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Author Kiyoshi Ito

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Tailor-made Endoscopic Surgical Strategy for Severe Intraventricular Hemorrhage with Obstructive Hydrocephalus.

Toshihiro Ogiwara, Yota Suzuki, Takatoshi Hasegawa, Takuya Nakamura, Yu Fujii, Yoshiki Hanaoka, Kiyoshi Ito, Akifumi Yokota, Fumiko Higashiyama, Fusakazu Oya, Tetsuyoshi Horiuchi,

<h4>Background</h4>Severe intraventricular hemorrhage (IVH) is associated with high mortality rate and poor functional outcome, even with recent neurosurgical developments. This pathology requires emergent surgery to save the patient's life, but the optimal surgical strategy remains controversial. Here, we assess the results obtained with our tailor-made endoscopic surgical strategy for severe ... Read more >>

World Neurosurg (World neurosurgery)
[2021, :]

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The first-round results of a population-based cohort study of HPV testing in Japanese cervical cancer screening: baseline characteristics, screening results, and referral rate.

Kanako Kono, Tohru Morisada, Kumiko Saika, Eiko Saitoh Aoki, Etsuko Miyagi, Kiyoshi Ito, Hirokazu Takahashi, Tomio Nakayama, Hiroshi Saito, Daisuke Aoki,

<h4>Objective</h4>In 2013, a cohort study aimed to clarify the positive and negative effects of introducing the human papillomavirus (HPV) testing for population-based cervical cancer screening has been launched in Japan. This study included four screenings during the subsequent 7-year follow-up period. We aim to describe the results of the first ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(3):e29]

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Mental Health and Physical Activity among Children and Adolescents during the COVID-19 Pandemic.

Junko Okuyama, Shuji Seto, Yu Fukuda, Shunichi Funakoshi, Shintaro Amae, Jun Onobe, Shinichi Izumi, Kiyoshi Ito, Fumihiko Imamura,

Coronavirus disease 2019 (COVID-19) is causing disruptions in the global social system. Japanese children and adolescents have had their schools closed, government-mandated activity restrictions imposed, and interactions outside the home reduced. These restrictions can have a considerable psychological impact on children and adolescents. This review aims to describe the impacts ... Read more >>

Tohoku J Exp Med (The Tohoku journal of experimental medicine)
[2021, 253(3):203-215]

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Endoscopic Endonasal Approach in the Smart Cyber Operating Theater (SCOT): Preliminary Clinical Application.

Toshihiro Ogiwara, Tetsuya Goto, Yu Fujii, Takuya Nakamura, Yota Suzuki, Yoshiki Hanaoka, Kiyoshi Ito, Tetsuyoshi Horiuchi, Kazuhiro Hongo,

<h4>Background</h4>A next-generation networked operating room, Smart Cyber Operating Theater (SCOT), has been developed in cooperation with medical engineers that integrates standalone medical devices, including intraoperative magnetic resonance imaging (MRI) using the OPeLiNK communication interface. Here, we report the application of this newly developed advanced type of operating theater for the ... Read more >>

World Neurosurg (World neurosurgery)
[2021, 147:e533-e537]

Cited: 1 time

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T-Configuration Stent Placement for Carotid Bifurcation Stenosis Co-Existing with Ipsilateral Intracranial Stenosis: A Case Report and Literature Review.

Yuki Kubota, Yoshiki Hanaoka, Jun-Ichi Koyama, Yu Fujii, Toshihiro Ogiwara, Kiyoshi Ito, Tetsuyoshi Horiuchi,

In patients with carotid bifurcation stenosis co-existing with ipsilateral intracranial artery stenosis, combined treatment with carotid artery stenting (CAS)/carotid endarterectomy (CEA) and extracranial-to- intracranial (EC-IC) bypass can be a useful option to prevent future ischemic stroke events. EC-IC bypass requires a sufficient antegrade flow in the ipsilateral external carotid artery. ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2021, 30(2):105472]

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Bilateral Transradial Approach for Coil Embolization of Basilar Artery Aneurysms Associated with an Unfavorable Vertebral Artery Anatomy : Initial Experience with Role-sharing Technique.

Yoshiki Hanaoka, Jun-Ichi Koyama, Yu Fujii, Toshihiro Ogiwara, Kiyoshi Ito, Tetsuyoshi Horiuchi,

<h4>Purpose</h4>An unfavorable vertebral artery (VA) anatomy occasionally inhibits a successful VA cannulation due to flow stagnation after catheterization. To preserve antegrade VA flow, we developed bilateral transradial catheter systems, referred to as the role-sharing technique, for coil embolization of basilar artery (BA) aneurysms associated with an unfavorable VA anatomy. This study ... Read more >>

Clin Neuroradiol (Clinical neuroradiology)
[2020, :]

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Impact of COVID-19 restrictions on the research environment and motivation of researchers in Japan

Yasuhiro Miki, Natsuko Chubachi, Fumihiko Imamura, Nobuo Yaegashi, Kiyoshi Ito,

The environment surrounding researchers has changed significantly in the face of COVID-19 restrictions. An online self-reported questionnaire was completed by 10,557 participants between June 15 and 19, 2020. The impact on work/research activities and harassments under COVID-19 conditions was higher among researchers (1963) compared to non-researchers (8572). We further examined ... Read more >>

(Progress in Disaster Science)
[2020, 8:100128-100128]

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Assessment of collateral venous flow using temporary clip placement at ICG videoangiography.

Ridzky Firmansyah Hardian, Yoshiki Hanaoka, Kohei Funato, Masahiro Agata, Kiyoshi Ito, Tetsuyoshi Horiuchi,

<h4>Background</h4>As there are many collateral pathways between venous systems, intraoperative venous injury rarely induces venous infarction. In some patients, however, venous injury during microsurgical manipulation may cause acute and/or delayed serious complications. Although intraoperative evaluation using indocyanine green (ICG) videoangiography is very useful, it is difficult to assess the flow ... Read more >>

Acta Neurochir (Wien) (Acta neurochirurgica)
[2020, :]

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Alteration of BAFF and APRIL in the cerebrospinal fluid based on the therapeutic response in primary central nervous system B-cell lymphoma.

Junji Ikeda, Yasuhiro Shimojima, Tsuneaki Yoshinaga, Minori Kodaira, Sayaka Nishina, Kiyoshi Ito, Yoshiki Sekijima,

We evaluated the cerebrospinal fluid (CSF) levels of the B-cell activating factor of the tumor necrosis factor family (BAFF) and A proliferation-inducing ligand (APRIL) in two cases of primary central nervous system B-cell lymphoma (PCNSBL) before and after treatment. One patient achieved clinical remission, and demonstrated decrease in the CSF ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2020, 81:72-75]

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Treatment Strategy for Giant Invasive Macroprolactinoma with Spontaneous Cerebrospinal Fluid Rhinorrhea: A Case Report and Literature Review.

Daishiro Abe, Toshihiro Ogiwara, Takuya Nakamura, Shunsuke Ichinose, Yu Fujii, Yoshiki Hanaoka, Kiyoshi Ito, Tetsuyoshi Horiuchi,

<h4>Background</h4>Spontaneous cerebrospinal fluid (CSF) rhinorrhea associated with untreated prolactinomas is rare, which is in contrast to medical treatment-induced CSF rhinorrhea. Previous studies have suggested that cessation of drug administration should be the first line of treatment for prolactinoma with medically induced CSF rhinorrhea. On the other hand, there is no ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 144:19-23]

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Feasibility and Safety of Radial-First Approach with a Radial-Specific Neurointerventional Guiding Sheath for Intracranial Aneurysm Coiling in the Anterior Circulation.

Yoshiki Hanaoka, Jun-Ichi Koyama, Toshihiro Ogiwara, Yu Fujii, Kiyoshi Ito, Tetsuyoshi Horiuchi,

<h4>Background</h4>In cardiac intervention, the transradial approach (TRA) is increasingly used as the first-line approach owing to numerous advantages over the transfemoral approach. Neurointerventional TRA, especially in intracranial interventions, is predominantly restricted to an alternative approach, as transradial carotid cannulation using a conventional transfemoral system can be technically challenging for patients ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 142:e297-e306]

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Passability and Impassability of Microcatheters Through the Neuroform Atlas Stent During the Trans-cell Approach: An Experimental Evaluation.

Yoshiki Hanaoka, Jun-Ichi Koyama, Daisuke Yamazaki, Toshihiro Ogiwara, Kiyoshi Ito, Tetsuyoshi Horiuchi,

<h4>Background</h4>Trans-cell approach for the Neuroform Atlas stent (Stryker Neurovascular, Fremont, CA) is occasionally unsuccessful as a microcatheter can become stuck in the struts. This study aimed to evaluate the passability and impassability of 0.0165-inch microcatheters through the Neuroform Atlas stent using a simplified benchtop model.<h4>Methods</h4>The distal struts of the target ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 141:e474-e483]

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Cauda equina biopsy as a tool in the diagnosis of malignant tumors.

Kiyoshi Ito, Takuya Nakamura, Tetsuyoshi Horiuchi, Uehara Takeshi,

The prevalence of malignant lymphoma is increasing. With the advent of novel therapeutic approaches, the distinct pathology of each type of malignant lymphoma is used to tailor its treatment for the most effective outcome. Therefore, analysis of the malignant cell pathophysiology within the cauda equina is important to devising a ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2020, 77:207-210]

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<Editors' Choice> Initial experience with in vivo "endovascular shaping" technique that utilizes the vascular configuration for small cerebral aneurysm coiling.

Yoshiki Hanaoka, Jun-Ichi Koyama, Daisuke Yamazaki, Yoshinari Miyaoka, Yu Fujii, Takuya Nakamura, Toshihiro Ogiwara, Kiyoshi Ito, Tetsuyoshi Horiuchi,

Optimal shaping of a microcatheter tip is a key factor in cerebral aneurysm coiling. However, safe cannulation and stabilization of a microcatheter can be technically challenging with small aneurysms requiring precise microcatheter shaping. We devised a new microcatheter shaping technique which bends a microcatheter tip in the intended direction by ... Read more >>

Nagoya J Med Sci (Nagoya journal of medical science)
[2020, 82(2):355-362]

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[Application of Robotics to Spinal Surgery].

Kiyoshi Ito, Takuya Nakamura, Tetsuyoshi Horiuchi,

No Shinkei Geka (No shinkei geka. Neurological surgery)
[2020, 48(5):385-395]

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Posterior spinal fusion for severe kyphoscoliosis in a Loeys-Dietz syndrome patient with a large syringomyelia.

Masashi Uehara, Kiyoshi Ito, Tomoki Kosho, Shugo Kuraishi, Hiroki Oba, Terue Hatakenaka, Shota Ikegami, Takashi Takizawa, Ryo Munakata, Motoo Kubota, Jun Takahashi,

Spinal deformity is a characteristic feature of Loeys-Dietz syndrome (LDS). Surgical correction in LDS is indicated when the deformity is progressive to avoid neurological deficits, respiratory impairment, and back pain. However, few reports exist on the surgical treatment of spinal deformity in LDS, and no therapeutic standards have been established. ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2020, 76:211-213]

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Microanatomy of the dura mater at the craniovertebral junction and spinal region for safe and effective surgical treatment.

Kiyoshi Ito, Mitsunori Yamada, Tetsuyoshi Horiuchi, Kazuhiro Hongo,

OBJECTIVE:Few reports have been published regarding the detailed microsurgical anatomy of the dura mater at the craniovertebral junction (CVJ), although many neurosurgeons have had the opportunity to conduct surgeries in this region, such as in cases of Chiari malformation. The authors aimed to evaluate the detailed and precise microsurgical anatomy ... Read more >>

J Neurosurg Spine (Journal of neurosurgery. Spine)
[2020, :1-7]

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Cervical cancer screening rates before and after the Great East Japan Earthquake in the Miyagi Prefecture, Japan.

Yasuhiro Miki, Toru Tase, Hideki Tokunaga, Nobuo Yaegashi, Kiyoshi Ito,

After disasters, issues pertaining to women's health such as irregular periods and bleeding are well surveyed. However, the management of women's health, especially changes in the rate of health checkups, has not been investigated. In the present study, we focused on the change in the cervical cancer screening rates (CCS-Rs) ... Read more >>

PLoS One (PloS one)
[2020, 15(3):e0229924]

Cited: 1 time

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Transradial Approach as the Primary Vascular Access with a 6-Fr Simmons Guiding Sheath for Anterior Circulation Interventions: A Single-Center Case Series of 130 Consecutive Patients.

Yoshiki Hanaoka, Jun-Ichi Koyama, Daisuke Yamazaki, Yoshinari Miyaoka, Yu Fujii, Takuya Nakamura, Toshihiro Ogiwara, Kiyoshi Ito, Tetsuyoshi Horiuchi,

OBJECTIVE:In coronary intervention, the transradial approach (TRA) is increasingly used as the primary vascular access because of its numerous advantages over the transfemoral approach. However, in neurointerventions, conventional TRA with a straight-shaped guiding system is used as an alternative vascular access because transradial carotid cannulation can be technically challenging for ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 138:e597-e606]

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Divergent metabolic responses dictate vulnerability to NAMPT inhibition in ovarian cancer.

Kei Kudo, Miyuki Nomura, Yoshimi Sakamoto, Shigemi Ito, Mami Morita, Masaaki Kawai, Yoji Yamashita, Kiyoshi Ito, Hidekazu Yamada, Hiroshi Shima, Nobuo Yaegashi, Nobuhiro Tanuma,

It is of current interest to target cancer metabolism as treatment for many malignancies, including ovarian cancer (OVC), in which few druggable driver mutations have been identified. Nicotinamide phosphoribosyltransferase (NAMPT), a rate-limiting enzyme in the NAD salvage pathway, is a potential therapeutic target in OVC. However, factors that determine responsiveness ... Read more >>

FEBS Lett (FEBS letters)
[2020, 594(9):1379-1388]

Cited: 1 time

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Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective.

Shinichi Kuriyama, Hirohito Metoki, Masahiro Kikuya, Taku Obara, Mami Ishikuro, Chizuru Yamanaka, Masato Nagai, Hiroko Matsubara, Tomoko Kobayashi, Junichi Sugawara, Gen Tamiya, Atsushi Hozawa, Naoki Nakaya, Naho Tsuchiya, Tomohiro Nakamura, Akira Narita, Mana Kogure, Takumi Hirata, Ichiro Tsuji, Fuji Nagami, Nobuo Fuse, Tomohiko Arai, Yoshio Kawaguchi, Shinichi Higuchi, Masaki Sakaida, Yoichi Suzuki, Noriko Osumi, Keiko Nakayama, Kiyoshi Ito, Shinichi Egawa, Koichi Chida, Eiichi Kodama, Hideyasu Kiyomoto, Tadashi Ishii, Akito Tsuboi, Hiroaki Tomita, Yasuyuki Taki, Hiroshi Kawame, Kichiya Suzuki, Naoto Ishii, Soichi Ogishima, Satoshi Mizuno, Takako Takai-Igarashi, Naoko Minegishi, Jun Yasuda, Kazuhiko Igarashi, Ritsuko Shimizu, Masao Nagasaki, Osamu Tanabe, Seizo Koshiba, Hiroaki Hashizume, Hozumi Motohashi, Teiji Tominaga, Sadayoshi Ito, Kozo Tanno, Kiyomi Sakata, Atsushi Shimizu, Jiro Hitomi, Makoto Sasaki, Kengo Kinoshita, Hiroshi Tanaka, Tadao Kobayashi, , Shigeo Kure, Nobuo Yaegashi, Masayuki Yamamoto,

Int J Epidemiol (International journal of epidemiology)
[2020, 49(1):18-19m]

Cited: 7 times

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A comparison of liquid-based and conventional cytology using data for cervical cancer screening from the Japan Cancer Society.

Kiyoshi Ito, Ryusei Kimura, Hiroshi Konishi, Nobuyoshi Ozawa, Nobuo Yaegashi, Yasuo Ohashi, Mitsuaki Suzuki, Tadao Kakizoe,

<h4>Objective</h4>Liquid-based cytology has replaced conventional cytology in cervical cancer screening in many countries. However, a detailed comparison of liquid-based cytology with conventional cytology has not been reported in Japan. Therefore, the aim of the study is to evaluate efficacy of liquid-based cytology in Japan.<h4>Methods</h4>We first evaluated the prevalence of use ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2020, 50(2):138-144]

Cited: 1 time

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Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study.

Atsushi Hozawa, Kozo Tanno, Naoki Nakaya, Tomohiro Nakamura, Naho Tsuchiya, Takumi Hirata, Akira Narita, Mana Kogure, Kotaro Nochioka, Ryohei Sasaki, Nobuyuki Takanashi, Kotaro Otsuka, Kiyomi Sakata, Shinichi Kuriyama, Masahiro Kikuya, Osamu Tanabe, Junichi Sugawara, Kichiya Suzuki, Yoichi Suzuki, Eiichi N Kodama, Nobuo Fuse, Hideyasu Kiyomoto, Hiroaki Tomita, Akira Uruno, Yohei Hamanaka, Hirohito Metoki, Mami Ishikuro, Taku Obara, Tomoko Kobayashi, Kazuyuki Kitatani, Takako Takai-Igarashi, Soichi Ogishima, Mamoru Satoh, Hideki Ohmomo, Akito Tsuboi, Shinichi Egawa, Tadashi Ishii, Kiyoshi Ito, Sadayoshi Ito, Yasuyuki Taki, Naoko Minegishi, Naoto Ishii, Masao Nagasaki, Kazuhiko Igarashi, Seizo Koshiba, Ritsuko Shimizu, Gen Tamiya, Keiko Nakayama, Hozumi Motohashi, Jun Yasuda, Atsushi Shimizu, Tsuyoshi Hachiya, Yuh Shiwa, Teiji Tominaga, Hiroshi Tanaka, Kotaro Oyama, Ryoichi Tanaka, Hiroshi Kawame, Akimune Fukushima, Yasushi Ishigaki, Tomoharu Tokutomi, Noriko Osumi, Tadao Kobayashi, Fuji Nagami, Hiroaki Hashizume, Tomohiko Arai, Yoshio Kawaguchi, Shinichi Higuchi, Masaki Sakaida, Ryujin Endo, Satoshi Nishizuka, Ichiro Tsuji, Jiro Hitomi, Motoyuki Nakamura, Kuniaki Ogasawara, Nobuo Yaegashi, Kengo Kinoshita, Shigeo Kure, Akio Sakai, Seiichiro Kobayashi, Kenji Sobue, Makoto Sasaki, Masayuki Yamamoto,

<h4>Background</h4>We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular diseases.<h4>Methods</h4>We asked participants to join our cohort in the health check-up settings and assessment center based ... Read more >>

J Epidemiol (Journal of epidemiology)
[2021, 31(1):65-76]

Cited: 4 times

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Synthesis of Small Fluorescent Molecules and Evaluation of Photophysical Properties.

Futa Ogawa, Yukiko Karuo, Ryuji Yamazawa, Kanae Miyanaga, Kazushige Hori, Keita Tani, Kengo Yamada, Yuki Saito, Kazumasa Funabiki, Atsushi Tarui, Kazuyuki Sato, Kiyoshi Ito, Kentaro Kawai, Masaaki Omote,

A series of aniline-based fluorophores were newly synthesized. To increase their fluorescence quantum yields, it was particularly important to substitute 3,3,3-trifluoroprop-1-enyl (TFPE) groups next to the amino group to benefit from an extended π-electron delocalization. Among these, 5-CN-2-TFPE-aniline was found to behave as an excellent fluorophore with a reasonable fluorescence ... Read more >>

J Org Chem (The Journal of organic chemistry)
[2020, 85(2):1253-1258]

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Endoscopic Endonasal Odontoidectomy in the Hybrid Operating Room.

Toshihiro Ogiwara, Yoshinari Miyaoka, Takuya Nakamura, Keita Tsukada, Daisuke Yamazaki, Kiyoshi Ito, Yoshiki Hanaoka, Jun-Ichi Koyama, Tetsuyoshi Horiuchi, Kazuhiro Hongo,

<h4>Background</h4>The endoscopic endonasal approach for the craniovertebral junction (CVJ), instead of the microscopic transoral approach, has been widely adopted and accepted, especially in resection of the odontoid process for basilar invagination. However, there is concern regarding insufficient resection of odontoid and surgical complications, including vessel injuries, because this is a ... Read more >>

World Neurosurg (World neurosurgery)
[2019, 131:137-140]

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