Full Text Journal Articles by
Author Kevin T McVary

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Kevin T McVary, Marc C Gittelman, Kenneth A Goldberg, Kalpesh Patel, Neal D Shore, Richard M Levin, Marc Pliskin, J Randolf Beahrs, David Prall, Jed Kaminetsky, Barrett E Cowan, Christopher H Cantrill, Lance A Mynderse, James C Ulchaker, Nicholas N Tadros, Steven N Gange, Claus G Roehrborn,

J Urol (The Journal of urology)
[2021, :101097JU000000000000177803]

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Final 5-Year Outcomes of the Multicenter Randomized Sham-Controlled Trial of a Water Vapor Thermal Therapy for Treatment of Moderate to Severe Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia.

Kevin T McVary, Marc C Gittelman, Kenneth A Goldberg, Kalpesh Patel, Neal D Shore, Richard M Levin, Marc Pliskin, J Randolf Beahrs, David Prall, Jed Kaminetsky, Barrett E Cowan, Christopher H Cantrill, Lance A Mynderse, James C Ulchaker, Nicholas N Tadros, Steven N Gange, Claus G Roehrborn,

<h4>Purpose</h4>We present final 5-year outcomes of the multicenter randomized sham-controlled trial of a water vapor therapy (Rezūm™) for treatment of moderate to severe lower urinary tract symptoms due to benign prostatic hyperplasia.<h4>Materials and methods</h4>A total of 197 subjects <u>></u>50 years of age with International Prostate Symptom Score ≥13, maximum flow ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001778]

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Caspase Signaling in ED Patients and Animal Models.

Sarah Martin, Daniel A Harrington, Samuel Ohlander, Samuel I Stupp, Kevin T McVary, Carol A Podlasek,

<h4>Background</h4>Current treatments for erectile dysfunction (ED) are ineffective in prostatectomy and diabetic patients due to cavernous nerve (CN) injury, which causes smooth muscle apoptosis, penile remodeling, and ED. Apoptosis can occur via the intrinsic (caspase 9) or extrinsic (caspase 8) pathway.<h4>Aim</h4>We examined the mechanism of how apoptosis occurs in ED ... Read more >>

J Sex Med (The journal of sexual medicine)
[2021, 18(4):711-722]

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Putting Patients Ahead by Leaving Nothing Behind: An Emerging Treatment Paradigm in Minimally Invasive Surgical Therapy for Benign Prostatic Hyperplasia.

Kevin T McVary, Bilal Chughtai, Larry E Miller, Samir K Bhattacharyya, Ryan A Dornbier, Dean S Elterman,

Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) are highly prevalent in older men. The long-term clinical utility of lifestyle modification and oral medications for LUTS is limited. There is a great clinical need for safe, effective, and durable BPH therapies for men who unsuccessfully attempt conservative ... Read more >>

Med Devices (Auckl) (Medical devices (Auckland, N.Z.))
[2021, 14:59-64]

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Surgical Reintervention Rate after Prostatic Urethral Lift: Systematic Review and Meta-Analysis Involving over 2,000 Patients. Reply.

Larry E Miller, Bilal Chughtai, Ryan A Dornbier, Kevin T McVary,

J Urol (The Journal of urology)
[2021, 205(3):940-941]

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The rising worldwide impact of benign prostatic hyperplasia.

Bryn M Launer, Kevin T McVary, William A Ricke, Granville L Lloyd,

<h4>Objectives</h4>To describe the trend in the impact of lower urinary tract symptoms attributed to benign prostatic hyperplasia (LUTS/BPH) on a global scale using the Global Burden of Disease (GBD) database.<h4>Materials and methods</h4>Using the GBD database, worldwide data aggregated from registries and health systems from 1990 to 2017 were filtered for ... Read more >>

BJU Int (BJU international)
[2021, 127(6):722-728]

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Outcomes of combination therapy with daily Tadalafil 5mg plus Tamsulosin 0.4mg to treat lower urinary tract symptoms and erectile dysfunction in men with or without metabolic syndrome.

Arcangelo Sebastianelli, Simone Morselli, Pietro Spatafora, Andrea Liaci, Luca Gemma, Claudia Zaccaro, Linda Vignozzi, Mario Maggi, Kevin T McVary, Steven A Kaplan, Christopher Chapple, Stavros Gravas, Sergio Serni, Mauro Gacci,

<h4>Background</h4>To assess the impact of Tadalafil 5mg/die plus Tamsulosin 0.4mg/die combination therapy on LUTS and ED, according to presence vs. absence of Mets.<h4>Methods</h4>75 consecutive men presenting with ED and LUTS were enrolled. Patients were divided into two groups according to MetS presence. All subjects were treated with combination therapy for ... Read more >>

Minerva Urol Nefrol (Minerva urologica e nefrologica = The Italian journal of urology and nephrology)
[2020, :]

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Mirabegron Vs Placebo Add-on Therapy in Men With Overactive Bladder Symptoms Receiving Tamsulosin for Underlying Benign Prostatic Hyperplasia: A Safety Analysis From the Randomized, Phase 4 PLUS Study.

Sender Herschorn, Kevin T McVary, Javier Cambronero Santos, Steve Foley, Rita M Kristy, Nurul Choudhury, John Hairston, Steven A Kaplan,

<h4>Objective</h4>To analyze the safety of mirabegron add-on therapy in men with overactive bladder symptoms concurrently receiving tamsulosin for lower urinary tract symptoms associated with benign prostatic hyperplasia.<h4>Methods</h4>The Phase 4 PLUS study comprised a 4-week run-in period (tamsulosin [0.4 mg]) and a 12-week randomized treatment period (add-on treatment: mirabegron [25 mg] ... Read more >>

Urology (Urology)
[2021, 147:235-242]

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Larry E Miller, Bilal Chughtai, Ryan A Dornbier, Kevin T McVary,

J Urol (The Journal of urology)
[2020, 204(5):1025-1026]

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The New American Urological Association Benign Prostatic Hyperplasia Clinical Guidelines: 2019 Update.

Ryan Dornbier, Gaurav Pahouja, Jeffrey Branch, Kevin T McVary,

<h4>Purpose of review</h4>The goal of this paper was to analyze the efficacy of the current modalities available to surgically treat lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).<h4>Recent findings</h4>There have been significant surgical advancements for the treatment of BPH, including an increasing development and utilization of minimally ... Read more >>

Curr Urol Rep (Current urology reports)
[2020, 21(9):32]

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Parth M Patel, Sarah E Sweigert, Marc Nelson, Gopal Gupta, Marshall Baker, Frances M Weaver, Kevin T McVary,

J Urol (The Journal of urology)
[2020, 204(2):336]

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Surgical Reintervention Rate after Prostatic Urethral Lift: Systematic Review and Meta-Analysis Involving over 2,000 Patients.

Larry E Miller, Bilal Chughtai, Ryan A Dornbier, Kevin T McVary,

<h4>Purpose</h4>The surgical reintervention rate after prostatic urethral lift is not well characterized but has been estimated at 2% to 3% per year. We performed a systematic review and meta-analysis to determine the surgical reintervention rate after prostatic urethral lift.<h4>Materials and methods</h4>We systematically searched MEDLINE®, Embase® and the Cochrane Central Register ... Read more >>

J Urol (The Journal of urology)
[2020, 204(5):1019-1026]

Cited: 3 times

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A Tower of Babel in Today's Urology: Disagreement in Concepts and Definitions of Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia Re-Treatment.

Kevin T McVary, Steven A Kaplan,

J Urol (The Journal of urology)
[2020, 204(2):213-214]

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Penile Prosthesis Implantation and Timing Disparities After Radical Prostatectomy: Results From a Statewide Claims Database.

Petar Bajic, Parth M Patel, Marc H Nelson, Ryan A Dornbier, Eric J Kirshenbaum, Marshall S Baker, Ahmer V Farooq, Kevin T McVary, Gopal N Gupta, Larissa Bresler,

<h4>Background</h4>Many patients with erectile dysfunction (ED) after radical prostatectomy (RP) improve with conservative therapy but some do not; penile prosthesis implantation rates have been sparsely reported, and have used nonrepresentative data sets.<h4>Aim</h4>To characterize rates and timing of penile prosthesis implantation after RP and to identify predictors of implantation using a ... Read more >>

J Sex Med (The journal of sexual medicine)
[2020, 17(6):1175-1181]

Cited: 2 times

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Steven A Kaplan, Sender Herschorn, Kevin T McVary, David Staskin, Christopher Chapple, Steve Foley, Javier Cambronero Santos, Rita M Kristy, Nurul Choudhury, John Hairston, Carol R Schermer,

J Urol (The Journal of urology)
[2020, 203(6):1171]

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A novel metric for treatment durability in clinical trials of minimally invasive treatments for benign prostatic hyperplasia.

Larry E Miller, Alexis E Te, Samir K Bhattacharyya, Sean Lilienfeld, Ryan A Dornbier, Kevin T McVary,

Introduction: Clinical trial manuscripts commonly report results of individual endpoints. However, durability of a medical treatment may be difficult to determine when evaluating endpoint outcomes individually. We reviewed pivotal trial manuscripts of two minimally invasive benign prostatic hyperplasia (BPH) treatments and estimated the rate of treatment durability using a composite, ... Read more >>

Expert Rev Med Devices (Expert review of medical devices)
[2020, 17(4):365-369]

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Mirabegron improves sleep measures, nocturia, and lower urinary tract symptoms in those with urinary symptoms associated with disordered sleep.

Robert A Petrossian, Danuta Dynda, Kristin Delfino, Ahmed El-Zawahry, Kevin T McVary,

<h4>Introduction</h4>The role of organized sleep in overall health and quality-of-life (QoL) is critical. Nocturia necessarily disrupts the normal sleep cycle and negatively impacts one's health, work productivity, and QoL. We investigated, for the first time in an exploratory pilot, the effectiveness of mirabegron for improving sleep disturbance and nocturia.<h4>Materials and ... Read more >>

Can J Urol (The Canadian journal of urology)
[2020, 27(1):10106-10117]

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Disparities in Benign Prostatic Hyperplasia Progression: Predictors of Presentation to the Emergency Department in Urinary Retention.

Parth M Patel, Sarah E Sweigert, Marc Nelson, Gopal Gupta, Marshall Baker, Frances M Weaver, Kevin T McVary,

PURPOSE:This retrospective cohort study evaluates the characteristics of patients who presented to the emergency department with acute urinary retention. MATERIALS AND METHODS:Using the Healthcare Cost and Utilization Project State Emergency Department Databases we conducted a retrospective cohort study of patients who presented to emergency departments in Florida between 2005 and ... Read more >>

J Urol (The Journal of urology)
[2020, 204(2):332-336]

Cited: 2 times

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Efficacy and Safety of Mirabegron versus Placebo Add-On Therapy in Men with Overactive Bladder Symptoms Receiving Tamsulosin for Underlying Benign Prostatic Hyperplasia: A Randomized, Phase 4 Study (PLUS).

Steven A Kaplan, Sender Herschorn, Kevin T McVary, David Staskin, Christopher Chapple, Steve Foley, Javier Cambronero Santos, Rita M Kristy, Nurul Choudhury, John Hairston, Carol R Schermer,

PURPOSE:PLUS investigated the efficacy and safety of mirabegron add-on therapy in men with overactive bladder symptoms receiving tamsulosin for underlying lower urinary tract symptoms attributable to benign prostatic hyperplasia. MATERIALS AND METHODS:In this phase 4 study a 4-week 0.4 mg tamsulosin run-in period was followed by a 12-week, randomized, double-blind, ... Read more >>

J Urol (The Journal of urology)
[2020, 203(6):1163-1171]

Cited: 3 times

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Water vapor thermal therapy to alleviate catheter-dependent urinary retention secondary to benign prostatic hyperplasia.

Kevin T McVary, Bradley Holland, J Randolf Beahrs,

<h4>Background</h4>Water vapor thermal therapy utilizes convectively delivered thermal energy to target ablation of obstructive prostatic tissue. We report results of this thermal therapy for relief of nonneurogenic complete urinary retention associated with BPH.<h4>Patients and methods</h4>We conducted a retrospective analysis of 38 catheter-dependent men with complete urinary retention consecutively enrolled in ... Read more >>

Prostate Cancer Prostatic Dis (Prostate cancer and prostatic diseases)
[2020, 23(2):303-308]

Cited: 1 time

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Charles Welliver, Lydia Feinstein, Julia B Ward, Chyng-Wen Fwu, Ziya Kirkali, Tamara Bavendam, Brian R Matlaga, Kevin T McVary, ,

J Urol (The Journal of urology)
[2020, 203(1):178]

Cited: 0 times

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Use of Surgery for Post-Prostatectomy Incontinence.

Marc Nelson, Ryan Dornbier, Eric Kirshenbaum, Emanuel Eguia, Patrick Sweigert, Marshall Baker, Ahmer Farooq, Kevin T McVary, Chris M Gonzalez, Gopal Gupta, Larissa Bresler,

PURPOSE:Stress urinary incontinence following radical prostatectomy is common and potentially debilitating. Surgical therapy with a urethral sling or an artificial urinary sphincter is an effective option with high patient satisfaction in men in whom conservative measures fail to treat post-prostatectomy incontinence. We sought to characterize the contemporary utilization of surgical ... Read more >>

J Urol (The Journal of urology)
[2020, 203(4):786-791]

Cited: 2 times

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Which Drug to Discontinue 3 Months After Combination Therapy of Tadalafil plus Tamsulosin for Men with Lower Urinary Tract Symptom and Erectile Dysfunction? Results of a Prospective Observational Trial.

Arcangelo Sebastianelli, Pietro Spatafora, Jacopo Frizzi, Omar Saleh, Cosimo De Nunzio, Andrea Tubaro, Linda Vignozzi, Mario Maggi, Sergio Serni, Kevin T McVary, Steven A Kaplan, Stavros Gravas, Christopher Chapple, Mauro Gacci,

<h4>Background</h4>Safety and efficacy of tamsulosin and tadalafil for men with benign prostatic enlargement (BPE) and/or erectile dysfunction (ED) are defined. However, there are only a few pilot studies on combination therapy with these drugs for men with lower urinary tract symptom (LUTS)/BPE and ED. Moreover, preliminary reports are limited to ... Read more >>

Eur Urol Focus (European urology focus)
[2021, 7(2):432-439]

Cited: 2 times

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Infectious Adverse Events Following the Placement of a Penile Prosthesis: A Systematic Review.

Joseph Mahon, Ryan Dornbier, Grace Wegrzyn, Martha M Faraday, Hossein Sadeghi-Nejad, Lawrence Hakim, Kevin T McVary,

<h4>Introduction</h4>Infection remains a prominent concern following penile implantation. Recognition of the risk factors for infection may help to guide surgeons toward reducing the risk of prosthetic contamination.<h4>Aim</h4>To gain a further understanding of infectious adverse events following penile prosthesis, we performed a systematic literature review.<h4>Methods</h4>As part of the 2018 American Urological ... Read more >>

Sex Med Rev (Sexual medicine reviews)
[2020, 8(2):348-354]

Cited: 3 times

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Trends in Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia, 2004 to 2013: the Urologic Diseases in America Project.

Charles Welliver, Lydia Feinstein, Julia B Ward, Chyng-Wen Fwu, Ziya Kirkali, Tamara Bavendam, Brian R Matlaga, Kevin T McVary, ,

<h4>Purpose</h4>Our current understanding of recent trends in the management of lower urinary tract symptoms associated with benign prostatic hyperplasia is incomplete, particularly in younger men. The 2018 Urologic Diseases in America Project attempted to fill this gap by analyzing multiple large administrative claims databases which include men of all ages ... Read more >>

J Urol (The Journal of urology)
[2020, 203(1):171-178]

Cited: 4 times

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