Full Text Journal Articles by
Author Li Meng

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Leaf extract from Vitis vinifera L. reduces high fat diet-induced obesity in mice.

Li Meng, Yuehua Jiao, Xiaohong Zhou, Cong Liang, Kexin Yan, Ye Zhao, Xiujie Deng, Xue Han, Yanyan Yang, Hanmin Liu, Pimin Gong, Lanwei Zhang,

Despite the health benefits of Vitis vinifera L. leaves, its anti-obesity potential has not been fully explored. In this work, we showed that Vitis vinifera L. leaf extract (VLE) inhibits the pancreatic lipase activity. Intragastric administration of VLE to mice led to a significant decrease in the body weight, tissue ... Read more >>

Food Funct (Food & function)
[2021, 12(14):6452-6463]

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Study on mechanism of matrine in treatment of COVID-19 combined with liver injury by network pharmacology and molecular docking technology.

Fangzhou Liu, Yuanbai Li, Yang Yang, Meng Li, Yu Du, Yiying Zhang, Jing Wang, Yujing Shi,

The aim of the present study was to investigate the pharmacological mechanism of matrine in treatment of COVID-19 combined with liver injury. Potential targets related to matrine, COVID-19 and liver injury were identified from several databases. We constructed PPI network and screened the core targets according to the degree value. ... Read more >>

Drug Deliv (Drug delivery)
[2021, 28(1):325-342]

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Development and in vivo evaluation of intranasal formulations of parathyroid hormone (1-34).

Dan Wang, Yimeng Du, Wenpeng Zhang, Xiaolu Han, Hui Zhang, Zengming Wang, Nan Liu, Meng Li, Xiang Gao, Xiaomei Zhuang, Jing Gao, Aiping Zheng,

For efficient intranasal transport of parathyroid hormone (1-34) [PTH(1-34)], there is a great medical need to investigate permeation enhancers for intranasal formulations. In this study, the development of PTH(1-34) intranasal formulations was conducted. Based on conformation and chemical stability studies, the most preferable aqueous environment was determined to be 0.008 M ... Read more >>

Drug Deliv (Drug delivery)
[2021, 28(1):487-498]

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MicroRNA-29b/29c targeting CTRP6 influences porcine adipogenesis via the AKT/PKA/MAPK Signalling pathway.

Wenjing Wu, Ke Xu, Meng Li, Jin Zhang, Yizhen Wang,

Porcine fat deposition is an important economic trait of pig breeds, and understanding the gene regulatory network in adipocytes is essential for modern pig breeding. In a previous study, we demonstrated that miR-29a negatively regulates the differentiation of porcine adipocytes. In this study, we investigated the roles of miR-29b/c in ... Read more >>

Adipocyte (Adipocyte)
[2021, 10(1):264-274]

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Flavor principle as an implicit frame: Its effect on the acceptance of instant noodles in a cross-cultural context

Meng Li, Seo-Jin Chung,

This study investigated how the stability of liking ratings for instant noodles can be affected by implicit frames of reference constructed by flavor principles, unique combinations of flavor ingredients that can be identified as characterizing a particular ethnic/cultural cuisine, in a cross-cultural context. The influence of consumers’ food neophobia on ... Read more >>

(Food quality and preference.)
[2021, 93:Not Available]

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Neuronal activity-induced SUMOylation of Akt1 by PIAS3 is required for long-term potentiation of synaptic transmission.

Li Meng, Cai-Ping Du, Chun-Yuan Lu, Kun Zhang, Lin Li, Jing-Zhi Yan, Xiao-Yu Hou,

Neuronal activity regulates spatial distribution of the SUMOylation system in cytosolic and dendritic sites, which has been implicated in learning, memory, and underlying synaptic structural and functional remodeling in the hippocampus. However, the functional target proteins for activated small ubiquitin-like modifiers (SUMOs) and downstream molecular consequences behind long-term potentiation (LTP) ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2021, 35(8):e21769]

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Enhanced electrochemical reduction of CO2 to CO on Ag/SnO2 by synergistic effect of morphology and structural defects.

Dongsheng Geng, Meng Li, Yue Hu, Dawei Wang,

Silver (Ag) based materials are considered to be promising materials for electrochemical reduction of CO2 to produce CO, but the selectivity and efficiency of traditional polycrystalline Ag materials is insufficient, where still exists a great challenge to explore novel modified Ag based materials. Herein, a nanocomposite of Ag and SnO2 ... Read more >>

Chem Asian J (Chemistry, an Asian journal)
[2021, :]

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Prenatal Exposure to Solar Radiation and Hypertensive Disorders of Pregnancy.

Danni Lu, Meng Li, Yuexin Gan, Guoqi Yu, Qianlong Zhang, Jun Zhang,

<h4>Objective</h4>To examine the association between prenatal exposure to solar radiation and hypertensive disorders of pregnancy (HDP).<h4>Design</h4>A multicenter retrospective study.<h4>Setting</h4>19 hospitals in the U.S.<h4>Population</h4>205,888 women with singleton gestation from the Consortium on Safe Labor (2002- 2008).<h4>Main outcome measures</h4>Gestational hypertension, preeclampsia/eclampsia, and preeclampsia superimposed on chronic hypertension.<h4>Methods</h4>Medical records of the participants were ... Read more >>

BJOG (BJOG : an international journal of obstetrics and gynaecology)
[2021, :]

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Association between perceived birth trauma and postpartum depression: A prospective cohort study in China.

Yanfang Chen, Faeeha Ismail, Ziyu Xiong, Meng Li, Innie Chen, Shi Wu Wen, Ri-Hua Xie,

<h4>Objective</h4>To assess the association between women's perceived birth trauma and risk of postpartum depression (PPD).<h4>Methods</h4>We conducted a prospective cohort study in China between December 2018 and November 2019. Women aged 18-45 years who gave a singleton live birth at a university teaching hospital were enrolled after written consent was obtained. ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, :]

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Solution-Synthesized SnSe1-xSx: Dual-Functional Materials with Enhanced Electrochemical Storage and Thermoelectric Performance.

Hong Zhang, Xiaofang Liu, Jiacheng Wang, Bin Zhang, Jie Chen, Lei Yang, Guoyu Wang, Meng Li, Yujie Zheng, Xiaoyuan Zhou, Guang Han,

The exploration of materials with multifunctional properties, such as energy harvesting and storage, is crucial in integrated energy devices and technologies. Herein, through an organic-free "soft chemical" solution method, a series of dual-functional SnSe<sub>1-<i>x</i></sub>S<sub><i>x</i></sub> (<i>x</i> = 0, 0.1, 0.2, 0.3, 0.4, and 0.5) nanoparticles have been developed toward high-performance electrochemical ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, :]

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Efficacy and safety of Zi Gui Nv Zhen® capsules used in TCM for fertility preservation in patients with diminished ovarian reserve.

Zhongting Xu, Xiangyan Ruan, Xin Xu, Yu Yang, Jiaojiao Cheng, Suiyu Luo, Min Min, Meng Li, Luping Zhang, Rui Ju, Fengyu Jin, Alfred Otto Mueck,

<h4>Objective</h4>To evaluate for the first time whether Zi Gui Nv Zhen<sup>®</sup> capsules (ZGNZC), until now used in traditional Chinese medicine (TCM) for menopausal complaints, can increase the fertility of Chinese women with diminished ovarian reserve (DOR).<h4>Methods</h4>Prospective, randomized, open-labeled 3-monthly study; 109 DOR patients (aged 20-40 years) receiving either ZGNZC (experimental group, ... Read more >>

Gynecol Endocrinol (Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology)
[2021, :1-5]

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Neuron navigator 2 is a novel mediator of rheumatoid arthritis.

Ran Wang, Meng Li, Qian Ding, Jianghong Cai, Yue Yu, Xinhua Liu, Jianchun Mao, Yi Zhun Zhu,

Cell Mol Immunol (Cellular & molecular immunology)
[2021, :]

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Fabrication of magnetic dual-hydrophilic metal organic framework for highly efficient glycopeptide enrichment.

Ping Su, Zhen Wang, Xin Li, Meng Li, Gao Li, Zhen Gong, Jiayi Song, Yi Yang,

Highly selective glycopeptide enrichment is important before mass spectrometry analysis because of the ultra-low abundance of glycopeptides in the peptide mixtures. Herein, a UiO-66-NH<sub>2</sub>-based magnetic composite was prepared and used for the hydrophilic enrichment of glycopeptides. The composite was modified with phytic acid (PA) molecules by partially replacing 2-aminoterephthalic acid ... Read more >>

Anal Bioanal Chem (Analytical and bioanalytical chemistry)
[2021, :]

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Population pharmacokinetic analysis of dupilumab in adult and adolescent patients with asthma.

Li Zhang, Yue Gao, Meng Li, Christine Xu, John D Davis, Vanaja Kanamaluru, Qiang Lu,

A population pharmacokinetic model was developed using data from healthy subjects and patients with moderate-to-severe asthma receiving intravenous or subcutaneous dupilumab doses. A total of nine phase I to phase III studies were pooled (202 healthy subjects and 1912 patients with asthma including 68 adolescents) in the model development. The ... Read more >>

CPT Pharmacometrics Syst Pharmacol (CPT: pharmacometrics & systems pharmacology)
[2021, :]

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Side Area-Assisted 3D Evaporator with Antibiofouling Function for Ultra-Efficient Solar Steam Generation.

Haoxuan Li, Wei Zhu, Meng Li, Ying Li, Ryan T K Kwok, Jacky W Y Lam, Lei Wang, Dong Wang, Ben Zhong Tang,

Solar-driven interfacial steam generation (SISG) has been recognized as a promising strategy to solve water shortages in an eco-friendly and low-cost way. However, the practical application of SISG is vitally restricted by some inherent limits, especially for finite evaporation rate and insufficient working life of evaporator. Herein, a novel SISG ... Read more >>

Adv Mater (Advanced materials (Deerfield Beach, Fla.))
[2021, :e2102258]

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Hepatic mitochondrial SAB deletion or knockdown alleviates diet induced metabolic syndrome, steatohepatitis and hepatic fibrosis.

Sanda Win, Robert W M Min, Jun Zhang, Gary Kanel, Brad Wanken, Yibu Chen, Meng Li, Ying Wang, Ayako Suzuki, Filbert W M Aung, Susan F Murray, Mariam Aghajan, Tin A Than, Neil Kaplowitz,

The hepatic MAPK cascade leading to JNK activation has been implicated in the pathogenesis of nonalcoholic fatty liver /non-alcoholic steatohepatitis (NAFL/NASH). In acute hepatotoxicity we previously identified a pivotal role for mitochondrial SH3BP5 (SAB) as a target of JNK which sustains its activation through promotion of reactive oxygen species (ROS) ... Read more >>

Hepatology (Hepatology (Baltimore, Md.))
[2021, :]

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A novel multiple subdivision-based algorithm for quantitative assessment of retinal vascular tortuosity.

Gengyuan Wang, Meng Li, Zhaoqiang Yun, Zhengyu Duan, Ke Ma, Zhongzhou Luo, Peng Xiao, Jin Yuan,

Vascular tortuosity as an indicator of retinal vascular morphological changes can be quantitatively analyzed and used as a biomarker for the early diagnosis of relevant disease such as diabetes. While various methods have been proposed to evaluate retinal vascular tortuosity, the main obstacle limiting their clinical application is the poor ... Read more >>

Exp Biol Med (Maywood) (Experimental biology and medicine (Maywood, N.J.))
[2021, :15353702211032898]

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High-Efficiency Circularly Polarized Electroluminescence from TADF-Sensitized Fluorescent Enantiomers.

Chuan-Feng Chen, Meng Li, Mei-Ying Wang, Yin-Feng Wang, Liheng Feng,

A couple of fluorescent enantiomers, which are suitable for the emitters of high-efficiency TADF-sensitized CP-OLEDs, have been developed. The enantiomers show configurational stability, high PLQY of 98%, large k r of 7.8×10 7 s -1 , and intense CPL activities with |g lum | values of about 2.5 × 10 ... Read more >>

Angew Chem Int Ed Engl (Angewandte Chemie (International ed. in English))
[2021, :]

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Quantitative Förster Resonance Energy Transfer: Efficient Light Harvesting for Sequential Photo-Thermo-Electric Conversion.

Kuo Fu, Xiaoxuan Zeng, Xinpeng Zhao, Yue Wu, Meng Li, Xin-Shun Li, Chengjun Pan, Zhijun Chen, Zhen-Qiang Yu,

Light is essential to all life on the earth. Thus, highly efficient light-harvesting systems with the sequential energy transfer process are significant for using solar energy in photosynthesis. For developing an efficient light-harvesting system, a liquid aggregation-induced emission (AIE) dye TPE-EA is obtained, as a donor and solvent, which can ... Read more >>

Small (Small (Weinheim an der Bergstrasse, Germany))
[2021, :e2103172]

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Direct comparison of two kinds of linoleic acid-docetaxel derivatives: in vitro cytotoxicity and in vivo antitumor activity.

Lirui Jia, Ying Liu, Meng Li, Yongjun Wang, Zhonggui He,

Rational designed lipid-drug derivatives provide a favorable approach to improve the druggability of highly hydrophobic prototypes. It has been regarded as common sense that good cytotoxicity is the guarantee of superior anticancer efficacy for candidate derivatives screening. However, does it apply to lipid-drug conjugate-based self-assembled nanoparticles? Here, we established the ... Read more >>

Drug Deliv Transl Res (Drug delivery and translational research)
[2021, :]

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Retinal vascular geometry detection as a biomarker in diabetes mellitus.

Meng Li, Gengyuan Wang, Honghui Xia, Ziqing Feng, Peng Xiao, Jin Yuan,

<h4>Objective</h4>To compare the vessel geometry characteristics of color fundus photographs in normal control and diabetes mellitus (DM) patients and to find potential biomarkers for early diabetic retinopathy (DR) based on a neural network vessel segmentation system and automated vascular geometry parameter analysis software.<h4>Methods</h4>A total of 102 consecutive patients with type ... Read more >>

Eur J Ophthalmol (European journal of ophthalmology)
[2021, :11206721211033488]

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Palladium-catalyzed selective oxidative amination of olefins with Lewis basic amines

Yangbin Jin, Chunsheng Li, Meng Li, Wanqing Wu, Huanfeng Jiang,

Amines are prominent in natural products, pharmaceutical agents, and agrochemicals. Moreover, they are synthetically valuable building blocks for the construction of complex organic molecules and functional materials. However, amines, especially aliphatic and aromatic amines with free N-H, are prone to coordinate with transition-metal and deactivating the catalyst, posing a tremendous ... Read more >>

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Ligilactobacillus Salivarius LCK11 Prevents Obesity by Promoting PYY Secretion to Inhibit Appetite and Regulating Gut Microbiota in C57BL/6J Mice.

Cong Liang, Xiao-Hong Zhou, Yue-Hua Jiao, Mei-Jie Guo, Li Meng, Pi-Min Gong, Lin-Zheng Lyu, Hai-Yue Niu, Yi-Fan Wu, Shi-Wei Chen, Xue Han, Lan-Wei Zhang,

<h4>Scope</h4>Obesity is a common disease worldwide and there is an urgent need for strategies to preventing obesity.<h4>Methods and results</h4>The anti-obesity effect and mechanism of Ligilactobacillus salivarius LCK11 (LCK11) is studied using a C57BL/6J male mouse model in which obesity is induced by a high-fat diet (HFD). Results show that LCK11 ... Read more >>

Mol Nutr Food Res (Molecular nutrition & food research)
[2021, :e2100136]

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Policy Interventions, Development Trends, and Service Innovations of Internet Hospitals in China: Documentary Analysis and Qualitative Interview Study.

Yunfeng Lai, Shengqi Chen, Meng Li, Carolina Oi Lam Ung, Hao Hu,

<h4>Background</h4>Internet hospitals have been encouraged by the Chinese government to develop an innovative medical service model that mainly uses new internet-based technologies to increase access to health care and improve the quality and efficiency of health care delivery. However, the academic exploration of the institutional and sectoral development of internet ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2021, 23(7):e22330]

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The long noncoding RNA HOTAIRM1 controlled by AML1 enhances glucocorticoid resistance by activating RHOA/ROCK1 pathway through suppressing ARHGAP18.

Liang Liang, Wenbin Gu, Meng Li, Ran Gao, Xin Zhang, Chongye Guo, Shuangli Mi,

Acquired resistance to glucocorticoids (GCs) is an obstacle to the effective treatment of leukemia, but the molecular mechanisms of steroid insensitivity have not been fully elucidated. In this study, we established an acquired GC-resistant leukemia cell model and found a long noncoding RNA, HOTAIRM1, was overexpressed in the resistant cells ... Read more >>

Cell Death Dis (Cell death & disease)
[2021, 12(7):702]

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