Full Text Journal Articles by
Author Kristen R Hamilton

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Striatal bases of temporal discounting in early adolescents.

Kristen R Hamilton, Jason F Smith, Stefanie F Gonçalves, Jazlyn A Nketia, Olivia N Tasheuras, Mark Yoon, Katya Rubia, Theresa J Chirles, Carl W Lejuez, Alexander J Shackman,

Steeper rates of temporal discounting-the degree to which smaller-sooner (SS) rewards are preferred over larger-later (LL) ones-have been associated with impulsive and ill-advised behaviors in adolescence. Yet, the underlying neural systems remain poorly understood. Here we used a well-established temporal discounting paradigm and functional MRI (fMRI) to examine engagement of ... Read more >>

Neuropsychologia (Neuropsychologia)
[2020, 144:107492]

Cited: 0 times

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Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment.

Annabelle M Belcher, Thomas O Cole, Aaron D Greenblatt, Stephen W Hoag, David H Epstein, Michael Wagner, Amy S Billing, Ebonie Massey, Kristen R Hamilton, Zofia K Kozak, Christopher J Welsh, Eric Weintraub, Emerson M Wickwire, Eric D Wish, Ted J Kaptchuk, Luana Colloca,

INTRODUCTION:More than 2 million individuals in the USA have an opioid use disorder (OUD). Methadone maintenance treatment is the gold standard of medication-based treatment for OUD, but high-dose methadone is associated with cardiotoxicity and respiratory complications, among other side effects. These adverse effects make enhancing the effectiveness of lower doses of ... Read more >>

BMJ Open (BMJ open)
[2019, 9(6):e026604]

Cited: 1 time

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Trait impulsivity during early adolescence predicts steepness of alcohol use escalation across adolescence.

Kristen R Hamilton, Julia W Felton, Stefanie F Gonçalves, Olivia N Tasheuras, Mark Yoon, Carl W Lejuez,

BACKGROUND AND AIMS:Alcohol use during adolescence is a significant public health concern with serious implications. Both early initiation and rate of escalation of alcohol use during adolescence forecast long-term alcohol-related difficulties and alcohol use disorders (AUDs), underscoring the need to understand psychological factors that contribute to these risk behaviors. One ... Read more >>

Addict Behav (Addictive behaviors)
[2019, 98:106017]

Cited: 0 times

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White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine.

Kristen P Morie, Sarah W Yip, Zu Wei Zhai, Jiansong Xu, Kristen R Hamilton, Rajita Sinha, Linda C Mayes, Marc N Potenza,

Prenatal cocaine exposure (PCE) is associated with risk-taking behaviors, including increased initiation of substance use in adolescence. The neurobiological underpinnings of these behaviors in adolescents with PCE are not well understood. The goal of this study was to compare diffusion-weighted imaging data between adolescents with and without PCE using crossing-fiber ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2017, 174:23-29]

Cited: 4 times

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Rapid-response impulsivity: definitions, measurement issues, and clinical implications.

Kristen R Hamilton, Andrew K Littlefield, Noelle C Anastasio, Kathryn A Cunningham, Latham H L Fink, Victoria C Wing, Charles W Mathias, Scott D Lane, Christian G Schütz, Alan C Swann, C W Lejuez, Luke Clark, F Gerard Moeller, Marc N Potenza,

Impulsivity is a multifaceted construct that is a core feature of multiple psychiatric conditions and personality disorders. However, progress in understanding and treating impulsivity is limited by a lack of precision and consistency in its definition and assessment. Rapid-response impulsivity (RRI) represents a tendency toward immediate action that occurs with ... Read more >>

Personal Disord (Personality disorders)
[2015, 6(2):168-181]

Cited: 30 times

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Choice impulsivity: Definitions, measurement issues, and clinical implications.

Kristen R Hamilton, Marci R Mitchell, Victoria C Wing, Iris M Balodis, Warren K Bickel, Mark Fillmore, Scott D Lane, C W Lejuez, Andrew K Littlefield, Maartje Luijten, Charles W Mathias, Suzanne H Mitchell, T Celeste Napier, Brady Reynolds, Christian G Schütz, Barry Setlow, Kenneth J Sher, Alan C Swann, Stephanie E Tedford, Melanie J White, Catharine A Winstanley, Richard Yi, Marc N Potenza, F Gerard Moeller,

Impulsivity critically relates to many psychiatric disorders. Given the multifaceted construct that impulsivity represents, defining core aspects of impulsivity is vital for the assessment and understanding of clinical conditions. Choice impulsivity (CI), involving the preferential selection of smaller sooner rewards over larger later rewards, represents one important type of impulsivity. ... Read more >>

Personal Disord (Personality disorders)
[2015, 6(2):182-198]

Cited: 57 times

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Brief report: The interaction of impulsivity with risk-taking is associated with early alcohol use initiation.

Kristen R Hamilton, Julia W Felton, Cristina M Risco, C W Lejuez, Laura MacPherson,

Early alcohol use initiation is a well-established risk factor for the subsequent development of alcohol abuse and dependence. Separate lines of research indicate that impulsivity and risk-taking each are associated with early alcohol use. In this research, the association of the interaction of risk-taking and impulsivity with early alcohol initiation ... Read more >>

J Adolesc (Journal of adolescence)
[2014, 37(8):1253-1256]

Cited: 7 times

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Environmental enrichment attenuates nicotine behavioral sensitization in male and female rats.

Kristen R Hamilton, Brenda M Elliott, Sarah Shafer Berger, Neil E Grunberg,

Environmental enrichment decreases nicotine reactivity in male rats, but these effects have not been examined in females. This research was conducted to examine the effects of enrichment on nicotine behavioral sensitization (i.e., nicotine reactivity) in male and female rats. One hundred forty-four Sprague-Dawley rats (72 male, 72 female) were raised ... Read more >>

Exp Clin Psychopharmacol (Experimental and clinical psychopharmacology)
[2014, 22(4):356-363]

Cited: 4 times

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Lewis rats have greater response impulsivity than Fischer rats.

Kristen R Hamilton, Marc N Potenza, Neil E Grunberg,

Impulsivity, a tendency toward immediate action without consideration of future consequences, is associated with a wide array of problematic behaviors. Response impulsivity, a type of behaviorally-assessed impulsivity characterized by behavioral disinhibition, is also associated with health risk behaviors. Response impulsivity is distinct from choice impulsivity, which is characterized by intolerance ... Read more >>

Addict Behav (Addictive behaviors)
[2014, 39(11):1565-1572]

Cited: 9 times

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Self-reported impulsivity, but not behavioral approach or inhibition, mediates the relationship between stress and self-control.

Kristen R Hamilton, Rajita Sinha, Marc N Potenza,

Stress has been associated with poor self-control. Individual differences in impulsivity and other behavioral tendencies may influence the relationship of stress with self-control, although this possibility has not been examined to date. The present research investigated whether cumulative stress is associated with poor self-control, and whether this relationship is mediated ... Read more >>

Addict Behav (Addictive behaviors)
[2014, 39(11):1557-1564]

Cited: 7 times

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Nicotine behavioral sensitization in Lewis and Fischer male rats.

Kristen R Hamilton, Amy K Starosciak, Angela Chwa, Neil E Grunberg,

Individuals with greater nicotine-reactivity may be more likely to initiate and maintain cigarette-smoking behavior than individuals with less nicotine-reactivity. In rats, behavioral sensitization reflects a progressive increase in the psychomotor response to drugs of abuse thought to result from neuroplasticity in brain regions that mediate their motivational effects. Studying nicotine ... Read more >>

Exp Clin Psychopharmacol (Experimental and clinical psychopharmacology)
[2012, 20(5):345-351]

Cited: 4 times

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Self-reported impulsivity, but not behavioral choice or response impulsivity, partially mediates the effect of stress on drinking behavior.

Kristen R Hamilton, Emily B Ansell, Brady Reynolds, Marc N Potenza, Rajita Sinha,

Stress and impulsivity contribute to alcohol use, and stress may also act via impulsivity to increase drinking behavior. Impulsivity represents a multi-faceted construct and self-report and behavioral assessments may effectively capture distinct clinically relevant factors. The present research investigated whether aspects of impulsivity mediate the effect of stress on alcohol ... Read more >>

Stress (Stress (Amsterdam, Netherlands))
[2013, 16(1):3-15]

Cited: 14 times

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Hazardous drinking and dimensions of impulsivity, behavioral approach, and inhibition in adult men and women.

Kristen R Hamilton, Rajita Sinha, Marc N Potenza,

Hazardous drinking is characterized by decisions to engage in excessive or risky patterns of alcohol consumption. Levels of impulsivity and behavioral approach and inhibition may differ in hazardous drinkers and nonhazardous drinkers. A comparison of the relative levels of dimensions of impulsivity and behavioral inhibition and approach in adult men ... Read more >>

Alcohol Clin Exp Res (Alcoholism, clinical and experimental research)
[2012, 36(6):958-966]

Cited: 15 times

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Relations among delay discounting, addictions, and money mismanagement: implications and future directions.

Kristen R Hamilton, Marc N Potenza,

Delay discounting is a reduction in the subjective value of a delayed outcome. Elevated delay discounting is a type of impulsivity that is associated with harmful behaviors, including substance abuse and financial mismanagement.Elevated delay discounting as related to addiction and financial mismanagement was reviewed from psychological, neurobiological, and behavioral economic ... Read more >>

Am J Drug Alcohol Abuse (The American journal of drug and alcohol abuse)
[2012, 38(1):30-42]

Cited: 19 times

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Behavioral effects of nicotine withdrawal differ by genetic strain in male and female adolescent rats.

Kristen R Hamilton, Michael E Perry, Sarah Shafer Berger, Neil E Grunberg,

INTRODUCTION: Gender and ethnicity are powerful predictors of initiation and maintenance of cigarette smoking in adults but less is known about their role in smoking in adolescents. Consistent with human studies, rat models also reveal sex and strain differences in response to nicotine administration. METHODS: This research examined nicotine withdrawal ... Read more >>

Nicotine Tob. Res. (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco)
[2010, 12(12):1236-1245]

Cited: 11 times

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Behavioral effects of nicotine withdrawal in adult male and female rats.

Kristen R Hamilton, Sarah Shafer Berger, Michael E Perry, Neil E Grunberg,

Nicotine withdrawal may differ between men and women but clinical reports are inconsistent. Two experiments were conducted to examine behavioral effects of nicotine withdrawal in male and female adult rats in dimly-lit and brightly-lit environments. Ninety-six Sprague-Dawley male and female rats received 7 days continuous subcutaneous infusion via ALZET osmotic ... Read more >>

Pharmacol. Biochem. Behav. (Pharmacology, biochemistry, and behavior)
[2009, 92(1):51-59]

Cited: 17 times

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