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Knowledge, attitudes, and practices towards COVID-19 among primary and middle school students during the COVID-19 outbreak period in Beijing: An online cross-sectional survey

Fuyuan Wen, Yi Meng, Han Cao, Juan Xia, Hui Li, Han Qi, Kai Meng, Ling Zhang,

Abstract Purpose: This study investigated the KAP towards COVID-19 and their influencing factors among primary and middle school students during the self-quarantine period in Beijing. Methods: This was a cross-sectional study among students from 18 primary and middle schools in Beijing during March 2020. Stratified cluster sampling was conducted. Demographic ... Read more >>

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Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study.

Rui Huang, Li Zhu, Leyang Xue, Longgen Liu, Xuebing Yan, Jian Wang, Biao Zhang, Tianmin Xu, Fang Ji, Yun Zhao, Juan Cheng, Yinling Wang, Huaping Shao, Shuqin Hong, Qi Cao, Chunyang Li, Xiang-An Zhao, Lei Zou, Dawen Sang, Haiyan Zhao, Xinying Guan, Xiaobing Chen, Chun Shan, Juan Xia, Yuxin Chen, Xiaomin Yan, Jie Wei, Chuanwu Zhu, Chao Wu,

Limited data are available for clinical characteristics of patients with coronavirus disease 2019 (COVID-19) outside Wuhan. This study aimed to describe the clinical characteristics of COVID-19 and identify the risk factors for severe illness of COVID-19 in Jiangsu province, China. Clinical data of hospitalized COVID-19 patients were retrospectively collected in ... Read more >>

PLoS Negl Trop Dis (PLoS neglected tropical diseases)
[2020, 14(5):e0008280]

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Reply to the letter by Beyan et al "Plateletcrit may not be an index for predicting of liver fibrosis in patients with chronic hepatitis B".

Rui Huang, Jian Wang, Juan Xia, Chao Wu,

J. Viral Hepat. (Journal of viral hepatitis)
[2020, 27(7):758]

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Artificial Intelligence Distinguishes COVID-19 from Community Acquired Pneumonia on Chest CT.

Lin Li, Lixin Qin, Zeguo Xu, Youbing Yin, Xin Wang, Bin Kong, Junjie Bai, Yi Lu, Zhenghan Fang, Qi Song, Kunlin Cao, Daliang Liu, Guisheng Wang, Qizhong Xu, Xisheng Fang, Shiqin Zhang, Juan Xia, Jun Xia,

Background Coronavirus disease has widely spread all over the world since the beginning of 2020. It is desirable to develop automatic and accurate detection of COVID-19 using chest CT. Purpose To develop a fully automatic framework to detect COVID-19 using chest CT and evaluate its performances. Materials and Methods In ... Read more >>

Radiology (Radiology)
[2020, :200905]

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The gamma-glutamyl transpeptidase to platelet ratio predicts liver inflammation in chronic hepatitis B with normal or mildly elevated alanine transaminase.

Jian Wang, Juan Xia, Xiaomin Yan, Yue Yang, Jie Wei, Yali Xiong, Weihua Wu, Yong Liu, Yuxin Chen, Bei Jia, Zhong Chen, Zhaoping Zhang, Weimao Ding, Rui Huang, Chao Wu,

BACKGROUND:The gamma-glutamyl transpeptidase (GGT) to platelet ratio (GPR) was proposed as a novel index for predicting liver inflammation in chronic hepatitis B (CHB) patients. We aimed to investigate GPR for predicting significant liver inflammation in CHB patients with normal (≤1×upper limit of normal, ULN) or mildly elevated (≤2×ULN) alanine transaminase ... Read more >>

Clin Res Hepatol Gastroenterol (Clinics and research in hepatology and gastroenterology)
[2020, :]

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A family cluster of SARS-CoV-2 infection involving 11 patients in Nanjing, China.

Rui Huang, Juan Xia, Yuxin Chen, Chun Shan, Chao Wu,

Lancet Infect Dis (The Lancet. Infectious diseases)
[2020, 20(5):534-535]

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Plateletcrit as a potential index for predicting liver fibrosis in chronic hepatitis B.

Jian Wang, Juan Xia, Xiaomin Yan, Yue Yang, Jie Wei, Yali Xiong, Weihua Wu, Yong Liu, Yuxin Chen, Bei Jia, Zhong Chen, Zhaoping Zhang, Weimao Ding, Rui Huang, Chao Wu,

Noninvasive tests (NITs) for liver fibrosis are highly needed for chronic hepatitis B (CHB) patients. We aimed to investigate whether plateletcrit (PCT) could be used as a NIT in predicting liver fibrosis for CHB patients. Five hundred and sixty-seven treatment-naïve CHB patients with available liver biopsies were included. Patients were ... Read more >>

J. Viral Hepat. (Journal of viral hepatitis)
[2020, 27(6):602-609]

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Impacts of contracted endodontic cavities compared to traditional endodontic cavities in premolars

Xia Juan, Wang weidong, Li Zhengmao, Lin Bingpeng, Zhang Qian, Jiang Qianzhou, xuechao Yang,

Abstract Background: This study aims to compare the percentage of dentin removed, instrumentation efficacy, root canal filling and load at fracture between contracted endodontic cavities, and traditional endodontic cavities on root canal therapy in premolars. Methods: Forty extracted intact human first premolars were imaged with micro-CT and randomly assigned to ... Read more >>

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Engineered bacterial biofloc formation enhancing phenol removal and cell tolerance.

Xiao Jia, Shun Zhang, Jiawei Li, Juan Xia, Ruilian Yao, Xinqing Zhao, Bing Wu, Fengwu Bai, Yi Xiao,

A microbial floc consisting of a community of microbes embedded in extracellular polymeric substances matrix can provide microbial resistances to toxic chemicals and harsh environments. Phenol is a toxic environmental pollutant and a typical lignin-derived phenolic inhibitor. In this study, we genetically engineered Escherichia coli cells by expressions of diguanylate ... Read more >>

Appl. Microbiol. Biotechnol. (Applied Microbiology and Biotechnology)
[2020, 104(3):1187-1199]

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Relationship between health literacy and quality of life among cancer survivors in China: a cross-sectional study.

Juan Xia, Peng Wu, Qinglong Deng, Rui Yan, Renren Yang, Binghui Lv, Jiwei Wang, Jinming Yu,

OBJECTIVE:To evaluate the association between health literacy (HL) and quality of life (QOL) among cancer survivors in China. DESIGN:Cross-sectional study in China. SETTING AND PARTICIPANTS:This is a cross-sectional observational study of 4589 cancer survivors aged 18 years and older from the Shanghai Cancer Rehabilitation Club. Participants were enrolled and completed ... Read more >>

BMJ Open (BMJ open)
[2019, 9(12):e028458]

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Red cell distribution width to platelet ratio (RPR) predicts liver fibrosis in patients with autoimmune hepatitis

Huali Wang, Jian Wang, Juan Xia, Xiaomin Yan, Yanhong Feng, Lin Li, Jun Chen, Duxian Liu, Weimao Ding, Yongfeng Yang, Chao Wu, Rui Huang,

Abstract Background Accurately evaluate the stages of liver fibrosis are critical for the management of patients with autoimmune hepatitis (AIH). We evaluated the accuracy of red cell distribution width (RDW) to platelet (PLT) ratio (RPR) in predicting liver fibrosis in AIH patients.Methods One hundred and nineteen AIH patients with liver ... Read more >>

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Red blood cell distribution width for predicting significant liver inflammation in patients with autoimmune hepatitis.

Huali Wang, Jian Wang, Rui Huang, Juan Xia, Lingyun Zuo, Xiaomin Yan, Yongfeng Yang, Chao Wu,

BACKGROUND:Red blood cell distribution width (RDW) was reported to be associated with the severity of liver diseases. We aimed to investigate the association between RDW and severity of liver inflammation in autoimmune hepatitis (AIH). PATIENTS AND METHODS:Ninety-two consecutive AIH patients who underwent liver biopsy during 2016-2017 were included. Liver histology ... Read more >>

Eur J Gastroenterol Hepatol (European journal of gastroenterology & hepatology)
[2019, 31(12):1527-1532]

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HBeAg Negativity Is Associated With More Advanced Liver Fibrosis in Patients With Chronic Hepatitis B: A Propensity Score-Matching Analysis.

Jian Wang, Weihua Wu, Xiaomin Yan, Jie Wei, Kefang Yao, Yue Yang, Yali Xiong, Juan Xia, Yong Liu, Yuxin Chen, Bei Jia, Zhaoping Zhang, Weimao Ding, Rui Huang, Chao Wu,

BACKGROUND:Serum hepatitis B e antigen (HBeAg) status is associated with the progression of chronic hepatitis B (CHB). The authors aimed to investigate the relationship between HBeAg status and liver pathology in CHB patients. METHODS:A total of 683 treatment-naive CHB patients who had undergone liver biopsy were retrospectively enrolled from 2 ... Read more >>

J. Clin. Gastroenterol. (Journal of clinical gastroenterology)
[2019, :]

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Thoracic endovascular aortic repair versus open chest surgical repair for patients with type B aortic dissection: a systematic review and meta-analysis.

Jianping Liu, Juan Xia, Gaowu Yan, Yongheng Zhang, Jing Ge, Lin Cao,

Aim: This meta-analysis study aimed to compare the efficacy and safety of TEVAR versus OCSR for TBAD patients.Methods: We systematically searched PubMed, EmBase, and the Cochrane library to identify studies compared the effectiveness of TEVAR and OCSR in TBAD patients from the inception up to July 2019. The summary results ... Read more >>

Ann. Med. (Annals of medicine)
[2019, 51(7-8):360-370]

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Salivary exosomal miR-24-3p serves as a potential detective biomarker for oral squamous cell carcinoma screening.

Lihong He, Fan Ping, Zhaona Fan, Chi Zhang, Miao Deng, Bin Cheng, Juan Xia,

OBJECTIVES:miRNAs in salivary exosomes are used as novel non-invasive biomarkers for detection strategies of human disease. Here, we aimed to investigate the diagnostic potential of salivary exosomal miRNAs as biomarkers for screening oral squamous cell carcinoma (OSCC) and to explore the underlying mechanisms of OSCC pathogenesis. MATERIALS AND METHODS:Differentially expressed ... Read more >>

Biomed. Pharmacother. (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie)
[2020, 121:109553]

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Channel competition in emitter-plasmon coupling.

Juan Xia, Jianwei Tang, Fanglin Bao, Julian Evans, Sailing He,

When an emitter is close to a plasmonic nanoantenna, besides coupling to the dipolar antenna mode, the emitter also considerably couples to a superposition of the high-order modes, referred to as a pseudomode. We comprehensively investigate the differences between the dipolar mode channel and the pseudomode channel in a representative ... Read more >>

Opt Express (Optics express)
[2019, 27(21):30893-30908]

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Pik3ip1 Is a Negative Immune Regulator that Inhibits Antitumor T-Cell Immunity.

Yichen Chen, Jun Wang, Xi Wang, Xinye Li, Jingjing Song, Juan Fang, Xiangqi Liu, Tao Liu, Dikan Wang, Qunxing Li, Shuqiong Wen, Da Ma, Juan Xia, Liqun Luo, Song Guo Zheng, Jun Cui, Gucheng Zeng, Lieping Chen, Bin Cheng, Zhi Wang,

PURPOSE:Multiple negative regulators restrict the ability of T cells to attack tumors. This work demonstrates the role of PI3K-interacting protein 1 (Pik3ip1) in restraining T-cell responses and antitumor immunity. EXPERIMENTAL DESIGN:An anti-Pik3ip1 mAb was generated to identify the Pik3ip1 expression pattern of hematopoietic cells. Pik3ip1 -/- mice and a Pik3ip1 ... Read more >>

Clin. Cancer Res. (Clinical cancer research : an official journal of the American Association for Cancer Research)
[2019, 25(20):6180-6194]

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Metformin and 4SC-202 synergistically promote intrinsic cell apoptosis by accelerating ΔNp63 ubiquitination and degradation in oral squamous cell carcinoma.

Yuan He, Shanshan Tai, Miao Deng, Zhaona Fan, Fan Ping, Lihong He, Chi Zhang, Yulei Huang, Bin Cheng, Juan Xia,

Oral squamous cell carcinoma (OSCC) is the most common and aggressive epithelial tumor in the head and neck region with a rising incidence. Despite the advances in basic science and clinical research, the overall survival rate of OSCC remains low. Thus finding novel effective therapeutic agents for OSCC is necessary. ... Read more >>

Cancer Med (Cancer medicine)
[2019, 8(7):3479-3490]

Cited: 1 time

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CCL2 promotes cell migration by inducing epithelial-mesenchymal transition in oral squamous cell carcinoma.

Zihang Ling, Xi Yang, Xiaobin Chen, Juan Xia, Bin Cheng, Xiaoan Tao,

BACKGROUND:Although a few studies suggested that the chemokine CCL2 might be involved in the development of oral squamous cell carcinoma (OSCC), the exact mechanism remains unclear. In this study, we aimed to determine the resource of CCL2 in lesions and explored a potential mechanism that CCL2 promotes tumor progression. The ... Read more >>

J. Oral Pathol. Med. (Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology)
[2019, 48(6):477-482]

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Remarkable impact of amino acids on ginsenoside transformation from fresh ginseng to red ginseng.

Zhi Liu, Xin Wen, Chong-Zhi Wang, Wei Li, Wei-Hua Huang, Juan Xia, Chang-Chun Ruan, Chun-Su Yuan,

Background:Amino acids are one of the major constituents in Panax ginseng, including neutral amino acid, acidic amino acid, and basic amino acid. However, whether these amino acids play a role in ginsenoside conversion during the steaming process has not yet been elucidated. Methods:In the present study, to elucidate the role ... Read more >>

J Ginseng Res (Journal of ginseng research)
[2020, 44(3):424-434]

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Green synthesis of Ag/ZnO microplates by doping Ag ions on basic zinc carbonate for fast photocatalytic degradation of dyes.

Juan Xia, Xiaopin Liu, Yunhong Gao, Lei Bai,

The Ag/ZnO microplates, composed by various nanoparticles, were facilely synthesized by calcination of the precursor obtained by ion exchanging between zinc carbonate hydroxide [Zn2(OH)2CO3] and silver nitrate (AgNO3) in a short time. The structures of ZnO and Ag/ZnO were characterized carefully by a series of methods and so on. Especially, ... Read more >>

Environ Technol (Environmental technology)
[2019, :1-7]

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Association between anxiety, depression, and comorbid chronic diseases among cancer survivors.

Rui Yan, Juan Xia, Renren Yang, Binghui Lv, Peng Wu, Wanli Chen, Yaxuan Zhang, Xinyuan Lu, Beibei Che, Jiwei Wang, Jinming Yu,

OBJECTIVE:Cancer survivors (CSs) often face the dual physical burden of cancer and other comorbid chronic disease (CCD) and have a great deal of psychological distress, such as anxiety and depression. However, the association between CCD and psychological problems remain less clear in CS. This study was performed to investigate the ... Read more >>

Psychooncology (Psycho-oncology)
[2019, 28(6):1269-1277]

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Review of the molecular mechanisms of Ganoderma lucidum triterpenoids: Ganoderic acids A, C2, D, F, DM, X and Y.

Chengyuan Liang, Danni Tian, Yuzhi Liu, Han Li, Jialiang Zhu, Min Li, Minhang Xin, Juan Xia,

Ganoderma lucidum is a multi-purpose plant medicine that is homologous to functional food. The most attractive properties of G. lucidum are its immunomodulatory and antitumour activities, which are mainly attributed to the following two major active components: G. lucidum polysaccharides and G. lucidum triterpenoids (GLTs). GLTs are effective as supplemental therapies and improve ... Read more >>

Eur J Med Chem (European journal of medicinal chemistry)
[2019, 174:130-141]

Cited: 3 times

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Combined class I histone deacetylase and mTORC1/C2 inhibition suppresses the initiation and recurrence of oral squamous cell carcinomas by repressing SOX2.

Xueyi Liang, Miao Deng, Chi Zhang, Fan Ping, Hongfei Wang, Yun Wang, Zhaona Fan, Xianyue Ren, Xiaoan Tao, Tong Wu, Jian Xu, Bin Cheng, Juan Xia,

Treatment of oral squamous cell carcinoma (OSCC) remains a challenge because of the lack of effective early treatment strategies and high incidence of relapse. Here, we showed that combined 4SC-202 (a novel selective class I HDAC inhibitor) and INK128 (a selective mTORC1/C2 inhibitor) treatment exhibited synergistic effects on inhibiting cell ... Read more >>

Cancer Lett. (Cancer letters)
[2019, 454:108-119]

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Engineering Zymomonas mobilis for Robust Cellulosic Ethanol Production.

Juan Xia, Yongfu Yang, Chen-Guang Liu, Shihui Yang, Feng-Wu Bai,

Great effort has been devoted to engineering Saccharomyces cerevisiae with pentose metabolism through the oxido-reductase pathway for cellulosic ethanol production, but intrinsic cofactor imbalance is observed, which substantially compromises ethanol yield. Zymomonas mobilis not only can be engineered for pentose metabolism through the isomerase pathway without cofactor imbalance but also ... Read more >>

Trends Biotechnol. (Trends in Biotechnology)
[2019, 37(9):960-972]

Cited: 3 times

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