterization of Pestalotioid Fungi Causing Leaf Spots on Mango in Southern China.

Juan Shu, Zhihe Yu, Wenxiu Sun, Jiang Zhao, Qili Li, Lihua Tang, Tangxun Guo, Suiping Huang, Jianyou Mo, Tom Hsiang, Shuming Luo,

Mango is an economically important fruit crop in southern China. However, leaf spots restrict the development of mango trees, reducing the yield and production. Pestalotioid fungi are one of the major agents causing leaf spots on mango. During 2016 and 2017, 21 isolates of pestalotioid fungi associated with leaf spots ... Read more >>

Plant Dis. (Plant disease)
[2020, 104(4):1207-1213]

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Agrobacterium-mediated transformation of arthroconidia obtained from the edible mushroom Hypsizygus marmoreus.

Dapeng Bao, Zhiheng Huang, Yan Li, Chenli Zhou, Yan Li, Jianing Wan, Lihua Tang, Wenjun Mao, Ying Wang, Ming Gong, Gen Zou, Yoichi Honda, Ruiheng Yang, Junjun Shang,

Using the carboxin resistance gene from Pleurotus eryngii as a selective marker, we introduced foreign DNA into the arthroconidia of Hypsizygus marmoreus through Agrobacterium-mediated transformation. The function of the exogenous GUS (β-glucuronidase) gene driven by the CaMV35S promoter was detected in the transformants. ... Read more >>

J. Microbiol. Methods (Journal of microbiological methods)
[2020, 171:105878]

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Intra-articular injection of indomethacin-methotrexate in situ hydrogel for the synergistic treatment of rheumatoid arthritis.

Na Yin, Xueting Guo, Rong Sun, Hongbing Liu, Lihua Tang, Jingxin Gou, Tian Yin, Haibing He, Yu Zhang, Xing Tang,

Rheumatoid arthritis is a chronic systemic autoimmune disease that causes joint swelling and cartilage damage. The objective of the present work was to develop a temperature-sensitive hydrogel (D-NGel) containing nanoparticles (D-NPs), which could simultaneously deliver combination indomethacin and methotrexate. D-NPs were formed by multiple non-covalent interactions between PEI-SS and the ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2020, 8(5):993-1007]

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In vitro antifungal activity of dimethyl trisulfide against Colletotrichum gloeosporioides from mango

Lihua Tang, Jianyou Mo, Tangxun Guo, Suiping Huang, Qili Li, Ping Ning, Tom Hsiang,

Colletotrichum gloeosporioides, one of the main agents of mango anthracnose, causes latent infections in unripe mango, and leads to huge economic losses during storage and transport. Dimethyl trisulfide (DMTS), one of the main volatile compounds produced by some microorganisms or plants, has shown antifungal activity against some phytopathogens in previous ... Read more >>

World J. Microbiol. Biotechnol. (World journal of microbiology & biotechnology.)
[2020, 36(1):4]

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In vitro antifungal activity of dimethyl trisulfide against Colletotrichum gloeosporioides from mango.

Lihua Tang, Jianyou Mo, Tangxun Guo, Suiping Huang, Qili Li, Ping Ning, Tom Hsiang,

Colletotrichum gloeosporioides, one of the main agents of mango anthracnose, causes latent infections in unripe mango, and leads to huge economic losses during storage and transport. Dimethyl trisulfide (DMTS), one of the main volatile compounds produced by some microorganisms or plants, has shown antifungal activity against some phytopathogens in previous ... Read more >>

World J. Microbiol. Biotechnol. (World journal of microbiology & biotechnology)
[2019, 36(1):4]

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First Report of Stem Canker and Dieback Caused by Neofusicoccum parvum on Plum in Guangxi, Southern China

Qili Li, Minzhong Fan, Tangxun Guo, Tom Hsiang, Suiping Huang, Jianyou Mo, Wenxiu Sun, Lihua Tang, Zongbin Zhang,

Plum (Prunus salicina L.) is a deciduous fruit tree native to China and widely distributed in this country. In 2017, extensive rainfall and favorable temperatures in June increased disease development, and subsequently a serious stem canker and dieback disease was observed in 3-year-old plums in Jinxiu (N24°20′, E110°07′), Guangxi province ... Read more >>

Plant Dis. (Plant disease)
[2019, 103(11):2952]

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Characterization and application of a gall midge resistance gene (Gm6) from Oryza sativa 'Kangwenqingzhan'.

Yang Li, Yi Mo, Zhihua Li, Meng Yang, Lihua Tang, Ling Cheng, Yongfu Qiu,

KEY MESSAGE:The resistance gene Gm6 was mapped and characterized using near-isogenic and pyramided lines, followed by marker-assisted selection to develop lines with resistance to both gall midge and brown planthopper. The Asian rice gall midge (GM; Orseolia oryzae; Diptera: Cecidomyiidae) is a major destructive pest affecting rice cultivation regions. The ... Read more >>

Theor. Appl. Genet. (TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik)
[2020, 133(2):579-591]

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Colletotrichum species associated with mango in southern China.

Qili Li, Junyan Bu, Juan Shu, Zhihe Yu, Lihua Tang, Suiping Huang, Tangxun Guo, Jianyou Mo, Shuming Luo, Ghulam Sarwar Solangi, Tom Hsiang,

Mango (Mangifera indica L.) is an economically significant fruit crop in provinces of southern China including Hainan, Yunnan, Sichuan, Guizhou, Guangdong and Fujian. The objective of this study was to examine the diversity of Colletotrichum species infecting mango cultivars in major growing areas in China, using morphological and molecular techniques ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):18891]

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Differential expression of two gpd genes in the cultivated mushroom Pleurotus eryngii using RNA sequencing analysis

Junjun Shang, Dapeng Bao, Ming Gong, Yoichi Honda, Yan Li, Yán Li, Wenjun Mao, Lihua Tang, Ying Wang, Ruiheng Yang,

Transcriptional analysis showed that Pegpd1 was constitutively and highly expressed in various developmental stages of P. eryngii. The expression level of Pegpd2 was much lower than Pegpd1. The promoter of Pegpd1 contained the conserved cis-regulatory elements and could be used to drive heterologous gene expression in genetic transformation of P. ... Read more >>

Mycoscience (Mycoscience)
[2019, 60(6):351-353]

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Development of a biological signal-based evaluator for robot-assisted upper-limb rehabilitation: a pilot study.

Bo Sheng, Lihua Tang, Oscar Moroni Moosman, Chao Deng, Shane Xie, Yanxin Zhang,

Bio-signal based assessment for upper-limb functions is an attractive technology for rehabilitation. In this work, an upper-limb function evaluator is developed based on biological signals, which could be used for selecting different robotic training protocols. Interaction force (IF) and participation level (PL, processed surface electromyography (sEMG) signals) are used as ... Read more >>

Australas Phys Eng Sci Med (Australasian physical & engineering sciences in medicine)
[2019, 42(3):789-801]

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Identification of Knee Osteoarthritis Based on Bayesian Network: Pilot Study.

Bo Sheng, Liang Huang, Xiangbin Wang, Jie Zhuang, Lihua Tang, Chao Deng, Yanxin Zhang,

BACKGROUND:Early identification of knee osteoarthritis (OA) can improve treatment outcomes and reduce medical costs. However, there are major limitations among existing classification or prediction models, including abstract data processing and complicated dataset attributes, which hinder their applications in clinical practice. OBJECTIVE:The aim of this study was to propose a Bayesian ... Read more >>

JMIR Med Inform (JMIR medical informatics)
[2019, 7(3):e13562]

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Antifungal effects of dimethyl trisulfide against Colletotrichum gloeosporioides infection on mango

Lihua Tang, Jianyou Mo, Tangxun Guo, Suiping Huang, Qili Li, Ping Ning, Tom Hsiang,

Colletotrichum gloeosporioides, one of the main agents of mango anthracnose, causes latent infections in unripe mango and can lead to huge losses during fruit storage and transport. Dimethyl trisulfide (DMTS) is an antifungal agent produced by several microorganisms or plants, but its effects on the infection process of C. gloeosporioides ... Read more >>

(Journal of Phytopathology (1986))
[2019, 167(7-8):445-450]

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Alterations in muscle activation patterns during robot-assisted bilateral training: A pilot study.

Bo Sheng, Lihua Tang, Shengquan Xie, Chao Deng, Yanxin Zhang,

Robot-assisted bilateral training is being developed as a new rehabilitation approach for stroke patients. However, there is still a lack of understanding of muscle functions when performing robot-assisted synchronous movements. The aim of this work is to explore the muscle activation patterns and the voluntary effort of participants during different ... Read more >>

Proc Inst Mech Eng H (Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine)
[2019, 233(2):219-231]

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Photoelectrochemical determination of the activity of protein kinase A by using g-C3N4 and CdS quantum dots.

Chengji Sui, Fei Liu, Lihua Tang, Xue Li, Yunlei Zhou, Huanshun Yin, Shiyun Ai,

A sensitive and selective photoelectrochemical (PEC) method is described for the detection of protein kinase A (PKA) activity based on the use of graphite-like carbon nitride (g-C3N4) and the CdS quantum dots (QDs). Firstly, a complex was synthesized from g-C3N4 and gold nanoparticles (AuNPs). It was employed as both the ... Read more >>

Mikrochim Acta (Mikrochimica acta)
[2018, 185(12):541]

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Enhanced cytotoxicity and apoptosis through inhibiting autophagy in metastatic potential colon cancer SW620 cells treated with Chlorin e6 photodynamic therapy.

Kaizhen Yang, Ting Niu, Mengyu Luo, Lihua Tang, Ling Kang,

Photodynamic therapy (PDT) is a novel and non-invasive treatment that induces apoptosis and autophagy. Autophagy could play a pro-survival role, thus inhibiting autophagic activity might be a promising method to enhance the effectiveness of PDT for tumors. In the present study, photosensitizer Chlorin e6 (Ce6) was found to mainly locate ... Read more >>

Photodiagnosis Photodyn Ther (Photodiagnosis and photodynamic therapy)
[2018, 24:332-341]

Cited: 1 time

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Efficient transformation of Pleurotus eryngii with a safe selective marker mutated from the Pesdi1 gene.

Junjun Shang, Yan Li, Ruiheng Yang, Ying Wang, Wenjun Mao, Lihua Tang, Yingying Wu, Takehito Nakazawa, Yoichi Honda, Yan Li, Dapeng Bao,

We introduced a site-directed mutation in the sdi1 gene and used it as a selective marker for the polyethylene glycol-mediated transformation of Pleurotus eryngii monokaryon protoplasts. The transformants displayed obvious and stable resistance to the fungicide carboxin indicating that the mutant Pesdi1 gene is an efficient selective marker. ... Read more >>

J. Microbiol. Methods (Journal of microbiological methods)
[2018, 152:7-9]

Cited: 1 time

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Identification and Characterization of Colletotrichum Species Associated with Mango Anthracnose in Guangxi, China

Jianyou Mo, Ghulam S. Solangi, Guang Zhao, Lihua Tang, Qili Li, Suiping Huang, Tangxun Guo, Tom Hsiang,

Mango (Mangifera indica) is widely grown across southern China, especially in the provinces of Guangxi, Hainan, Yunnan, Sichuan, and Taiwan. Guangxi itself has over 86,667 ha of mango production. The purpose of this study was to identify Colletotrichum species associated with mango in different parts of Guangxi and examine their ... Read more >>

(Plant disease.)
[2018, 102(7):1283-1289]

Cited: 1 time

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Draft Genome Sequence of an Isolate of Colletotrichum fructicola, a Causal Agent of Mango Anthracnose.

Qili Li, Junyan Bu, Zhihe Yu, Lihua Tang, Suiping Huang, Tangxun Guo, Jianyou Mo, Tom Hsiang,

Here, we present a draft genome sequence of isolate 15060 of Colletotrichum fructicola, a causal agent of mango anthracnose. The final assembly consists of 1,048 scaffolds totaling 56,493,063 bp (G+C content, 53.38%) and 15,180 predicted genes. ... Read more >>

Genome Announc (Genome announcements)
[2018, 6(8):]

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Identification and Characterization of Colletotrichum Species Associated with Mango Anthracnose in Guangxi, China.

Jianyou Mo, Guang Zhao, Qili Li, Ghulam S Solangi, Lihua Tang, Tangxun Guo, Suiping Huang, Tom Hsiang,

Mango (Mangifera indica) is widely grown across southern China, especially in the provinces of Guangxi, Hainan, Yunnan, Sichuan, and Taiwan. Guangxi itself has over 86,667 ha of mango production. The purpose of this study was to identify Colletotrichum species associated with mango in different parts of Guangxi and examine their ... Read more >>

Plant Dis. (Plant disease)
[2018, 102(7):1283-1289]

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LASP1 promotes nasopharyngeal carcinoma progression through negatively regulation of the tumor suppressor PTEN.

Qingzu Gao, Lihua Tang, Ling Wu, Kaitao Li, Hui Wang, Weidong Li, Juan Wu, Mingyi Li, Shuang Wang, Liang Zhao,

LIM and SH3 protein 1 (LASP1) enhances tumor growth and metastasis in various cancers, but its role in nasopharyngeal carcinoma (NPC) remains unclear. Herein, we investigated the role of LASP1 in NPC and explored the underlying mechanisms in NPC. Clinically, overexpression of LASP1 is associated with tumor metastasis and poor ... Read more >>

Cell Death Dis (Cell death & disease)
[2018, 9(3):393]

Cited: 5 times

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Evaluation of the effect of dabrafenib and metabolites on QTc interval in patients with BRAF V600-mutant tumours.

Noelia Nebot, Hendrik-Tobias Arkenau, Jeffrey R Infante, Jason C Chandler, Andrew Weickhardt, Jason D Lickliter, John Sarantopoulos, Michael S Gordon, Gabriel Mak, Annie St-Pierre, Lihua Tang, Bijoyesh Mookerjee, Stanley W Carson, Siobhan Hayes, Kenneth F Grossmann,

AIMS:The effect of repeat oral supratherapeutic dosing of the BRAF inhibitor dabrafenib on QTc interval was assessed in patients with BRAF V600-mutant tumours. METHODS:Part 1 of this phase 1, multicentre, 2-part study (BRF113773/NCT01738451) assessed safety/tolerability of dabrafenib 225 or 300 mg twice daily (BID) to inform part 2 dosing. Patients in ... Read more >>

Br J Clin Pharmacol (British journal of clinical pharmacology)
[2018, 84(4):764-775]

Cited: 2 times

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