Full Text Journal Articles by
Author Kevin Oeffinger

Advertisement

Find full text journal articles






Endocrine and Metabolic Disorders in Survivors of Childhood Cancers and Health-Related Quality of Life and Physical Activity.

Kamnesh R Pradhan, Yan Chen, Sogol Moustoufi-Moab, Kevin Krull, Kevin C Oeffinger, Charles Sklar, Gregory T Armstrong, Kirsten K Ness, Leslie Robison, Yutaka Yasui, Paul C Nathan,

CONTEXT:Childhood cancer survivors experience chronic health conditions that impact health-related quality of life (HRQOL) and participation in optimal physical activity. OBJECTIVE:The study aimed to determine independent effects of endocrine and metabolic disorders on HRQOL and physical activity. DESIGN, SETTING, AND PATIENTS:Retrospective cohort with longitudinal follow-up of survivors of childhood cancer ... Read more >>

J. Clin. Endocrinol. Metab. (The Journal of clinical endocrinology and metabolism)
[2019, 104(11):5183-5194]

Cited: 1 time

View full text PDF listing >>



Impact of enucleation on adult retinoblastoma survivors' quality of life: A qualitative study of survivors' perspectives.

Smita C Banerjee, Elaine Pottenger, Mary Petriccione, Joanne F Chou, Jennifer S Ford, Charles A Sklar, Leslie L Robison, Ruth A Kleinerman, Kevin C Oeffinger, Jasmine H Francis, David H Abramson, Ira J Dunkel, Danielle Novetsky Friedman,

OBJECTIVES:Retinoblastoma is the most common primary intraocular tumor of childhood with >95% survival rates in the US. Traditional therapy for retinoblastoma often included enucleation (removal of the eye). While much is known about the visual, physical, and cognitive ramifications of enucleation, data are lacking about survivors' perception of how this ... Read more >>

Palliat Support Care (Palliative & supportive care)
[2019, :1-10]

Cited: 0 times

View full text PDF listing >>



Advertisement

Association of Breast Cancer Risk After Childhood Cancer With Radiation Dose to the Breast and Anthracycline Use: A Report From the Childhood Cancer Survivor Study.

Lene H Veiga, Rochelle E Curtis, Lindsay M Morton, Diana R Withrow, Rebecca M Howell, Susan A Smith, Rita E Weathers, Kevin C Oeffinger, Chaya S Moskowitz, Tara O Henderson, Michael A Arnold, Todd M Gibson, Wendy M Leisenring, Joseph P Neglia, Lucie M Turcotte, John A Whitton, Leslie L Robison, Gregory T Armstrong, Peter D Inskip, Amy Berrington de Gonzalez,

Importance:Chest irradiation for childhood cancer is associated with increases in breast cancer risk. Growing evidence suggests that anthracyclines increase this risk, but the outcome of combined anthracycline use and radiotherapy has not been studied. Objectives:To evaluate breast cancer risk in childhood cancer survivors following radiotherapy and chemotherapy and assess whether ... Read more >>

JAMA Pediatr (JAMA pediatrics)
[2019, :]

Cited: 0 times

View full text PDF listing >>



Cost-Effectiveness of Colonoscopy-Based Colorectal Cancer Screening in Childhood Cancer Survivors.

Andrea Gini, Reinier G S Meester, Homa Keshavarz, Kevin C Oeffinger, Sameera Ahmed, David C Hodgson, Iris Lansdorp-Vogelaar,

BACKGROUND:Childhood cancer survivors (CCS) are at increased risk of developing colorectal cancer (CRC) compared to the general population, especially those previously exposed to abdominal or pelvic radiation therapy (APRT). However, the benefits and costs of CRC screening in CCS are unclear. In this study, we evaluated the cost-effectiveness of early-initiated ... Read more >>

J. Natl. Cancer Inst. (Journal of the National Cancer Institute)
[2019, 111(11):1161-1169]

Cited: 0 times

View full text PDF listing >>



Barriers and facilitators of risk-based health care for adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.

Jennifer S Ford, Emily S Tonorezos, Ann C Mertens, Melissa M Hudson, Jacqueline Casillas, Barbara M Foster, Chaya S Moskowitz, Stephanie M Smith, Joanne F Chou, George Buchanan, Leslie L Robison, Kevin C Oeffinger,

BACKGROUND:Optimal risk-based survivor health care includes surveillance for late effects and education targeted at reducing or preventing risky health behaviors. Understanding the reasons for a lack of risk-based follow-up care is essential. METHODS:Adult participants from the Childhood Cancer Survivor Study were surveyed about having a cancer-related visit in the past ... Read more >>

Cancer (Cancer)
[2019, :]

Cited: 0 times

View full text PDF listing >>



Solid organ transplantation after treatment for childhood cancer: a retrospective cohort analysis from the Childhood Cancer Survivor Study.

Andrew C Dietz, Kristy Seidel, Wendy M Leisenring, Daniel A Mulrooney, Jean M Tersak, Richard D Glick, Cathy A Burnweit, Daniel M Green, Lisa R Diller, Susan A Smith, Rebecca M Howell, Marilyn Stovall, Gregory T Armstrong, Kevin C Oeffinger, Leslie L Robison, Amanda M Termuhlen,

BACKGROUND:Serious chronic medical conditions occur in childhood cancer survivors. We aimed to investigate incidence of and risk factors for end-organ damage resulting in registration on a waiting list for or receiving a solid organ transplantation and 5-year survival following these procedures. METHODS:The Childhood Cancer Survivor Study (CCSS) is a retrospective ... Read more >>

Lancet Oncol. (The Lancet. Oncology)
[2019, 20(10):1420-1431]

Cited: 0 times

View full text PDF listing >>



Childhood Leukemia, Late Effects, and a Person-centric Model of Follow-up.

Miranda M Fidler-Benaoudia, Kevin C Oeffinger,

J. Natl. Cancer Inst. (Journal of the National Cancer Institute)
[2019, 111(9):880-881]

Cited: 0 times

View full text PDF listing >>



Mortality After Breast Cancer Among Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study.

Chaya S Moskowitz, Joanne F Chou, Joseph P Neglia, Ann H Partridge, Rebecca M Howell, Lisa R Diller, Danielle Novetsky Friedman, Dana Barnea, Lindsay M Morton, Lucie M Turcotte, Michael A Arnold, Wendy M Leisenring, Gregory T Armstrong, Leslie L Robison, Kevin C Oeffinger, Tara O Henderson,

PURPOSE:Female survivors of childhood cancer have a high risk of subsequent breast cancer. We describe the ensuing risk for mortality and additional breast cancers. PATIENTS AND METHODS:Female participants in the Childhood Cancer Survivor Study, a cohort of 5-year survivors of cancer diagnosed between 1970 and 1986 before age 21 years, ... Read more >>

J. Clin. Oncol. (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2019, 37(24):2120-2130]

Cited: 0 times

View full text PDF listing >>



Radiation Dose and Volume to the Pancreas and Subsequent Risk of Diabetes Mellitus.

Danielle Novetsky Friedman, Chaya S Moskowitz, Patrick Hilden, Rebecca M Howell, Rita E Weathers, Susan A Smith, Suzanne L Wolden, Emily S Tonorezos, Sogol Mostoufi-Moab, Eric J Chow, Lillian R Meacham, Joanne F Chou, John A Whitton, Wendy M Leisenring, Leslie L Robison, Gregory T Armstrong, Kevin C Oeffinger, Charles A Sklar,

BACKGROUND:Childhood cancer survivors exposed to abdominal radiation (abdRT) are at increased risk for diabetes mellitus but the association between risk and radiation dose and volume is unclear. METHODS:Participants included 20,762 five-year survivors of childhood cancer (4,568 exposed to abdRT) and 4,853 siblings. For abdRT, we estimated maximum dose to abdomen, ... Read more >>

J. Natl. Cancer Inst. (Journal of the National Cancer Institute)
[2019, :]

Cited: 0 times

View full text PDF listing >>



Promoting Breast Cancer Surveillance: The EMPOWER Study, a Randomized Clinical Trial in the Childhood Cancer Survivor Study.

Kevin C Oeffinger, Jennifer S Ford, Chaya S Moskowitz, Joanne F Chou, Tara O Henderson, Melissa M Hudson, Lisa Diller, Aaron McDonald, James Ford, Nidha Z Mubdi, Dayton Rinehart, Christopher Vukadinovich, Todd M Gibson, Nassim Anderson, Elena B Elkin, Kathleen Garrett, Margaret Rebull, Wendy Leisenring, Leslie L Robison, Gregory T Armstrong,

PURPOSE:The aim of the current study was to increase the uptake of screening mammography among high-risk women who were treated for a childhood cancer with chest radiotherapy. PATIENTS AND METHODS:Two hundred four female survivors in the Childhood Cancer Survivor Study who were treated with chest radiotherapy with 20 Gy or ... Read more >>

J. Clin. Oncol. (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2019, 37(24):2131-2140]

Cited: 0 times

View full text PDF listing >>



Late-onset anorectal disease and psychosocial impact in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.

Arin L Madenci, Bryan V Dieffenbach, Qi Liu, Daisuke Yoneoka, Jamie Knell, Todd M Gibson, Yutaka Yasui, Wendy M Leisenring, Rebecca M Howell, Lisa R Diller, Kevin R Krull, Gregory T Armstrong, Kevin C Oeffinger, Andrew J Murphy, Brent R Weil, Christopher B Weldon,

BACKGROUND:The prevalence and associated psychosocial morbidity of late-onset anorectal disease after surgery and radiotherapy for the treatment of childhood cancer are not known. METHODS:A total of 25,530 survivors diagnosed between 1970 and 1999 (median age at cancer diagnosis, 6.1 years; age at survey, 30.2 years) and 5036 siblings were evaluated for late-onset ... Read more >>

Cancer (Cancer)
[2019, 125(21):3873-3881]

Cited: 0 times

View full text PDF listing >>



Automated Breast Density Measurements From Chest Computed Tomography Scans.

Touseef A Qureshi, Harini Veeraraghavan, Janice S Sung, Jennifer B Kaplan, Jessica Flynn, Emily S Tonorezos, Suzanne L Wolden, Elizabeth A Morris, Kevin C Oeffinger, Malcolm C Pike, Chaya S Moskowitz,

To develop an automated method for quantifying percent breast density from chest computed tomography (CT) scans. A naïve Bayesian classifier based on gray-level intensities and spatial relationships was developed on CT scans from 10 patients diagnosed with Hodgkin lymphoma (HL) and imaged as part of routine clinical care. The algorithm ... Read more >>

J Med Syst (Journal of medical systems)
[2019, 43(8):242]

Cited: 0 times

View full text PDF listing >>



Late Health Outcomes After Contemporary Lymphome Malin de Burkitt Therapy for Mature B-Cell Non-Hodgkin Lymphoma: A Report From the Childhood Cancer Survivor Study.

Matthew J Ehrhardt, Yan Chen, John T Sandlund, Elizabeth C Bluhm, Robert J Hayashi, Kerri Becktell, Wendy M Leisenring, Monika L Metzger, Kirsten K Ness, Kevin R Krull, Kevin C Oeffinger, Todd M Gibson, Mitchell S Cairo, Thomas G Gross, Leslie L Robison, Gregory T Armstrong, Yutaka Yasui, Melissa M Hudson, Daniel A Mulrooney,

PURPOSE:The widely used, risk-based Lymphome Malin de Burkitt (LMB) chemotherapy regimen has improved survival rates for children with mature B-cell non-Hodgkin lymphoma (NHL); however, associated late effects remain understudied. We assessed late health outcomes after LMB treatment in the Childhood Cancer Survivor Study. PATIENTS AND METHODS:Multivariable regression models compared chronic ... Read more >>

J. Clin. Oncol. (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2019, 37(28):2556-2570]

Cited: 0 times

View full text PDF listing >>



Traditional cardiovascular risk factors and individual prediction of cardiovascular events in childhood cancer survivors.

Yan Chen, Eric J Chow, Kevin C Oeffinger, William L Border, Wendy M Leisenring, Lillian R Meacham, Daniel A Mulrooney, Charles A Sklar, Marilyn Stovall, Leslie L Robison, Gregory T Armstrong, Yutaka Yasui,

BACKGROUND:Childhood cancer survivors have an increased risk of heart failure, ischemic heart disease, and stroke. They may benefit from prediction models that account for cardiotoxic cancer treatment exposures combined with information on traditional cardiovascular risk factors such as hypertension, dyslipidemia, and diabetes. METHODS:Childhood Cancer Survivor Study participants (n = 22,643) were followed ... Read more >>

J. Natl. Cancer Inst. (Journal of the National Cancer Institute)
[2019, :]

Cited: 0 times

View full text PDF listing >>



Derivation of Anthracycline and Anthraquinone Equivalence Ratios to Doxorubicin for Late-Onset Cardiotoxicity.

Elizabeth A M Feijen, Wendy M Leisenring, Kayla L Stratton, Kirsten K Ness, Helena J H van der Pal, Elvira C van Dalen, Gregory T Armstrong, Gregory J Aune, Daniel M Green, Melissa M Hudson, Jacqueline Loonen, Kevin C Oeffinger, Leslie L Robison, Yutaka Yasui, Leontien C M Kremer, Eric J Chow,

Importance:Anthracyclines are part of many effective pediatric cancer treatment protocols. Most pediatric oncology treatment groups assume that the hematologic toxicity of anthracycline agents is equivalent to their cardiotoxicity; for example, Children's Oncology Group substitution rules consider daunorubicin and epirubicin isoequivalent to doxorubicin, whereas mitoxantrone and idarubicin are considered 4 to ... Read more >>

JAMA Oncol (JAMA oncology)
[2019, 5(6):864-871]

Cited: 0 times

View full text PDF listing >>



Impact of exercise on psychological burden in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.

Emily S Tonorezos, Jennifer S Ford, Linwei Wang, Kirsten K Ness, Yutaka Yasui, Wendy Leisenring, Charles A Sklar, Leslie L Robison, Kevin C Oeffinger, Paul C Nathan, Gregory T Armstrong, Kevin Krull, Lee W Jones,

BACKGROUND:Childhood cancer survivors are at risk for adverse psychological outcomes. Whether exercise can attenuate this risk is unknown. METHODS:In total, 6199 participants in the Childhood Cancer Survivor Study (median age, 34.3 years [range, 22.0-54.0 years]; median age at diagnosis, 10.0 years [range, 0-21.0 years]) completed a questionnaire assessing vigorous exercise and medical/psychological conditions. Outcomes ... Read more >>

Cancer (Cancer)
[2019, 125(17):3059-3067]

Cited: 0 times

View full text PDF listing >>



Oncologists' Attitudes and Practice of Addressing Diet, Physical Activity, and Weight Management With Patients With Cancer: Findings of an ASCO Survey of the Oncology Workforce.

Jennifer A Ligibel, Lee W Jones, Abenaa M Brewster, Steven K Clinton, Larissa A Korde, Kevin C Oeffinger, Catherine M Bender, Winston Tan, Janette K Merrill, Sweatha Katta, Catherine M Alfano,

PURPOSE:Obesity and related factors have been linked to cancer risk and outcomes, but little information exists with regard to oncologists' attention to these issues as a part of clinical care. METHODS:Oncology providers actively caring for patients with cancer in the United States and internationally were asked to complete an online ... Read more >>

J Oncol Pract (Journal of oncology practice)
[2019, 15(6):e520-e528]

Cited: 0 times

View full text PDF listing >>



Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors: A Scientific Statement From the American Heart Association.

Susan C Gilchrist, Ana Barac, Philip A Ades, Catherine M Alfano, Barry A Franklin, Lee W Jones, Andre La Gerche, Jennifer A Ligibel, Gabriel Lopez, Kushal Madan, Kevin C Oeffinger, Jeannine Salamone, Jessica M Scott, Ray W Squires, Randal J Thomas, Diane J Treat-Jacobson, Janet S Wright, ,

Cardiovascular disease is a competing cause of death in patients with cancer with early-stage disease. This elevated cardiovascular disease risk is thought to derive from both the direct effects of cancer therapies and the accumulation of risk factors such as hypertension, weight gain, cigarette smoking, and loss of cardiorespiratory fitness. ... Read more >>

Circulation (Circulation)
[2019, 139(21):e997-e1012]

Cited: 0 times

View full text PDF listing >>



Therapy-Related Cardiac Risk in Childhood Cancer Survivors: An Analysis of the Childhood Cancer Survivor Study.

James E Bates, Rebecca M Howell, Qi Liu, Yutaka Yasui, Daniel A Mulrooney, Sughosh Dhakal, Susan A Smith, Wendy M Leisenring, Daniel J Indelicato, Todd M Gibson, Gregory T Armstrong, Kevin C Oeffinger, Louis S Constine,

PURPOSE:The impacts of radiotherapy dose and exposed cardiac volume, select chemotherapeutic agents, and age at exposure on risk for late-onset cardiac disease in survivors of childhood cancer remain unresolved. PATIENTS AND METHODS:We determined the rates of severe to fatal cardiac disease in 24,214 5-year survivors in the Childhood Cancer Survivor ... Read more >>

J. Clin. Oncol. (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2019, 37(13):1090-1101]

Cited: 0 times

View full text PDF listing >>



Assessment of Early Radiation-Induced Changes in Left Ventricular Function by Myocardial Strain Imaging After Breast Radiation Therapy.

Anthony F Yu, Alice Y Ho, Lior Z Braunstein, Maria E Thor, Katherine Lee Chuy, Anne Eaton, Elton Mara, Oren Cahlon, Chau T Dang, Kevin C Oeffinger, Richard M Steingart, Jennifer E Liu,

BACKGROUND:Radiation therapy (RT)-induced cardiotoxicity is among the concerning sequelae of breast cancer (BCA) treatment, particularly in HER2-positive BCA patients who receive anthracyclines and trastuzumab-based therapy. The aim of this study was to assess for early RT-induced changes in echocardiographic and circulating biomarkers of left ventricular (LV) function and evaluate their ... Read more >>

J Am Soc Echocardiogr (Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography)
[2019, 32(4):521-528]

Cited: 0 times

View full text PDF listing >>



Sleep, emotional distress, and physical health in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.

Lauren C Daniel, Mingjuan Wang, Daniel A Mulrooney, Deo Kumar Srivastava, Lisa A Schwartz, Kim Edelstein, Tara M Brinkman, Eric S Zhou, Rebecca M Howell, Todd M Gibson, Wendy Leisenring, Kevin C Oeffinger, Joseph Neglia, Leslie L Robison, Gregory T Armstrong, Kevin R Krull,

OBJECTIVE:Sleep disorders are associated with psychological and physical health, although reports in long-term survivors of childhood cancer are limited. We characterized the prevalence and risk factors for behaviors consistent with sleep disorders in survivors and examined longitudinal associations with emotional distress and physical health outcomes. METHODS:Survivors (n = 1933; median [IQR] age = 35 ... Read more >>

Psychooncology (Psycho-oncology)
[2019, 28(4):903-912]

Cited: 0 times

View full text PDF listing >>



Late Morbidity and Mortality Among Medulloblastoma Survivors Diagnosed Across Three Decades: A Report From the Childhood Cancer Survivor Study.

Ralph Salloum, Yan Chen, Yutaka Yasui, Roger Packer, Wendy Leisenring, Elizabeth Wells, Allison King, Rebecca Howell, Todd M Gibson, Kevin R Krull, Leslie L Robison, Kevin C Oeffinger, Maryam Fouladi, Gregory T Armstrong,

PURPOSE:Treatment of medulloblastoma has evolved from surgery and radiotherapy to contemporary multimodal regimens. However, the impact on long-term health outcomes remains unknown. METHODS:Cumulative incidence of late mortality (5 or more years from diagnosis), subsequent neoplasms (SNs), and chronic health conditions were evaluated in the Childhood Cancer Survivor Study among 5-year ... Read more >>

J. Clin. Oncol. (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2019, 37(9):731-740]

Cited: 0 times

View full text PDF listing >>



Advanced Practice Providers and Survivorship Care: They Can Deliver.

Bridgette Thom, Annelies H Boekhout, Stacie Corcoran, Roberto Adsuar, Kevin C Oeffinger, Mary S McCabe,

INTRODUCTION::As the number of cancer survivors grows, new models of survivorship care are being implemented, but there is limited evaluation to date. This retrospective review assesses the concordance of care provided to adult-onset cancer survivors by advanced practice providers (nurse practitioners and physician assistants) with Institute of Medicine guidelines for ... Read more >>

J Oncol Pract (Journal of oncology practice)
[2019, 15(3):e230-e237]

Cited: 0 times

View full text PDF listing >>



Care coordination for complex cancer survivors in an integrated safety-net system: a study protocol.

Simon J Craddock Lee, Katelyn K Jetelina, Emily Marks, Eric Shaw, Kevin Oeffinger, Deborah Cohen, Noel O Santini, John V Cox, Bijal A Balasubramanian,

BACKGROUND:The growing numbers of cancer survivors challenge delivery of high-quality survivorship care by healthcare systems. Innovative ways to improve care coordination for patients with cancer and multiple chronic conditions ("complex cancer survivors") are needed to achieve better care outcomes, improve patient experience of care, and lower cost. Our study, Project ... Read more >>

BMC Cancer (BMC cancer)
[2018, 18(1):1204]

Cited: 1 time

View full text PDF listing >>



Long-term health and social function in adult survivors of paediatric astrocytoma: A report from the Childhood Cancer Survivor Study.

Karen E Effinger, Kayla L Stratton, Paul Graham Fisher, Kirsten K Ness, Kevin R Krull, Kevin C Oeffinger, Gregory T Armstrong, Leslie L Robison, Melissa M Hudson, Wendy M Leisenring, Paul C Nathan,

BACKGROUND:Although paediatric astrocytoma has an excellent 5-year survival rate, survivors remain at risk for morbidity and late mortality. This study aimed to estimate the risk of late mortality, chronic conditions, poor health status and social impairment in ageing paediatric astrocytoma survivors. METHODS:We longitudinally evaluated 1182 5-year astrocytoma survivors diagnosed between ... Read more >>

Eur. J. Cancer (European journal of cancer (Oxford, England : 1990))
[2019, 106:171-180]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.4778 s