Full Text Journal Articles by
Author Khan Usmanghani

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Chewable cough tablets with improved palatability: A comparative phase II clinical trial.

Mehwish Khan, Hina Rehman, Safila Naveed, Syed Faisal Zaidi, Sultan Ayaz, Aymen Owais, Khan Usmanghani,

Cough is the common disease condition which affects patients of every age. Numerous OTC medications available in community pharmacies however no antiviral treatment and even antibiotics has been shown to be effective without pre-existing lung infection. The treatment approach of medicinal herbs has been recognized for many decades and even ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(1(Supplementary)):339-343]

Cited: 1 time

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Phytochemical standardization of Vasicinein cough syrup by high performance liquid chromatography-densitometry.

Hina Rehman, Safila Naveed, Fatima Qamar, Sultan Ayaz, Sadia Jamil, Sakina Fatima, Aisha Sana, Khan Usmanghani,

The highly oriented modern detection techniques provide a precise and definite tool for investigation in natural medicines. Current study directed the standardization of eminent biomarker Vasicine in a natural cough syrup. A highly accurate and precise method of High-performance thin layer chromatography (HPTLC) has been developed to certify the quantity ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(6 (Supplementary):2679-2682]

Cited: 0 times

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The evaluation ofefficacy and safety of Cough (EMA) granules used for upper respiratory disorders.

Muhammad Faizan Khan, Muhammad Akram, Naheed Akhter, Muhammad Mukhtiar, Rabia Zahid, Fahad Said Khan, Muhammad Daniyal, Imtiaz Mahmood Tahir, Khalil Ahmed, Aamir Sharif, Shamaila Kausar, Syed Muhammad Ali Shah, Khan Usmanghani,

Ivy leaf is used for the treatment of respiratory diseases with the intensive mucus formation, respiratory infections, and irritating cough coming from the common cold. Conferring to clinical trials, the efficacy, and tolerability of ivy leaf is good. The main compounds accountable for biological activity are triterpene and saponins. Ivy ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(6 (Supplementary):2617-2622]

Cited: 1 time

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Evaluation of in vitro antioxidant capacity and reducing potential of polyherbal Coded capsules Arthitec 1 and Arthitec 2.

Ejaz Basheer, Sadia Shakeel, Kashif Sohail, Muhammad Qaiser, Khan Usmanghani,

Free radicals are partially reduced form of metabolites of Nitrogen and Oxygen. These are highly reactive and potentially toxic compounds which are contributing factors in different chronic disease. The present study was aimed to determine antioxidant capability and reducing ability of coded polyherbal capsules (Arthitec 1 & Arthitec 2). DPPH ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(6 (Supplementary):2635-2638]

Cited: 0 times

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To evaluate the efficacy and safety of CartiNovex plus tablet in osteoarthritis and rheumatoid arthritis.

Amir Riaz, Muhammad Daniyal, Muhammad Ishaq Ghauri, Hamza Alam, Syed Faisal Zaidi, Khan Usmanghani, Wei Wang,

Interminable arthritis issue, for example, osteoarthritis (OA) and rheumatoid arthritis (RA) have in like manner an upsurge of aggravation, and oxidative anxiety, bringing about dynamic histological modifications and incapacitating indications. As of now utilized allopathic prescription (extending from painkiller executioners to natural operators) is intense, yet regularly connected with genuine, ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(5(Supplementary)):2033-2040]

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Pharmaceutical equivalent dissertation of Metformin hydrochloride brands.

Safila Naveed, Huma Dilshad, Maheen Nafees, Muhammad Ibrar Shinwari, Khan Usmanghani, Ghulam Sarwar,

The aim of study is to establish pharmaceutical equivalence of different brands of Metformin tablets available in Karachi, Pakistan. The quality control parameters which are studied are weight variation test, hardness test, thickness, friability, disintegration and dissolution specified by BP/USP (British and United State Pharmacopoeia). Weight variation and hardness value ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(1):69-73]

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Estimation of simvastatin and cetirizine by RP-LC method: Application to freeze and thaw (FT) stability studies.

Safila Naveed, Khan Usmanghani, Aisha Sana, Huma Ali, Farya Zafar, Fatima Qamar, Ghulam Sarwer, Sarah Abbas, M Tanweer Alam, Muhammad Ibrar Shinwari,

Sensitive, simple, reliable and rapid HPLC technique for the estimation of simvastatin (SMV) and cetirizine has been designed in this study. The chromatographic conditions were set using Shimadzu LC-10 AT VP pump, with UV detector (SPD-10 AV-VP). System integration was performed with CBM-102 (Bus Module). Partitioning of components was attained ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(1):137-141]

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A randomized, control and comparative study of polyherbal formulation use for Malaria (Plasmodium falciparum).

Khan Muhammad Baloch, Khan Usmanghani, Ejaz Mohiuddin, Tasneem Qureshi, Muhammad Daniyal, Muhammad Ibrar Shinwari,

Plasmodium falciparum is the most well-known reason for extreme and life-debilitating malaria. Falciparum malaria causes more than 1 million deaths annually. Malaria remains a noteworthy reason for major morbidity and mortality in the tropics, with Plasmodium falciparum accountable for the mainstream of the disease weight and Plasmodium vivax being the ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2018, 31(1(Suppl.)):291-297]

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Can Diet Modulate Helicobacter pylori-associated Gastric Pathogenesis? An Evidence-Based Analysis.

Syed Faisal Zaidi, Kanwal Ahmed, Sheikh Abdul Saeed, Usmanghani Khan, Toshiro Sugiyama,

Helicobacter pylori is involved in the pathogenesis of gastritis, peptic ulcer, and gastric cancer. The infection is prevalent in more than half of the world's population. Although the infection may lead to detrimental consequences, still the majority of the infected individuals only develop mild gastritis. Several factors are behind this ... Read more >>

Nutr Cancer (Nutrition and cancer)
[2017, 69(7):979-989]

Cited: 2 times

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An interquartile relationship between polyherbal extract based lozenges linkus a phase IV comparative randomised control trial.

Hina Rehman, Syed Adnan Ali, Safila Naveed, Khan Usmanghani,

The aim of the study is to determine the efficacy of polyherbal linkus with the other pharmaceutical marketed syrup having Acefyllin Piperazine, Diphenhydramine group and Aminophylline Diphenhydramine group on the basis of interquartile ranges on children. It was open label multi centric randomize control trial. The study was conducted on ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2017, 30(3(Suppl.)):961-966]

Cited: 0 times

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To evaluate the efficacy and safety of CofNovex plus (EMA) syrup.

Zubair Ali, Muhammad Daniyal, Muhammad Khalid Adhia, Anees Alam, Babar Sarfaraz, Abdul Sattar, Khan Usmanghani,

The cough and cold are very widespread conditions and a common purpose for advice in general practice. Utmost often the sign and symptoms of cough are produced by acute viral airway infection and the course is frequently benign. But it can be converted into bacterial super-infection and can cause acute ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2017, 30(2(Suppl.)):591-596]

Cited: 1 time

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Alternative treatment in Hepatitis B by using polyherbal formulation.

Omar Iqbal, Halima Nazar, Samina Afzal, Khan Usmanghani,

The hepatitis B is most prevalent diseases (along with morbidities) in Asian countries. This research study has been conducted to provide an alternative treatment which is safe, effective and cost-effective to comprehend relations of disease, symptoms, patients response and the clinical response via better management of hepatitis B. The goal ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2017, 30(1):49-54]

Cited: 0 times

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Antipyretic potential of herbal coded formulation (Pyrexol).

Muhammad Sajid Khan, Abdul Hamid, Muhammad Akram, Sodah Bint Mustafa, Abdul Sami, Syed Muhammad Ali Shah, Khan Usmanghani,

The antipyretic effect of the aqueous extract of herbal coded formulation containing equal amount of Salix alba, Emblica officinalis, Glycyrrhiza glabra, Adhatoda vasica, Viola odorata, Thea sinensis, Veleriana officinalis, Foeniculum vulgare, Sisymbrium irrio and Achillea millefolium was investigated using the yeast induced pyrexia model in rabbits. Paracetamol was used as ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2017, 30(1):195-198]

Cited: 0 times

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Efficacy of Gingocap as compared to pyridoxine in the treatment of nausea and vomiting during pregnancy.

Lala Rukh, Halima Nazar, Khan Usmanghani,

Nausea and vomiting is the common problem disturbing almost 80% of the females in initial three months of conception and later sometime throughout pregnancy. To find out the efficacy and safety of herbal coded test drug Gingocap in comparison with the control drug Pyridoxine, a randomized clinical case control study ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(6):1937-1943]

Cited: 1 time

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Comparison of Anti BPH capsule (herbal) and Terazosin HCl in the treatment of benign prostate hyperplasia.

Hafiz Mohammad Rashid Nadeem, Ejaz Mohiuddin, Shahab UdDin, Muhammad Daniyal, Khan Usmanghani,

Benign prostatic hyperplasia (BPH) is a disease of senile age, usually occurring> 60 years of age. BPH is a disease that involves cell proliferation of the prostate. Pathological hyperplasia affects the elements of the glandular and connective tissue of the prostate. This study is designed to scrutinize the efficacy and ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2017, 30(1 Suppl):289-293]

Cited: 0 times

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Efficacy and safety of Entoban for the treatment of chronic diarrhea.

Sadia Shakeel, Khan Usmanghani, Hafiz Muhammad Asif,

The current randomized clinical trial was conducted to assess the safety and effectiveness of Entoban for treating patients of chronic diarrhea. The study enrolled 150 patients fulfilling the inclusion criteria, among them 95 were males and 55 were females. Written informed consent was obtained from all study participants. Metronidazole tablets ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(6 Suppl):2349-2353]

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Clinical efficacy and safety of herbal medicine Dermidoc in the management of atopic dermatitis versus allopathic medicine PolymixinB-bacitrin ointment.

Muhammad Osama Alam, Ejaz Mohiuddin, - Shahab-Ud-Din, Muhammad Daniyal, Khan Usmanghani,

Atopic dermatitis (AD) commonly identified as eczema. AD is an inflammatory, long-lasting, highly pruritic reverting disease of the skin. AD is classified by disease of outer skin layer barrier function. AD is progress with Immunoglobulin E facilitated sensitization to food and environmental allergens. One study stated that more than 59.6% ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(6 Suppl):2287-2291]

Cited: 0 times

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In vitro antioxidant and reducing capability of weight loss tablet formulation.

Syed RashidAli Jaffary, Syed Waseemuddin Ahmed, Sadia Shakeel, Hafiz Muhammad Asif, Khan Usmanghani,

Antioxidants are used as an influential counteractive measure in opposing the generation of reactive oxygen species. The current study was carried out to investigate antioxidant potential and reducing capability of developed weight reducing tablet formulation. When tablets were evaluated at concentrations of 50, 100 and 500μ/ml, antioxidant activity improved in ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(5 Suppl):1749-1753]

Cited: 0 times

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Clinical study on the efficacy of Amoebex (coded herbal drug) compared with Metronidazole for the treatment of Amoebic dysentery.

Syed MuhammadAli Shah, Khan Usmanghani, Naveed Akhtar, Muhammad Akram, Hafiz Muhammad Asif, Muhammad Mohtasheemul Hasan,

Amoebiasisis an infectious disease, which originated with the single-celled parasitic protozoan Entamoeba histolytica. The parasitic amoeba infects the liver and intestine and may cause mild diarrhea and serious dysentery with bloody and mucoid stool. A study was conducted to evaluate the efficacy of Amoebex (400mg), a herbal formulation for the ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(6):2005-2014]

Cited: 2 times

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Review-Medicinal plants and management of Diabetes Mellitus: A review.

Sodah Bint Mustafa, Zahid Mehmood, Naheed Akhter, Abida Kauser, Iqbal Hussain, Abid Rashid, Muhammad Akram, Imtiaz Mahmood Tahir, Naveed Munir, Muhammad Riaz, Samia Gul Niazi, Abid Ali, Muhammad Mudassar Ashraf, Umbreen Naz, Hammad Ahmed, S M Ali Shah, Khan Usmanghani,

Diabetes is a metabolic disorder characterized by chronic hyperglycemia and associated with dysfunction and failure of various body organs. Alarming increase in prevalence rate has made this disorder a major health problem globally. The available treatment modalities are not sufficient to combat diabetes and associated complications. A number of medicinal ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(5 Suppl):1885-1891]

Cited: 2 times

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Evaluation of in vitro urease and lipoxygenase inhibition activity of weight reducing tablets.

Syed Rashid Ali Jaffary, Syed Waseemuddin Ahmed, Sadia Shakeel, Hafiz Muhammad Asif, Khan Usmanghani,

Enzyme inhibition is a significant part of research in pharmaceutical field in view of the fact that these studies have directed to the innovations of drugs having remarkable performance in diverse physiological conditions. The present study was aimed to assess urease and lipoxygenase inhibitory activity of weight reducing tablets. For ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(4 Suppl):1397-1400]

Cited: 0 times

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Effect of hormonal contraceptives on serum lipids: A prospective study.

Huma Dilshad, Rabia Ismail, Safila Naveed, Khan Usmanghani, M Tanweer Alam, Ghulam Sarwar,

To estimate the effects of using hormonal contraceptives on serum lipoprotein levels. Lipid profile was measured at baseline and afterward at 3, 6, 9 and 12 months. 1391 Pakistani females taking COCs, DMPA, or non hormonal (NH) contraceptives. The results were calculated by repeated measure ANOVA subsequent to tukey's post ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(4 Suppl):1379-1382]

Cited: 2 times

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Review: Comprehensive review on treatment of HIV.

Muhammad Daniyal, Muhammad Akram, Abdul Hamid, Allah Nawaz, Khan Usmanghani, Saeed Ahmed, Leena Hameed,

HIV or AIDS is a major threat for humanity in the world especially in developing countries. The causative factor of the syndrome is HIV, which infects and destroys one of the cellular components of the immune system, the T cells, causing deficiency in the immunological surveillance and ultimately leading to ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(4):1331-1338]

Cited: 3 times

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Evaluation, efficacy and tolerability of GlucoNovax tablet in type 2 diabetic patients.

Zubair Ali, Muhammad Daniyal, Ismailov S I, Khan Usmanghani, Safila Naveed,

Type 2 diabetes mellitus (T2D) is a chronic metabolic disease regarded as insulin resistance and progressive failure of β cells. Beta cells secretagogues are useful to reach satisfactory glycemic control. Glimepiride is a second-generation sulfonylurea excites pancreatic beta cells to discharge insulin. Glimepiride may be safer to use in patients ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(4 Suppl):1443-1449]

Cited: 0 times

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Efficacy and safety of Linkus, Aminophylline diphenhydramine and acefyllin piperazine for the treatment of cough in children.

Hina Rehman, Safila Naveed, Khan Usmanghani,

To evaluate the safety and efficacy of Linkus, Aminophylline with Diphenhydramine group and Acefyllin Piperazine with Diphenhydramine cough syrup on children having cough and sleep difficulty associated with cough. To determine the effects of Linkus polyherbal syrup (group A) and compared with other parallel allopathic groups (Group B and C) ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(3 Suppl):1027-1032]

Cited: 0 times

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