Full Text Journal Articles by
Author Kevin Jones

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Association of outcomes in acute flaccid myelitis with identification of enterovirus at presentation: a Canadian, nationwide, longitudinal study.

Carmen Yea, Ari Bitnun, Helen M Branson, Beyza Ciftci-Kavaklioglu, Mubeen F Rafay, Olivier Fortin, Paola Moresoli, Guillaume Sébire, Myriam Srour, Hélène Decaluwe, Louis Marois, Félixe Pelletier, Michelle Barton, Maryam Nabavi Nouri, Jason Brophy, Sunita Venkateswaran, Daniela Pohl, Kathryn Selby, Kevin Jones, Joan Robinson, Aleksandra Mineyko, Christoph Licht, Birgit Ertl-Wagner, E Ann Yeh,

BACKGROUND:Acute flaccid myelitis (AFM) is characterised by rapid onset of limb weakness with spinal cord grey-matter abnormalities on MRI scan. We aimed to assess whether detection of enterovirus in respiratory or other specimens can help predict prognosis in children with AFM. METHODS:In this nationwide, longitudinal study, we evaluated the significance ... Read more >>

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2020, 4(11):828-836]

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In Situ Catchment Scale Sampling of Emerging Contaminants Using Diffusive Gradients in Thin Films (DGT) and Traditional Grab Sampling: A Case Study of the River Thames, UK.

Runmei Wang, Emma Biles, Yanying Li, Monika D Juergens, Michael J Bowes, Kevin C Jones, Hao Zhang,

The in situ passive sampling technique, diffusive gradients in thin films (DGT), confronts many of the challenges associated with current sampling methods used for emerging contaminants (ECs) in aquatic systems. This study compared DGT and grab sampling for their suitability to screen and monitor ECs at the catchment scale in ... Read more >>

Environ Sci Technol (Environmental science & technology)
[2020, 54(18):11155-11164]

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The epigenomics of sarcoma.

Benjamin A Nacev, Kevin B Jones, Andrew M Intlekofer, Jamie S E Yu, C David Allis, William D Tap, Marc Ladanyi, Torsten O Nielsen,

Epigenetic regulation is critical to physiological control of development, cell fate, cell proliferation, genomic integrity and, fundamentally, transcriptional regulation. This epigenetic control occurs at multiple levels including through DNA methylation, histone modification, nucleosome remodelling and modulation of the 3D chromatin structure. Alterations in genes that encode chromatin regulators are common ... Read more >>

Nat Rev Cancer (Nature reviews. Cancer)
[2020, 20(10):608-623]

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Scatter imaging during lung stereotactic body radiation therapy characterized with phantom studies.

Kevin C Jones, Julius Turian, Gage Redler, Gizem Cifter, John Strologas, Alistair Templeton, Damian Bernard, James C H Chu,

By collecting photons scattered out of the therapy beam, scatter imaging creates images of the treated volume. Two phantoms were used to assess the possible application of scatter imaging for markerless tracking of lung tumors during stereotactic body radiation therapy (SBRT) treatment. A scatter-imaging camera was assembled with a CsI ... Read more >>

Phys Med Biol (Physics in medicine and biology)
[2020, 65(15):155013]

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Boarding of Critically Ill Patients in the Emergency Department.

Nicholas M Mohr, Brian T Wessman, Benjamin Bassin, Marie-Carmelle Elie-Turenne, Timothy Ellender, Lillian L Emlet, Zachary Ginsberg, Kyle Gunnerson, Kevin M Jones, Bridgette Kram, Evie Marcolini, Susanna Rudy,

OBJECTIVES:Emergency department boarding is the practice of caring for admitted patients in the emergency department after hospital admission, and boarding has been a growing problem in the United States. Boarding of the critically ill has achieved specific attention because of its association with poor clinical outcomes. Accordingly, the Society of ... Read more >>

Crit. Care Med. (Critical care medicine)
[2020, 48(8):1180-1187]

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Boarding of critically Ill patients in the emergency department.

Nicholas M Mohr, Brian T Wessman, Benjamin Bassin, Marie-Carmelle Elie-Turenne, Timothy Ellender, Lillian L Emlet, Zachary Ginsberg, Kyle Gunnerson, Kevin M Jones, Bridgette Kram, Evie Marcolini, Susanna Rudy,

Objectives:Emergency department boarding is the practice of caring for admitted patients in the emergency department after hospital admission, and boarding has been a growing problem in the United States. Boarding of the critically ill has achieved specific attention because of its association with poor clinical outcomes. Accordingly, the Society of ... Read more >>

J Am Coll Emerg Physicians Open (Journal of the American College of Emergency Physicians open)
[2020, 1(4):423-431]

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Boarding of critically Ill patients in the emergency department

Nicholas M. Mohr, Brian T. Wessman, Benjamin Bassin, Marie‐Carmelle Elie‐Turenne, Timothy Ellender, Lillian L. Emlet, Zachary Ginsberg, Kyle Gunnerson, Kevin M. Jones, Bridgette Kram, Evie Marcolini, Susanna Rudy,

Abstract Objectives Emergency department boarding is the practice of caring for admitted patients in the emergency department after hospital admission, and boarding has been a growing problem in the United States. Boarding of the critically ill has achieved specific attention because of its association with poor clinical outcomes. Accordingly, the ... Read more >>

J Am Coll Emerg Physicians Open (Journal of the American College of Emergency Physicians open)
[2020, 1(4):423-431]

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Genetic variants associated with rotator cuff tearing utilizing multiple population-based genetic resources.

Robert Z Tashjian, Stuart K Kim, Megan D Roche, Kevin B Jones, Craig C Teerlink,

BACKGROUND:The etiology of rotator cuff tearing is likely multifactorial, including a potential genetic predisposition. The purpose of the study was to identify genetic variants associated with rotator cuff tearing utilizing the UK Biobank (UKB) cohort, confirm variants using a separate genetic database, and evaluate tissue expression of genes with associated ... Read more >>

J Shoulder Elbow Surg (Journal of shoulder and elbow surgery)
[2020, :]

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A year-long passive sampling of phenolic endocrine disrupting chemicals in the East River, South China.

Chang-Er Chen, You-Sheng Liu, Ricky Dunn, Jian-Liang Zhao, Kevin C Jones, Hao Zhang, Guang-Guo Ying, Andrew J Sweetman,

The occurrence of endocrine disrupting chemicals (EDCs) in the aquatic environment is a global concern. In this study, we employed two different passive samplers Diffusive Gradients in Thin-films (DGT) and Chemcatcher for in situ measurement of 8 phenolic EDCs in the East River of the Pearl River system over one-year. ... Read more >>

Environ Int (Environment international)
[2020, 143:105936]

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Gene Expression in Torn Rotator Cuff Tendons Determined by RNA Sequencing.

Robert Z Tashjian, Ian Lock, Erin K Granger, Yangliang Wang, Younghee Lee, Peter N Chalmers, Kevin B Jones,

Background:Although the cause of rotator cuff tearing is likely multifactorial and a genetic predisposition has been proposed, the biochemical basis remains unknown. Purpose:To determine gene expression profiles in torn rotator cuff tendon tissue through use of RNA sequencing. Study Design:Controlled laboratory study. Methods:The supraspinatus tendon edge was biopsied in 24 ... Read more >>

Orthop J Sports Med (Orthopaedic journal of sports medicine)
[2020, 8(6):2325967120927480]

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Sequence and characterization of shuttle vectors for molecular cloning in Porphyromonas, Bacteroides and related bacteria.

Kevin R Jones, Benjamin Ross Belvin, Francis L Macrina, Janina P Lewis,

There is a lack of shuttle vectors to be needed for investigations into the genetics of Porphyromonas gingivalis and related species. To better understand the prevalence of candidates for such tools, we have examined multiple strains of black-pigmented anaerobes (clinical and laboratory isolates) for plasmids. As no plasmids were found ... Read more >>

Mol Oral Microbiol (Molecular oral microbiology)
[2020, 35(4):181-191]

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Wet-chemical etching of FIB lift-out TEM lamellae for damage-free analysis of 3-D nanostructures.

Emily M Turner, Keshab R Sapkota, Christopher Hatem, Ping Lu, George T Wang, Kevin S Jones,

Reducing ion beam damage from the focused ion beam (FIB) during fabrication of cross sections is a well-known challenge for materials characterization, especially cross sectional characterization of nanostructures. To address this, a new method has been developed for cross section fabrication enabling high resolution transmission electron microscopy (TEM) analysis of ... Read more >>

Ultramicroscopy (Ultramicroscopy)
[2020, 216:113049]

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Monitoring Organic Pollutants in Waters Using the Diffusive Gradients in the Thin Films Technique: Investigations on the Effects of Biofouling and Degradation.

Runmei Wang, Kevin C Jones, Hao Zhang,

The diffusive gradients in thin films (DGT) passive sampling technique has been increasingly used to provide time-weighted average concentrations of the biorelevant fraction of organic contaminants in waters, with high spatial and temporal resolutions at low cost. This study was tested for the effects of biofouling and compound degradation/loss during ... Read more >>

Environ Sci Technol (Environmental science & technology)
[2020, 54(13):7961-7969]

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Cardiac Arrest Prior to Initiation of Veno-Venous Extracorporeal Membrane Oxygenation Is Not Associated with Increased In-Hospital Mortality.

Kevin M Jones, Laura DiChiacchio, Kristopher B Deatrick, Katelyn Dolly, Jeffrey Rea, Samuel Galvagno, Daniel Herr, James O'Connor, Thomas Scalea, Jay Menaker,

ASAIO J (ASAIO journal (American Society for Artificial Internal Organs : 1992))
[2020, 66(6):e79-e81]

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SKP2 My Lou, My Darling.

Sydney L Lambert, Kevin B Jones,

Myxofibrosarcoma and undifferentiated pleomorphic sarcoma (UPS) lack specific molecular underpinnings, show high rates of metastasis, and display limited responsiveness to current therapies, making them challenging cancers both to treat and to study. It has been noted that MFS and UPS frequently lose function of the tumor suppressor genes RB1 and ... Read more >>

Cancer Res (Cancer research)
[2020, 80(12):2437-2438]

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Decadal shifts in soil pH and organic matter differ between land uses in contrasting regions in China.

Yiming Sun, Guanlin Guo, Huading Shi, Mengjiao Liu, Aidan Keith, Hong Li, Kevin C Jones,

Soil organic matter (SOM) and pH are critical soil properties strongly linked to carbon storage, nutrient cycling and crop productivity. Land use is known to have a dominant impact on these key soil properties, but we often lack the ability to examine temporal trajectories across extensive spatial scales. Large-scale monitoring ... Read more >>

Sci Total Environ (The Science of the total environment)
[2020, 740:139904]

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Modulation of auditory gamma-band responses using transcranial electrical stimulation.

Kevin T Jones, Elizabeth L Johnson, Zoe S Tauxe, Donald C Rojas,

Auditory gamma-band (>30 Hz) activity is a biomarker of cortical excitation/inhibition (E/I) balance in autism, schizophrenia, and bipolar disorder. We provide a comprehensive account of the effects of transcranial alternating current stimulation (tACS) and transcranial direct current stimulation (tDCS) on gamma responses. Forty-five healthy young adults listened to 40-Hz auditory ... Read more >>

J Neurophysiol (Journal of neurophysiology)
[2020, 123(6):2504-2514]

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National Comprehensive Cancer Network guidelines compliance of a sarcoma service: A retrospective review.

Alan T Blank, Brandon Michael Larson, Sara Shaw, Connor J Wakefield, Tricia King, Kevin B Jones, R Lor Randall,

BACKGROUND:Clinical workup and treatment guidelines have been published by the National Comprehensive Cancer Network (NCCN) to ensure patients are treated uniformly and appropriately. This study sought to retrospectively review patients with a new diagnosis of sarcoma who were treated in a National Cancer Institute (NCI) designated center and determine compliance ... Read more >>

World J Clin Oncol (World journal of clinical oncology)
[2020, 11(6):389-396]

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Signal advance and delay due to an optical phase-sensitive amplifier.

Nicholas R Brewer, Tian Li, Kevin M Jones, Paul D Lett,

Fast and slow light media exploit a steep frequency dependence in their index of refraction in order to advance or delay a modulated signal. Here we observe a qualitatively similar advance and delay from an optical phase-sensitive amplifier (PSA). Unlike in the case of slow and fast light, this effect ... Read more >>

Opt Express (Optics express)
[2020, 28(10):14573-14579]

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Water Browning Controls Adaptation and Associated Trade-Offs in Phytoplankton Stressed by Chemical Pollution.

Simone Rizzuto, Jan-Erik Thrane, Didier L Baho, Kevin C Jones, Hao Zhang, Dag O Hessen, Luca Nizzetto, Eva Leu,

The acquisition of tolerance to an environmental stressor can result in organisms displaying slower growth after stress release. While well-grounded in the theory, empirical evidence of the trade-off between stress tolerance and organism fitness is scarce and blurred by the interaction with different environmental factors. Here, we report the effects ... Read more >>

Environ Sci Technol (Environmental science & technology)
[2020, 54(9):5569-5579]

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Genomics of MPNST (GeM) Consortium: Rationale and Study Design for Multi-Omic Characterization of NF1-Associated and Sporadic MPNSTs.

David T Miller, Isidro Cortés-Ciriano, Nischalan Pillay, Angela C Hirbe, Matija Snuderl, Marilyn M Bui, Katherine Piculell, Alyaa Al-Ibraheemi, Brendan C Dickson, Jesse Hart, Kevin Jones, Justin T Jordan, Raymond H Kim, Daniel Lindsay, Yoshihiro Nishida, Nicole J Ullrich, Xia Wang, Peter J Park, Adrienne M Flanagan,

The Genomics of Malignant Peripheral Nerve Sheath Tumor (GeM) Consortium is an international collaboration focusing on multi-omic analysis of malignant peripheral nerve sheath tumors (MPNSTs), the most aggressive tumor associated with neurofibromatosis type 1 (NF1). Here we present a summary of current knowledge gaps, a description of our consortium and ... Read more >>

Genes (Basel) (Genes)
[2020, 11(4):]

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Underlying Ossification Phenotype in a Murine Model of Metastatic Synovial Sarcoma.

Matthew Kirkham, Austen Kalivas, Kaniz Fatema, Sarah Luelling, Brooke H Dubansky, Benjamin Dubansky, Kevin B Jones, Jared J Barrott,

Synovial sarcoma, an uncommon cancer, typically affects young adults. Survival rates range from 36% to 76%, decreasing significantly when metastases are present. Synovial sarcomas form in soft tissues, often near bones, with about 10% demonstrating ossification in the tumor. The literature is inconclusive on whether the presence of ossification portends ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(7):]

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Interrogating cadmium and lead biosorption mechanisms by Simplicillium chinense via infrared spectroscopy.

Zhongmin Jin, Lin Xie, Tuo Zhang, Lijie Liu, Tom Black, Kevin C Jones, Hao Zhang, Xinzi Wang, Naifu Jin, Dayi Zhang,

Fungi-associated phytoremediation is an environmentally friendly and cost-efficient approach to remove potential toxic elements (PTEs) from contaminated soils. Many fungal strains have been reported to possess PTE-biosorption behaviour which benefits phytoremediation performance. Nevertheless, most studies are limited in rich or defined medium, far away from the real-world scenarios where nutrients ... Read more >>

Environ Pollut (Environmental pollution (Barking, Essex : 1987))
[2020, 263(Pt A):114419]

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What factors influence patient experience in orthopedic oncology office visits?

Alan T Blank, Sara Shaw, Connor J Wakefield, Yue Zhang, Wei J Liu, Kevin B Jones, R Lor Randall,

BACKGROUND:Patient satisfaction and reported outcomes are becoming increasingly important in determining the efficacy of clinical care. To date no study has evaluated the patient experience in the orthopedic oncology outpatient setting to determine which factors of the encounter are priorities to the patient. AIM:To evaluate what factors impact patient experience ... Read more >>

World J Clin Oncol (World journal of clinical oncology)
[2020, 11(3):136-142]

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Soil pollution at a major West African E-waste recycling site: Contamination pathways and implications for potential mitigation strategies.

Claudia Moeckel, Knut Breivik, Therese Haugdahl Nøst, Alhaji Sankoh, Kevin C Jones, Andrew Sweetman,

Organic contaminants (polycyclic aromatic hydrocarbons (PAHs), polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), and chlorinated paraffins (CPs)) and heavy metals and metalloids (Ag, Cd, Co, Cr, Cu, Hg, Ni, Pb, Sb, Zn) were analysed in surface soil samples from the Agbogbloshie e-waste processing and dumping site in Accra (Ghana). In ... Read more >>

Environ Int (Environment international)
[2020, 137:105563]

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