Full Text Journal Articles by
Author Laura Pina Camacho

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Trends in utilisation of hypnotics among Scandinavian young people.

Celso Arango, Laura Pina-Camacho,

Acta Psychiatr Scand (Acta psychiatrica Scandinavica)
[2021, 144(2):97-99]

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The effect of family environment and psychiatric family history on psychosocial functioning in first-episode psychosis at baseline and after 2 years.

Norma Verdolini, Silvia Amoretti, Gisela Mezquida, Manuel J Cuesta, Laura Pina-Camacho, Clemente García-Rizo, Antonio Lobo, Ana González-Pinto, Jessica Merchán-Naranjo, Iluminada Corripio, Estela Salagre, Immaculada Baeza, Daniel Bergé, Marina Garriga, Miquel Bioque, Catalina Vallespir, Maria Serra, Eduard Vieta, Miguel Bernardo,

The aim of the present study was to evaluate the contribution of family environment styles and psychiatric family history on functioning of patients presenting first-episode psychosis (FEP). Patients with FEP and healthy controls (HC) were assessed at baseline and after 2 years. The Functional Assessment Short Test (FAST) was used ... Read more >>

Eur Neuropsychopharmacol (European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology)
[2021, 49:54-68]

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Longitudinal allometry of sulcal morphology in health and schizophrenia

Joost Janssen, Clara Alloza, Covadonga Díaz-Caneja, Javier Santonja, Laura Pina-Camacho, Pedro Gordaliza, Alberto Fernández-Pena, Noemi González Lois, Elizabeth E.L. Buimer, Neeltje E.M. van Haren, Wiepke Cahn, Eduardo Vieta, Josefina Castro-Fornieles, Miquel Bernardo, Mara Parellada, Celso Arango, René Kahn, Hilleke Hulshoff Pol, Hugo Schnack,

Scaling between subcomponents of cortical folding and total brain volume (TBV) in healthy individuals (HI) is allometric, i.e. non-linear. It is unclear whether this is also true in individuals with schizophrenia (SZ) or first-episode psychosis (FEP). The current study first confirmed normative allometric scaling norms in HI using discovery and ... Read more >>

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The role of depression in the prediction of a "late" remission in first-episode psychosis: An analysis of the OPTiMiSE study.

David Fraguas, Covadonga M Díaz-Caneja, Laura Pina-Camacho, Inge Winter van Rossum, Lone Baandrup, Iris E Sommer, Birte Glenthøj, René S Kahn, Stefan Leucht, Celso Arango,

<h4>Objective</h4>The identification of predictors of psychosis remission could guide early clinical decision-making for treatment of first-episode schizophrenia (FES).<h4>Methods</h4>We analyzed two non-independent subsamples of patients with FES ages 18-40 years from the OPTiMiSE study dataset to investigate the demographic and clinical factors that might help to differentiate "late" remitters (i.e., not ... Read more >>

Schizophr Res (Schizophrenia research)
[2021, 231:100-107]

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Early signs of autism in infants whose mothers suffered from a threatened preterm labour: a 30-month prospective follow-up study.

Farah Ghosn, Pablo Navalón, Laura Pina-Camacho, Belén Almansa, Rosa Sahuquillo-Leal, Alba Moreno-Giménez, Vicente Diago, Máximo Vento, Ana García-Blanco,

Infants born after a threatened preterm labour (TPL infants) are at high risk of autism spectrum disorder (ASD). Studying this population may provide insight on the pathophysiological underpinnings of this condition. This study aimed to (i) ascertain the presence and autistic symptom load in TPL infants aged age 30 months relative ... Read more >>

Eur Child Adolesc Psychiatry (European child & adolescent psychiatry)
[2021, :]

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The functioning assessment short test (FAST) applied to first-episode psychosis: Psychometric properties and severity thresholds.

Silvia Amoretti, Gisela Mezquida, Adriane R Rosa, Miquel Bioque, Manuel J Cuesta, Laura Pina-Camacho, Clemente Garcia-Rizo, Fe Barcones, Ana González-Pinto, Jessica Merchán-Naranjo, Iluminada Corripio, Eduard Vieta, Inmaculada Baeza, Romina Cortizo, C Mar Bonnín, Carla Torrent, Miguel Bernardo, ,

Functional impairment is a defining feature of psychotic disorders. The Functional Assessment Short Test (FAST) is one of the most widely used instruments to measure psychosocial functioning. However, cut-offs of impairment have been well-established for bipolar disorders, but not for other clinical populations. This study aims to analyse psychometric properties of ... Read more >>

Eur Neuropsychopharmacol (European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology)
[2021, 47:98-111]

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Study of the pathophysiological mechanisms associated with the onset and course of neurodevelopmental disorders in preterm infants (the PeriSTRESS-PremTEA study): Rationale, objectives, design and sample description.

Pablo Navalón, Jéssica Merchan-Naranjo, Farah Ghosn, Belén Almansa, Consuelo Chafer-Pericas, Javier González-Peñas, Elisa Rodríguez-Toscano, Susana Zeballos, María Arriaga, Pedro Castro Castro, Dorotea Blanco Bravo, Máximo Vento, Laura Pina-Camacho, Ana García-Blanco,

<h4>Background</h4>There are few studies exploring the pathophysiological pathways that may condition differentially the emergence/course of neurodevelopmental disorders (ND) in very preterm and extremely preterm newborns (VPTN/EPTN). Furthermore, there are no established biological markers predictive of ND in this population. The aim of this study is four-fold: in two cohorts of ... Read more >>

Rev Psiquiatr Salud Ment (Revista de psiquiatria y salud mental)
[2021, :]

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Identifying clinical clusters with distinct trajectories in first-episode psychosis through an unsupervised machine learning technique.

Silvia Amoretti, Norma Verdolini, Gisela Mezquida, Francisco Diego Rabelo-da-Ponte, Manuel J Cuesta, Laura Pina-Camacho, Marta Gomez-Ramiro, Concepción De-la-Cámara, Ana González-Pinto, Covadonga M Díaz-Caneja, Iluminada Corripio, Eduard Vieta, Elena de la Serna, Anna Mané, Brisa Solé, André F Carvalho, Maria Serra, Miguel Bernardo,

The extreme variability in symptom presentation reveals that individuals diagnosed with a first-episode psychosis (FEP) may encompass different sub-populations with potentially different illness courses and, hence, different treatment needs. Previous studies have shown that sociodemographic and family environment factors are associated with more unfavorable symptom trajectories. The aim of this ... Read more >>

Eur Neuropsychopharmacol (European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology)
[2021, 47:112-129]

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Exploring Risk and Resilient Profiles for Functional Impairment and Baseline Predictors in a 2-Year Follow-Up First-Episode Psychosis Cohort Using Latent Class Growth Analysis.

Estela Salagre, Iria Grande, Brisa Solé, Gisela Mezquida, Manuel J Cuesta, Covadonga M Díaz-Caneja, Silvia Amoretti, Antonio Lobo, Ana González-Pinto, Carmen Moreno, Laura Pina-Camacho, Iluminada Corripio, Immaculada Baeza, Daniel Bergé, Norma Verdolini, André F Carvalho, Eduard Vieta, Miquel Bernardo, PEPs Group,

Being able to predict functional outcomes after First-Episode Psychosis (FEP) is a major goal in psychiatry. Thus, we aimed to identify trajectories of psychosocial functioning in a FEP cohort followed-up for 2 years in order to find premorbid/baseline predictors for each trajectory. Additionally, we explored diagnosis distribution within the different ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 10(1):]

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[Patient care, right to information and consent for minors in situations of parental conflict. Clinical guidelines in the context of Spanish legislation].

Laura Pina-Camacho, Jorge Vidal, María Dolores Picouto, Encarna Justo Ortiz, Federico de Montalvo Jääskeläinen, Carmen Moreno, Celso Arango, Teresa Hernández-Sampelayo, Mara Parellada, ,

Among the main social and legislative changes as regards family matters that have taken place in Spain in the last few years, are included: (i) the gradual increase in legal disputes between parents, and (ii) the introduction of Law 26/2015 on Child Protection, which modified Law 41/2002 on the Freedom ... Read more >>

An Pediatr (Engl Ed) (Anales de pediatria)
[2021, 94(5):338.e1-338.e7]

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Elevated Extracellular Free-Water in a Multicentric First-Episode Psychosis Sample, Decrease During the First 2 Years of Illness.

Daniel Bergé, Anna Mané, Tyler A Lesh, Miquel Bioque, Fe Barcones, Ana Maria Gonzalez-Pinto, Mara Parellada, Eduard Vieta, Josefina Castro-Fornieles, Roberto Rodriguez-Jimenez, Maria Paz García-Portilla, Judith Usall, Cameron S Carter, Bibiana Cabrera, Miguel Bernardo, Joost Janssen, ,

Recent diffusion imaging studies using free-water (FW) elimination have shown increased FW in gray matter (GM) and white matter (WM) in first-episode psychosis (FEP) and lower corrected fractional anisotropy (FAt) in WM in chronic schizophrenia. However, little is known about the longitudinal stability and clinical significance of these findings. To ... Read more >>

Schizophr Bull (Schizophrenia bulletin)
[2020, 46(4):846-856]

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The Positive and Negative Syndrome Scale for Schizophrenia Autism Severity Scale (PAUSS) in young people with autism and schizophrenia.

Laura Pina-Camacho, Leticia Boada, Covadonga M Díaz-Caneja, Alicia García-Alcón, Mónica Burdeus, Elena Serrano-Drozdowskyj, David Fraguas, Carmen Moreno, Mara Parellada,

<h4>Introduction</h4>Schizophrenia spectrum disorders (SSD) share symptoms with autism spectrum disorders (ASD). Autistic phenotypic profiles in SSD may be associated with a poor prognosis. We aimed to assess the evidences for reliability and convergent validity of the Positive and Negative Syndrome Scale for Schizophrenia (PANSS) Autism Severity Scale (PAUSS) in a ... Read more >>

Rev Psiquiatr Salud Ment (Revista de psiquiatria y salud mental)
[2020, 13(3):118-130]

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T25. THE RELATIONSHIP BETWEEN AGE AT FIRST-EPISODE AND LONGITUDINAL CORTICAL CHANGES IN FIRST-EPISODE PSYCHOSIS: A TWO-YEAR LONGITUDINAL STUDY IN AN ADOLESCENT AND ADULT-ONSET COHORT

Javier Santonja, Laura Pina-Camacho, Kenia Martínez, Covadonga Díaz-Caneja, Celso Arango, Miguel Bernardo Arroyo, Gisela Mezquida, Joost Janssen, Mara Parellada,

Abstract <h4>Background</h4> In a unique deeply phenotyped longitudinal dataset consisting of first-episode psychosis (FEP) patients with a wide age at FEP onset (15 to 35 years) and healthy controls, we aimed to determine whether cortical abnormalities are already present at FEP, whether they progress further over the first two years ... Read more >>

Schizophr Bull (Schizophrenia bulletin)
[2020, 46(Suppl 1):S240-S241]

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T117. PROMINENT AND PERSISTENT AUTISTIC TRAITS ARE ASSOCIATED WITH EARLY NON-REMISSION IN FIRST-EPISODE SCHIZOPHRENIA

Laura Pina-Camacho, Covadonga M Diaz-Caneja, David Fraguas, Leticia Boada, Mara Parellada, Inge Winter-van Rossum, Rene Kahn, Celso Arango,

Abstract <h4>Background</h4> Autistic phenotypic profiles in patients with schizophrenia are reportedly associated with poor outcomes, including higher odds of antipsychotic treatment failure. The Positive and Negative Syndrome Scale for Schizophrenia (PANSS) Autism Severity Scale (PAUSS) has been validated as a tool to identify “autistic profiles” in adolescents and adults with ... Read more >>

Schizophr Bull (Schizophrenia bulletin)
[2020, 46(Suppl 1):S275-S275]

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S18. STRUCTURAL COVARIANCE PREDICTORS OF CLINICAL IMPROVEMENT AT 2-YEAR FOLLOW-UP IN FIRST-EPISODE PSYCHOSIS

Cristina Saiz-Masvidal, Carles Soriano-Mas, Fernando Contreras, Gisela Mezquida, Antonio Lobo, Ana González-Pinto, Laura Pina-Camacho, Mara Parellada, Bernardo Miguel,

Abstract <h4>Background</h4> Neural correlates of psychotic disorders encompass multiple brain regions in multiple brain circuits, even at early stages. Previous research has characterized structural brain alterations in first-episode psychosis (FEP), but few studies have focused on the relationship between brain alterations and disease trajectories. First psychotic episodes typically evolve into ... Read more >>

Schizophr Bull (Schizophrenia bulletin)
[2020, 46(Suppl 1):S37-S37]

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The longitudinal effect of antipsychotic burden on psychosocial functioning in first-episode psychosis patients: the role of verbal memory.

Alejandro Ballesteros, Ana M Sánchez Torres, Jose López-Ilundáin, Gisela Mezquida, Antonio Lobo, Ana González-Pinto, Laura Pina-Camacho, Iluminada Corripio, Eduard Vieta, Elena de la Serna, Anna Mané, Miquel Bioque, Lucía Moreno-Izco, Ana Espliego, Ruth Lorente-Omeñaca, Silvia Amoretti, Miguel Bernardo, Manuel J Cuesta, ,

<h4>Background</h4>Previous literature supports antipsychotics' (AP) efficacy in acute first-episode psychosis (FEP) in terms of symptomatology and functioning but also a cognitive detrimental effect. However, regarding functional recovery in stabilised patients, these effects are not clear. Therefore, the main aim of this study is to investigate dopaminergic/anticholinergic burden of (AP) on ... Read more >>

Psychol Med (Psychological medicine)
[2020, :1-10]

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Birth weight and antipsychotic induced weight gain: A prenatal programming approach in the PEPs study.

Clemente García-Rizo, Miquel Bioque, Gisela Mezquida, Silvia Amoretti, Manuel J Cuesta, Covadonga M Díaz-Caneja, Sergi Mas, Antonio Lobo, Ana González-Pinto, David Fraguas, Iluminada Corripio, Eduard Vieta, Inmaculada Baeza, Daniel Bergé, Emilio Fernandez-Egea, Marina Garriga, Miguel Bernardo, ,

Schizophr Res (Schizophrenia research)
[2020, 218:292-294]

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Dietary Interventions for Autism Spectrum Disorder: A Meta-analysis.

David Fraguas, Covadonga M Díaz-Caneja, Laura Pina-Camacho, Carmen Moreno, Manuel Durán-Cutilla, Miriam Ayora, Emiliano González-Vioque, Mario de Matteis, Robert L Hendren, Celso Arango, Mara Parellada,

<h4>Context</h4>Dietary interventions such as restrictive diets or supplements are common treatments for young people with autism spectrum disorder (ASD). Evidence for the efficacy of these interventions is still controversial.<h4>Objective</h4>To assess the efficacy of specific dietary interventions on symptoms, functions, and clinical domains in subjects with ASD by using a meta-analytic ... Read more >>

Pediatrics (Pediatrics)
[2019, 144(5):]

Cited: 5 times

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Sensory-to-Cognitive Systems Integration Is Associated With Clinical Severity in Autism Spectrum Disorder.

Kenia Martínez, Magdalena Martínez-García, Luis Marcos-Vidal, Joost Janssen, Francisco X Castellanos, Clara Pretus, Óscar Villarroya, Laura Pina-Camacho, Covadonga M Díaz-Caneja, Mara Parellada, Celso Arango, Manuel Desco, Jorge Sepulcre, Susanna Carmona,

<h4>Objective</h4>Impaired multisensory integration in autism spectrum disorder (ASD) may arise from functional dysconnectivity among brain systems. Our study examines the functional connectivity integration between primary modal sensory regions and heteromodal processing cortex in ASD, and whether abnormalities in network integration relate to clinical severity.<h4>Method</h4>We studied a sample of 55 high-functioning ... Read more >>

J Am Acad Child Adolesc Psychiatry (Journal of the American Academy of Child and Adolescent Psychiatry)
[2020, 59(3):422-433]

Cited: 2 times

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Neutrophil Count Is Associated With Reduced Gray Matter and Enlarged Ventricles in First-Episode Psychosis.

Christian Núñez, Christian Stephan-Otto, Judith Usall, Miquel Bioque, Antonio Lobo, Ana González-Pinto, Laura Pina-Camacho, Eduard Vieta, Josefina Castro-Fornieles, Roberto Rodriguez-Jimenez, Anna Butjosa, Joost Janssen, Bibiana Cabrera, Mara Parellada, Miquel Bernardo, ,

Although there is recent evidence that cells from the peripheral immune system can gain access to the central nervous system in certain conditions such as multiple sclerosis, their role has not been assessed in psychosis. Here, we aimed to explore whether blood cell count was associated with brain volume and/or ... Read more >>

Schizophr Bull (Schizophrenia bulletin)
[2019, 45(4):846-858]

Cited: 7 times

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Auditory hallucinations in first-episode psychosis: A voxel-based morphometry study.

María Jose Escarti, Gracian Garcia-Marti, Roberto Sanz-Requena, Luis Marti-Bonmatí, Bibiana Cabrera, Eduard Vieta, Antonio Lobo, Josefina Castro-Fornieles, Ana González-Pinto, Romina Cortizo, Laura Pina-Camacho, Mara Parellada, Miquel Bernardo, Julio Sanjuan, ,

BACKGROUND:Auditory hallucinations (AH) are a core symptom of psychosis. The brain abnormalities responsible for AH remain controversial due to inconsistent and conflicting findings across studies, with substantial confounding factors, such as chronicity. Few studies have examined the pathological changes that occur in the gray matter (GM) of patients with first-episode ... Read more >>

Schizophr Res (Schizophrenia research)
[2019, 209:148-155]

Cited: 1 time

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Cannabinoid hyperemesis in adolescents: A poorly diagnosed syndrome.

Gonzalo Solis-Garcia, Felipe González-Martínez, Elena Urbiola, Juan J Carballo, Jimena Perez-Moreno, Rosa Rodríguez-Fernández, Dolores Moreno, Laura Pina-Camacho,

J Paediatr Child Health (Journal of paediatrics and child health)
[2019, 55(10):1264-1266]

Cited: 1 time

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Predictors of Placebo Response in Pharmacological Clinical Trials of Negative Symptoms in Schizophrenia: A Meta-regression Analysis.

David Fraguas, Covadonga M Díaz-Caneja, Laura Pina-Camacho, Daniel Umbricht, Celso Arango,

We conducted a meta-regression analysis of all double-blind, randomized, placebo-controlled clinical trials (DBRCTs) reporting effects of drug and placebo on negative symptoms in people with stable schizophrenia and predominant or prominent negative symptoms to assess predictors of placebo response in these individuals. We used Preferred Reporting Items for Systematic Reviews ... Read more >>

Schizophr Bull (Schizophrenia bulletin)
[2019, 45(1):57-68]

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Negative Symptoms in Early-Onset Psychosis and Their Association With Antipsychotic Treatment Failure.

Johnny Downs, Harry Dean, Suzannah Lechler, Nicola Sears, Rashmi Patel, Hitesh Shetty, Matthew Hotopf, Tamsin Ford, Marinos Kyriakopoulos, Covadonga M Diaz-Caneja, Celso Arango, James H MacCabe, Richard D Hayes, Laura Pina-Camacho,

The prevalence of negative symptoms (NS) at first episode of early-onset psychosis (EOP), and their effect on psychosis prognosis is unclear. In a sample of 638 children with EOP (aged 10-17 y, 51% male), we assessed (1) the prevalence of NS at first presentation to mental health services and (2) ... Read more >>

Schizophr Bull (Schizophrenia bulletin)
[2019, 45(1):69-79]

Cited: 10 times

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Neuroanatomical deficits shared by youth with autism spectrum disorders and psychotic disorders.

Covadonga M Díaz-Caneja, Hugo Schnack, Kenia Martínez, Javier Santonja, Yasser Alemán-Gomez, Laura Pina-Camacho, Carmen Moreno, David Fraguas, Celso Arango, Mara Parellada, Joost Janssen,

Autism spectrum disorders (ASD) and early-onset psychosis (EOP) are neurodevelopmental disorders that share genetic, clinical and cognitive facets; it is unclear if these disorders also share spatially overlapping cortical thickness (CT) and surface area (SA) abnormalities. MRI scans of 30 ASD, 29 patients with early-onset first-episode psychosis (EO-FEP) and 26 ... Read more >>

Hum Brain Mapp (Human brain mapping)
[2019, 40(5):1643-1653]

Cited: 2 times

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