Full Text Journal Articles by
Author Kristin F Phillips

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Neuroscience: The New English Major?

Kristin F Phillips, Harald Sontheimer,

Once strictly the domain of medical and graduate education, neuroscience has made its way into the undergraduate curriculum with over 230 colleges and universities now offering a bachelor's degree in neuroscience. The disciplinary focus on the brain teaches students to apply science to the understanding of human behavior, human interactions, ... Read more >>

Neuroscientist (The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry)
[2021, :10738584211003992]

Cited: 0 times

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Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness.

Kristin F Phillips, Edna Santos, Robert E Blair, Laxmikant S Deshpande,

Gulf War Illness (GWI) is a chronic multi-symptom disorder afflicting the veterans of the First Gulf War, and includes neurological symptoms characterized by depression and memory deficits. Chronic exposure to organophosphates (OPs) is considered a leading cause for GWI, yet its pathobiology is not fully understood. We recently observed chronic ... Read more >>

Toxicol Sci (Toxicological sciences : an official journal of the Society of Toxicology)
[2019, 169(2):567-578]

Cited: 4 times

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Chronic Neurological Morbidities and Elevated Hippocampal Calcium Levels in a DFP-Based Rat Model of Gulf War Illness.

Kristin F Phillips, Laxmikant S Deshpande,

Over 20 yr have elapsed since the end of the First Gulf War, yet approximately one-third of the veterans exhibit Gulf War Illness (GWI) symptoms, particularly depression and memory impairments. Exposure to organophosphate (OP) compounds is implicated for GWI development. The role of calcium (Ca2+) signaling in learning, memory, and ... Read more >>

Mil Med (Military medicine)
[2018, 183(suppl_1):552-555]

Cited: 6 times

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Role of the calcium plateau in neuronal injury and behavioral morbidities following organophosphate intoxication.

Laxmikant S Deshpande, Robert E Blair, Kristin F Phillips, Robert J DeLorenzo,

Organophosphate (OP) chemicals include nerve agents and pesticides, and there is a growing concern of OP-based chemical attacks against civilians. Current antidotes are essential in limiting immediate mortality associated with OP exposure. However, further research is needed to identify the molecular mechanisms underlying long-term neurological deficits following survival of OP ... Read more >>

Ann N Y Acad Sci (Annals of the New York Academy of Sciences)
[2016, 1374(1):176-183]

Cited: 9 times

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Repeated low-dose organophosphate DFP exposure leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness.

Kristin F Phillips, Laxmikant S Deshpande,

Approximately 175,000-250,000 of the returning veterans from the 1991 Persian Gulf War exhibit chronic multi-symptom illnesses that includes neurologic co-morbidities such as depression, anxiety and cognitive impairments. Amongst a host of causative factors, exposure to low levels of the nerve agent Sarin has been strongly implicated for expression of Gulf ... Read more >>

Neurotoxicology (Neurotoxicology)
[2016, 52:127-133]

Cited: 25 times

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Hypothermia reduces calcium entry via the N-methyl-D-aspartate and ryanodine receptors in cultured hippocampal neurons.

Kristin F Phillips, Laxmikant S Deshpande, Robert J DeLorenzo,

Hypothermia is a powerful neuroprotective method when induced following cardiac arrest, stroke, and traumatic brain injury. The physiological effects of hypothermia are multifaceted and therefore a better knowledge of its therapeutic targets will be central to developing innovative combination therapies to augment the protective benefits of hypothermia. Altered neuronal calcium ... Read more >>

Eur J Pharmacol (European journal of pharmacology)
[2013, 698(1-3):186-192]

Cited: 7 times

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