Full Text Journal Articles by
Author Leslie H Lundahl

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N-acetylcysteine reduces cocaine-seeking behavior and anterior cingulate glutamate/glutamine levels among cocaine-dependent individuals.

Eric A Woodcock, Leslie H Lundahl, Dalal Khatib, Jeffrey A Stanley, Mark K Greenwald,

N-acetylcysteine (NAC) is a cystine prodrug shown to reduce cocaine- and cue-primed reinstatement of cocaine-seeking behavior in preclinical studies. In this inpatient study, the effects of NAC maintenance versus placebo on cocaine-seeking behavior were examined during cocaine-primed and unprimed self-administration sessions among non-treatment-seeking, cocaine-dependent individuals. Twelve participants completed this double-blind, ... Read more >>

Addict Biol (Addiction biology)
[2020, :e12900]

Cited: 0 times

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Focus on Adolescent Use of Club Drugs and "Other" Substances.

Janet F Williams, Leslie H Lundahl,

Club drugs and "other" abusable substances are briefly overviewed as a reminder about the wide variety of known and unknown substances used by adolescents, the high potential for direct and interactive substance use effects to manifest acutely and chronically, and the vigilance needed to anticipate and recognize the new effects ... Read more >>

Pediatr Clin North Am (Pediatric clinics of North America)
[2019, 66(6):1121-1134]

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Adolescent Substance Abuse and Treatment: A Primer for Clinicians.

Leslie H Lundahl, David R Rosenberg,

Pediatr Clin North Am (Pediatric clinics of North America)
[2019, 66(6):xvii-xix]

Cited: 0 times

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Beyond the Bud: Emerging Methods of Cannabis Consumption for Youth.

Cara A Struble, Jennifer D Ellis, Leslie H Lundahl,

Cannabis continues to be the most widely used illicit substance among youth, as many teens view the risks of cannabis consumption to be low. With cannabis laws becoming lax and dispensaries becoming more prevalent throughout the United States, highly concentrated Δ-9-tetrahydrocannibinol (THC) is becoming readily available. This article examines the ... Read more >>

Pediatr Clin North Am (Pediatric clinics of North America)
[2019, 66(6):1087-1097]

Cited: 0 times

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Demographic, Cannabis Use, and Depressive Correlates of Cannabis Use Consequences in Regular Cannabis Users.

Cara A Struble, Jennifer D Ellis, Molly Cairncross, Jamey J Lister, Leslie H Lundahl,

BACKGROUND AND OBJECTIVES:Regular cannabis users experience cannabis-related consequences across many domains of functioning. The present study examined demographic, cannabis use, and depressive correlates of cannabis consequences. We hypothesized that (1) earlier onset of use would predict greater psychological and functional consequences; and (2) women would endorse more psychological and withdrawal ... Read more >>

Am J Addict (The American journal on addictions)
[2019, 28(4):295-302]

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Correlates of Treatment Retention and Opioid Misuse Among Postpartum Women in Methadone Treatment.

Jennifer D Ellis, Molly Cairncross, Cara A Struble, Meagan M Carr, David M Ledgerwood, Leslie H Lundahl,

OBJECTIVES:The postpartum period is a particularly challenging time for women in methadone treatment. Unfortunately, this is also the time when women are vulnerable to treatment discontinuation and opioid misuse. The purpose of the present exploratory study was to examine demographic, treatment, and delivery factors that may be associated with postbirth ... Read more >>

J Addict Med (Journal of addiction medicine)
[2019, 13(2):153-158]

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Which Problem Are We Addressing Today? The Utility of a Multifaceted Formulation Approach to a Complex Case.

Anita Kumar Chang, Leslie H Lundahl,

A case of a 54-year-old woman with posttraumatic stress disorder, somatic delusions, and borderline personality disorder is presented by using psychodynamic, trauma-informed, and cognitive-behavioral formulations. The usefulness of a multifaceted formulation in the treatment of the case is discussed along with a review of relevant literature. ... Read more >>

Am J Psychother (American journal of psychotherapy)
[2019, 72(1):29-33]

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Characteristics and Triage of Children Presenting in Mental Health Crisis to Emergency Departments at Detroit Regional Hospitals.

Kristen Williams, Amanda R Levine, David M Ledgerwood, Alireza Amirsadri, Leslie H Lundahl,

The number of children in the United States utilizing emergency department (ED) services for psychiatric crises is increasing, and psychiatric-related ED visits disproportionately burden hospital resources. Yet, there is limited available information on the epidemiology and outcomes of pediatric mental health emergencies. The present study sought to characterize pediatric mental ... Read more >>

Pediatr Emerg Care (Pediatric emergency care)
[2018, 34(5):317-321]

Cited: 1 time

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Injection opioid use as a predictor of treatment outcomes among methadone-maintained opioid-dependent patients.

David M Ledgerwood, Jamey J Lister, Benjamin LaLiberte, Leslie H Lundahl, Mark K Greenwald,

BACKGROUND:Injection opioid use is associated with more severe health and psychosocial consequences relative to non-injection use, but few studies have examined whether injection use is associated with methadone maintenance treatment outcomes. The present study examined differential MMT outcomes among opioid injectors and non-injectors. METHODS:Data were extracted from the clinic charts ... Read more >>

Addict Behav (Addictive behaviors)
[2019, 90:191-195]

Cited: 2 times

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Factors associated with sedative use and misuse among heroin users.

Tabitha E H Moses, Leslie H Lundahl, Mark K Greenwald,

BACKGROUND:Rates of both opioid and sedative use and misuse are rising. Comorbid opioid and sedative use is associated with especially severe consequences (e.g., overdose and poor health outcomes). Heroin users report multiple motivations for sedative use, including self-medication. We aimed to understand differences in lifetime substance use characteristics between heroin ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2018, 185:10-16]

Cited: 3 times

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Mediational Pathways Among Trait Impulsivity, Heroin-use Consequences, and Current Mood State.

Holly H Reid, Leslie H Lundahl, Jamey J Lister, Eric A Woodcock, Mark K Greenwald,

Background:This study examined whether lifetime heroin-use consequences mediate the relationship between trait impulsivity and three current mood outcomes: depression symptoms, stress levels, and perception of life events. Method:Regular heroin users (N = 163) were assessed using the Barratt Impulsiveness Scale (BIS-11) to measure trait impulsivity; a standardized Drug History and ... Read more >>

Addict Res Theory (Addiction research & theory)
[2018, 26(5):421-429]

Cited: 0 times

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Developing a scale of domains of negative consequences of chronic heroin use.

Tabitha E H Moses, Eric A Woodcock, Jamey J Lister, Leslie H Lundahl, Mark K Greenwald,

BACKGROUND:Chronic use of heroin typically leads to numerous negative life consequences and serious clinical impairment. Increased negative consequences can result in poor treatment outcomes as well as adverse health effects and impaired social functioning. Certain risk factors, including early substance use initiation, concurrent use of other illicit substances, and injection ... Read more >>

Addict Behav (Addictive behaviors)
[2018, 77:260-266]

Cited: 3 times

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Magnitude and duration of cue-induced craving for marijuana in volunteers with cannabis use disorder.

Leslie H Lundahl, Mark K Greenwald,

AIMS:Evaluate magnitude and duration of subjective and physiologic responses to neutral and marijuana (MJ)-related cues in cannabis dependent volunteers. METHODS:33 volunteers (17 male) who met DSM-IV criteria for Cannabis Abuse or Dependence were exposed to neutral (first) then MJ-related visual, auditory, olfactory and tactile cues. Mood, drug craving and physiology ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2016, 166:143-149]

Cited: 3 times

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Heroin delay discounting: Modulation by pharmacological state, drug-use impulsivity, and intelligence.

Jonathan J K Stoltman, Eric A Woodcock, Jamey J Lister, Leslie H Lundahl, Mark K Greenwald,

Delay discounting (DD) refers to how rapidly an individual devalues goods based on delays to receipt. DD usually is considered a trait variable but can be state dependent, yet few studies have assessed commodity valuation at short, naturalistically relevant time intervals that might enable state-dependent analysis. This study aimed to ... Read more >>

Exp Clin Psychopharmacol (Experimental and clinical psychopharmacology)
[2015, 23(6):455-463]

Cited: 2 times

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Progression to regular heroin use: examination of patterns, predictors, and consequences.

Eric A Woodcock, Leslie H Lundahl, Jonathan J K Stoltman, Mark K Greenwald,

The present study retrospectively evaluated the chronology and predictors of substance use progression in current heroin-using individuals.Out-of-treatment heroin users (urinalysis-verified; N=562) were screened for laboratory-based research studies using questionnaires and urinalysis. Comprehensive substance use histories were collected. Between- and within-substance use progression was analyzed using stepwise linear regression models.The strongest ... Read more >>

Addict Behav (Addictive behaviors)
[2015, 45:287-293]

Cited: 13 times

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Functional mu opioid receptor polymorphism (OPRM1 A(118) G) associated with heroin use outcomes in Caucasian males: A pilot study.

Eric A Woodcock, Leslie H Lundahl, Margit Burmeister, Mark K Greenwald,

Heroin's analgesic, euphoric and dependence-producing effects are primarily mediated by the mu opioid receptor (MOR). A single gene, OPRM1, encodes the MOR. The functional polymorphism A(118)G, located in exon 1 of the OPRM1 gene, results in anatomically-specific reductions in MOR expression, which may alter an individual's response to heroin. In ... Read more >>

Am J Addict (The American journal on addictions)
[2015, 24(4):329-335]

Cited: 12 times

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Exploration of the telescoping effect among not-in-treatment, intensive heroin-using research volunteers.

Jonathan J K Stoltman, Eric A Woodcock, Jamey J Lister, Mark K Greenwald, Leslie H Lundahl,

Addiction research literature suggests some demographic groups exhibit a later age of substance use initiation, more rapid escalation to dependence, and worse substance use-related outcomes. This 'telescoping' effect has been observed more often in females but has not yet been examined in not-in-treatment heroin users or racial subgroups.Not-in-treatment, intensive heroin-using ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2015, 148:217-220]

Cited: 7 times

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Predictors of buprenorphine initial outpatient maintenance and dose taper response among non-treatment-seeking heroin dependent volunteers.

Eric A Woodcock, Leslie H Lundahl, Mark K Greenwald,

Buprenorphine (BUP) is effective for treating opioid use disorder. Individuals' heroin-use characteristics may predict their responses to BUP, which could differ during maintenance and dose-taper phases. If so, treatment providers could use pre-treatment characteristics to personalize level of individual care and possibly improve treatment outcomes.Non-treatment-seeking heroin-dependent volunteers (N=34) initiated outpatient ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2015, 146:89-96]

Cited: 4 times

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Effect of oral THC pretreatment on marijuana cue-induced responses in cannabis dependent volunteers.

Leslie H Lundahl, Mark K Greenwald,

BACKGROUND: The current study tested whether oral Δ(9)-tetrahydrocannabinol (THC: 0-, 10-, and 20-mg) pretreatment would attenuate polysensory cue-induced craving for marijuana. METHODS: Cannabis dependent participants (7 males and 7 females, who smoked on average 5.4 ± 1.1 blunts daily) completed 3 experimental sessions (oral THC pretreatment dose; counterbalanced order) using ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2015, 149:187-193]

Cited: 5 times

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Gender-specific predictors of retention and opioid abstinence during methadone maintenance treatment.

Amanda R Levine, Leslie H Lundahl, David M Ledgerwood, Michael Lisieski, Gary L Rhodes, Mark K Greenwald,

Retention in methadone maintenance treatment (MMT) for 1 year is associated with positive outcomes including opioid abstinence, however, most studies have not investigated gender differences. We hypothesized that predictors of retention and opioid abstinence would differ between men and women, and aimed to determine which factors best predict retention and ... Read more >>

J Subst Abuse Treat (Journal of substance abuse treatment)
[2015, 54:37-43]

Cited: 12 times

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Causal pathways between impulsiveness, cocaine use consequences, and depression.

Jamey J Lister, David M Ledgerwood, Leslie H Lundahl, Mark K Greenwald,

AIMS:The present study examined whether lifetime cocaine use consequences mediate the relationship between trait impulsiveness and current depression symptoms among regular cocaine users. METHODS:Regular cocaine users (N=108) were assessed using: Barratt Impulsiveness Scale subscales (non-planning, attentional, motor sub-scales) to measure trait impulsiveness; a standardized Drug History and Use Questionnaire to ... Read more >>

Addict Behav (Addictive behaviors)
[2015, 41:1-6]

Cited: 4 times

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Evolving array of substances used by adolescents.

Janet F Williams, Leslie H Lundahl, Rachel S D Fortune,

Adolesc Med State Art Rev (Adolescent medicine: state of the art reviews)
[2014, 25(1):184-214]

Cited: 0 times

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Impulsivity as a predictor of treatment outcome in substance use disorders: review and synthesis.

Amy M Loree, Leslie H Lundahl, David M Ledgerwood,

Impulsivity is a widely studied personality trait and research construct that has been implicated as a risk factor for substance use, including initiating and continuing use. However, relatively few studies have examined impulsivity as a predictor of treatment outcome. Because impulsivity has been operationalised in many different ways, cross-comparisons of ... Read more >>

Drug Alcohol Rev (Drug and alcohol review)
[2015, 34(2):119-134]

Cited: 34 times

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Effect of experimental analogs of contingency management treatment on cocaine seeking behavior.

Mark K Greenwald, David M Ledgerwood, Leslie H Lundahl, Caren L Steinmiller,

Contingency management (CM) treatment is effective for treating cocaine dependence but further mechanistic studies of its efficacy are warranted. This study aimed to determine whether: (a) higher vs. lower predictable money amounts ($3 vs. $1; analogs of standard voucher-based CM) increase cocaine demand elasticity; and (b) probabilistic amounts matched for ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2014, 139:164-168]

Cited: 5 times

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Cue-induced craving for marijuana in cannabis-dependent adults.

Leslie H Lundahl, Chris-Ellyn Johanson,

Recent interest in the development of medications for treatment of cannabis-use disorders indicates the need for laboratory models to evaluate potential compounds prior to undertaking clinical trials. To investigate whether a cue-reactivity paradigm could induce marijuana craving in cannabis-dependent adults, 16 (eight female) cannabis-dependent and 16 (eight female) cannabis-naïve participants ... Read more >>

Exp Clin Psychopharmacol (Experimental and clinical psychopharmacology)
[2011, 19(3):224-230]

Cited: 12 times

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