Kristen S Uchtmann, Julia A Taylor, Barry G Timms, Richard W Stahlhut, Emily A Ricke, Mark R Ellersieck, Frederick S Vom Saal, William A Ricke,
Bisphenol A (BPA) is a contaminant in virtually all Americans. To examine BPA's adverse effects, the FDA-NCTR, NIEHS, and 14 groups of academic scientists formed a consortium: CLARITY-BPA. The purpose of our study was to investigate the effects of a wide range of doses of BPA on fetal development of ... Read more >>
Reprod Toxicol (Reproductive toxicology (Elmsford, N.Y.))
[2020, 91:131-141]
Cited: 2 times
Jill A Macoska, Kristen S Uchtmann, Glen E Leverson, Kevin T McVary, William A Ricke,
<h4>Purpose</h4>Medications targeting androgen receptor activity (eg finasteride) or smooth muscle contractility (eg doxazosin) do not resolve lower urinary tract symptoms indicative of lower urinary tract dysfunction in an important subgroup of men. Recently fibrosis has been implicated as another pathobiology contributing to male lower urinary tract symptoms but to our ... Read more >>
J Urol (The Journal of urology)
[2019, 202(6):1240-1247]
Cited: 1 time
Kristen Uchtmann, Electa R Park, Alexis Bergsma, Justin Segula, Mathew J Edick, Cindy K Miranti,
Integrin αIIbβ3 is critical for platelet-mediated blood clotting. Tetraspanins are well-established regulators of integrins and genetic loss of tetraspanin CD151 or TSSC6 in mice leads to increased bleeding due to inadequate integrin αIIbβ3 outside-in signaling. Conversely, mild but enhanced integrin αIIbβ3 activation and hyperaggregation is observed in CD9 and CD63 ... Read more >>
Exp Cell Res (Experimental cell research)
[2015, 339(2):261-269]
Cited: 9 times
Tristan M Nicholson, Kristen S Uchtmann, Conrad D Valdez, Ashleigh B Theberge, Tihomir Miralem, William A Ricke,
New therapies for two common prostate diseases, prostate cancer (PrCa) and benign prostatic hyperplasia (BPH), depend critically on experiments evaluating their hormonal regulation. Sex steroid hormones (notably androgens and estrogens) are important in PrCa and BPH; we probe their respective roles in inducing prostate growth and carcinogenesis in mice with ... Read more >>
J Vis Exp (Journal of visualized experiments : JoVE)
[2013, (78):]
Cited: 4 times