Full Text Journal Articles by
Author Karl Ludwig Schulte

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Early outcomes of patients with chronic kidney disease after revascularization for critical limb ischemia.

Asimakis Gkremoutis, Theodosios Bisdas, Giovanni Torsello, Thomas Schmitz-Rixen, Nikolaos Tsilimparis, Konstantinos Stavroulakis, ,

<h4>Background</h4>The aim of this study was to report early outcomes of patients with non-dialysis-dependent chronic kidney disease (NDD-CKD) after revascularization for critical limb-threatening ischemia (CLTI).<h4>Methods</h4>Perioperative data of patients from the CRITISCH (critical limb ischemia) Registry, who also had NDD-CKD (stages 3 and 4), were compared to their counterparts with normal ... Read more >>

J Cardiovasc Surg (Torino) (The Journal of cardiovascular surgery)
[2021, 62(2):104-110]

Cited: 0 times

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Bypass Grafting vs Endovascular Therapy in Patients With Non-Dialysis-Dependent Chronic Kidney Disease and Chronic Limb-Threatening Ischemia (CRITISCH Registry).

Konstantinos Stavroulakis, Asimakis Gkremoutis, Matthias Borowski, Giovanni Torsello, Dittmar Böckler, Thomas Zeller, Markus Steinbauer, Nikolaos Tsilimparis, Theodosios Bisdas, ,

Purpose: To report the outcomes of bypass grafting (BG) vs endovascular therapy (EVT) in patients with non-dialysis-dependent chronic kidney disease (CKD) and chronic limb-threatening ischemia (CLTI). Materials and Methods: The CRITISCH Registry is a prospective, national, interdisciplinary, multicenter registry evaluating the current practice of all available treatment options in 1200 ... Read more >>

J Endovasc Ther (Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists)
[2020, 27(4):599-607]

Cited: 1 time

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Real-world outcomes of endovascular treatment in a non-selected population with peripheral artery disease - prospective study with 2-year follow-up.

Karl-Ludwig Schulte, David Hardung, Christiane Tiefenbacher, Thomas Weiss, Ulrich Hoffmann, Klaus Amendt, Gunnar Tepe, Lothar Heuser, Andras Treszl, Hans-Joachim Lau, Thomas Pfannebecker, Karl Wegscheider,

<i>Background:</i> The study aimed to evaluate the outcomes of percutaneous transluminal angioplasty (PTA) in lower-extremity peripheral artery disease (PAD) patients. <i>Patients and methods:</i> A multi-centre, observational study was performed with 32 German and Austrian centres contributing data to the PTA registry. Data of 1,781 patients with lower-leg and pelvic PAD ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2019, 48(5):433-441]

Cited: 2 times

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Balloon-Expandable Vascular Covered Stent in the Treatment of Iliac Artery Occlusive Disease: 9-Month Results from the BOLSTER Multicenter Study.

John R Laird, Thomas Zeller, Andrew Holden, Dierk Scheinert, Erin Moore, Robert Mendes, Rainer Schmiedel, Richard Settlage, Alexandra Lansky, Michael R Jaff, ,

<h4>Purpose</h4>This study sought to assess the performance of the LIFESTREAM balloon-expandable covered stent for the treatment of iliac artery atherosclerotic lesions.<h4>Methods</h4>A total of 155 patients were treated in a prospective, single-arm study at 17 centers in the United States, Europe, and New Zealand. The primary endpoint was a composite of ... Read more >>

J Vasc Interv Radiol (Journal of vascular and interventional radiology : JVIR)
[2019, 30(6):836-844.e1]

Cited: 1 time

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Outcomes of dialysis patients with critical limb ischemia after revascularization compared with patients with normal renal function.

Alexander Meyer, Cornelia Fiessler, Konstantinos Stavroulakis, Giovanni Torsello, Theodosios Bisdas, Werner Lang, ,

An analysis was conducted of intermediate outcomes and possible influencing factors in patients with end-stage renal disease (ESRD) and critical limb ischemia after lower limb revascularization compared with patients with regular renal function (non-ESRD).Data collection was performed by inquiry of the German multicenter registry of First-Line Treatments in Patients with ... Read more >>

J Vasc Surg (Journal of vascular surgery)
[2018, 68(3):822-829.e1]

Cited: 1 time

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One-Year Results of First-Line Treatment Strategies in Patients With Critical Limb Ischemia (CRITISCH Registry).

Konstantinos Stavroulakis, Matthias Borowski, Giovanni Torsello, Theodosios Bisdas, ,

<h4>Purpose</h4>To examine the outcomes of all first-line strategies for the treatment of critical limb ischemia (CLI), identify factors that influenced the treatment choice, and determine the risk of amputation or death after each treatment.<h4>Methods</h4>CRITISCH ( ClinicalTrials.gov identifier NCT01877252) is a multicenter, national, prospective registry evaluating all available treatment strategies applied ... Read more >>

J Endovasc Ther (Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists)
[2018, 25(3):320-329]

Cited: 4 times

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Association between statin therapy and amputation-free survival in patients with critical limb ischemia in the CRITISCH registry.

Konstantinos Stavroulakis, Matthias Borowski, Giovanni Torsello, Theodosios Bisdas, ,

<h4>Objective</h4>Secondary prevention in patients with critical limb ischemia (CLI) is crucial for the reduction of cardiovascular morbidity and mortality. Nonetheless, current recommendations are extrapolated from other high-risk populations because of the lack of CLI-dedicated trials. The aim of this explorative study was to evaluate the association of statin therapy with ... Read more >>

J Vasc Surg (Journal of vascular surgery)
[2017, 66(5):1534-1542]

Cited: 8 times

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Credentialing in interventional therapy in Europe - comparison of curricula including endovascular therapy of arterial diseases.

Karl-Ludwig Schulte, Pia M Jungmann, Vladimir Makaloski, Lino Goncalves, Markus Steinbauer, Susanne Vonberg, Beatrix B Doerr, Ralf Langhoff, Frederic Baumann,

The prevalence of peripheral artery disease (PAD) is continuously increasing. In addition, the treatment of PAD has changed substantially over the last decades. Novel treatment modalities and diagnostic tools were developed and endovascular therapy was established as a first-line therapy. In consequence, vascular medicine has become an interdisciplinary field, involving ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2017, 46(3):169-176]

Cited: 0 times

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Endovascular Therapy Versus Bypass Surgery as First-Line Treatment Strategies for Critical Limb Ischemia: Results of the Interim Analysis of the CRITISCH Registry.

Theodosios Bisdas, Matthias Borowski, Konstantinos Stavroulakis, Giovanni Torsello, ,

<h4>Objectives</h4>The most effective first-line treatment between endovascular therapy and bypass surgery for patients with critical limb ischemia (CLI) is still not well defined. The primary aim of the interim analysis of CRITISCH (Registry of First-Line Treatments in Patients With Critical Limb Ischemia) was to compare both treatment options in a ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2016, 9(24):2557-2565]

Cited: 16 times

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Current management of renal artery stenosis.

Tomas Lenz, Karl-Ludwig Schulte,

Severe renal artery stenosis may cause renovascular hypertension; in case of bilateral narrowing or in a stenotic solitary kidney, renal insufficiency (e.g. ischemic kidney disease) or pulmonary flash edema may ensue. Renal artery stenosis can be treated by revasularization, using either percutaneous angioplasty (with or without stenting) or less common ... Read more >>

Panminerva Med (Panminerva medica)
[2016, 58(1):94-101]

Cited: 1 time

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In-hospital outcomes in patients with critical limb ischemia and end-stage renal disease after revascularization.

Alexander Meyer, Werner Lang, Matthias Borowski, Giovanni Torsello, Theodosios Bisdas, ,

<h4>Objective</h4>Analysis of in-hospital outcomes in patients treated for critical limb ischemia (CLI) and end-stage renal disease (ESRD) compared to CLI patients with normal renal function.<h4>Methods</h4>A subgroup analysis of the German CRITISCH registry, a prospective multicenter registry, assessing the first-line treatment strategies in CLI patients in 27 vascular centers in Germany ... Read more >>

J Vasc Surg (Journal of vascular surgery)
[2016, 63(4):966-973]

Cited: 12 times

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Current practice of first-line treatment strategies in patients with critical limb ischemia.

Theodosios Bisdas, Matthias Borowski, Giovanni Torsello, ,

<h4>Objective</h4>Critical limb ischemia (CLI) is growing in global prevalence and is associated with high rates of limb loss and mortality. However, a relevant gap of evidence about the most optimal treatment strategy still exists. The aim of this study of the prospective, multicenter First-Line Treatments in Patients With Critical Limb ... Read more >>

J Vasc Surg (Journal of vascular surgery)
[2015, 62(4):965-973.e3]

Cited: 23 times

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[Renal denervation in refractory hypertension: joint statement of the German hypertension league DHL eV and the German societies of cardiology, angiology, nephrology and radiology].

Oliver Vonend, Michael Böhm, Siegfried Eckert, Martin Hausberg, Harald Rittger, Lars-Christian Rump, Roland Schmieder, Karl-Ludwig Schulte, Heribert Schunkert, Michael Uder, Roland Veelken, Dierk Vorwerk, Joachim Weil, Ulrich Wenzel, Felix Mahfoud,

Arterial hypertension is a major risk factor for cardiovascular mortality and remains insufficiently controlled in Germany. The sham controlled Symplicity HTN-3 trial did meet its primary safety endpoint but failed to meet its primary efficacy endpoint. Renal denervation can not replace established, well-proven therapies. It can only be used in ... Read more >>

Dtsch Med Wochenschr (Deutsche medizinische Wochenschrift (1946))
[2015, 140(5):363]

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Paclitaxel-Coated Balloon in Infrapopliteal Arteries: 12-Month Results From the BIOLUX P-II Randomized Trial (BIOTRONIK'S-First in Man study of the Passeo-18 LUX drug releasing PTA Balloon Catheter vs. the uncoated Passeo-18 PTA balloon catheter in subjects requiring revascularization of infrapopliteal arteries).

Thomas Zeller, Ulrich Beschorner, Ernst Pilger, Marc Bosiers, Koen Deloose, Patrick Peeters, Dierk Scheinert, Karl-Ludwig Schulte, Aljoscha Rastan, Marianne Brodmann,

<h4>Objectives</h4>The aim of BIOLUX P-II (BIOTRONIK'S-First in Man study of the Passeo-18 LUX drug releasing PTA Balloon Catheter vs. the uncoated Passeo-18 PTA balloon catheter in subjects requiring revascularization of infrapopliteal arteries) trial was to compare the safety and efficacy of a novel paclitaxel-coated drug-eluting balloon (DEB) versus an uncoated ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2015, 8(12):1614-1622]

Cited: 44 times

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Primary Self-EXPANDing Nitinol Stenting vs Balloon Angioplasty With Optional Bailout Stenting for the Treatment of Infrapopliteal Artery Disease in Patients With Severe Intermittent Claudication or Critical Limb Ischemia (EXPAND Study).

Karl-Ludwig Schulte, Ernst Pilger, Sebastian Schellong, Kong Ten Tan, Frederic Baumann, Ralf Langhoff, Giovanni Torsello, Thomas Zeller, Klaus Amendt, Marianne Brodmann, ,

<h4>Purpose</h4>To compare primary placement of a self-expanding nitinol stent to percutaneous transluminal angioplasty (PTA) with bailout stenting in infrapopliteal arteries of patients with severe intermittent claudication or critical limb ischemia (CLI).<h4>Methods</h4>In the EXPAND trial (ClinicalTrials.gov; identifier NCT00906022), 92 patients (mean age 72.9±9.5 years; 62 men) undergoing treatment for infrapopliteal stenosis ... Read more >>

J Endovasc Ther (Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists)
[2015, 22(5):690-697]

Cited: 15 times

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Paclitaxel-releasing balloon in femoropopliteal lesions using a BTHC excipient: twelve-month results from the BIOLUX P-I randomized trial.

Dierk Scheinert, Karl-Ludwig Schulte, Thomas Zeller, Johannes Lammer, Gunnar Tepe,

<h4>Purpose</h4>To evaluate the safety and efficacy of the novel Passeo-18 Lux paclitaxel-coated balloon compared with the Passeo-18 uncoated balloon in patients with symptomatic de novo or restenotic femoropopliteal lesions.<h4>Methods</h4>Sixty patients (34 men; mean age 70.7 ± 10.1 years) in 5 European centers were enrolled in the BIOLUX P-I trial (ClinicalTrials.gov ... Read more >>

J Endovasc Ther (Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists)
[2015, 22(1):14-21]

Cited: 50 times

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[Is an age-adjusted D-dimer cut-off value more accurate?--Age-adjusted D-dimer cut-off values clearly increase specificity].

David Hardung, Karl-Ludwig Schulte,

Dtsch Med Wochenschr (Deutsche medizinische Wochenschrift (1946))
[2013, 138(30):1500]

Cited: 0 times

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German multicenter real-world registry of stenting for superficial femoral artery disease: clinical results and predictive factors for revascularization.

Hans Krankenberg, Thilo Tübler, Sebastian Sixt, Matthias Fischer, Rainer Schmiedel, Karl-Ludwig Schulte, Jörn O Balzer, Arne Kieback, Eduard Fiehn, Günther Wittenberg, Tammam Ali, Christiane Tiefenbacher, Thomas Jahnke, Hermann J Steinkamp, Karl Wegscheider, András Treszl, Maja Ingwersen, Thomas Zeller,

<h4>Purpose</h4>To investigate nitinol stent treatment of superficial femoral artery (SFA) lesions and the impact of different risk factors on the need for clinically driven target lesion revascularization (TLR) in a large, real-world population of claudicants.<h4>Methods</h4>Patients presenting with symptomatic SFA stenosis >70% were consecutively enrolled in the 13-center MARIS prospective registry ... Read more >>

J Endovasc Ther (Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists)
[2014, 21(4):463-471]

Cited: 12 times

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Therapy-centered classification of peripheral arterial disease.

Gerhard Rümenapf, Peter Huppert, Karl-Ludwig Schulte, Holger Lawall,

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2014, 43(1):3-5]

Cited: 0 times

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Non-coronary atherosclerosis.

Augusto Gallino, Victor Aboyans, Curt Diehm, Francesco Cosentino, Hans Stricker, Erling Falk, Olaf Schouten, John Lekakis, Beatrice Amann-Vesti, Francesco Siclari, Pavel Poredos, Salvatore Novo, Marianne Brodmann, Karl-Ludwig Schulte, Charalambos Vlachopoulos, Raffaele De Caterina, Peter Libby, Iris Baumgartner, ,

During the last decades, the clinical and research interest in atherosclerosis has been mostly focused on coronary arteries. After the publications of the European Society Guidelines and AHA/ACC Guidelines on Peripheral artery diseases, and of the Registry REduction in Atherothrombosis for Continued Health Registry, there has been an increased interest ... Read more >>

Eur Heart J (European heart journal)
[2014, 35(17):1112-1119]

Cited: 37 times

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MISAGO 2: one-year outcomes after implantation of the Misago self-expanding nitinol stent in the superficial femoral and popliteal arteries of 744 patients.

Karl-Ludwig Schulte, Ivan Kralj, Hans Martin Gissler, Luis Alberto Bagnaschino, Ivo Buschmann, Jean-Marc Pernès, Patrick Haage, Peter Goverde, Jean-Paul Beregi, Martin Válka, Jaroslav Boudny, Thomas Geibel, Marek Velkoborsky, Markus Zähringer, Christian Paetzel, Fabrizio Fanelli, Stefan Müller-Hülsbeck, Thomas Zeller, Ralf Langhoff,

<h4>Purpose</h4>To evaluate the safety and efficacy of the Misago self-expanding rapid-exchange nitinol stent system for the treatment of femoropopliteal occlusive disease in a prospective multicenter observational trial (ClinicalTrials.gov; identifier NCT01118117).<h4>Methods</h4>Between April and October 2008, the registry enrolled 744 patients (496 men; 69 ± 10 years) who had symptomatic ≥ 70% ... Read more >>

J Endovasc Ther (Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists)
[2012, 19(6):774-784]

Cited: 24 times

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The diagnosis, treatment and follow-up of extracranial carotid stenosis.

Hans-Henning Eckstein, Andreas Kühnl, Arnd Dörfler, Ina B Kopp, Holger Lawall, Peter A Ringleb, ,

<h4>Background</h4>Extracranial atherosclerotic lesions of the carotid bifurcation cause 10% to 20% of all cases of cerebral ischemia. Until now, there have been no comprehensive evidence- and consensus-based recommendations for the management of patients with extracranial carotid stenosis in Germany and Austria.<h4>Methods</h4>The literature was systematically searched for pertinent publications (1990-2011). On ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2013, 110(27-28):468-476]

Cited: 34 times

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Is there a need for training standards and credentialing in interventional therapy of arterial vascular diseases?

Karl-Ludwig Schulte,

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2012, 41(6):391-393]

Cited: 0 times

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[Management of digital ulcers in patients with systemic sclerosis].

G Riemekasten, U Hoffmann, C Sunderkötter, N Weiss, A Kuhn, ,

Dtsch Med Wochenschr (Deutsche medizinische Wochenschrift (1946))
[2012, 137(1-2):34-40]

Cited: 6 times

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Reocclusion caused by stent fracture implanted in the subclavian artery ostium: a case report.

Norihiko Shinozaki, Ralf Langhoff, Karl-Ludwig Schulte,

A 47 year-old male, a woodcutter by profession, complained of severe pain in the left arm during physical stress. Eighteen months ago, a balloon-expandable stainless steel stent had been implanted in the left subclavian artery ostium. The angiography revealed a stent fracture at the origin of the left subclavian artery, this ... Read more >>

Cardiovasc Interv Ther (Cardiovascular intervention and therapeutics)
[2013, 28(1):111-114]

Cited: 1 time

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