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Author Junjie Pan

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Efficacy and safety of nitrate supplementation on exercise tolerance in chronic obstructive pulmonary disease: A systematic review and meta-analysis.

Hongkuan Yang, Shuifeng He, Fang Chen, Linbao Liang, Junjie Pan,

<h4>Background</h4>Exercise intolerance was prevalent in people with chronic obstructive pulmonary disease (COPD) and had a detrimental effect on the quality of life. We aimed to evaluate the efficacy and safety of nitrate supplementation in exercise tolerance of people with COPD.<h4>Methods</h4>We searched medical databases including Cochrane Library, EMBASE, and PubMed from ... Read more >>

Medicine (Baltimore) (Medicine)
[2022, 101(2):e28578]

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WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity.

Guohui Zhong, Dingsheng Zhao, Jianwei Li, Zifan Liu, Junjie Pan, Xinxin Yuan, Wenjuan Xing, Yinglong Zhao, Shukuan Ling, Yingxian Li,

Cardiac muscle is extremely sensitive to changes in loading conditions; the microgravity during space flight can cause cardiac remodeling and function decline. At present, the mechanism of microgravity-induced cardiac remodeling remains to be revealed. WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is an important activator of pressure overload-induced cardiac ... Read more >>

Front Cell Dev Biol (Frontiers in cell and developmental biology)
[2021, 9:739944]

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3' untranslated region of Ckip-1 inhibits cardiac hypertrophy independently of its cognate protein.

Yinlong Zhao, Shukuan Ling, Jianwei Li, Guohui Zhong, Ruikai Du, Youyou Li, Yanqing Wang, Caizhi Liu, Xiaoyan Jin, Wei Liu, Tong Liu, Yuheng Li, Dingsheng Zhao, Weijia Sun, Zizhong Liu, Zifan Liu, Junjie Pan, Xinxin Yuan, Xingcheng Gao, Wenjuan Xing, Yan-Zhong Chang, Yingxian Li,

<h4>Aims</h4>3' untranslated region (3' UTR) of mRNA is more conserved than other non-coding sequences in vertebrate genomes, and its sequence space has substantially expanded during the evolution of higher organisms, which substantiates their significance in biological regulation. However, the independent role of 3' UTR in cardiovascular disease was largely unknown.<h4>Methods ... Read more >>

Eur Heart J (European heart journal)
[2021, 42(36):3786-3799]

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Targeting E3 Ubiquitin Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination.

Dingsheng Zhao, Guohui Zhong, Jianwei Li, Junjie Pan, Yinlong Zhao, Hailin Song, Weijia Sun, Xiaoyan Jin, Yuheng Li, Ruikai Du, Jielin Nie, Tong Liu, Junmeng Zheng, Yixin Jia, Zifan Liu, Wei Liu, Xinxin Yuan, Zizhong Liu, Jinping Song, Guanghan Kan, Youyou Li, Caizhi Liu, Xingcheng Gao, Wenjuan Xing, Yan-Zhong Chang, Yingxian Li, Shukuan Ling,

<h4>Background</h4>Without adequate treatment, pathological cardiac hypertrophy induced by sustained pressure overload eventually leads to heart failure. WWP1 (WW domain-containing E3 ubiquitin protein ligase 1) is an important regulator of aging-related pathologies, including cancer and cardiovascular diseases. However, the role of WWP1 in pressure overload-induced cardiac remodeling and heart failure is ... Read more >>

Circulation (Circulation)
[2021, 144(9):694-711]

Cited: 2 times

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WWP1 deficiency protects from cardiac remodeling induced by simulated microgravity

Guohui Zhong, Dingsheng Zhao, Jianwei Li, Zifan Liu, Junjie Pan, Xinxin Yuan, Wenjuan Xing, Yinglong Zhao, Shukuan Ling, Yingxian Li,

Cardiac muscle is extremely sensitive to changes in loading conditions, the microgravity during space flight can cause cardiac remodeling and function decline. At present, the mechanism of microgravity-induced cardiac remodeling remains to be revealed. WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is an important activator of pressure-overload induced cardiac ... Read more >>

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Characteristics of pre-metastatic niche: the landscape of molecular and cellular pathways.

Hao Wang, Junjie Pan, Livnat Barsky, Jule Caroline Jacob, Yan Zheng, Chao Gao, Shun Wang, Wenwei Zhu, Haoting Sun, Lu Lu, Huliang Jia, Yue Zhao, Christiane Bruns, Razi Vago, Qiongzhu Dong, Lunxiu Qin,

Metastasis is a major contributor to cancer-associated deaths. It involves complex interactions between primary tumorigenic sites and future metastatic sites. Accumulation studies have revealed that tumour metastasis is not a disorderly spontaneous incident but the climax of a series of sequential and dynamic events including the development of a pre-metastatic ... Read more >>

Mol Biomed (Molecular biomedicine)
[2021, 2(1):3]

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Dopants fixation of Ruthenium for boosting acidic oxygen evolution stability and activity.

Shaoyun Hao, Min Liu, Junjie Pan, Xiangnan Liu, Xiaoli Tan, Nan Xu, Yi He, Lecheng Lei, Xingwang Zhang,

Designing highly durable and active electrocatalysts applied in polymer electrolyte membrane (PEM) electrolyzer for the oxygen evolution reaction remains a grand challenge due to the high dissolution of catalysts in acidic electrolyte. Hindering formation of oxygen vacancies by tuning the electronic structure of catalysts to improve the durability and activity ... Read more >>

Nat Commun (Nature communications)
[2020, 11(1):5368]

Cited: 1 time

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The Chimonanthus salicifolius genome provides insight into magnoliid evolution and flavonoid biosynthesis.

Qundan Lv, Jie Qiu, Jie Liu, Zheng Li, Wenting Zhang, Qin Wang, Jie Fang, Junjie Pan, Zhengdao Chen, Wenliang Cheng, Michael S Barker, Xuehui Huang, Xin Wei, Kejun Cheng,

Chimonanthus salicifolius, a member of the Calycanthaceae of magnoliids, is one of the most famous medicinal plants in Eastern China. Here, we report a chromosome-level genome assembly of C. salicifolius, comprising 820.1 Mb of genomic sequence with a contig N50 of 2.3 Mb and containing 36 651 annotated protein-coding genes. Phylogenetic analyses revealed that ... Read more >>

Plant J (The Plant journal : for cell and molecular biology)
[2020, 103(5):1910-1923]

Cited: 6 times

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A Novel Risk Classification Model Predicts Overall Survival and Locoregional Surgery Benefit in Colorectal Patients with Distant Metastasis at the Initial Diagnosis

Mo Chen, Tian-en Li, Pei-zhun Du, Junjie Pan, Zheng Wang, Dayu Huang, Xuan Wang,

<h4>Background: </h4> and aims : In this research, we aimed to construct a risk classification model to predict overall survival (OS) and locoregional surgery benefit in colorectal cancer (CRC) patients with distant metastasis. <h4>Methods: </h4> We selected a cohort consisting of 12741 CRC patients diagnosed with distant metastasis between 2010 ... Read more >>

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Ultrasensitive, flexible, and low-cost nanoporous piezoresistive composites for tactile pressure sensing.

Jing Li, Santiago Orrego, Junjie Pan, Peisheng He, Sung Hoon Kang,

Highly sensitive flexible tactile sensors are of continuing interest for various applications including wearable devices, human-machine interface systems, and internet of things. Current technologies for high sensitivity piezoresistive sensors rely on costly materials and/or fabrication methods such as graphene-based and micro-structured composites limiting accessibility and scalability. Here, we report a ... Read more >>

Nanoscale (Nanoscale)
[2019, 11(6):2779-2786]

Cited: 3 times

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Patterns of Extrathoracic Metastases in Different Histological Types of Lung Cancer.

Xuan Wang, Zheng Wang, Junjie Pan, Zhou-Yi Lu, Dong Xu, Hui-Jun Zhang, Shao-Hua Wang, Da-Yu Huang, Xiao-Feng Chen,

Lung cancer is the leading cause of cancer-related deaths mainly attributable to metastasis, especially extrathoracic metastasis. This large-cohort research is aimed to explore metastatic profiles in different histological types of lung cancer, as well as to assess clinicopathological and survival significance of diverse metastatic lesions. Lung cancer cases were extracted ... Read more >>

Front Oncol (Frontiers in oncology)
[2020, 10:715]

Cited: 5 times

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Pattern of distant metastases in inflammatory breast cancer - A large-cohort retrospective study.

Zheng Wang, Mo Chen, Junjie Pan, Xuan Wang, Xiao-Song Chen, Kun-Wei Shen,

Inflammatory breast cancer (IBC) is a fatal form of breast cancer. IBC patients present with unfavorable prognosis mainly attributable to high risk of distant metastasis. Thus, in this cohort study, we aimed to explore metastatic profiles of different molecular subtypes of IBC and elucidate the clinical and prognostic characteristics among ... Read more >>

J Cancer (Journal of Cancer)
[2020, 11(2):292-300]

Cited: 7 times

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A Facile Route for Constructing Effective Cu-Nx Active Sites for Oxygen Reduction Reaction.

Jingjing Li, Wei Xia, Tao Wang, Lirong Zheng, Yue Lai, Junjie Pan, Cheng Jiang, Li Song, Mengyu Wang, Huting Zhang, Na Chen, Guang Chen, Jianping He,

The coordination number between copper and nitrogen in copper/nitrogen-based electrocatalysts is important for boosting the oxygen reduction reaction (ORR). However, it is difficult to control unsaturated copper/nitrogen constructions as well as to compare their ORR performances in similar carbon matrices in a simple yet efficient manner. In this study, we ... Read more >>

Chemistry (Chemistry (Weinheim an der Bergstrasse, Germany))
[2019, :]

Cited: 2 times

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Stretchable and Highly Sensitive Braided Composite [email protected]@Polypyrrole for Wearable Applications.

Junjie Pan, Mengyun Yang, Lei Luo, Anchang Xu, Bin Tang, Deshan Cheng, Guangming Cai, Xin Wang,

Flexible wearable devices for various applications have attracted research attention in recent years. To date, it is still a big challenge to fabricate strain sensors with a large workable strain range while maintaining their high sensitivity. Herein, we report the fabrication of highly sensitive wearable strain sensors from braided composite ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2019, 11(7):7338-7348]

Cited: 2 times

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Exosomes derived from miR-146a-modified adipose-derived stem cells attenuate acute myocardial infarction-induced myocardial damage via downregulation of early growth response factor 1.

Junjie Pan, Maimaitijiang Alimujiang, Qiying Chen, Haiming Shi, Xinping Luo,

Multiple studies demonstrated that early growth response factor 1 (EGR1) induces myocardial damage after acute myocardial infarction (AMI). Recent evidence indicates that microRNAs (miRNA) play an important role in exosome-mediated cardioprotection after AMI. Bioinformatics analysis has shown that miR-146a can regulate the expression of EGR1, so the aim of this ... Read more >>

J Cell Biochem (Journal of cellular biochemistry)
[2019, 120(3):4433-4443]

Cited: 34 times

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Large-Scale Production of Highly Stretchable CNT/Cotton/Spandex Composite Yarn for Wearable Applications.

Guangming Cai, Mengyun Yang, Junjie Pan, Deshan Cheng, Zhigang Xia, Xin Wang, Bin Tang,

Incorporation of carbon nanotubes (CNTs) into textiles without sacrificing their intrinsic properties provides a promising platform in exploring wearable technology. However, manufacture of flexible, durable, and stretchable CNT/textile composites on an industrial scale is still a great challenge. We hereby report a facile way of incorporating CNTs into the traditional ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2018, 10(38):32726-32735]

Cited: 2 times

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[Correlation between expressions of myeloperoxidase and eosinophil cationic protein in sputum and clinical features of asthma-chronic obstructive pulmonary disease overlap].

Hongkuan Yang, Yan Zhang, Jiaying Zhang, Junjie Pan, Fang Wang, Xuping Luo, Fang Chen,

<h4>Objective</h4>To observe the role of myeloperoxidase(MPO)and eosinophilic cationic protein(ECP)in the airway inflammation and their correlation with clinical feature in asthma-COPD overlap (ACO) patients.<h4>Methods</h4>Twenty patients with COPD, 20 with asthma, 20 with ACO and 20 control subjects underwent pulmonary function test for measurement of forced expiratory volume in 1 second (FEV<sub>1</sub>), ... Read more >>

Nan Fang Yi Ke Da Xue Xue Bao (Nan fang yi ke da xue xue bao = Journal of Southern Medical University)
[2018, 38(10):1215-1221]

Cited: 1 time

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Conductive Cotton Fabrics for Motion Sensing and Heating Applications.

Mengyun Yang, Junjie Pan, Anchang Xu, Lei Luo, Deshan Cheng, Guangming Cai, Jinfeng Wang, Bin Tang, Xungai Wang,

Conductive cotton fabric was prepared by coating single-wall carbon nanotubes (CNTs) on a knitted cotton fabric surface through a "dip-and-dry" method. The combination of CNTs and cotton fabric was analyzed using scanning electron microscopy (SEM) and Raman scattering spectroscopy. The CNTs coating improved the mechanical properties of the fabric and ... Read more >>

Polymers (Basel) (Polymers)
[2018, 10(6):]

Cited: 7 times

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Switching the electromagnetic properties of multicomponent porous carbon materials derived from bimetallic metal-organic frameworks: effect of composition.

Wei Liu, Junjie Pan, Guangbin Ji, Xiaohui Liang, Yan Cheng, Bin Quan, Youwei Du,

Porous carbon materials have long been regarded as promising candidate for high-performance lightweight microwave absorption materials owing to their strong attenuation abilities, tunable dielectric properties and low density. Nevertheless, previous work mainly focused on binary composites (usually carbon and magnetic fillers), which show limited loss mechanisms. The effect (except temperature) ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2017, 46(11):3700-3709]

Cited: 8 times

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Essential thrombocythemia presenting as acute coronary syndrome: case reports and literature review.

Nanqing Xiong, Wen Gao, Junjie Pan, Xinping Luo, Haiming Shi, Jian Li,

For the patients with essential thrombocythemia (ET), systemic thrombosis presents as one of the most dangerous complications. It's been widely accepted that acute coronary syndrome (ACS) is a kind of thrombotic diseases. However, there are very few case reports about ET first presenting as ACS. For some patients diagnosed as ... Read more >>

J Thromb Thrombolysis (Journal of thrombosis and thrombolysis)
[2017, 44(1):57-62]

Cited: 1 time

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[Preparation of a novel AAV-ITR gene expression mini vector in Sf9 insect cells via baculovirus].

Taiming Li, Junjie Pan, Jing Qi, Chun Zhang,

AAV-ITR gene expression mini vector is a double-strand or single-strand DNA that only contains inverted terminal repeats of adeno-associated virus, cis-elements and gene of interest and does not contain any other foreign DNA sequences. We prepared Bac-ITR-EGFP and Bac-inrep. Spodoptera frugiperda cells were infected with Bac-ITR-EGFP (P3) and Bac-inrep (P3). ... Read more >>

Sheng Wu Gong Cheng Xue Bao (Sheng wu gong cheng xue bao = Chinese journal of biotechnology)
[2015, 31(8):1230-1238]

Cited: 0 times

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Conditional knockout of tissue factor pathway inhibitor 2 in vascular endothelial cells accelerates atherosclerotic plaque development in mice.

Jin Hong, Rongle Liu, Lewen Chen, Bangwei Wu, Jia Yu, Wen Gao, Junjie Pan, Xinping Luo, Haiming Shi,

<h4>Background</h4>Tissue factor pathway inhibitor-2 (TFPI-2) regulates matrix metalloproteinases activation and extracellular matrix degradation. Over-expression of TFPI-2 enhances atherosclerotic plaque stability. The aim of this study is to investigate the effect of conditional knockout (KO) of TFPI-2 in vascular endothelial cells on the initiation and development of atherosclerotic plaque.<h4>Methods</h4>A Cre/mloxP conditional ... Read more >>

Thromb Res (Thrombosis research)
[2016, 137:148-156]

Cited: 7 times

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Cerebral Activity Changes in Different Traditional Chinese Medicine Patterns of Psychogenic Erectile Dysfunction Patients.

Qi Liu, Peihai Zhang, Junjie Pan, Zhengjie Li, Jixin Liu, Guangsen Li, Wei Qin, Yaodong You, Xujun Yu, Jinbo Sun, Minghao Dong, Qiyong Gong, Jun Guo, Degui Chang,

Background. Pattern differentiation is the foundation of traditional Chinese medicine (TCM) treatment for erectile dysfunction (ED). This study aims to investigate the differences in cerebral activity in ED patients with different TCM patterns. Methods. 27 psychogenic ED patients and 27 healthy subjects (HS) were enrolled in this study. Each participant ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2015, 2015:503536]

Cited: 7 times

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Rapid baculovirus titration assay based on viable cell side scatter (SSC).

Jing Qi, Tao Liu, Junjie Pan, Peng Miao, Chun Zhang,

The baculovirus expression system is one of the most powerful tools for the production of recombinant proteins on both laboratory and industrial scales. Multiplicity of infection (MOI) is the crucial parameter for efficient protein expression. To obtain an optimal MOI, it is important to determine titer of virus stock before ... Read more >>

Anal Chim Acta (Analytica chimica acta)
[2015, 879:58-62]

Cited: 4 times

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ST-segment elevation myocardial infarction in patient with essential thrombocythemia without associated risk.

Wen Gao, Wei Shen, Xinping Luo, Haiming Shi, Xiaofei Jiang, Junjie Pan,

Int J Cardiol (International journal of cardiology)
[2015, 180:223-225]

Cited: 3 times

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