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Molecular determinants of therapy response of venetoclax-based combinations in acute myeloid leukemia.

Philipp Makowka, Verena Stolp, Karoline Stoschek, Hubert Serve,

Acute myeloid leukemia (AML) is a heterogeneous, highly malignant disease of the bone marrow. After decades of slow progress, recent years saw a surge of novel agents for its treatment. The most recent advancement is the registration of the Bcl-2 inhibitor ventoclax in combination with a hypomethylating agent (HMA) in ... Read more >>

Biol Chem (Biological chemistry)
[2021, 402(12):1547-1564]

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