Full Text Journal Articles by
Author Kenneth K Kwok

Advertisement

Find full text journal articles








Worldwide post-marketing safety surveillance experience with tofacitinib in ulcerative colitis.

David T Rubin, Irene Modesto, Séverine Vermeire, Silvio Danese, Siew C Ng, Kenneth K Kwok, Nana Koram, Thomas V Jones,

<h4>Background</h4>Tofacitinib is an oral Janus kinase inhibitor for the treatment of ulcerative colitis (UC). Post-marketing surveillance (PMS) is an important part of monitoring adverse events (AEs).<h4>Aims</h4>To report an analysis of PMS case safety reports for tofacitinib in patients with UC METHODS: Worldwide tofacitinib PMS reports received in the Pfizer safety ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, :]

Cited: 0 times

View full text PDF listing >>



A retrospective, pooled data analysis of the safety of pegaptanib sodium in the treatment of age-related macular degeneration in subjects with or without diabetes mellitus.

Theresa Dombi, Kenneth K Kwok, Marla B Sultan,

<h4>Background</h4>To evaluate the safety of pegaptanib sodium 0.3 mg intravitreal injection in the treatment of neovascular age-related macular degeneration in subjects with or without diabetes mellitus.<h4>Methods</h4>A pooled, retrospective, analysis was conducted of data from 9 sponsor-administered, randomized, open-label trials. Subjects who received pegaptanib by randomization or change in dose assignment, ... Read more >>

BMC Ophthalmol (BMC ophthalmology)
[2012, 12:37]

Cited: 7 times

View full text PDF listing >>



Advertisement

Five-year, multicenter safety study of fixed-combination latanoprost/timolol (Xalacom) for open-angle glaucoma and ocular hypertension.

Albert Alm, John W Grunden, Kenneth K Kwok,

<h4>Purpose</h4>To evaluate the safety of fixed-combination latanoprost/timolol (Xalacom) in patients requiring additional intraocular pressure (IOP) reduction over 5 years.<h4>Methods</h4>This phase 3b, open-label, multicenter study included prostaglandin-naive participants with open-angle glaucoma or ocular hypertension insufficiently responsive to β-blockers and requiring additional IOP reduction. Participants were evaluated at eleven 6-month visits. A ... Read more >>

J Glaucoma (Journal of glaucoma)
[2011, 20(4):215-222]

Cited: 7 times

View full text PDF listing >>



Lack of evidence for a link between latanoprost use and malignant melanoma: an analysis of safety databases and a review of the literature.

Charles S Tressler, Robert L Wiseman, Theresa M Dombi, Bart Jessen, Kui Huang, Kenneth K Kwok, Barbara M Wirostko,

<h4>Aim</h4>To determine if there is an association between the use of latanoprost ophthalmic solution and malignant melanoma and to assess the evidence of a plausible biological mechanism.<h4>Methods</h4>Two safety databases were reviewed: one representing all latanoprost (n=24) and fixed-combination latanoprost/timolol (n=16) clinical trials conducted from November 1992 through November 2007 and ... Read more >>

Br J Ophthalmol (The British journal of ophthalmology)
[2011, 95(11):1490-1495]

Cited: 7 times

View full text PDF listing >>



Fixed combination of latanoprost and timolol vs individual components for primary open-angle glaucoma or ocular hypertension: a randomized, double-masked study.

Eve J Higginbotham, Kenneth W Olander, Elizabeth E Kim, John W Grunden, Kenneth K Kwok, Charles S Tressler, ,

<h4>Objective</h4>To assess the efficacy and safety of fixed-combination latanoprost-timolol (FCLT) vs latanoprost or timolol monotherapy.<h4>Methods</h4>This 12-week, randomized, double-masked, parallel-group study included patients with open-angle glaucoma or ocular hypertension treated with a beta-blocker and with baseline intraocular pressure (IOP) of 26 through 36 mm Hg. Following washout, eligible patients were randomized ... Read more >>

Arch Ophthalmol (Archives of ophthalmology (Chicago, Ill. : 1960))
[2010, 128(2):165-172]

Cited: 24 times

View full text PDF listing >>



A 12-week, randomized, double-masked study of fixed combination latanoprost/timolol versus latanoprost or timolol monotherapy.

Paul Palmberg, Elizabeth E Kim, Kenneth K Kwok, Charles S Tressler, ,

<h4>Purpose</h4>To evaluate the efficacy and safety of fixed combination latanoprost/timolol versus latanoprost or timolol monotherapy.<h4>Methods</h4>This 12-week, randomized, double-masked study was designed to overcome potential shortcomings of previous trials. We enrolled 788 subjects with open-angle glaucoma or ocular hypertension treated with a beta-blocker for > or = 4 weeks before screening. ... Read more >>

Eur J Ophthalmol (European journal of ophthalmology)
[2010, 20(4):708-718]

Cited: 14 times

View full text PDF listing >>





Advertisement


Disclaimer

1.6528 s