Full Text Journal Articles by
Author Laura M Yates


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Maternal characteristics and pregnancy outcomes of hospitalized pregnant women with SARS-CoV-2 infection in South Africa: An International Network of Obstetric Survey Systems-based cohort study.

Samantha Budhram, Valerie Vannevel, Tanita Botha, Lawrence Chauke, Shastra Bhoora, Gaynor M Balie, Natalie Odell, Hennie Lombaard, Amy Wise, Chrysanthi Georgiou, Nondumiso Ngxola, Emma Wynne, Unati Mbewu, Mfundo Mabenge, Sibusiso Phinzi, Nontsikelelo Gubu-Ntaba, Gareth Goldman, Kay Tunkyi, Sudhir Prithipal, Keshree Naidoo, Santhi Venkatachalam, Terence Moodley, Sean Mould, Mzuvele Hlabisa, Logie Govender, Charlene Maistry, John P Habineza, Priya Israel, Serantha Foolchand, Nomandla V Tsibiyane, Mala Panday, Priya Soma-Pillay, Sumaiya Adam, Felicia Molokoane, Matthew S Mojela, Elizabeth J van Rensburg, Tshililo Mashamba, Mushi Matjila, Sue Fawcus, Ayesha Osman, Mareli Venter, Gregory Petro, Ahminah Fakier, Eduard Langenegger, Catherine A Cluver, Adrie Bekker, Liesl de Waard, Chantal Stewart, Nnabuike C Ngene, Ongombe Lunda, Sylvia N Cebekhulu, Siva Moodley, Mama-Asu Koranteng-Peprah, Emmanuel M C Ati, Salome Maswime, Laura M Yates,

<h4>Objective</h4>To describe risk factors and outcomes of pregnant women infected with SARS-CoV-2 admitted to South African healthcare facilities.<h4>Methods</h4>A population-based cohort study was conducted utilizing an amended International Obstetric Surveillance System protocol. Data on pregnant women with SARS-CoV-2 infection, hospitalized between April 14, 2020, and November 24, 2020, were analyzed.<h4>Results</h4>A total ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, :]

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Nine newly identified individuals refine the phenotype associated with MYT1L mutations.

Isabelle C Windheuser, Jessica Becker, Kirsten Cremer, Hela Hundertmark, Laura M Yates, Elisabeth Mangold, Sophia Peters, Franziska Degenhardt, Kerstin U Ludwig, Alexander M Zink, Davor Lessel, Tatjana Bierhals, Theresia Herget, Jessika Johannsen, Jonas Denecke, Eva Wohlleber, Tim M Strom, Dagmar Wieczorek, Marta Bertoli, Roberto Colombo, Maja Hempel, Hartmut Engels,

Both point mutations and deletions of the MYT1L gene as well as microdeletions of chromosome band 2p25.3 including MYT1L are associated with intellectual disability, obesity, and behavioral problems. Thus, MYT1L is assumed to be the-at least mainly-causative gene in the 2p25.3 deletion syndrome. Here, we present comprehensive descriptions of nine ... Read more >>

Am J Med Genet A (American journal of medical genetics. Part A)
[2020, 182(5):1021-1031]

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British Association for Psychopharmacology consensus guidance on the use of psychotropic medication preconception, in pregnancy and postpartum 2017.

R Hamish McAllister-Williams, David S Baldwin, Roch Cantwell, Abby Easter, Eilish Gilvarry, Vivette Glover, Lucian Green, Alain Gregoire, Louise M Howard, Ian Jones, Hind Khalifeh, Anne Lingford-Hughes, Elizabeth McDonald, Nadia Micali, Carmine M Pariante, Lesley Peters, Ann Roberts, Natalie C Smith, David Taylor, Angelika Wieck, Laura M Yates, Allan H Young, ,

Decisions about the use of psychotropic medication in pregnancy are an ongoing challenge for clinicians and women with mental health problems, owing to the uncertainties around risks of the illness itself to mother and fetus/infant, effectiveness of medications in pregnancy and risks to the fetus/infant from in utero exposure or ... Read more >>

J Psychopharmacol (Journal of psychopharmacology (Oxford, England))
[2017, 31(5):519-552]

Cited: 30 times

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Pregnancy outcome following maternal exposure to pregabalin may call for concern.

Ursula Winterfeld, Paul Merlob, David Baud, Valentin Rousson, Alice Panchaud, Laura E Rothuizen, Nathalie Bernard, Thierry Vial, Laura M Yates, Alessandra Pistelli, Maria Ellfolk, Georgios Eleftheriou, Loes C de Vries, Annie-Pierre Jonville-Bera, Mine Kadioglu, Jerome Biollaz, Thierry Buclin,

<h4>Objective</h4>To investigate pregnancy outcomes following maternal use of pregabalin.<h4>Methods</h4>This multicenter, observational prospective cohort study compared pregnancy outcomes in women exposed to pregabalin with those of matched controls (not exposed to any medications known to be teratogenic or to any antiepileptic drugs). Teratology Information Services systematically collected data between 2004 and ... Read more >>

Neurology (Neurology)
[2016, 86(24):2251-2257]

Cited: 20 times

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Microdeletion 1p35.2: a recognizable facial phenotype with developmental delay.

Brian T Wilson, Murwan Omer, Stephen W Hellens, Simon A Zwolinski, Laura M Yates, Sally Ann Lynch,

We describe two patients with microdeletion 1p35.2, intrauterine growth retardation, small stature, hypermetropia, hearing impairment and developmental delay. Both patients have long, myopathic facies, with fine eyebrows, small mouths and micrognathia. We postulate a role for the histone deacetylase HDAC1 in the facial phenotype and suggest that deletion of KPNA6 ... Read more >>

Am J Med Genet A (American journal of medical genetics. Part A)
[2015, 167A(8):1916-1920]

Cited: 2 times

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Prescribing without evidence - pregnancy.

Simon H L Thomas, Laura M Yates,

Prescribing of medicines during pregnancy is common, and for some groups of women is essential for maintaining maternal and therefore fetal health. Pregnant women and prescribers are rightly concerned, however, about the potential adverse fetal effects of medicines. These may include fetal death or stillbirth, congenital malformations, developmental impairment, neonatal ... Read more >>

Br J Clin Pharmacol (British journal of clinical pharmacology)
[2012, 74(4):691-697]

Cited: 18 times

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Pregnancy outcomes following gabapentin use: results of a prospective comparative cohort study.

Hisaki Fujii, Akash Goel, Nathalie Bernard, Alessandra Pistelli, Laura M Yates, Sally Stephens, Jungyeol Y Han, Doreen Matsui, Fatwa Etwell, Thomas R Einarson, Gideon Koren, Adrienne Einarson,

<h4>Objectives</h4>Our objectives were to 1) determine whether first-trimester use of gabapentin is associated with an increased risk for major malformations; 2) examine rates of spontaneous abortions, therapeutic abortions, stillbirths, mean birth weight and gestational age at delivery; and 3) examine rates of poor neonatal adaptation syndrome following late pregnancy exposure.<h4>Methods</h4>The ... Read more >>

Neurology (Neurology)
[2013, 80(17):1565-1570]

Cited: 31 times

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Cilia and disease.

Lorraine Eley, Laura M Yates, Judith A Goodship,

Cilia are classified according to their microtubule components as 9+2 (motile) and 9+0 (primary) cilia. Disruption of 9+2 cilia, which move mucus across respiratory epithelia, leads to rhinitis, sinusitis and bronchiectasis. Approximately half of the patients with primary ciliary dyskinesia (PCD) have situs inversus, providing a link between left-right asymmetry ... Read more >>

Curr Opin Genet Dev (Current opinion in genetics & development)
[2005, 15(3):308-314]

Cited: 88 times

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A perspective on inversin.

Lorraine Eley, Lee Turnpenny, Laura M Yates, A Scott Craighead, David Morgan, Catherine Whistler, Judith A Goodship, Tom Strachan,

Over the past 5 years, there has been increasing evidence for the role of primary (9+0) cilia in renal physiology and in establishing the left-right axis. The cilia in the renal tract are immotile and thought to have a sensory function. Cilia at the murine embryonic node have a vortical ... Read more >>

Cell Biol Int (Cell biology international)
[2004, 28(2):119-124]

Cited: 24 times

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Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle.

David Morgan, Lorraine Eley, John Sayer, Tom Strachan, Laura M Yates, A Scott Craighead, Judith A Goodship,

Homozygous inv mice lack a functional inversin protein and exhibit situs inversus plus severe cystic changes in the kidney and pancreas. Although the inversin sequence has provided few clues to its function, we and others have previously identified calmodulin as a binding partner. We now provide evidence that inversin interacts ... Read more >>

Hum Mol Genet (Human molecular genetics)
[2002, 11(26):3345-3350]

Cited: 92 times

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