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Mycoplasma ovipneumoniae induces caspase-8-dependent extrinsic apoptosis and p53- and ROS-dependent intrinsic apoptosis in murine alveolar macrophages.

Jing Chen, Yi Zhou, Erpeng Zhu, Peng Yang, Mei Li, Shuangxiang Zhang, Jun Yue, Ming Wen, Kaigong Wang, Zhentao Cheng,

<i>Mycoplasma ovipneumoniae (MO)</i> is a principle causative agent of chronic respiratory disease in ruminants, including sheep, goats, and deer, posing a great threat to the ruminant industry worldwide. However, the pathogenesis of <i>MO</i> infection still remains not well understood and needs further clarification. Here we report a time-dependent apoptosis in ... Read more >>

Virulence (Virulence)
[2021, 12(1):2703-2720]

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A fowl adenovirus serotype 4 (FAdV-4) Fiber2 subunit vaccine candidate provides complete protection against challenge with virulent FAdV-4 strain in chickens.

Dejing Yin, Ling He, Erpeng Zhu, Tian Fang, Jun Yue, Ming Wen, Kaigong Wang, Zhentao Cheng,

Hypervirulent fowl adenovirus serotype 4 (FAdV-4)-induced hepatitis-hydropericardium syndrome (HHS) with high mortality causes huge economic losses to the poultry industry worldwide. However, commercially available vaccines against FAdV-4 infection remain scarce. Here, we prepared a subunit vaccine candidate derived from the bacterially expressed recombinant Fiber2 protein (termed as rFiber2 subunit vaccine) ... Read more >>

Vet Microbiol (Veterinary microbiology)
[2021, 263:109250]

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Manganese oxide nanomaterials boost cancer immunotherapy.

Binbin Ding, Jun Yue, Pan Zheng, Ping'an Ma, Jun Lin,

Immunotherapy, a strategy that leverages the host immune function to fight against cancer, plays an increasingly important role in clinical tumor therapy. In spite of the great success achieved in not only clinical treatment but also basic research, cancer immunotherapy still faces many huge challenges. Manganese oxide nanomaterials (MONs), as ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2021, 9(35):7117-7131]

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Autophagy activation promotes the effect of iPSCs-derived NSCs on bladder function restoration after spinal cord injury.

Rongxue Shao, Liang Zhang, Hejie Yang, Yanbin Wang, Zhijing Zhang, Jun Yue, Yipeng Chen, Hao Pan, Hui Zhou, Renfu Quan,

The role of autophagy in the transplantation of induced pluripotent stem cells (iPSCs)-derived neural stem cells (NSCs) to treat spinal cord injury (SCI) and neurogenic bladder was investigated in this study. NSCs derived from human iPSCs were identified by and immunofluorescence assay. To clarify the role of autophagy, iPSCs were ... Read more >>

Tissue Cell (Tissue & cell)
[2021, 72:101596]

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LncRNA-GAS5 promotes spinal cord repair and the inhibition of neuronal apoptosis via the transplantation of 3D printed scaffold loaded with induced pluripotent stem cell-derived neural stem cells.

Rongxue Shao, Changming Li, Yan Chen, Liang Zhang, Hejie Yang, Zhijing Zhang, Jun Yue, Wenshuo Gao, Hang Zhu, Hao Pan, Hui Zhou, Renfu Quan,

<h4>Background</h4>Stem cell transplantation has been increasingly used for spinal cord repair, and some achievements have been made. However, limited stem cell sources as well as immune rejection and ethical issues have restricted its wide application. Therefore, to achieve further breakthroughs regarding the application of stem cell transplantation to treat spinal ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2021, 9(11):931]

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Generation of Reducing Sugars from Corncob by Magnetic Carbon-Based Solid Acid Pretreatment Combined with In Situ Enzymatic Hydrolysis

Si Lu, Qiong Wang, Xiaoman Wang, Cuiyi Liang, Juan Fu, Zihan Xu, Zhongming Wang, Zhenhong Yuan, Jun Yue, Wei Qi,

The efficient conversion of hemicellulose and cellulose in lignocellulosic biomass to reducing sugars remains as one major challenge for the development of biorefinery. In this work, corncob saccharification in the aqueous phase was realized efficiently via pretreatment by magnetic carbon-based solid acid (MMCSA) catalyst, combined with the subsequent in situ ... Read more >>

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Combining Mechanical High-Intensity Focused Ultrasound Ablation with Chemotherapy for Augmentation of Anticancer Immune Responses.

Chao Li, Yao Lu, Lili Cheng, Xiaoge Zhang, Jun Yue, Jie Liu,

As a noninvasive therapy, high-intensity focused ultrasound (HIFU) shows great potential in inducing anticancer immune responses. However, the overall anticancer efficacy of HIFU is still limited due to the rapid attenuation of ultrasound waves and inadequacy of ultrasound waves to spread to the whole tumor. Here, we combined HIFU with ... Read more >>

Mol Pharm (Molecular pharmaceutics)
[2021, 18(5):2091-2103]

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Atomic-engineering Au-Ag nanoalloys for screening antimicrobial agents with low toxicity towards mammalian cells.

Zi Lin, Yao Luo, Pengfei Liu, Yanjun Li, Jun Yue, Lelun Jiang,

Silver nanoparticles (AgNPs) have shown potent antibacterial activity against numerous bacteria strains. However, their toxicity against mammalian cells is still a big challenge, limiting their in vivo applications. Here, we found that alloying Ag and Au in an atomic level to form Au-Ag nanoalloys (NAs) could effectively reduce the cytotoxicity ... Read more >>

Colloids Surf B Biointerfaces (Colloids and surfaces. B, Biointerfaces)
[2021, 204:111831]

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Fourier-Transform-Based Surface Measurement and Reconstruction of Human Face Using the Projection of Monochromatic Structured Light.

Bingquan Chen, Hongsheng Li, Jun Yue, Peng Shi,

This work presents a new approach of surface measurement of human face via the combination of the projection of monochromatic structured light, the optical filtering technique, the polarization technique and the Fourier-transform-based image-processing algorithm. The theoretical analyses and experimental results carried out in this study showed that the monochromatic feature ... Read more >>

Sensors (Basel) (Sensors (Basel, Switzerland))
[2021, 21(7):]

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The G199X and V157fs mutations in the TP53 gene promote malignancy in serous ovarian cancer: an analysis using whole-exome sequencing.

Dan Su, Man Nie, Jun Yue,

<h4>Background</h4>The carcinogenic mechanisms underlying serous ovarian cancer are not fully understood.<h4>Methods</h4>Whole-exome sequencing and targeted sequencing were performed in ovarian cancer samples to identify novel molecular markers involved in the process of cell malignancy in ovarian cancer. <i>In vitro</i> experiments, the oncogenic roles such as cell proliferation, migration and invasion of ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2021, 9(8):710]

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Erythrocytosis and Performance of HbA1c in Detecting Diabetes on an Oxygen-Deficient Plateau: A Population-based Study.

Qian Ren, Xuemei Lv, Lihui Yang, Jun Yue, Yingying Luo, Lingli Zhou, Shuyou Meng, Senlin Yang, Basang Puchi, Xianghai Zhou, Linong Ji,

<h4>Context</h4>The hemoglobin A1c (HbA1c) test is a standard test for diabetes screening and diagnosis.<h4>Objective</h4>To evaluate A1c performance for diabetes screening in high-altitude polycythemia compared to a population with a high proportion of people living in an oxygen-deficient environment.<h4>Design</h4>A population-based epidemiological survey was conducted.<h4>Setting</h4>The cities Lhasa and Shigatse were selected. Volunteers ... Read more >>

J Clin Endocrinol Metab (The Journal of clinical endocrinology and metabolism)
[2020, 105(4):]

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High-Yield 5-Hydroxymethylfurfural Synthesis from Crude Sugar Beet Juice in a Biphasic Microreactor.

Ria M Abdilla-Santes, Wenze Guo, Pieter C A Bruijnincx, Jun Yue, Peter J Deuss, Hero J Heeres,

5-Hydroxymethylfurfural (HMF) is an important biobased platform chemical obtainable in high selectivity by the hydrolysis of fructose (FRC). However, FRC is expensive, making the production of HMF at a competitive market price highly challenging. Here, it is shown that sugar beet thick juice, a crude, sucrose-rich intermediate in sugar refining, ... Read more >>

ChemSusChem (ChemSusChem)
[2019, 12(18):4304-4312]

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Genetic Polymorphisms of miR-149 Associated with Susceptibility to Both Pulmonary and Extrapulmonary Tuberculosis.

Wei-Wei Chen, Baoshan Wan, Ranran Zhang, Wen Cao, Li Liang, Yan-Lin Zhao, Jin Chen, Jun Yue,

<b><i>Background:</i></b> Single nucleotide polymorphisms (SNPs) within precursor microRNAs (miRNAs) can affect the expression of the miRNAs and may be involved in the pathogenesis of pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB). <b><i>Aims:</i></b> We investigated the potential associations among four precursor miRNA SNPs (miR-149 A>G, C>T; miR-196a2 C>T; miR-499 C>T) and both ... Read more >>

Genet Test Mol Biomarkers (Genetic testing and molecular biomarkers)
[2019, 23(7):442-447]

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Quantity and quality variations of dissolved organic matter (DOM) in column leaching process from agricultural soil: Hydrochemical effects and DOM fractionation.

Wenlong Gu, Shuangbing Huang, Shan Lei, Jun Yue, Zhaoxin Su, Fei Si,

Leaching dynamics of dissolved organic matter (DOM) from agricultural soil are influenced by the chemistry of irrigation water. This study used multiple spectroscopy methods to investigate the dynamics of DOM in column leaching process by utilizing selected solutions. DOC was leached out by Na solutions more effectively than by Ca, ... Read more >>

Sci Total Environ (The Science of the total environment)
[2019, 691:407-416]

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Polymorphism in the EREG gene confers susceptibility to tuberculosis.

Wen Cao, Liu-Lin Luo, Wei-Wei Chen, Li Liang, Ran-Ran Zhang, Yan-Lin Zhao, Jin Chen, Jun Yue,

<h4>Background</h4>Host genetic factors affect the immune response to Mycobacterium tuberculosis (Mtb) infection as well as the progression of the disease. Epiregulin (EREG) belongs to the epidermal growth factor (EGF) family, which binds to the epidermal growth factor receptor (EGFR) to regulate the immune response of the host during infections. Our ... Read more >>

BMC Med Genet (BMC medical genetics)
[2019, 20(1):7]

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Evaluation of the VITEK MS knowledge base version 3.0 for the identification of clinically relevant Mycobacterium species.

LiuLin Luo, Wen Cao, WeiWei Chen, RanRan Zhang, LinJie Jing, HuiPing Chen, FangYou Yu, Jun Yue,

Different Mycobacterium spp. infections may indicate varied treatment regimens in the clinic. Thus, the species-level identification of Mycobacterium spp. is one of the most important tasks for a clinical microbiology laboratory. Although matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has emerged as a rapid and accurate method ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2018, 7(1):114]

Cited: 3 times

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[Treatment of thoracolumbar burst fractures with intelligent inflated reduction combined with percutaneous pedicle screw fixation].

Rong-Xue Shao, Bao-Ying Chen, Hui Zhou, Hao Pan, Jun Yue, Hui-Guo Chen, He-Jie Yang, Qing-Feng Hu, Ren-Fu Quan,

<h4>Objective</h4>To evaluate the clinical outcome of intelligent inflated reduction combined with percutaneous pedicle screw fixation in treating thoracolumbar burst fractures.<h4>Methods</h4>The clinical data of 22 patients with thoracolumbar burst fractures of single segment treated from January 2013 to December 2015 were retrospectively analyzed. There were 12 males and 10 females, aged ... Read more >>

Zhongguo Gu Shang (Zhongguo gu shang = China journal of orthopaedics and traumatology)
[2018, 31(8):698-702]

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[Effects of dark induced senescence on the function of photosystem II in flag leaves of winter wheat released in different years.]

Cheng Yang, De Qi Zhang, Si Meng Du, Yun Hui Shao, Bao Ting Fang, Xiang Dong Li, Jun Qin Yue, Su Yu Zhang,

Cultivar renewing is important for the increases of wheat yield. Studying changes of different physiological characteristics in the succession process of wheat varieties has great implications for future breeding. The senescence rate of flag leaf is a key factor affecting winter wheat yield. The variation of photosystem II function during ... Read more >>

Ying Yong Sheng Tai Xue Bao (Ying yong sheng tai xue bao = The journal of applied ecology)
[2018, 29(8):2525-2531]

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[Effects of irrigation regimes on photosynthesis, water use efficiency and grain yield in winter wheat].

Fu Ju Ma, Cheng Yang, De Qi Zhang, Jun Qin Yue, Han Fang Wang, Yun Hui Shao, Bao Ting Fang, Xiang Dong Li,

The effects of different irrigation regimes on photosynthesis, plant growth, water use efficiency (WUE), and grain yield in winter wheat were examined in a common garden with rainout shelter during 2013-2014 and 2014-2015 growing seasons. The experiment consisted of two irrigation timings, jointing stage (J) and anthesis (F), and three ... Read more >>

Ying Yong Sheng Tai Xue Bao (Ying yong sheng tai xue bao = The journal of applied ecology)
[2018, 29(4):1233-1239]

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Whole-exome sequencing identifies a novel homozygous frameshift mutation in the PROM1 gene as a causative mutation in two patients with sporadic retinitis pigmentosa.

Sanmei Liu, Lan Xie, Jun Yue, Tao Ma, Chunyan Peng, Biyuan Qiu, Zhenglin Yang, Jiyun Yang,

Retinitis pigmentosa (RP) refers to a heterogeneous group of inherited retinal diseases caused by the loss of photoreceptors. The present study aimed to identify the gene mutations responsible for RP in two patients diagnosed with sporadic RP using next-generation sequencing technology. For this purpose, two patients with sporadic RP and family ... Read more >>

Int J Mol Med (International journal of molecular medicine)
[2016, 37(6):1528-1534]

Cited: 1 time

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Mismatch repair deficiency is associated with MSI phenotype, increased tumor-infiltrating lymphocytes and PD-L1 expression in immune cells in ovarian cancer.

Xue Xiao, Dandan Dong, Wenjing He, Linhong Song, Qiao Wang, Jun Yue, Lan Xie,

<h4>Objective</h4>The role of mismatch repair (MMR) deficiency in ovarian cancer (OC) pathogenesis and its association with other clinicopathologic features, such as microsatellite instability (MSI) and expression of checkpoint proteins, remain largely elusive.<h4>Methods</h4>We performed Immunohistochemistry (IHC) for MLH1, MSH2, MSH6 and PMS2 on full-section slides from 419 OCs to assess the ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2018, 149(1):146-154]

Cited: 14 times

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[Clinical efficacy of unilateral percutaneous transfacet screws combined with contralateral pedicle screw versus bilateral pedicle screws fixation in the treatment of the degenerative lumbar disease].

Rong-Xue Hao, Hui Zhou, Hao Pan, Jun Yue, Hui-Guo Chen, He-Jie Yang, Gao-Yong Jia, Dong Wang, Yan Lin, Hua-Zi Xu,

<h4>Objective</h4>To investigate the surgical outcome of unilateral pedicle screw(UPS) after TLIF technique combined with contralateral percutaneous transfacet screw(PTS) fixation vs bilateral pedicle screws(BPS) fixation in treatment of degenerative lumbar disease.<h4>Methods</h4>From January 2009 to June 2012, 46 patients with degenerative lumbar diseases, including 30 males and 16 females with an average ... Read more >>

Zhongguo Gu Shang (Zhongguo gu shang = China journal of orthopaedics and traumatology)
[2017, 30(9):817-822]

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Association of Single-Nucleotide Polymorphism in the Hepcidin Promoter Gene with Susceptibility to Extrapulmonary Tuberculosis.

Li Liang, Huijuan Liu, Jun Yue, Li-Rong Liu, Min Han, Liu-Lin Luo, Yan-Lin Zhao, Heping Xiao,

Hepcidin is a 25-amino acid peptide produced by the liver in response to inflammation and iron overload. It is encoded by the hepcidin antimicrobial peptide (HAMP) gene and plays a key role in innate immunity. Previous studies have reported that a -582 A>G polymorphism in the HAMP promoter (HAMP-P) affects hepcidin ... Read more >>

Genet Test Mol Biomarkers (Genetic testing and molecular biomarkers)
[2017, 21(6):351-356]

Cited: 3 times

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Antigens Rv0310c and Rv1255c are promising novel biomarkers for the diagnosis of Mycobacterium tuberculosis infection.

Liulin Luo, Lin Zhu, Jun Yue, Jianping Liu, Guoyuan Liu, Xuelian Zhang, Honghai Wang, Ying Xu,

This study aimed to identify novel immunogenic epitopes from Mycobacterium tuberculosis (MTB) that could be used in tuberculosis (TB) diagnostics. To determine the diagnostic potential of mycobacterial antigens in serodiagnosis of TB, 256 patients were enrolled in a study and divided into two groups: 126 smear-positive pulmonary TB patients (SPPT) ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2017, 6(7):e64]

Cited: 2 times

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A deep learning framework for financial time series using stacked autoencoders and long-short term memory.

Wei Bao, Jun Yue, Yulei Rao,

The application of deep learning approaches to finance has received a great deal of attention from both investors and researchers. This study presents a novel deep learning framework where wavelet transforms (WT), stacked autoencoders (SAEs) and long-short term memory (LSTM) are combined for stock price forecasting. The SAEs for hierarchically ... Read more >>

PLoS One (PloS one)
[2017, 12(7):e0180944]

Cited: 23 times

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