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Genome-wide association analyses of common infections in a large practice-based biobank.

Lan Jiang, V Eric Kerchberger, Christian Shaffer, Alyson L Dickson, Michelle J Ormseth, Laura L Daniel, Barbara G Carranza Leon, Nancy J Cox, Cecilia P Chung, Wei-Qi Wei, C Michael Stein, QiPing Feng,

<h4>Introduction</h4>Infectious diseases are common causes of morbidity and mortality worldwide. Susceptibility to infection is highly heritable; however, little has been done to identify the genetic determinants underlying common infectious diseases. One GWAS was performed using 23andMe information about self-reported infections; we set out to confirm previous loci and identify new ... Read more >>

BMC Genomics (BMC genomics)
[2022, 23(1):672]

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Developing a Versatile Multiscale Therapeutic Platform for Osteosarcoma Synergistic Photothermo-Chemotherapy with Effective Osteogenicity and Antibacterial Capability.

Yunlong Ma, Lan Jiang, Jie Hu, Enjun Zhu, Nan Zhang,

Osteosarcoma is a devastating malignant neoplasm that seriously threatens human health. After an osteosarcoma resection, the simultaneous treatment of tumor recurrence, postoperative infection, and large bone loss remains a formidable challenge clinically. Herein, a versatile multiscale therapeutic platform ([email protected]) is engineered based on NiTi alloys with versatile properties for near-infrared ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2022, :]

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