Full Text Journal Articles by
Author Lance D Burrell

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Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.

Conan G Kinsey, Soledad A Camolotto, Amelie M Boespflug, Katrin P Guillen, Mona Foth, Amanda Truong, Sophia S Schuman, Jill E Shea, Michael T Seipp, Jeffrey T Yap, Lance D Burrell, David H Lum, Jonathan R Whisenant, G Weldon Gilcrease, Courtney C Cavalieri, Kaitrin M Rehbein, Stephanie L Cutler, Kajsa E Affolter, Alana L Welm, Bryan E Welm, Courtney L Scaife, Eric L Snyder, Martin McMahon,

Pancreatic ductal adenocarcinoma (PDA) was responsible for ~ 44,000 deaths in the United States in 2018 and is the epitome of a recalcitrant cancer driven by a pharmacologically intractable oncoprotein, KRAS1-4. Downstream of KRAS, the RAF→MEK→ERK signaling pathway plays a central role in pancreatic carcinogenesis5. However, paradoxically, inhibition of this pathway ... Read more >>

Nat Med (Nature medicine)
[2019, 25(4):620-627]

Cited: 51 times

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Publisher Correction: Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.

Conan G Kinsey, Soledad A Camolotto, Amelie M Boespflug, Katrin P Guillen, Mona Foth, Amanda Truong, Sophia S Schuman, Jill E Shea, Michael T Seipp, Jeffrey T Yap, Lance D Burrell, David H Lum, Jonathan R Whisenant, G Weldon Gilcrease, Courtney C Cavalieri, Kaitrin M Rehbein, Stephanie L Cutler, Kajsa E Affolter, Alana L Welm, Bryan E Welm, Courtney L Scaife, Eric L Snyder, Martin McMahon,

In the version of this article initially published, the label over the bottom schematic in Fig. 1a was "pH > 5.0"; it should have been "pH < 5.0". Further, the original article misspelt the surname of Katrin P. Guillen as "Gullien". These errors have been corrected in the print, PDF ... Read more >>

Nat Med (Nature medicine)
[2019, 25(5):861]

Cited: 2 times

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Mentoring and the Nuclear Medicine Technologist.

Lance D Burrell,

Mentoring has a rich tradition throughout history. Capable instructors and experienced nuclear medicine technologists guide the path of the new trainee, with success being determined by the quality of the mentorship that takes place. This article provides an overview of mentoring for nuclear medicine technologists, including what it is, how ... Read more >>

J Nucl Med Technol (Journal of nuclear medicine technology)
[2018, 46(3):231-236]

Cited: 0 times

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Correlation of Glioma Proliferation and Hypoxia by Luciferase, Magnetic Resonance, and Positron Emission Tomography Imaging.

Michael Karsy, David L Gillespie, Kevin P Horn, Lance D Burrell, Jeffery T Yap, Randy L Jensen,

Gliomas are the most common type of primary, malignant brain tumor and significantly impact patients, who have a median survival of ~1 year depending on mutational background. Novel imaging modalities such as luciferase bioluminescence, micro-magnetic resonance imaging (micro-MRI), micro-computerized tomography (micro-CT), and micro-positron emission tomography (micro-PET) have expanded the portfolio of ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2018, 1742:301-320]

Cited: 0 times

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18F-FDG and Amyloid PET in Dementia.

Lance D Burrell, Dawn Holley,

We present a case of memory loss and aphasia in a 72-y-old man and discuss how PET imaging supported a diagnosis of Alzheimer dementia despite conflicting clinical findings. ... Read more >>

J Nucl Med Technol (Journal of nuclear medicine technology)
[2018, 46(2):151-152]

Cited: 0 times

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The Influential Role of BCL2 Family Members in Synovial Sarcomagenesis.

Jared J Barrott, Ju-Fen Zhu, Kyllie Smith-Fry, Asia M Susko, Dakota Nollner, Lance D Burrell, Amir Pozner, Mario R Capecchi, Jeffrey T Yap, Lisa A Cannon-Albright, Xingming Deng, Kevin B Jones,

Synovial sarcomas are deadly soft tissue malignancies associated with t(X;18) balanced chromosomal translocations. Expression of the apoptotic regulator BCL2 is prominent in synovial sarcomas and has prompted the hypothesis that synovial sarcomagenesis may depend on it. Herein, it is demonstrated that Bcl2 overexpression enhances synovial sarcomagenesis in an animal model. ... Read more >>

Mol Cancer Res (Molecular cancer research : MCR)
[2017, 15(12):1733-1740]

Cited: 1 time

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Relationship between 18F-Flutemetamol uptake and RBANS performance in non-demented community-dwelling older adults.

Dustin B Hammers, Taylor J Atkinson, Bonnie C A Dalley, Kayla R Suhrie, Britney E Beardmore, Lance D Burrell, Kevin P Horn, Kelli M Rasmussen, Norman L Foster, Kevin Duff, John M Hoffman,

OBJECTIVE:The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) has been used extensively for clinical care and in research for patients with mild cognitive impairment and Alzheimer's disease (AD); however, relatively few studies have evaluated the relationship between RBANS performance and AD imaging biomarkers. The purpose of the current ... Read more >>

Clin Neuropsychol (The Clinical neuropsychologist)
[2017, 31(3):531-543]

Cited: 1 time

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Amyloid Positivity Using [18F]Flutemetamol-PET and Cognitive Deficits in Nondemented Community-Dwelling Older Adults.

Dustin B Hammers, Taylor J Atkinson, Bonnie C A Dalley, Kayla R Suhrie, Kevin P Horn, Kelli M Rasmussen, Britney E Beardmore, Lance D Burrell, Kevin Duff, John M Hoffman,

Little research exists examining the relationship between beta-amyloid neuritic plaque density via [18F]flutemetamol binding and cognition; consequently, the purpose of the current study was to compare cognitive performances among individuals having either increased amyloid deposition (Flute+) or minimal amyloid deposition (Flute-). Twenty-seven nondemented community-dwelling adults over the age of 65 ... Read more >>

Am J Alzheimers Dis Other Demen (American journal of Alzheimer's disease and other dementias)
[2017, 32(6):320-328]

Cited: 1 time

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Biopsy of a complicated right atrial mass using CARTO 3-dimensional electro-anatomic mapping.

Lance D Burrell, Peter J Weiss, Brian K Whisenant,

We report the successful biopsy of a right atrial fatty mass using CARTO 3-dimensional electro-anatomic mapping fused with cardiac MRI. Fluoroscopic guidance within the cardiac chambers lacks precision and therefore risks geographical miss of the intended target and cardiac perforation. CARTO mapping fused with cardiac MRI facilitated precise navigation of ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2014, 84(7):E61-4]

Cited: 0 times

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Usefulness of left atrial appendage volume as a predictor of embolic stroke in patients with atrial fibrillation.

Lance D Burrell, Benjamin D Horne, Jeffrey L Anderson, J Brent Muhlestein, Brian K Whisenant,

Stroke prevention in atrial fibrillation (AF) is guided by clinical factors with inadequate predictive power. Most thrombi observed in AF are observed in the left atrial appendage (LAA). This study was designed to determine (1) the association between LAA and the incidence of AF-related stroke and (2) the power of ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2013, 112(8):1148-1152]

Cited: 16 times

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